KOSEN 한인과학기술자네트워크

STD Prevention Primary Sponsor: Centers for Disease Control Deadline: 4/1/2001; 8/1/2001; 12/1/2001 KEYWORDS The Division of STD Prevention The Division of STD Prevention provides national leadership through research, policy development, and support of effective services to prevent sexually transmitted diseases (including HIV infection) and their complications such as enhanced HIV transmission, infertility, adverse outcomes of pregnancy, and reproductive tract cancer. We assist health departments, health-care providers, and non-governmental organizations and collaborate with other governmental entities through the development, synthesis, translation, and dissemination of timely, science-based information; the development of national goals and science-based policy; and the development and support of science-based programs that meet the needs of communities. Develop a urine-based diagnostic test that can be performed in the clinic to detect both genital chlamydia and gonorrhea at the time of the client’s visit. Bob Johnson Program Coordinator (404) 639-1894, Fax: (404) 639-8610 Email: RJohnson@cdc.gov Develop a saliva-based test to reliably detect antibody to HSV-2. Lauri Markowitz Program Coordinator (404) 639-8359, Fax: (404) 639-8610 Email: LMarkowitz@cdc.gov Develop appropriate mailing packages for vaginal swabs (to collect specimens to be tested for chlamydia, gonorrhea, and other STD organisms by amplification techniques) with appropriate accompanying materials and information. Julia Schillinger Program Coordinator (404) 639-1895, Fax: (404) 639-8610 Email: JSchillinger@cdc.gov Develop a bacterial vaginosis (BV) screening test for home use by patients. This test would check for vaginal fluid pH and vaginal fluid amines, which would then enable patients to personally detect BV. Emily Koumans Program Coordinator (404) 639-1897, Fax: (404) 639-8610 Email: EKoumans@cdc.gov. Develop and evaluate the effectiveness of a video for physicians that will: (1) increase their index of suspicion for syphilis, (2) motivate them to support the National Plan to Eliminate Syphilis from the United States, (3) educate them about the need to quickly report positive syphilis test results to the health department, and (4) educate them about counseling issues related syphilis. Educating public and private physicians in areas with high syphilis morbidity (HMAs - high morbidity areas) is important to accomplish the goals and objectives of the National Plan to Eliminate Syphilis from the United States. A nationwide survey of primary care physicians found them to be lacking in STD test reporting and counseling knowledge. Additionally, because syphilis is at very low rates, many primary care physicians do not routinely encounter patients with syphilis and may exclude syphilis in their differential diagnosis. For syphilis elimination to become a reality, public and private physicians must be motivated to appropriately test for syphilis and to promptly report positive test reports to the health department for quick intervention to break the chain of infection. Develop and evaluate the effectiveness of a video targeted to community-based organizations (CBOs) that will motivate them to become partners in STD prevention activities at the local level. The video should include basic information on the most prevalent STDs, why it is important to prevent STDs, and examples of "best practice" collaborations between CBOs and governmental agencies. Develop and evaluate the effectiveness of videotapes or other educational materials to help consumers talk to their health care providers about STDs. Materials should be developed for both males and females and should be appropriate for viewing or reading in a clinic or private office waiting room. Since it has long been known that health care providers often to not address sensitive topics, such as STDs, with their patients, this approach seeks to enable the consumer to initiate such a dialogue. Develop a CD-rom, audiotape, video-tape or self-instruction manual that will assist non-Spanish speaking health care providers in obtaining sexual histories and providing STD education/counseling to Spanish-speaking clients. Develop interactive software to update health care providers on current approaches for the diagnosis and treatment of STDs. Donna Anderson Program Coordinator (404) 639-8358, Fax: (404) 639-8609 Email: DAnderson@cdc.gov Phase 1 Develop a media campaign targeting adolescents that informs/encourages youth about the need to get tested for sexually transmitted diseases, where to go for testing, and addresses the issues of confidentiality of results and treatment. The campaign includes television, radio and billboard and Internet media. Campaign messages will be developed by a team of adolescents, ages 13-19, and use appropriate language and images. The campaign provides a hotline telephone number for adolescents to call to be referred to a nearby provider or clinic where they could be tested and treated, if necessary. Phase 2 Evaluate the effectiveness of the media campaign in communities where the campaign is implemented versus communities, matched on sociodemographics and STD rates among adolescents, in which it was not implemented. Key outcome variables would include numbers of calls to hotline telephone number and increased numbers of STD tests performed with adolescents at clinics or providers to which adolescents were referred. Kathleen Ethier Program Coordinator (404) 639-8299, Fax: (404) 639-8874 Email: KEthier@cdc.gov Phase I Develop an interactive CD-ROM to (1) obtain in-depth sexual histories from patients, and (2) deliver, enhance, and reinforce STD prevention counseling. The CD-RO supplements current, standard-of-care history-taking and counseling practices in clinical settings serving adolescent patients, such as public health clinics, STD clinics, and private practice settings. The sexual history component will present questions in a manner that takes into account the sensitivity of the topic. The counseling component will be responsive and tailored to each patient’s developmental level, demographic profile, and readiness for behavior change. The objectives of the CD-ROM would be to (1) obtain sexual history information via audio-enhanced computer-assisted self-interview (audio-CASI), (2) provide individually- tailored sexual risk reduction messages (e.g., the importance of condom use, instruction in correct condom use); (3) evaluate patients’ comprehension of knowledge gains through corrective feedback; (4) provide tailored messages to promote internalization of prevention messages (e.g., assessment of barriers to condom use, perceived norms regarding condom use). Phase II Evaluate the counseling CD-ROM by comparison of samples of patients who receive the computer delivered counseling with those who do not. Key outcome variables include condom use and STD infection and/or re-infection. Catlainn Sionean Program Coordinator (404) 639-1820, Fax: (404) 639-8874 Email: CSionean@cdc.gov Mary McFarlane (404) 639-8309, Fax: (404) 639-8874 Email: MMcFarlane@cdc.gov