Barrier Epithelial Cells and the Control of Type 2 Immunity
2016-03-02
org.kosen.entty.User@45c58086
홍성욱(rozh1030)
행사&학회소개
Introduction
<br>Initiation of Type-2-Cell-Mediated Immunity Requires More than Just Dendritic Cells
<br>Epithelial Cells Produce Chemokines that Recruit DCs,Basophils, and ILC2s
<br>Epithelial Cells Produce Cytokines that Activate DCs,Basophils, and ILC2s
<br>Epithelial-Derived DAMPs and Alarmins Promote Th2-Cell-Mediated Immunity
<br>Pattern Recognition Receptors Prime Type-2-Cell-Mediated Immunity in Epithelial Cells
<br>Altered Epithelial Barrier Function Contributes to Type-2-Cell-Mediated Immunity
<br>Production of Mucus and Mucus-Associated Bioactive Molecules Promote Type-2-Cell-Mediated Immunity
<br>Alterations in EC-Repairing Factors Might Promote Type-2-Cell-Mediated Immunity
<br>Epithelial Cytokines in Human Type-2-Cell-Associated Chronic Inflammatory Diseases
<br>Conclusion
<br>Initiation of Type-2-Cell-Mediated Immunity Requires More than Just Dendritic Cells
<br>Epithelial Cells Produce Chemokines that Recruit DCs,Basophils, and ILC2s
<br>Epithelial Cells Produce Cytokines that Activate DCs,Basophils, and ILC2s
<br>Epithelial-Derived DAMPs and Alarmins Promote Th2-Cell-Mediated Immunity
<br>Pattern Recognition Receptors Prime Type-2-Cell-Mediated Immunity in Epithelial Cells
<br>Altered Epithelial Barrier Function Contributes to Type-2-Cell-Mediated Immunity
<br>Production of Mucus and Mucus-Associated Bioactive Molecules Promote Type-2-Cell-Mediated Immunity
<br>Alterations in EC-Repairing Factors Might Promote Type-2-Cell-Mediated Immunity
<br>Epithelial Cytokines in Human Type-2-Cell-Associated Chronic Inflammatory Diseases
<br>Conclusion
보고서작성신청
Th2 cell, basophil, eosinophil, mast cell, ILC2 등에 의해서 일어나는 2형 면역반응 (Type 2 immunity)는 감염된 기생충의 제거에 중요한 역할을 할 뿐아니라, 천식이나 아토피 피부염과 같은 알레르기 질환이 유발되는 병인기전에서도 중요한 역할을 한다. 기생충 감염 뿐 아니라 주요 알레르기 질환들은 우리몸의 가장 바깥 보호막인 점막층에서 시작되는 경우가 많은데, 본 논문에서는 이런 점막층을 구성하는 상피세포들이 2형 면역반응의 발생에 어떤 역할을 하는지에 대해서 다루고 있다.