전체 8345
-
- NIH VideoCast - RSV Vaccine Workshop (Day 2)
-
- - NIH/FDA (2015/06/04)
- - Category : Conferences
- The purpose of the workshop is to identify obstacles to RSV vaccine development, discuss approaches to alleviating them, and identify gaps in research that could be addressed to enable vaccine development. The meeting will also review the basic science and clinical data that will inform the regulation of products under development including, for example, immune responses to RSV primary infection and reinfection, and the physiology and kinetics of placental antibody transfer as well as discuss progress towards standardization of immunologic agents and assays. Lessons learned from previous clinical trials of RSV vaccines, and polyclonal and monoclonal antibodies used for immune-prophylaxis will be discussed to identify potential serological and clinical endpoints for upcoming pivotal trials.
NIH VideoCast - RSV Vaccine Workshop (Day 2)
-
- NIH VideoCast - Digital Health Data in a Million-Person Precision Medicine Initiative Cohort (Day 1)
-
- - NIH/Vanderbilt University (2015/06/03)
- - Category : Conferences
- Day 1 of a two-day workshop by the Precision Medicine Initiative (PMI) Working Group of the Advisory Committee to the NIH Director (ACD) will host a public workshop on digital health data and research cohort design as they relate to the proposed PMI national research cohort. The workshop will focus on solutions to challenges in the design, composition, and organizational characteristics of a national research cohort of one million or more volunteers. For more information about this workshop, please go to the workshop page on the PMI website:
http://www.nih.gov/precisionmedicine/workshop-20150528.htm
NIH VideoCast - Digital Health Data in a Million-Person Precision Medicine Initiative Cohort (Day 1)
-
- NIH VideoCast - Digital Health Data in a Million-Person Precision Medicine Initiative Cohort (Day 2)
-
- - NIH/Vanderbilt University (2015/06/03)
- - Category : Conferences
- Day 2 of a two day workshop held by the Precision Medicine Initiative (PMI) Working Group of the Advisory Committee to the NIH Director (ACD) will host a public workshop on digital health data and research cohort design as they relate to the proposed PMI national research cohort. The workshop will focus on solutions to challenges in the design, composition, and organizational characteristics of a national research cohort of one million or more volunteers. For more information about this workshop, please go to the workshop page on the PMI website:
http://www.nih.gov/precisionmedicine/workshop-20150528.htm
NIH VideoCast - Digital Health Data in a Million-Person Precision Medicine Initiative Cohort (Day 2)
-
- NIH VideoCast - Rethinking Depression and its Treatment: Perspectives from Studies of Deep Brain Stimulation
-
- - Helen Mayberg, M.D., Emory University (2015/06/02)
- - Category : Neuroscience
- Neuroscience Seminar Series
Dr. Mayberg received a BA in psychobiology from University of California, Los Angeles and an MD from University of Southern California. She is a Board Certified Neurologist, trained at the Neurological Institute of NY at Columbia University and a post-doctoral fellowship in Nuclear Medicine at the Johns Hopkins Medical Institutions.
Dr Mayberg heads a multidisciplinary depression research program dedicated to the study of brain circuits in depression and the effects of various antidepressant treatments measured using a variety of functional and structural imaging tools. The primary focus of the lab to development imaging and physiological based algorithms that will discriminate depressed patient subgroups and optimize treatment selection at all stages of the illness. Imaging findings provided the foundation for development and testing of deep brain stimulation (DBS) of the subcallosal cingulate region (Area 25), a novel intervention for patients with treatment resistant depression.
She was recently named as one of Emory University？？？s ？？？Game Changers？？？ in recognition of her pioneering DBS research which has been heralded as a one of the first hypothesis-driven treatment strategies for a major mental illness. Clinical trials are now ongoing in both North America and Europe. At Emory, DBS studies aim to refine, optimize and extend the potential of this treatment strategy with experiments designed to characterize and define mechanisms mediating DBS response and to develop biomarkers that will improve patient selection, enhance precision of surgical targeting and optimize stimulation parameters.
NIH VideoCast - Rethinking Depression and its Treatment: Perspectives from Studies of Deep Brain Stimulation
-
- NIH VideoCast - ICCVAM Public Forum - May 2015
-
- - NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) (2015/05/30)
- - Category : Advisory Board Meetings
- ICCVAM？？？s goals include promotion of national and international partnerships between governmental and nongovernmental groups, including academia, industry, advocacy groups, and other key stakeholders. To foster these partnerships, ICCVAM holds annual public forums to share information and facilitate direct communication of ideas and suggestions from stakeholders.
