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  • NIH VideoCast - Precision Medicine Initiative Working Group Meeting - July 2015 (Day 1)
    • - Office of the Director, NIH (2015/07/03)
    • - Category : Conferences
    Day 1 of a two-day public workshop, hosted by the Precision Medicine Initiative (PMI) Working Group of the Advisory Committee to the NIH Director (ACD), on participant engagement and health equity as they relate to the proposed PMI national research cohort. The workshop will focus on the design of an inclusive cohort, building and sustaining public trust, direct-from-participant data provision, and effective and active participant engagement characteristics of a national research cohort of one million or more volunteers. For more information about this workshop, please go to the workshop page on the PMI website:http://www.nih.gov/precisionmedicine/workshop-20150701.htm

    NIH VideoCast - Precision Medicine Initiative Working Group Meeting - July 2015 (Day 1)

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  • NIH VideoCast - Change in the Biomedical Enterprise: Whether We Want It or Not
    • - Marc W. Kirschner, Ph.D., Harvard Medical School (2015/07/02)
    • - Category : Special
    Marc W. Kirschner, Ph.D., Harvard Medical School, spoke at the NIH Training Directors Committee Annual Workshop about the current state of the biomedical research enterprise in the United States. He dissects some of the variables that have contributed to what he views as its unsustainable growth and explores ways to rethink some fundamental features of the US biomedical research ecosystem.

    NIH VideoCast - Change in the Biomedical Enterprise: Whether We Want It or Not

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  • NIH VideoCast - Hispanic Serving Health Professions Schools Data and Professional Development Workshop (Day 2)
    • - NIH OD, Office of Equity Diversity and Inclusion (2015/07/01)
    • - Category : Hispanic Heritage
    Plenary: Framing a National Agenda in Advancing Hispanic Health

    We must rethink education, research, workforce development, and policy in the health professions to advance Hispanic health and create a healthier nation. This interdisciplinary panel of experts will stimulate innovative thinking and sharing of new perspectives in advancing Hispanic health.

    Moderator:
    Maureen Lichtveld, MD, MPH, President and Professor and Chair Freeport McMoRan Chair of Environmental Policy, Associate Director Population Sciences, Louisiana Cancer Research Consortium, Director GROWH Research Consortium, Director, Center for Gulf Coast Environmental Health Research, Leadership and Strategic Initiatives, Department of Global Environmental Health Sciences, Tulane University School of Public Health and Tropical Medicine

    Speakers:
    Gloria Gonzalez, PhD, Associate Chief Officer for Strategic Partnerships and Policy, Scientific Workforce Diversity, Office of the Director, National Institutes of Health

    Mark Lopez, PhD, Senior Director for Access, Diversity and Inclusion, American Dental Education Association

    Joan Lakoski, PhD, Vice President of Research and Graduate Education, Chief Science Officer, American Association of Colleges of Pharmacy

    Vernell P. DeWitty , PhD, RN, Program Deputy Director, Robert Wood Johnson New Careers in Nursing, American Association of Colleges of Nursing Philip Alberti, PhD, Senior Director of Health Equity Research and Policy, Association of American Medical Colleges

    Harrison C. Spencer, MD, MPH, CPH, President and CEO, Association of Schools and Programs of Public Health

    NIH VideoCast - Hispanic Serving Health Professions Schools Data and Professional Development Workshop (Day 2)

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  • NIH VideoCast - Hispanic Serving Health Professions Schools Data and Professional Development Workshop (Day 1)
    • - NIH Office of the Director, Office of Equity Diversity and Inclusion (2015/06/30)
    • - Category : Hispanic Heritage
    The NIH welcomes students and faculty from the Hispanic Serving Health Professions Schools (HSHPS) to the NIH campus for their Professional Development Workshop. This two-day workshop at the NIH will assist scholars from HSHPS perform analytical studies of public health datasets and enhance their career opportunities.

