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  • NIH VideoCast - Recombinant DNA Advisory Committee - September 2015
    • - OSP, NIH (2015/09/11)
    • - Category : Recombinant DNA Advisory Committee
    The Recombinant DNA Advisory Committee is a federal advisory committee that provides recommendations to the NIH Director related to basic and clinical research involving recombinant or synthetic nucleic acid molecules. RAC proceedings and reports are posted to the OBA Web site to enhance their accessibility to the scientific and lay public.

    For more information go to http://osp.od.nih.gov/office-biotechnology-activities/biomedical-technology-assessment/hgt/rac

    NIH VideoCast - Recombinant DNA Advisory Committee - September 2015

  • NIH VideoCast - Aquaporin water channels - from transfusion medicine to malaria
    • - Peter Agre, M.D., Johns Hopkins Malaria Research Institute (2015/09/11)
    • - Category : WALS - Wednesday Afternoon Lectures
    NIH Director???s Wednesday Afternoon Lecture Series

    Biochemical analysis of the Rhesus blood group antigen led to the serendipitous discovery of AQP1, the first molecular water channel. Found throughout nature, aquaporin water channels confer high water permeability to cell membranes. AQP1 has been characterized biophysically, and the atomic structure of AQP1 is known. Identification of the Colton blood group antigen on the extracellular domain of AQP1 allowed identification of rare individuals who are AQP1-null and manifest a subclinical form of nephrogenic diabetes insipidus. Thirteen homologous proteins exist in humans. Some transport only water (aquaporins); others transport water plus glycerol (aquaglyceroporins). These proteins are required for generation of physiological fluids (urine, cerebrospinal fluid, aqueous humor, sweat, saliva, and tears). Involvement of aquaporins in multiple clinical states is becoming recognized???renal concentration, fluid retention, blindness, skin hydration, brain edema, thermal stress, glucose homeostasis, malaria, and even arsenic poisoning. Aquaporins are particularly important in plant biology. This information now provides the challenge of developing new technologies to manipulate aquaporins for clinical or agricultural benefits.

    For more information go to https://oir.nih.gov/wals

    NIH VideoCast - Aquaporin water channels - from transfusion medicine to malaria

  • NIH VideoCast - NIAMS Advisory Council - September 2015
    • - NIAMS, NIH (2015/09/10)
    • - Category : Advisory Board Meetings
    87th Meeting National Arthritis and Musculoskeletal and Skin Diseases Advisory Council

    Stephen I. Katz, M.D., Ph.D., Chair

    NIH VideoCast - NIAMS Advisory Council - September 2015

  • NIH VideoCast - National Center for Advancing Translational Sciences Advisory Council/Cures Acceleration Network Review Board
    • - National Center for Advancing Translational Sciences (2015/09/09)
    • - Category : NCATS Council
    The Sept. 3, 2015, joint meeting of the NCATS Advisory Council and the Cures Acceleration Network (CAN) Review Board will feature presentations by NCATS leadership, members of the Advisory Council and CAN Review Board, and invited guests. Presentations will feature in part new information about the NCATS Tissue Chip for Drug Screening and CTSA programs. Information on NIH and NCATS strategic planning also will be provided. In addition, NCATS staff will present a proposed initiative concept for Council/CAN Review Board consideration and clearance. For more information, visit: https://ncats.nih.gov/advisory/council and https://ncats.nih.gov/advisory/canboard.

    For more information go to http://www.ncats.nih.gov/events

    NIH VideoCast - National Center for Advancing Translational Sciences Advisory Council/Cures Acceleration Network Review Board

  • NIH VideoCast - Annual Safety, Health & Wellness Day 2015
    • - ORS, ORF, Occupational Safety & Health Committee, IC Safety and Health Chairpersons Committee, Laboratory Sustainability Group, and National Cancer Institute, NIH (2015/09/05)
    • - Category : Conferences
    Everyone is welcome to come and enjoy the activities and learn about safety, health and wellness opportunities at the NIH. The Opening Ceremony will recognize IC Safety Chairs for their contributions to safety at NIH. The Guest Speaker is Anita L. Schill, PhD, MPH, MA, Senior Science Advisor, National Institute for Occupational Safety and Health. Topic: Seeking Well-Being Through Work