The upcoming meeting will begin with presentations by NICEATM and ICCVAM members on current activities related to the development and validation of alternative test methods and approaches for assessing acute systemic toxicity, endocrine activity, vaccine safety, and skin sensitization potential, as well as updates on ICCVAM processes. Following each presentation, there will be an opportunity for participants to ask questions of the ICCVAM members. The agenda also includes time for participants to make public oral statements to inform ICCVAM on topics relevant to its mission and current activities.
This meeting is open to the public with time scheduled for oral public statements and for questions following ICCVAM？？？s and NICEATM？？？s presentations.
For more information go to http://ntp.niehs.nih.gov/go/iccvamforum-2015
NIH VideoCast - ICCVAM Public Forum - May 2015
-
- NIH VideoCast - National Advisory Neurological Disorders and Stroke (NANDS) Council Meeting - May 2015
-
- - National Institute of Neurological Disorders and Stroke, NIH (2015/05/30)
- - Category : National Institute of Neurological Disorders and Stroke
- The 193rd meeting of the National Advisory Neurological Disorders and Stroke Council on May 28, 2015.
For more information go to http://www.ninds.nih.gov/find_people/nands/index.htm
NIH VideoCast - National Advisory Neurological Disorders and Stroke (NANDS) Council Meeting - May 2015
-
- NIH VideoCast - 2015 NIH & FDA Glycosciences Research Day
-
- - NIH Glycobiology Scientific Interest Group & The Food & Drug Administration (2015/05/30)
- - Category : Conferences
- This 2015 NIH & FDA Glycosciences Research Day meeting explores the important roles glycans and the lectins that bind them play in Virology, Immunity, Infection, Development, and Disease.
For more information go to https://meetings.nigms.nih.gov/?ID=19237
NIH VideoCast - 2015 NIH & FDA Glycosciences Research Day
-
- NIH VideoCast - Pain Consortium Symposium 2015 (Day 2)
-
- - NIH (2015/05/29)
- - Category : Conferences
- The NIH Pain Consortium was established to enhance pain research and promote collaboration among researchers across the many NIH Institutes and Centers that have programs and activities addressing pain. The consortium supports initiatives, development of research resources and tools, and hosts events to promote collaboration and highlight advances in pain research.
For more information go to http://painconsortium.nih.gov
NIH VideoCast - Pain Consortium Symposium 2015 (Day 2)
-
- NIH VideoCast - Gene regulatory interactions mediating formation of neural crest stem cells
-
- - Marianne Bronner, Ph.D., Albert Billings Ruddock Professor of Biology and Biological Engineering, California Institute of Technology (2015/05/29)
- - Category : WALS - Wednesday Afternoon Lectures
- Wednesday Afternoon Lecture Series
The neural crest is a population of multipotent, migratory stem/progenitor cells that forms at the border of neural and non-neural ectoderm in vertebrate embryos. These cells then migrate from the neural tube along defined pathways, populate numerous sites, and differentiate into diverse cells types including melanocytes, sensory and autonomic neurons, and the craniofacial skeleton. However, neural crest populations differ along the neural axis with respect to migration pathways and derivatives. For example, cranial neural crest cells give rise to cartilage and bone of the face, whereas those at trunk levels do not. Gene regulatory networks (GRNs) composed of interacting transcriptional regulators and downstream effector genes are thought to confer properties such as multipotency and migratory capacity to nascent neural crest cell populations. GRNs have been characterized for the cranial neural crest, but GRN differences along the body axis are not well understood.
Dr. Bronner`s lab is seeking to gain insight into the GRNs by using axial level specific enhancers to isolate neural crest subpopulations and perform transcriptome analysis. The lab then tests functional connections in the neural crest GRNs by systematically perturbing transcription factors to establish their role in specification and examining the effect of these perturbations on downstream genes in order to establish interrelationships. The results suggest that a series of regulatory circuits is involved in inducing the migratory neural crest cell population, maintaining its stem cell properties for a time, and finally leading to progressive differentiation with both common and differential GRN components present at different axial levels. Ultimately, the genes and genetic subcircuits discovered in this study may be useful targets for therapeutic intervention and for guiding directed differentiation of neural crest stem cells into particular derivatives for the purpose of repair/regeneration.