    9:00 am - Welcome Maureen Lichtveld, MD, MPH, President, Hispanic？？？Serving Health Professions Schools Hannah Valantine, MD, MRCP, FACC Chief Officer for Scientific Workforce Diversity, Office of the Director, NIH

    9:30 am - 10:30 am Lessons and Future of NIH Funded Longitudinal Studies Paul Sorlie, PhD Prevention and Population Sciences Branch, NIH NHLBI Katherine Tucker, PhD College of Health Sciences, University of Massachusetts？？？Lowell Greg Talavera, MD, MPH Graduate School of Public Health, San Diego State University

    NIH VideoCast - Hispanic Serving Health Professions Schools Data and Professional Development Workshop (Day 1)

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  • NIH VideoCast - Transcriptional Regulation of Treg and TH17 Differentiation
    • - Vijay Kuchroo, Ph.D., Harvard Medical School (2015/06/27)
    • - Category : Immunology
    Immunology Interest Group

    Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology and the Director of the Evergrande Center for Immunologic Diseases at Harvard Medical School. Throughout his career, Dr. Kuchroo？？？s primary focus has been to investigate the pathogenic and regulatory mechanisms in autoimmune diseases. His interest in regulatory T cells began during his post-doctoral fellowship in Dr. Martin Dort？？？s laboratory at Harvard Medical School where he analyzed antigen-specificity and requirements for the suppressive activity of regulatory T cells. As an independent investigator, Dr. Kuchroo continued to study the immunoregulatory mechanisms responsible for the prevention of organ specific autoimmunity. His laboratory identified that IL-27 was the primary inducer of IL-10-producing, regulatory Tr1 cells, which could potently suppress development of experimental autoimmune encephalomyelitis (EAE). His laboratory also identified and characterized major players of the TIM (T cell Immunoglobulin and Mucin) family of cell surface receptors: TIM-1, TIM-2, TIM-3 and TIM-4, and delineated their involvement in regulation of immune responses. Dr. Kuchroo has also made significant contributions to our understanding of the biology of CD4+ T helper cells. His laboratory was among the first to describe the molecular and cellular factors that promote differentiation and terminal maturation of TH17 cells. His extensive transcriptional profiling of TH17 cells defined dynamic molecular circuits of 39 regulatory factors that control TH17 differentiation (Nature (2013) 496: 461-468) and also identified the transcriptional signature for pathogenic TH17 cells (Nature Immunology (2012) 13: 991-999). Both studies highlighted novel, potential drug targets for treating TH17-mediated immunopathologies.

    For more information go to http://sigs.nih.gov/immunology/Pages/default.aspx

    NIH VideoCast - Transcriptional Regulation of Treg and TH17 Differentiation

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  • NIH VideoCast - OBSSR 20th Anniversary Research Symposium "Healthier Lives through Behavioral and Social Sciences"
    • - Office of Behavioral and Social Sciences Research, NIH (2015/06/27)
    • - Category : Conferences
    On June 25, the NIH Office of Behavioral Health and Social Sciences (OBSSR) will host a research symposium to commemorate its 20th Anniversary in the most suitable way: by showcasing some of the most impactful research in the behavioral and social sciences over the last two decades, and the most promising and cutting edge approaches that will contribute to better health through treatment and prevention of disease.

    Besides presentations from leading scientists from across the nation, the daylong event will feature scientific posters from NIH institutes, participation from several NIH institute directors and members of the leadership, screening of the ？？？I？？？m a behavioral and social scientist？？？ video series, and several networking opportunities.

    View Agenda, Speakers and other information: http://obssr.od.nih.gov/obssr_20th_anniversary/index.html

    NIH VideoCast - OBSSR 20th Anniversary Research Symposium "Healthier Lives through Behavioral and Social Sciences"

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  • NIH VideoCast - NHLBI Sickle Cell Disease Forum Engaging the Community: Developing Solutions (Day 1)
    • - National Heart, Lung, and Blood Institute, NIH (2015/06/27)
    • - Category : Conferences
    The National Heart, Lung, and Blood Institute hosts a Sickle Cell Disease Forum on June 25-26, 2015 at the National Institutes of Health (NIH) campus in Bethesda, MD. The Forum is designed to bring together sickle cell disease community stakeholders？？？including patients and their families, advocates, health care professionals, researchers, professional and community organizations, policymakers, government agencies, industry, and the media ？？？ to help chart the future of sickle cell disease research.