Phase I Develop a video designed to train health care providers (e.g., physicians, nurses, disease intervention specialists) to conduct a thorough, appropriate HIV/STD risk assessment during a standard office visit. This 20-30 minute video would target health care providers in both the public and private sectors. The video would focus both on what constitutes an HIV/STD risk assessment (e.g., sexual history, drug use, STD history) and the communication skills providers need to effectively interact with their clients during the assessment. Innovative instructional methods as well as skits designed to demonstrate sensitive/insensitive techniques should be included. The video could be marketed toward public clinics such as STD, HIV, and family planning clinic staff, and private sector health care providers including large managed care organizations. Phase II Evaluate the video by comparing provider and client perceptions of the information given during the visit, client behaviors obtained via self-administered questionnaire, and their comfort with the process. Data would be compared to a control group of health care providers who did not receive the video training. Evaluation should also include clients’ assessment of the patient-provider interaction. Key outcome variables would include sexual behavior, condom use, and drug use. Jami Leichliter Program Coordinator (404) 639-1821, Fax: (404) 639-8874 Email: JLeichliter@cdc.gov Factorial survey research techniques have the potential to be useful across the spectrum of public health research, but the field lacks useful and widely available software with which to construct these surveys. Phase I Developing software for a survey tool. The logic model for factorial survey construction is such that there exists (1) x number of variables, with (2) y levels of each variable, and (3) some response scale. Phase I entails developing a software program encompassing this logic model with four essential goals. First, the format will enable the user to construct a variable number of items with variable levels within each item, and a response scale. Second, the program will permit a (1) random distribution of items and/or levels, and (2) a user-defined pattern of items and/or levels. Third, the program will either have a complete statistical analysis program attached or be compatible with commonly used existing software (e.g., SAS, SPSS). Fourth, the software will be at least sufficiently user-friendly such that a public health professional with access to guides and/or manuals can construct a useful survey. Phase II Evaluation of the completed survey tool. Achievement of the first three goals will be demonstrable by the end of Phase I. For public health professionals to adopt the survey tool, it will be necessary to show that surveys generated by the software are empirically useful to researchers and usable in the field. Therefore, one or more field tests will be prescribed, in which the software meets the following four goals. First, the survey developers are able to use the software accurately. Second, survey administrators are able to disseminate the survey accurately. Third, respondents provide data with as few missing responses and as high a response rate as with traditional surveys. Fourth, resulting data will be as objectively useful to public health professionals (research and program) as data gathered via traditional methods. Matthew Hogben Program Coordinator (404) 639-1833, Fax: (404) 639-8874 Email: MHogben@cdc.gov Given the current effort to eliminate syphilis in the US, it would be advantageous to develop educational materials that target syphilis prevention and treatment as well as the broader impact that syphilis prevention has on the incidence of HIV. Phase I Develop a risk awareness and reduction video that illustrates syphilis risk identification, transmission, symptoms, screening, treatment, partner services, behavioral risk reduction change, maintenance and the role of syphilis in HIV transmission. The video would primarily target people who utilize health care settings where they could obtain screening and treatment for syphilis, HIV and other sexually transmitted diseases. However, the video can also be used in settings where counseling and referrals for syphilis testing can be offered. The video will include factual information, storytelling and accounts of personal risk experiences to illustrate the impact that syphilis infection and its prevention on HIV incidence, patients, partners, relationships, and communities. Phase II Evaluate the video by comparing sites that utilize the video with sites do not. Evaluation includes patient receptivity to testing for syphilis, requests for information and condoms, and participation in the partner notification process. Outcome variables include syphilis testing, patient knowledge and attitudes, patient partner index, risky and risk reducing behaviors, and subsequent STD testing. Samantha Williams Program Coordinator (404) 639-1825, Fax: (404) 639-8874 Email: SWilliams@cdc.gov Existing training manuals and curricula for rapid ethnographic assessment often recommend consultation with an experienced ethnographer at some time during the process. Phase I Develop a curriculum for use by health educators at local health departments, clinics, community based organizations, and other agencies or organizations that deliver STD prevention and treatment services. The curriculum will target small scale rapid assessment of STD prevention and treatment needs and provide sufficient content to eliminate the necessity of consultation with an expert in ethnographic methods. Content will include definition of problem and target population, data collection and analysis methods, and presentation strategies. The curriculum will define goals and measurable objectives. Elements or activities will be linked to the methodological framework. Phase II Evaluate the curriculum by conducting a pilot demonstration to show how goals and measurable objectives are achieved. Key outcome variables include educator and participant variables such as completeness of content coverage in allotted time, effectiveness of teaching, performance of tasks following participation in curriculum. Frederick Bloom Program Coordinator (404) 639-8278, Fax: (404) 639-8874 Email: FBloom@cdc.gov For additional information on research topics, contact: For administrative and business management information contact: Joanne Wojcik Centers for Disease Control and Prevention Procurement and Grants Office Mail Stop E13 2920 Brandywine Road Atlanta, GA 30341 (770) 488-2717; Fax: (770) 488-2777 Email: jcw6@cdc.gov NOTE: The Solicitations listed on this site are partial copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should always use the suggested links on our reference pages. These will take you directly to the appropriate agency information where you can read the official version of the solicitation you are interested in. The official link for this page is: http://grants.nih.gov/grants/funding/sbir.htm. Solicitation closing dates are: April 1, August 1, and December 1, 2001