For more information go to https://oir.nih.gov/wals
NIH VideoCast - Gene regulatory interactions mediating formation of neural crest stem cells
-
- NIH VideoCast - Pain Consortium Symposium 2015 (Day 1)
-
- - NIH (2015/05/28)
- - Category : Conferences
- The NIH Pain Consortium was established to enhance pain research and promote collaboration among researchers across the many NIH Institutes and Centers that have programs and activities addressing pain. The consortium supports initiatives, development of research resources and tools, and hosts events to promote collaboration and highlight advances in pain research.
For more information go to http://painconsortium.nih.gov
NIH VideoCast - Pain Consortium Symposium 2015 (Day 1)
-
- NIH VideoCast - CC Grand Rounds: Ebola: From the Monrovia Medical Unit (MMU) to the ICU
-
- - (1) Richard Childs, MD, Clinical Director and Senior Investigator and Chief, Transplantation Immunotherapy Section, Hematology Branch, NHLBI, NIH and (2) Anthony Suffredini, MD, Deputy Director, Department of Critical Care Medicine, CC, NIH (2015/05/28)
- - Category : Clinical Center Grand Rounds
- CC Grand Rounds: Ebola: From the Monrovia Medical Unit (MMU)to the ICU
For more information go to http://www.cc.nih.gov/about/news.grcurrent.html
NIH VideoCast - CC Grand Rounds: Ebola: From the Monrovia Medical Unit (MMU) to the ICU
-
- NIH VideoCast - CSR Advisory Council Meeting - May 2015
-
- - Drs. Janine Clayton, Luci Roberts, Sally Amero, Noni Byrnes, Richard Nakamura, Amy Rubinstein, Adrian Vancea (2015/05/27)
- - Category : Advisory Board Meetings
- Group gathers to provide advice to the CSR Director
NIH VideoCast - CSR Advisory Council Meeting - May 2015
-
- NIH VideoCast - The GTEx Symposium: All Things Considered - Biospecimens, Omics Data and Ethical Issues (Day 1)
-
- - National Cancer Institute, National Institute for Mental Health, National Human Genome Research Institute, NIH Common Fund (2015/05/27)
- - Category : Conferences
- Co-hosted by the National Cancer Institute (NCI), the National Human Genome Research Institute (NHGRI), the National Institute of Mental Health (NIMH), and the NIH Common Fund, the symposium will highlight the scientific goals of the GTEx program and progress in collecting and analyzing biospecimens from over 25 organ sites from 900 post-mortem donors. This two-day event is designed to inform the research community of the resources and infrastructure that are available for their use.
About GTEx:
The Genotype-Tissue Expression (GTEx) program is a National Institutes of Health (NIH) Common Fund study. The overall goal of the GTEx project is to increase our understanding of how changes in our genes contribute to common human disease, in order to improve health care for future generations. To achieve that goal, GTEx has been collecting and analyzing biospecimens from over 900 post mortem donors. With over 800 cases of the total collection completed and analyzed to date, the GTEx program stands poised to make a significant impact on the understanding of human biology and disease. GTEx is a unique program that can provide a deep understanding of normal gene expression, gene mutation, and variation.
For more information about the GTEx program, please visit:
http://www.genome.gov/gtex
The Symposium:
This two day symposium will cover a broad range of topics that focus on the collection of normal biospecimens for GTEx. Topics include an overview of the GTEx program; the biospecimen challenges for GTEx; establishing the approach for GTEx prospective collections; new systems that were developed to implement the program; ethical, legal, and societal investigations within the program; and scientific outcomes from the work thus far.
For more information go to https://meetings.nigms.nih.gov/Home/Index/19217
NIH VideoCast - The GTEx Symposium: All Things Considered - Biospecimens, Omics Data and Ethical Issues (Day 1)
-
- NIH VideoCast - National Advisory Dental and Craniofacial Research Council - May 2015
-
- - Alicia Dombroski, PhD, NIDCR, NIH (2015/05/27)
- - Category : Advisory Board Meetings
- The mission of the National Institute of Dental and Craniofacial Research (NIDCR) includes the support of basic, clinical and translational research as well as the support of research training and the development of research careers. To help achieve the goals of the NIDCR, the National Advisory Dental and Craniofacial Research Council (NADCRC) has the responsibility of advising, consulting with and making recommendations to the Secretary, DHHS, and the Director, NIDCR, on matters relating to the directions of research, research support, training and career development supported by the Institute. Included in this responsibility is the conduct of the secondary review of research grant applications with a focus on NIDCR scientific program priorities and program balance as well as the conduct of research by the Division of Intramural Research, NIDCR.
