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  • Complex Genetics in the Human Brain: Lessons from COMT
    • - Daniel R. Weinberger, M.D., National Institute of Mental Health (2010/03/04)
    • - Category : Wednesday Afternoon Lectures

    For more information, visit
    http://intramural.nimh.nih.gov/research/pi/pi_weinberger.html

    The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Complex Genetics in the Human Brain: Lessons from COMT

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  • Great Teachers - Prostate Cancer
    • - Ian M. Thompson, M.D., University of Texas Health Science Center (2010/03/04)
    • - Category : Clinical Center Grand Rounds
    NIH Clinical Center Grand Rounds

    For more information, visit
    http://clinicalcenter.nih.gov/about/news/grcurrent.shtml

    Great Teachers - Prostate Cancer

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  • Green Purchasing for Purchase Card Holders (HHS-Only)
    • - Dana Arnold, Office of the Federal Environmental Executive (2010/03/04)
    • - Category : HHS Only
    Green Purchasing for Purchase Card Holders and Contract Staff

    These sessions are for government purchase card users, card approving officials and contract staff. The sessions provide an introduction to the Federal “green” purchasing program. The Federal government has requirements to purchase products with environmental and energy attributes. Also known as “green” purchasing, this program requires the purchasing of recycled content products, energy-efficient products and renewable energy technologies, alternative fuel vehicles and alternative fuels, biobased products, environmentally preferable products and services and non-ozone depleting substances.

    Green Purchasing uses CIT's Accordent system. The presentation synchronize video to PowerPoint web images and moves caption text under the video window, all within an embedded browser. Pop-up blockers, anti-spyware and personal firewalls can interfere, so check or turn off. If you still have a problem, install the latest version of RealPlayer software and re-boot your computer. Use Internet Explorer 7.0 or higher for Windows and Safari 2.0.4 or higher for Macintosh.

    Green Purchasing for Purchase Card Holders (HHS-Only)

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  • Transcriptional Control of Immunological Tolerance
    • - Diane Mathis, Ph.D., Harvard Medical School (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    Humans expressing a defective form of the transcription factor autoimmune regulator develop multi-organ autoimmune disease. Mice deficient in aire were engineered in order to test the hypothesis that this transcription factor controls autoimmunity by promoting the ectopic expression of peripheral-tissue antigens in thymic epithelial cells. This hypothesis proved correct as the mutant animals exhibited a variety of autoimmune manifestations, dependent on thymic stromal cells, and reflective of reduced or absent thymic transcription of genes encoding peripheral-tissue antigens. In short, peripheral antigenic self is foreshadowed in the thymus, under the dictates of aire.More recently, the cellular mechanism of aire???s influence on immunological tolerance has been explored.

    For more information, visit
    http://www.hms.harvard.edu/dms/immunology/fac_mathis.html


    WALS

    Transcriptional Control of Immunological Tolerance

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  • Celebrating Plain Language at the NIH 2005
    • - Viorst, Judith.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Special

    Celebrating Plain Language at the NIH 2005

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  • Advances in Pediatric Oncology
    • - Helman, L.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Special

    Advances in Pediatric Oncology

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  • Recent Advances in Prophylactic HPV Cervical Cancer Vaccines (NIH-Only)
    • - John T. Schiller, Ph.D., Center for Cancer Research, NCI (2010/03/04)
    • - Category : NCI CCR Grand Rounds (NIH Only)
    Center for Cancer Research - National Cancer Institute Grand Rounds

    The primary educational objective of these seminars is to provide new information, ideas, and discussion about timely areas of research with impact on the field of oncology. A secondary educational objective is to elicit participation by individuals from all divisions of the intramural NCI, and thus facilitate more interactions among investigators and groups in the NCI.

    Please note - CCRNCI lectures are not archived and are available for viewing in real time only.

