KOSEN 한인과학기술자네트워크

아래의 자료는 산업기술정보원(http://www.kiniti.re.kr)을 통해 검색된 자료입니다. 웹을 통해 원문신청이 가능합니다. 한글 번역판은 많질 않습니다. * 醫藥品 製造設計 및 操作分析 의 最適化 에 관한 硏究, 김용배, 學位論총(自然科學篇) 1(′78.6):37-48 * 의약품 ( 고형 제제 ) 의 설계와 제조 방법, Yasumura,M., 粉體工學會誌 (JPN) 33(10); P812-818; 1996 * Structure-based drug design, Blundell, Tom L., Nature v 384 n Suppl, p 23-26, 1996, Abstract : The three-dimensional structures of more than 4,000 macromolecules have already been solved, and the number will continue to increase steadily. Many of these macromolecules are important drug targets and it is now possible to use the knowledge of their three-dimensional structure as a good basis for drug design. * Role of shape analysis in drug design, Mezey, Paul G., Images of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 6 Proceedings of the Annual Conference on Engineering in Medicine and Biology v 11 pt 6, p 1905-1906, 1989, 4 Abstract: In drug design the analysis of the shapes of three-dimensional molecular bodies, as opposed to the more conventional study of the molecular skeletons of formal bond systems, provides important insight and a more realistic approach to modeling biochemical interactions. A family of computer techniques is described that are aimed at a nonvisual, numerical characterization and classification of molecular shapes and take into account the conformational nonrigidity of drug molecules. Novel developments include the shape characterization of conformationally flexible molecules, using the dynamic shape code technique. * Computer-assisted drug design and selection, Kaminski, James J.,Advanced Drug Delivery Reviews v 14 n 2-3, p 331-337, 1994, 20 Abstract : Comparative molecular field analysis (CoMFA), a promising new statistical and graphic three-dimensional quantitative structure-activity relationship (3D-QSAR) technique, and its potential in the drug discovery and design process are reviewed. CoMFA, a computer-assisted 3D-QSAR analysis tool, attempts to correlate molecular shape descriptors defined for a set of substrate (drug) molecules with their observed biological activities. 아래의 자료들은 drug design에 관련된 서적들입니다. 대체로 기본서인것으로 판단됩니다. 참고하시기 바랍니다. * The Organic Chemistry of Drug Design and Drug Action, Richard Silverman, Academic Press, 1992 * Drug design, Arins, E. J. Academic Press, 1971 * Textbook of drug design and development, Krogsgaard-Larsen, Povl. Bundgaard, Hans. Harwood Academic Publishers, 1991 >drug design에 대해 잘 설명된 교본을 찾습니다. 가능하면 한글 번역판 이었으면 좋겠습니다.

Below are the additional books (monographs) covering drug design. Drug design. Edited by E. J. Ariens. New York, Academic Press, 1971-<1980>. Series title: Medicinal chemistry ; v. 11. Drug product design and performance / edited by Victor F. Smolen, LuAnn Ball. New York : Wiley, c1984. Series title: Controlled drug bioavailability ; v. 1. Franke, Rainer, 1938- Theoretical drug design methods / by Rainer Franke. Amsterdam ; New York: Elsevier, 1984. Series title: Pharmacochemistry library ; v. 7. Golender, Valerii Efimovich. Logical and combinatorial algorithms for drug design / V.E. Golender and A.B. Rozenblit. Letchworth, Hertfordshire, Eng. : Research Studies Press ; New York : Wiley, c1983. Series title: Chemometrics series ; 6. Martin, Yvonne Connolly, 1936- Quantitative drug design : a critical introduction / Yvonne Connolly Martin. New York : M. Dekker, c1978. Series title: Medicinal research ; v. 8. Molecular modelling and drug design / edited by J.G. Vinter and Mark Gardner. Boca Raton : CRC Press, 1994. Series title: Topics in molecular and structural biology (Boca Raton, Fla.) Rational drug design : novel methodology and practical applications / Abby L. Parrill, M. Rami Reddy, [editors]. Washington, DC : American Chemical Society, c1999. Series title: ACS symposium series 719. Smith and Williams' introduction to the principles of drug design. 2nd ed. / [edited by] H.J. Smith. London ; Boston : Wright, 1988. Smith, H. J. Introduction to the principles of drug design / H.J. Smith, Hywel Williams. Bristol ; Boston : Wright - PSG, 1983.