NIH VideoCast - National Advisory Dental and Craniofacial Research Council - May 2015
-
- NIH VideoCast - Nucleic Acid Delivery Devices for HIV Vaccines
-
- - Division of AIDS/NIAID/NIH and the Global HIV Vaccine Enterprise (2015/05/27)
- - Category : National Institute of Allergy and Infectious Diseases
- Workshop will review the landscape of past and future technologies for delivering nucleic acid (NA) antigens into target tissues of animal models and humans, with a focus on the prevention and treatment of human immunodeficiency virus / acquired immune deficiency syndrome (HIV/AIDS), among other priority diseases.
NIH VideoCast - Nucleic Acid Delivery Devices for HIV Vaccines
-
- NIH VideoCast - The GTEx Symposium: All Things Considered - Biospecimens, Omics Data and Ethical Issues (Day 2)
-
- - National Cancer Institute, National Institute for Mental Health, National Human Genome Research Institute, NIH Common Fund (2015/05/27)
- - Category : Conferences
- Co-hosted by the National Cancer Institute (NCI), the National Human Genome Research Institute (NHGRI), the National Institute of Mental Health (NIMH), and the NIH Common Fund, the symposium will highlight the scientific goals of the GTEx program and progress in collecting and analyzing biospecimens from over 25 organ sites from 900 post-mortem donors. This two-day event is designed to inform the research community of the resources and infrastructure that are available for their use.
About GTEx:
The Genotype-Tissue Expression (GTEx) program is a National Institutes of Health (NIH) Common Fund study. The overall goal of the GTEx project is to increase our understanding of how changes in our genes contribute to common human disease, in order to improve health care for future generations. To achieve that goal, GTEx has been collecting and analyzing biospecimens from over 900 post mortem donors. With over 800 cases of the total collection completed and analyzed to date, the GTEx program stands poised to make a significant impact on the understanding of human biology and disease. GTEx is a unique program that can provide a deep understanding of normal gene expression, gene mutation, and variation.
For more information about the GTEx program, please visit:
http://www.genome.gov/gtex
The Symposium:
This two day symposium will cover a broad range of topics that focus on the collection of normal biospecimens for GTEx. Topics include an overview of the GTEx program; the biospecimen challenges for GTEx; establishing the approach for GTEx prospective collections; new systems that were developed to implement the program; ethical, legal, and societal investigations within the program; and scientific outcomes from the work thus far.
For more information go to https://meetings.nigms.nih.gov/Home/Index/19217
NIH VideoCast - The GTEx Symposium: All Things Considered - Biospecimens, Omics Data and Ethical Issues (Day 2)
-
- NIH VideoCast - NIGMS Council Open Session - May 2015
-
- - NIGMS, NIH (2015/05/27)
- - Category : Advisory Board Meetings
- This is the public broadcast of the NIGMS May 2015 Open Session of Council
NIH VideoCast - NIGMS Council Open Session - May 2015
-
- NIH VideoCast - CC Grand Rounds: (1) Obesity and Brown Fat: Of Mice and Men and (2) Obesity Management in Adults
-
- - (1) Marc Reitman, MD, PhD Chief, Diabetes, Endocrinology, and Obesity Branch, NIDDK, NIH and (2) Susan Z. Yanovski, MD Co-Director, Office of Obesity Research, NIDDK, NIH (2015/05/23)
- - Category : Clinical Center Grand Rounds
- CC Grand Rounds:Obesity and Brown Fat: Of Mice and Men
For more information go to http://www.cc.nih.gov/about/news.grcurrent.html
NIH VideoCast - CC Grand Rounds: (1) Obesity and Brown Fat: Of Mice and Men and (2) Obesity Management in Adults
-
- NIH VideoCast - NIAID Advisory Council Meeting - May 2015
-
- - Dr. Anthony S. Fauci, Director, NIAID, NIH (2015/05/22)
- - Category : National Institute of Allergy and Infectious Diseases
- Dr. Anthony S. Fauci will address the full council. Dr. John Mascola, Director, Vaccine Research Center will address the full council.
NIH VideoCast - NIAID Advisory Council Meeting - May 2015
-
- NIH VideoCast - Division of Microbiology and Infectious Diseases Subcommittee - May 2015
-
- - NIAID, NIH (2015/05/22)
- - Category : National Institute of Allergy and Infectious Diseases
- Report from Division Director and Division Staff
NIH VideoCast - Division of Microbiology and Infectious Diseases Subcommittee - May 2015