    Panel sessions will address issues affecting those living with sickle cell disease, as well the potential role of various stakeholders in addressing these issues, including:

    ？？？ Sickle Cell Disease Research: Past, Present, and Future
    ？？？ Managing Sickle Cell Disease Pain
    ？？？ Innovative Care Models
    ？？？ Sickle Cell Disease Transitions
    ？？？ Importance of Clinical Trails

    NIH VideoCast - NHLBI Sickle Cell Disease Forum Engaging the Community: Developing Solutions (Day 1)

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  • NIH VideoCast - NHLBI Sickle Cell Disease Forum Engaging the Community: Developing Solutions (Day 2)
    • - National Heart, Lung, and Blood Institute, NIH (2015/06/27)
    • - Category : Conferences
    The National Heart, Lung, and Blood Institute hosts a Sickle Cell Disease Forum on June 25-26, 2015 at the National Institutes of Health (NIH) campus in Bethesda, MD. The Forum is designed to bring together sickle cell disease community stakeholders？？？including patients and their families, advocates, health care professionals, researchers, professional and community organizations, policymakers, government agencies, industry, and the media ？？？ to help chart the future of sickle cell disease research.

    Panel sessions will address issues affecting those living with sickle cell disease, as well the potential role of various stakeholders in addressing these issues, including:

    ？？？ Sickle Cell Disease Research: Past, Present, and Future
    ？？？ Managing Sickle Cell Disease Pain
    ？？？ Innovative Care Models
    ？？？ Sickle Cell Disease Transitions
    ？？？ Importance of Clinical Trails

    NIH VideoCast - NHLBI Sickle Cell Disease Forum Engaging the Community: Developing Solutions (Day 2)

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  • NIH VideoCast - Joint Meeting of the NCI Board of Scientific Advisors and the National Cancer Advisory Board - June 2015
    • - NCI, NIH (2015/06/26)
    • - Category : NCI Board of Scientific Advisors
    5th Joint Meeting of the NCI Board of Scientific Advisors and the National Cancer Advisory Board

    NIH VideoCast - Joint Meeting of the NCI Board of Scientific Advisors and the National Cancer Advisory Board - June 2015

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  • NIH VideoCast - Define Your Career in Behavioral and Social Sciences
    • - Office of Behavioral and Social Sciences Research, NIH (2015/06/26)
    • - Category : Conferences
    During OBSSR？？？s 20th Anniversary celebrations, we are focusing not only on our accomplishments, but also on fostering the future generations of behavioral and social scientists. On June 24, OBSSR will hold the Define Your Career in Behavioral and Social Sciences event, aimed at those in the early stages of their careers, post-doctoral scholars, doctoral students, and others who are exploring training and careers in the behavioral and social sciences.

    Dr. Robert Kaplan and Dr. Fay L. Cook will open the day？？？s exchanges with an outlook of careers in the behavioral and social sciences, which will be followed by three panel discussions featuring leaders from foundations, professional and research societies, think tanks, NIH institutes and advocacy organizations. Attendees will be able to mingle and talk with the panelists during a networking brown bag lunch.

    For more information go to http://obssr.od.nih.gov/obssr_20th_anniversary/

    NIH VideoCast - Define Your Career in Behavioral and Social Sciences

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  • NIH VideoCast - CC Grand Rounds: Hematopoietic Stem Cell and T Cell Transplantation: Perspectives and Developments
    • - 1) Ronald E. Gress, MD, Chief, Experimental Transplantation and Immunology Branch, NCI, NIH and 2) Crystal L. Mackall, MD, Chief, Pediatric Oncology Branch, NCI, NIH (2015/06/26)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Hematopoietic Stem Cell and T Cell Transplantation: Perspectives and Developments

