Macrophage Phenotype and Function in Different Stages of Atherosclerosis
2016-02-25
org.kosen.entty.User@658fd22
강완석(kws2601)
분야
보건의료
개최일
2016 Feb 19
신청자
강완석(kws2601)
개최장소
URL
첨부파일
행사&학회소개
1. Introduction
2. Lesional Macrophages Take on Different Phenotypes Depending on Microenvironmental Cues and Activated Intracellular Signaling Pathways
3. Homeostatic Imbalance in Intracellular Lipids, Metabolites, and Proinflammatory Versus Proresolving Mediators Affects Macrophage Phenotype and Function
4. Transdifferentiation of Smooth Muscle Cells to Macrophage-Like Lesion Cells
5. Role of Macrophages in Lesion Initiation and Progression
6. Role of Macrophages in Advanced Necrotic Lesions
7. Role of Macrophages in Lesion Regression and Resolution
8. Novel Macrophage-Based Treatment Possibilities and Future Directions
9. Translation of Findings From Mouse Studies to Human Disease
2. Lesional Macrophages Take on Different Phenotypes Depending on Microenvironmental Cues and Activated Intracellular Signaling Pathways
3. Homeostatic Imbalance in Intracellular Lipids, Metabolites, and Proinflammatory Versus Proresolving Mediators Affects Macrophage Phenotype and Function
4. Transdifferentiation of Smooth Muscle Cells to Macrophage-Like Lesion Cells
5. Role of Macrophages in Lesion Initiation and Progression
6. Role of Macrophages in Advanced Necrotic Lesions
7. Role of Macrophages in Lesion Regression and Resolution
8. Novel Macrophage-Based Treatment Possibilities and Future Directions
9. Translation of Findings From Mouse Studies to Human Disease
보고서작성신청
대식세포의 유동성과 생물학적 기능은 오래전부터 연구되어왔고 오늘날에도 밝혀지고 있다. 대식세포는 동맥경화의 모든 진행단계에서 중요한 역할을 하고 있기 때문에 각 단계에서 어떤 표현형을 가지고 어떤 역할을 하는지 이해하는 것은 동맥경화의 치료에 있어서 중요하다. 이 논문에서는 병변 대식세포의 표현형과 그에따른 기능적 차이를 설명하였다. 이러한 대식세포의 유동성을 이해하여 동맥경화의 진행단계에 따라 새로운 치료방법을 연구할 단서를 제공할 것으로 생각되어 분석을 추천한다.