    For more information go to http://www.ors.od.nih.gov/sr/dohs/HealthAndSafety/Pages/Safety-Health-and-Wellness-Day.aspx

    View the program in PDF format: Click Here

    NIH VideoCast - Annual Safety, Health & Wellness Day 2015

  • NIH VideoCast - Principles of Clinical Pharmacology ~ Introduction to Clinical Pharmacology and Pharmacokinetics Clinical Applications of Pharmacokinetics.
    • - Dr. Juan J.L. Lertora, NIH (2015/09/05)
    • - Category : Principles of Clinical Pharmacology
    The "Principles of Clinical Pharmacology" course is a weekly lecture series covering the fundamentals of clinical pharmacology as a translational scientific discipline focused on rational drug development and utilization in therapeutics. The course is offered annually at the NIH Clinical Center and runs from September through April.

    NIH VideoCast - Principles of Clinical Pharmacology ~ Introduction to Clinical Pharmacology and Pharmacokinetics Clinical Applications of Pharmacokinetics.

  • NIH VideoCast - Advisory Committee on Heritable Disorders in Newborns and Children (Day 1)
    • - Advisory Committee on Heritable Disorders in Newborns and Children (2015/09/04)
    • - Category : Advisory Board Meetings
    ACHDNC provides expert advice and recommendations to the Secretary about the development of newborn screening activities, technologies, policies, guidelines, and programs for effectively reducing morbidity and mortality in newborns and children having, or at risk for, heritable disorders. In addition, the Committee???s recommendations regarding additional conditions/heritable disorders for screening that have been adopted by the Secretary are included in the Recommended Uniform Screening Panel (RUSP) and constitute part of the comprehensive guidelines supported by the Health Resources and Services Administration. The committee is composed of 15 voting members.

    The August 2015 meeting will include
    ??? A final evidence review report on the Adrenoleukodystrophy (ALD) condition nomination for inclusion in the RUSP o The Committee is expected to vote on whether or not to recommend to the Secretary the addition of ALD to the RUSP
    ??? A presentation by the Newborn Screening Technical assistance and Evaluation Program (NewSTEPs) on their activities and the NewSTEPs data repository, a centralized and secure database designed for state newborn screening programs to explore data to meet program needs,
    ??? Updates on the implementation of screening for Severe Combined Immunodeficiency, Critical Congenital Heart Disease, and Pompe Disease
    ??? Updates from workgroups focused on cost analysis in newborn screening, newborn screening timeliness, and pilot studies for evidence-based reviews of conditions.

    Time is allotted on both days for public comments.

    For more information go to http://www.hrsa.gov/advisorycommittees/mchbadvisory/heritabledisorders/

    NIH VideoCast - Advisory Committee on Heritable Disorders in Newborns and Children (Day 1)

  • NIH VideoCast - Advisory Committee on Heritable Disorders in Newborns and Children (Day 2)
    • - Advisory Committee on Heritable Disorders in Newborns and Children (2015/09/03)
    • - Category : Advisory Board Meetings
    ACHDNC provides expert advice and recommendations to the Secretary about the development of newborn screening activities, technologies, policies, guidelines, and programs for effectively reducing morbidity and mortality in newborns and children having, or at risk for, heritable disorders. In addition, the Committee???s recommendations regarding additional conditions/heritable disorders for screening that have been adopted by the Secretary are included in the Recommended Uniform Screening Panel (RUSP) and constitute part of the comprehensive guidelines supported by the Health Resources and Services Administration. The committee is composed of 15 voting members.

    The August 2015 meeting will include
    ??? A final evidence review report on the Adrenoleukodystrophy (ALD) condition nomination for inclusion in the RUSP o The Committee is expected to vote on whether or not to recommend to the Secretary the addition of ALD to the RUSP
    ??? A presentation by the Newborn Screening Technical assistance and Evaluation Program (NewSTEPs) on their activities and the NewSTEPs data repository, a centralized and secure database designed for state newborn screening programs to explore data to meet program needs,
    ??? Updates on the implementation of screening for Severe Combined Immunodeficiency, Critical Congenital Heart Disease, and Pompe Disease
    ??? Updates from workgroups focused on cost analysis in newborn screening, newborn screening timeliness, and pilot studies for evidence-based reviews of conditions.