    For more information go to http://www.nih.gov/about/news/grcurrent

    NIH VideoCast - CC Grand Rounds: Hematopoietic Stem Cell and T Cell Transplantation: Perspectives and Developments

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  • NIH VideoCast - A new day for drug development in neuroscience
    • - Ricardo Dolmetsch, Ph.D., Global Head of Neuroscience, Novartis Institutes for BioMedical Research (2015/06/25)
    • - Category : WALS - Wednesday Afternoon Lectures
    Wednesday Afternoon Lecture Series (WALS)

    Dr. Dolmetsch`s group is responsible for leveraging advances in human genetics to model and treat neuropsychiatric and neurodegenerative diseases. Areas of focus include genomics, induced pluripotent stem cells, and brain circuitry.

    Dr. Dolmetsch joined Novartis in August 2013 from the Stanford University School of Medicine, where he was an associate professor of neurobiology. He was also the senior director of Molecular Networks at the Allen Institute for Brain Research. He studied the molecular roots of autism and other neurodevelopmental disorders, including the role of calcium-channel signaling. His laboratory recently used induced pluripotent stem cells to develop an in vitro model of Timothy syndrome, a rare disease with a variety of symptoms, including the characteristic features of autism.

    For more information go to https://oir.nih.gov/wals

    NIH VideoCast - A new day for drug development in neuroscience

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  • NIH VideoCast - Matilda White Riley Award and Lecture in Behavioral and Social Sciences 2015
    • - Kevin Volpp, M.D., Ph.D., University of Pennsylvania, Jeanne Brooks-Gunn, M.Ed., Ph.D., Columbia University (2015/06/24)
    • - Category : BSSR - Behavioral and Social Sciences
    In 2015, the 8th Annual Matilda White Riley Award and Lecture will be a central feature of the NIH Office of Behavioral and Social Sciences Research 20th Anniversary celebrations. It is fitting that this year？？？s award honors Dr. Kevin Volpp and Dr. Jeanne Brooks-Gunn, two eminent scholars who have made significant contributions to the field of behavioral and social sciences that have furthered the mission of the National Institutes of Health.

    AWARDEES:
    Kevin Volpp
    Professor of Medicine
    Perelman School of Medicine
    Professor of Health Care Management at Wharton School
    University of Pennsylvania, Perelman School of Medicine,
    Division of General Internal Medicine

    Jeanne Brooks-Gunn
    Virginia and Leonard Marx Professor of Child Development and Education,
    Teachers College and College of Physicians and Surgeons, Columbia University
    Co-director, National Center for Children and Families
    Co-director, Columbia University Institute for Child and Family Policy

    For more information go to http://obssr.od.nih.gov/obssr_20th_anniversary/index.html

    NIH VideoCast - Matilda White Riley Award and Lecture in Behavioral and Social Sciences 2015

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  • NIH VideoCast - The Children`s Inn at NIH 25th Anniversary Symposium
    • - The Children`s Inn at NIH (2015/06/23)
    • - Category : Special
    The Children？？？s Inn？？？s 25th Anniversary Symposium will highlight The Inn？？？s history, especially its role in advancing medical research. NIH physicians and families will share their stories and the fascinating scientific advances that have been made in treatment of their diseases. The event will also look ahead to the future of The Inn and the next 25 years of medical discovery.

    For more information go to http://www.childrensinn.org

    NIH VideoCast - The Children`s Inn at NIH 25th Anniversary Symposium

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  • NIH VideoCast - Council of Councils - June 2015
    • - James M Anderson, MD, PhD, NIH (2015/06/23)
    • - Category : Council of Councils
    The Council of Councils was created by the NIH Reform Act of 2006, and advises on matters related to the policies and activities of DPCPSI, including concept clearance of selected initiatives for Common Fund support and proposed Office of Research Infrastructure Program (ORIP) initiatives. The Council conducts second-level review for selected Common Fund and ORIP initiatives.

