Toward practical application of paper-based microfluidics for medical diagnostics: state-of-the-art and challenges
2017-04-02
org.kosen.entty.User@2ff45b38
김성재(gatechem)
분야
생명과학
개최일
2017년 4월
신청자
김성재(gatechem)
개최장소
URL
행사&학회소개
Introduction
Paper-based devices in the market
Dipsticks
Lateral flow immunochromatographic assays (LFIAs)
Key of success of commercialized paper-based devices
Room for advances in commercialized paper-based devices
General state-of-the-art of μPADs
User operation for simple health check μPADs
Separation
Mixing and reagent addition
Influence of sample volume
Control of sample delivery volume
Simplified signal readout and result interpretation
Quantitative signal readout
Semi-quantitative signal readout
Selection of detection techniques
Colorimetry
Electrochemical detection
Chemiluminescence
Fluorescence
Electrochemiluminescence
Photoelectrochemical detection
Storage stability
Non-reducing sugars
Silica sol？gel materials
Mass production
Microfluidic structure patterning
Deposition of assay components
Assembly of multi-layered configurations
State-of-the-art of μPADs in the market
3D-μPAD for ALT testing and micronutrients (Diagnostics For All)
Paper machine for nucleic acid testing (Diagnostics For All)
Text-reported blood typing (Haemokinesis)
LFIA device for infectious disease testing (INSiGHT)
Conclusions
Paper-based devices in the market
Dipsticks
Lateral flow immunochromatographic assays (LFIAs)
Key of success of commercialized paper-based devices
Room for advances in commercialized paper-based devices
General state-of-the-art of μPADs
User operation for simple health check μPADs
Separation
Mixing and reagent addition
Influence of sample volume
Control of sample delivery volume
Simplified signal readout and result interpretation
Quantitative signal readout
Semi-quantitative signal readout
Selection of detection techniques
Colorimetry
Electrochemical detection
Chemiluminescence
Fluorescence
Electrochemiluminescence
Photoelectrochemical detection
Storage stability
Non-reducing sugars
Silica sol？gel materials
Mass production
Microfluidic structure patterning
Deposition of assay components
Assembly of multi-layered configurations
State-of-the-art of μPADs in the market
3D-μPAD for ALT testing and micronutrients (Diagnostics For All)
Paper machine for nucleic acid testing (Diagnostics For All)
Text-reported blood typing (Haemokinesis)
LFIA device for infectious disease testing (INSiGHT)
Conclusions
보고서작성신청
종이기반의 미세유체역학 분석 장치 (uPADs)는 지난 10여년간 진단 분야에서 급부상하고 있는 플렛폼이다. 이 분야에 대해 연구는 활발히 되고 있는 반면, 실제 상용화된 uPAD는 아직까지 거의 전무하다. 이러한 모순은 연구에서 간과하고 있는 동작 단순화, 장시간 안정성, 부수적 장치들이 상용화의 걸림돌이 되고 있다. 이러한 배경에서부터 본 원문에서는 1) 상용화에 성공한 uPAD의 분석, 2) uPAD 상용화의 걸림돌, 3) uPAD의 대량 생산성에 대해 상세히 다루고 있다. 따라서 본 분석은 미세유체역학 장치 전반에 대해 연구하는 연구자에게 매우 유용한 분석이 될 것이다.