KOSEN 한인과학기술자네트워크

닫기

더 많은 혜택을 위해
로그인 하세요.

동향

동향

안전성 및 약효 분석·평가 기술-GPCR as potential target for drug discovery

2004-02-01 org.kosen.entty.User@e17707b 한상배(sbhan2023)

분야

과학기술과 인문사회

첨부파일

G-protein coupled receptors (GPCRs) represent by far the largest class of targets for targets for morden drugs. Virtually all therspeutics that are directed towards GPCRs have been designed using assays that presume that these receptors are monomeric. The recent realization that these receptors from homo-oligomeric and heteroligomeric complexs has added a new dimension to rational drug design. However, this important aspect of GPCR biology remains largely unincorporated into schemes to search for new therapetics. This review provides a synopsis of the current thinking surrounding GPCR homooligomerization and heterooligomerization and shows how new models point towards unexplored avenues in the development of new therapies.
한상배

한상배(sbhan2023)

미국국립보건원

추천 리포트

리포트 평점  
해당 콘텐츠에 대한 회원님의 소중한 평가를 부탁드립니다.
0.0 (0개의 평가)
평가하기
등록된 댓글이 없습니다.
목록
목록