    Recent Advances in Prophylactic HPV Cervical Cancer Vaccines (NIH-Only)

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  • The Bio Bar Code Assay: Changing The Playing Field In Cancer Diagnostics
    • - Mirkin, Chad A.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : NCI Nanotechnology

    The Bio Bar Code Assay: Changing The Playing Field In Cancer Diagnostics

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  • Neurodegeneration: Too Much of a Good Thing Kills You
    • - John Hardy, Ph.D., National Institute on Aging (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    For many neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, there are rare genetic forms of the disease and more common sporadic forms.?? Over the last 15 years, we have found all the genes involved in the rare genetic forms, but we have made little progress in understanding the causes of the more common sporadic cases.?? Over the last 5 years, we have shown that genetic variability in the amount of expression of the genes involved in the rare forms of the disease are a risk factor for the development of the sporadic cases of the disease.?? This strongly suggests that both forms of these diseases share common mechanisms and, therefore, genetic animal models are likely to be useful for the development of treatments for all cases of these devastating diseases.

    For more information, visit
    http://neuroscience.nih.gov/Lab.asp?Org_ID=436

    WALS

    Neurodegeneration: Too Much of a Good Thing Kills You

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  • Site-specific Metastasis Genes and Functions (NIH-Only)
    • - Massagu챕, Joan.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : NCI CCR Grand Rounds (NIH Only)

    Site-specific Metastasis Genes and Functions (NIH-Only)

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  • Beyond the Double Helix: Reading and Writing the Histone Code
    • - C. David Allis, Ph.D., Rockefeller University (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    Special Tuesday WALS Lecture

    For more information, visit
    http://www.rockefeller.edu/labheads/allis/allis-lab.php

    The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Beyond the Double Helix: Reading and Writing the Histone Code

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  • TRACO: Vaccines and Translational Research
    • - Schiller, John T.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : TRACO

    TRACO: Vaccines and Translational Research

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  • High Resolution Imaging of the Retina in Vivo with Adaptive Optics
    • - Williams, David R.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Neuroscience

    High Resolution Imaging of the Retina in Vivo with Adaptive Optics

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  • Location Proteomics: A Systems Biology Approach to Subcellular Location
    • - Murphy, Robert F.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Proteomics

    Location Proteomics: A Systems Biology Approach to Subcellular Location

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  • Evasion of Innate Host Defense by Bacterial Pathogens
    • - Frank Deleo, Ph.D., NIAID (2010/03/04)
    • - Category : NIH Director's Seminars
    NIH Director's Seminar Series

    For more information, visit
    2005-2006 Director's Seminar Series

    Evasion of Innate Host Defense by Bacterial Pathogens

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  • Technical Grant Writing workshop for CTSA
    • - NCRR (2010/03/04)
    • - Category : Special

    Technical Grant Writing workshop for CTSA

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  • T Cells and MHC
    • - Philippa Marrack, National Jewish Medical and Research Center (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    It has long been known that T cells are obsessed with MHC proteins. Although we can suggest reasons WHY this might be so, it has been more difficult to find out HOW the obsession occurs. We have recently found a collection of T cell receptors which is even more interested in MHC proteins than the norm. Some of these receptors react with almost any kind of MHC protein with which they are confronted. We have studied these receptors and now suggest a mechanism which allows them to be so promiscuous.

    For more information, visit
    http://www.hhmi.org/research/investigators/marrack.html

    The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    T Cells and MHC

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  • Repair & Mutagenesis of Triplex Targeted Interstrand Crosslinks
    • - Dr. Michael Seidman, NIA (2010/03/04)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group

    Repair & Mutagenesis of Triplex Targeted Interstrand Crosslinks

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  • Journey Matters: Ribonucleoprotein Partnerships Regulating Mrna Transport, Turnover and Translation
    • - Myriam Gorospe, Ph.D., Laboratory of Cellular and Molecular Biology, NIA (2010/03/04)
    • - Category : NIH Director's Seminars
    NIH Director's Seminar Series

    For more information, visit
    2004-2005 Director's Seminar Series

    Journey Matters: Ribonucleoprotein Partnerships Regulating Mrna Transport, Turnover and Translation

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  • Environmental Genomics: a Key to Understanding Human Disease
    • - Schwartz, David A.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Special

    Environmental Genomics: a Key to Understanding Human Disease

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