    Time is allotted on both days for public comments.

    For more information go to http://www.hrsa.gov/advisorycommittees/mchbadvisory/heritabledisorders/

    NIH VideoCast - Advisory Committee on Heritable Disorders in Newborns and Children (Day 2)

  • NIH VideoCast - Council of Concils - September 2015
    • - James M Anderson MD PhD (2015/09/03)
    • - Category : Council of Councils
    The Council of Councils was created by the NIH Reform Act of 2006, and advises on matters related to the policies and activities of DPCPSI, including concept clearance of selected initiatives for Common Fund support and proposed Office of Research Infrastructure Program (ORIP) initiatives. The Council conducts second-level review for selected Common Fund and ORIP initiatives.

    For more information go to http://dpcpsi.nih.gov/council/index

    NIH VideoCast - Council of Concils - September 2015

  • NIH VideoCast - CC Grand Rounds: (1) Checkpoint Inhibition: Biology, Clinical Outcomes, and Opportunities for Enhancement and (2) Immune Checkpoint Inhibition for the Treatment of Thymic Epithelial Tumors: Opportunities and Challenges
    • - (1) Christopher R. Heery, MD, Staff Clinician and Head, Clinical Trials Group, Laboratory of Tumor Immunology and Biology, NCI, NIH and (2) Arun Rajan, MD, Staff Clinician, Thoracic and Gastrointestinal Oncology Branch, NCI, NIH (2015/09/03)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: (1) Checkpoint Inhibition: Biology, Clinical Outcomes, and Opportunities for Enhancement and (2) Immune Checkpoint Inhibition for the Treatment of Thymic Epithelial Tumors: Opportunities and Challenges

    For more information go to http://www.cc.nih.gov/about/grcurrent.html

    NIH VideoCast - CC Grand Rounds: (1) Checkpoint Inhibition: Biology, Clinical Outcomes, and Opportunities for Enhancement and (2) Immune Checkpoint Inhibition for the Treatment of Thymic Epithelial Tumors: Opportunities and Challenges

  • NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Risk-Benefit Analysis in Clinical Research: What is the Role of Equipoise?
    • - Scott Kim, MD, PhD, Senior Investigator, Department of Bioethics, Clinical Center, NIH (2015/09/01)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Risk-Benefit Analysis in Clinical Research: What is the Role of Equipoise?

    For more information go to http://www.cc.nih.gov/about.news.grcurrent.html

    NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Risk-Benefit Analysis in Clinical Research: What is the Role of Equipoise?

  • NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: The Clinical Environment as a Learning Environment: The ACGME Clinical Learning Environmental Review Program
    • - Carl Patow, MD, MPH Regional Vice President, Accreditation Council for Graduate Medical Education, Clinical Learning Environment Review Program, and Clinical Professor of Otolaryngology Head and Neck Surgery, Virginia Commonwealth University (2015/08/26)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Contemporary Issues in Graduate Medical Education: The Clinical Environment as a Learning Environment: The ACGME Clinical Learning Environmental Review Program

    For more information go to http://www.cc.nih.gov/about.news.grcurrent.html

    NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: The Clinical Environment as a Learning Environment: The ACGME Clinical Learning Environmental Review Program

  • NIH VideoCast - Towards Solutions to Experimental and Computational Challenges in Neuroscience
    • - NIH (2015/08/20)
    • - Category : Special
    Drs. Christof Koch and Emery Brown will describe the computational or experimental challenges associated with Big Data in their respective domains of neuroscience. From the basic to applied realms, science is being transformed by the collection of data on increasingly finer resolutions, both spatially and temporally. Storing, accessing, and analyzing these data create numerous challenges as well as opportunities.