    For more information go to http://dpcpsi.nih.gov/council/index

    NIH VideoCast - Council of Councils - June 2015

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  • NIH VideoCast - National Center for Advancing Translational Sciences Advisory Council/Cures Acceleration Network Review Board - June 2015
    • - National Center for Advancing Translational Sciences (2015/06/21)
    • - Category : NCATS Council
    The June 18, 2015, joint meeting of the National Center for Advancing Translational Sciences Advisory Council and the Cures Acceleration Network (CAN) Review Board will feature presentations by NCATS leadership, members of the Advisory Council and CAN Review Board, and invited guests. Presentations will feature, in part, new information about the NCATS？？？ Discovering New Therapeutic Uses for Existing Molecules and Clinical and Translational Science Awards programs. The Advisory Council Subcommittee on Partnerships with Pharmaceutical and Biotechnology Companies and Venture Capital Firms also will provide an update. In addition, NCATS staff will present a proposed initiative concept for Council/CAN Review Board consideration and clearance. For more information, visit: http://www.ncats.nih.gov/about/ncats-council/council.html and http://www.ncats.nih.gov/about/can-board/can-board.html.

    For more information go to http://www.ncats.nih.gov/events

    NIH VideoCast - National Center for Advancing Translational Sciences Advisory Council/Cures Acceleration Network Review Board - June 2015

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  • NIH VideoCast - CC Grand Rounds: Gene-Forecast: The Systems Biology of Cardiovascular Health Disparities 2) Tailoring Mobile Health Technology to Improve Cardiometabolic Health in Resource-Limited Neighborhood Environments: A Multi-Level, Community-Based Approach
    • - 1) Gary H. Gibbons, MD, Director, NHLBI and Senior Investigator, Metabolic, Cardiovascular and inflammatory Disease Genomics Branch, NHGRI, NIH and 2) Tiffany M. Powell-Wiley, MD, MPH, Assistant Clinical Investigator, Social Determinants of Obesity and Cardiovascular Risk, Cardiovascular and Pulmonary Branch, NHLBI, NIH (2015/06/19)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: 1) Gene-Forecast: The Systems Biology of Cardiovascular Health Disparities and 2) Tailoring Mobile Health Technology to Improve Cardiometabolic Health in Resource-Limited Neighborhood Environments: A Multi-Level, Community-Based Approach

    NIH VideoCast - CC Grand Rounds: Gene-Forecast: The Systems Biology of Cardiovascular Health Disparities 2) Tailoring Mobile Health Technology to Improve Cardiometabolic Health in Resource-Limited Neighborhood Environments: A Multi-Level, Community-Based Approach

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  • NIH VideoCast - Asymmetric stem cell division in drosophila male germline
    • - Yukiko Yamashita, Ph.D., Associate Professor, University of Michigan; Investigator, Howard Hughes Medical Institute (HHMI) (2015/06/19)
    • - Category : WALS - Wednesday Afternoon Lectures
    Wednesday Afternoon Lecture Series (WALS)

    Adult stem cells continuously supply highly differentiated but short-lived cells, such as blood, skin, intestinal epithelium, and sperm cells, throughout life. To maintain the balance between stem cells and differentiating cells -- a failure of which may lead to tumorigenesis through excess self-renewal or tissue degeneration through excess differentiation -- many stem cells have the potential to divide asymmetrically so that each division produces one stem cell and one differentiating cell.

    Drosophila male germline stem cells (GSCs) serve as an ideal model system to study stem-cell behavior. They reside in the stem-cell niche, which specifies stem-cell identity by sending essential signal(s). Stem cells have elaborate cellular mechanisms to ensure the asymmetric outcome of the division, producing one stem cell and one differentiating cell, which is the key to tissue homeostasis.

    Whereas the stem-cell niche provides essential signals for stem-cell identity and proliferation, it is not well known how the niche signal is limited to stem cells, while other cells in proximity are not misspecified by the niche signaling. Here we show that in Drosophila testis, GSCs extend microtubule-based nanotubes into the hub cells, the major component of the stem-cell niche. We further demonstrate that the nanotube mediates decapentaplegic (Dpp) signaling between the hub and GSCs. We propose that confinement of the Dpp signaling to a spatially limited surface area of the nanotube allows privileged reception of niche-derived signals by stem cells.

