Development, Differentiation, and Diversity of Innate Lymphoid Cells
2014-10-09
org.kosen.entty.User@1f1d84e
정다정(mrycho)
분야
생명과학
개최일
September 2014
신청자
정다정(mrycho)
개최장소
URL
첨부파일
행사&학회소개
-Introduction
-Identification of ILC1s: More Than Just NK Cells?
-Identification of ILC2s
-ILC3s: Lymphoid Tissue-Inducer Cells and More
-Common Developmental Programs for ILC Fate
-Id2 and ILC Fate
-Promyelocytic Leukemia Zinc Finger Is Transiently Expressed in Helper-like ILC Progenitors
-Helper-like ILCs Require the Transcription Factor GATA-3 for Development
-NFIL3, a Central Transcription Factor for All ILCs?
-Notch and ILC Development
-Differentiation of ILC1s
-Differentiation of ILC2s
-Differentiation of ILC3s
-Conclusions and Perspectives
-References
-Identification of ILC1s: More Than Just NK Cells?
-Identification of ILC2s
-ILC3s: Lymphoid Tissue-Inducer Cells and More
-Common Developmental Programs for ILC Fate
-Id2 and ILC Fate
-Promyelocytic Leukemia Zinc Finger Is Transiently Expressed in Helper-like ILC Progenitors
-Helper-like ILCs Require the Transcription Factor GATA-3 for Development
-NFIL3, a Central Transcription Factor for All ILCs?
-Notch and ILC Development
-Differentiation of ILC1s
-Differentiation of ILC2s
-Differentiation of ILC3s
-Conclusions and Perspectives
-References
보고서작성신청
Innate lymphoid cells (ILCs)는 주로 barrier surfaces에 위치하고 병원체에 대항하여 기관 항상성 유지와 보호에 중요한 역할을 한다. ILCs의 비정상적 활성은 염증 및 자가면역 질환의 발병과 관련이 있다. 최근 연구에 따르면, ILCs는 cNK로 불리는 cytotoxic ILCs와 cytokine-producing helper-like ILCs, 2가지 lineages로 나뉜다 알려졌다. 본 논문은 림프 전구체가 ILCs로 분화하는데 요구되는 전사조절 기작에 대해 알아보고자 한다.