    For more information go to https://datascience.nih.gov/events/BRAIN-BD2K

    NIH VideoCast - Towards Solutions to Experimental and Computational Challenges in Neuroscience

  • NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: The Current Reality of Competency-based Medical Education
    • - William F. Iobst, MD, FACP, Vice Dean, Vice President for Academic and Clinical Affairs, The Commonwealth Medical College (2015/08/14)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Contemporary Issues in Graduate Medical Education: The Current Reality of Competency-based Medical Education

    For more information go to http://www.cc.nih.gov/about.news.grcurrent.html

    NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: The Current Reality of Competency-based Medical Education

  • NIH VideoCast - NIH BRAIN Initiative Multi-Council Working Group Meeting - July 2015
    • - NINDS, NIH (2015/08/13)
    • - Category : Advisory Board Meetings
    The purpose of the meeting is to receive feedback and guidance on funding opportunity announcements, submitted applications, and strategic planning for the NIH component of The BRAIN Initiative. The MCWG is comprised of 10 representatives from the Advisory Councils of the 10 participating BRAIN Institutes/Centers (including NINDS), 5 at-large members, and ex officio representatives from the other participating federal agencies. The meeting will also provide an opportunity for private entities/foundations to present on their contribution to BRAIN, including but not limited to: Allen Brain Institute, Kavli, Simons Foundation, HHMI/Janelia Farms. Information presented and gathered at this meeting will support the development of future funding opportunity announcements for the Initiative, set to continue until 2025.

    NIH VideoCast - NIH BRAIN Initiative Multi-Council Working Group Meeting - July 2015

  • NIH VideoCast - How to Die Young at a Very Old Age?
    • - Dr. Nir Barzilai, Albert Einstein College of Medicine, Paul F. Glenn Center for the Biology of Human Aging Research and NIH Nathan Shock Centers of Excellence in the Basic Biology of Aging. (2015/08/13)
    • - Category : Geroscience
    Trans-NIH GeroScience Interest Group

    The Trans-NIH GeroScience Interest Group (GSIG) cordially invites you to its summer seminar, featuring Dr. Nir Barzilai. Dr. Nir Barzilai is the director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health???s (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging. He is the Ingeborg and Ira Leon Rennert Chair of Aging Research, professor in the Departments of Medicine and Genetics, and member of the Diabetes Research Center and of the Divisions of Endocrinology & Diabetes and Geriatrics.

    Dr. Barzilai???s research interests focus on several key mechanisms involved in the biology of aging, including the effects of the environment (mainly nutrients) on extending life and the genetic determinants of lifespan. He discovered the first ???longevity gene??? in humans and is further characterizing the phenotype and genotype of humans with exceptional longevity through a NIH-supported Program Project. He has received numerous grants from several funding agencies, including the National Institute on Aging (NIA), American Federation for Aging Research, and the Ellison Medical Foundation. He has published over 200 peer-reviewed papers, reviews, and textbook chapters. He is an advisor to the NIH on several projects, initiatives, and study sections. He serves on several editorial boards and is a reviewer for numerous scientific journals. Dr. Barzilai has been the recipient of prestigious awards for his research, including the Beeson Fellow for Aging Research, the Ellison Medical Foundation Senior Scholar in Aging Award, the Paul F. Glenn Foundation Award, the NIA Nathan Shock Award, and the 2010 Irving S. Wright Award of Distinction in Aging Research.

    The GeroScience Interest Group (GSIG) was formed to enhance opportunities for discussion of the intersection between the biology of aging and the biology of disease and conditions that are of interest across ICs. It is focused on basic biology, but with a longer view towards translation.

    Please send your questions related to the seminar to kohanskir@mail.nih.gov.

    For more information go to http://sigs.nih.gov/geroscience/Pages/default.aspx

    NIH VideoCast - How to Die Young at a Very Old Age?

  • NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Human Research Protections Beyond the Institutional Review Board (IRB) Unmasking the Ramifications of Data "Fudging" in Human Research Studies
    • - Kristen Grace, MD, PhD. Senior Scientist-Investigator, Department of Health and Human Services Office of Research Integrity, Division of Investigative Oversight (2015/08/08)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Human Research Protections Beyond the Institutional Review Board (IRB) Unmasking the Ramifications of Data "Fudging" in Human Research Studies

    For more information go to http://www.cc.nih.gov/about.news.grcurrent.html

    NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Human Research Protections Beyond the Institutional Review Board (IRB) Unmasking the Ramifications of Data "Fudging" in Human Research Studies

  • NIH VideoCast - Lasker Lessons in Leadership: The Art of Publishing
    • - Dan Littman, MD, PhD (2015/08/07)
    • - Category : Special
    Albert and Mary Lasker Foundation and the International Biomedical Research Alliance

    Lasker Lessons in Leadership is a lecture series aimed at bringing top scientists and medical leaders to the NIH to serve as inspiration for future leadership amongst the MD/PhD and PhD students enrolled in the NIH Oxford-Cambridge Scholars Program and the NIH Lasker Clinical Research Scholars Program.