    For more information go to https://oir.nih.gov/wals

    NIH VideoCast - Asymmetric stem cell division in drosophila male germline

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  • NIH VideoCast - Fattening Up T Cell Memory
    • - Susan Kaech, Ph.D., Associate Professor of Immunobiology and HHMI Early Career Scientist, Yale University (2015/06/19)
    • - Category : Immunology
    Immunology Interest Group

    Dr. Susan Kaech is Associate Professor of Immunobiology and HHMI Early Career Scientist at Yale University. After receiving her Ph.D. from Stanford University for her studies in the field of developmental biology, Dr. Kaech joined the laboratory of Dr. Rafi Ahmed for her postdoctoral training. During this period, she made seminal discoveries in the area of effector and memory T cell development. In particular, she provided the first molecular and functional profiling of effector and memory CD8+ T cells and identified cellular precursors of long-lived memory CD8+ T cells. She became assistant professor at Yale University in 2004, and was promoted to associate professor in 2009. Her work as independent investigator has profoundly shaped our current understanding of how CD8+ memory T cells are formed. She elucidated key transcriptional regulators that control CD8+ T cell differentiation, such as T-bet, Blimp-1, and STAT3, and she has also identified pivotal cytokines that regulate effector and memory cell fate decisions, including IL-12, IL-10 and IL-21. Dr. Kaech has been a recipient of numerous awards including the Burroughs-Wellcome Foundation Award in Biomedical Science (2003), the Cancer Research Institute Investigator Award (2005), and the Presidential Early Career Award for Scientists & Engineers, NIH (2007).

    For more information go to http://sigs.nih.gov/immunology/Pages/default.aspx

    NIH VideoCast - Fattening Up T Cell Memory

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  • NIH VideoCast - CAHM Scientific Lecture - HIV Latency in Perinatal Infection
    • - Deborah Persaud, Carl Dieffenbach, Rohan Hazra, Dana Sampson, Congresswoman Stacey Plaskett (2015/06/18)
    • - Category : Special
    Caribbean American Heritage Month Commemorative Scientific Lecture

    "HIV Latency in Perinatal Infection: Opportunities and Challenges Towards an HIV Cure"

    In 1996, Congress established Caribbean American Heritage Month (CAHM) to be commemorated each June in recognition of the important contributions of Caribbean Americans to U.S. history and culture. On Monday, June 15, 2015, a native of Guyana, Dr. Deborah Persaud, will deliver a research lecture for NIH`s first-ever CAHM commemorative scientific event.

    Deborah Persaud, MD of the Johns Hopkins Children`s Center and School of Medicine is a distinguished virologist and pediatric HIV researcher who led NIH-funded groundbreaking studies that initially cured the HIV perinatally-infected "Mississippi Baby". For the first time, Dr. Persaud will brief HHS staff on findings from and future directions for her landmark studies, which are funded by both the NIH/NIAID and NIH/NICHD.

    This important event has been organized by the NIH Caribbean American Planning Committee and will feature the following speakers:

    Congresswoman Stacey Plaskett, D-VI - U.S. Virgin Islands delegate to U.S. House of Representatives

    Carl Dieffenbach, NIH/NIAID - Director, Division of AIDS (DAIDS)

    Rohan Hazra, NIH/NICHD - Chief, Maternal and Pediatric Infectious Disease Branch (MPIDB)

    Dana M. Sampson, NIH/OD/OBSSR - Chair, NIH Caribbean American Planning Committee

    Deborah Persaud, Johns Hopkins University - Featured Honoree

    Agenda 2015 CAHM Deborah Persaud lecture Slides

    HHS Leaders Caribbean Americans 2015 Slides

    Bio for Honoree Deborah Persaud Slides

    NIH VideoCast - CAHM Scientific Lecture - HIV Latency in Perinatal Infection

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