The Principles of Engineering Immune Cells to Treat Cancer
2017-03-26
org.kosen.entty.User@3a5e386f
지현배(hj1271)
행사&학회소개
Introduction
Living Therapies Can Uniquely Perform Complex Sensing and Response Functions
Engineered T Cells Represent a Convergence of Diverse Areas of Medicine and Science
Envisioning the Next Generation of T Cell Therapies
Experience with T Cell Therapy: Lessons Learned
The Solid Tumor Challenge
Anti-cancer Cell Therapies Must Solve Multidimensional Challenges
Improving Recognition: New Receptors and Recognition Programs
Driving Proliferation and Persistence
Remodeling the Microenvironment
Engineering Tighter Control Systems in Therapeutic T Cells
Conclusion: Vision of Immune Cell Therapies in Precision Medicine
Living Therapies Can Uniquely Perform Complex Sensing and Response Functions
Engineered T Cells Represent a Convergence of Diverse Areas of Medicine and Science
Envisioning the Next Generation of T Cell Therapies
Experience with T Cell Therapy: Lessons Learned
The Solid Tumor Challenge
Anti-cancer Cell Therapies Must Solve Multidimensional Challenges
Improving Recognition: New Receptors and Recognition Programs
Driving Proliferation and Persistence
Remodeling the Microenvironment
Engineering Tighter Control Systems in Therapeutic T Cells
Conclusion: Vision of Immune Cell Therapies in Precision Medicine
보고서작성신청
Chimeric antigen receptor (CAR) T 세포는 효과적인 새로운 암 치료법으로 엔지니이된 면역 세포를 이용하는 방법이다. 다양한 암을 치료하기 위해 엔지니어된 T 세포를 안전하고 효과적인 프랫폼으로 만들기 위해 임상적 시도가 진행되고 있다. 합성 생물학 접근법은 면역세포를 프로그램화하기 위해 다양한 기술을 제공하고 있다. 이 리뷰 논문은 차세대 T 세포 치료제의 디자인을 위한 기술들을 소개하고 있다. 따라서 이번 논문은 T 세포 치료제에 관심이 있는 연구자들에게 유용한 정보를 제공하고 있다.