    Sponsored by the Albert and Mary Lasker Foundation, International Biomedical Research Alliance, NIH Oxford-Cambridge Scholars Program, Certara, and WCG

    For more information go to http://oxcam.gpp.nih.gov

    NIH VideoCast - Lasker Lessons in Leadership: The Art of Publishing

  • NIH VideoCast - Mobile and Personal Technologies in Precision Medicine (Day 2)
    • - NIH Office of the Director (2015/08/05)
    • - Category : Conferences
    The Precision Medicine Initiative (PMI) Working Group of the Advisory Committee to the NIH Director (ACD) is hosting a public workshop on the scientific, methodological and practical considerations to inform the incorporation of mobile and personal technologies in the national research cohort of one million or more volunteers. The workshop will be held at the Intel Corporation campus in Santa Clara, California.

    This workshop builds on the unique scientific questions developed during the April 28???29 workshop, digital health data perspectives shared during the May 28-29 workshop, and the participant engagement and health equity discussions at the July 1-2 workshop.

    For more information on the event, visit: http://www.nih.gov/precisionmedicine/workshop-20150727.htm

    NIH VideoCast - Mobile and Personal Technologies in Precision Medicine (Day 2)

  • NIH VideoCast - David E. Barmes Global Health Lecture: Medical Research and Capacity Building for Development: The Experience of Rwanda
    • - Dr. Agnes Binagwaho, Rwandan Minister of Health (2015/08/05)
    • - Category : David E. Barmes - Global Health
    The National Institute of Dental and Craniofacial Research (NIDCR) and the Fogarty International Center present the 2015 David E. Barmes Global Health Lecture:"Medical Research and Capacity Building for Development: The Experience of Rwanda," delivered by Rwandan Health Minister, Dr. Agnes Binagwaho. The lecture will take place on Wednesday, July 29, at 11:30 a.m. in Masur Auditorium, Clinical Center (Building 10).

    Dr. Agnes Binagwaho, Minister of Health of the Republic of Rwanda, has spoken frequently about the value of research and capacity building at her country???s medical and academic institutions in helping relieve the disease burden that weighs on Rwandan and other LMIC populations.

    Before becoming minister in 2011, she had served as permanent secretary of health, as executive secretary of Rwanda???s National AIDS Control Commission and as a physician in public hospitals for over 15 years. She trained in pediatrics, specialized in emergency neonatology and the treatment of HIV/AIDS, and earned her doctoral degree from the University of Rwanda in 2014. She holds positions at Harvard University and Dartmouth College, where she teaches courses in health equity, HIV/AIDS, information and communication technologies for health, and pediatric care delivery systems.

    NIH supports a range of research and training collaborations with Rwandan scientists, such as clinical trials of an HIV vaccine, development of research skills to study cervical and other cancers, and investigations of how intimate partner violence affects health.

    The David E. Barmes Global Health Lecture series honors the late David Edward Barmes, special expert for international health in the National Institute of Dental and Craniofacial Research (NIDCR).

    Prior to joining NIDCR, Dr. Barmes, a public health dentist and epidemiologist by training, served in senior management positions related to oral health, health promotion, and non-communicable diseases at the World Health Organization in Geneva. The lecture series was established by the NIDCR and Fogarty in 2001 to honor his lifelong dedication to research aimed at improving health for those in low-income countries.

    For more information go to http://www.fic.nih.gov/News/Events/Pages/Barmes-Lecture.aspx

    NIH VideoCast - David E. Barmes Global Health Lecture: Medical Research and Capacity Building for Development: The Experience of Rwanda