Drug and gene delivery across the blood-brain barrier with focused ultrasound
2016-02-25
org.kosen.entty.User@2a15638e
남권호(kwonho)
분야
개최일
2015.12.10
신청자
남권호(kwonho)
개최장소
URL
첨부파일
행사&학회소개
1. Introduction
1.1. The blood-brain barrier
1.2. Conventional approaches for bypassing the blood-brain barrier
1.3. Opening the blood-brain barrier with focused ultrasound
1.4. Safety and monitoring of blood-brain barrier disruption
1.5. Therapeutic bioeffects of focused ultrasound
2. Drug delivery
2.1. Unencapsulated drug
2.2. Liposomes
2.3. Drug loaded microbubbles
3. Gene delivery
3.1. Naked plasmid delivery
3.2. Adeno-associated virus
4. Polymer-based delivery systems
5. Conclusions and future perspectives
1.1. The blood-brain barrier
1.2. Conventional approaches for bypassing the blood-brain barrier
1.3. Opening the blood-brain barrier with focused ultrasound
1.4. Safety and monitoring of blood-brain barrier disruption
1.5. Therapeutic bioeffects of focused ultrasound
2. Drug delivery
2.1. Unencapsulated drug
2.2. Liposomes
2.3. Drug loaded microbubbles
3. Gene delivery
3.1. Naked plasmid delivery
3.2. Adeno-associated virus
4. Polymer-based delivery systems
5. Conclusions and future perspectives
보고서작성신청
최근들어 초음파 자극을 이용한 뇌혈액관문 약물송달 연구가 활발히 진행되고 있다. 본 논문에서는 미리미터 이하의 정밀도를 가진 집속형초음파시스템과 초음파 반응성 약물송달시스템을 이용하여 중추신경계에 약물 또는 유전자를 전달하고자하는 최근의 연구들을 리뷰하였다.