KOSEN 한인과학기술자네트워크

>칼럼은 어떤 것을 사용하고 분석 조건등을 알려주세요.... 아래의 논문을 참고해 보시기 바랍니다. 1. 2-Methoxy-2-(1-naphthyl)propionic acid, a powerful chiral auxiliary for enantioresolution of alcohols and determination of their absolute configurations by the 1H NMR anisotropy method, Tetrahedron: Asymmetry, Volume 11, Issue 6, 7 April 2000, Pages 1249-1253 Nobuyuki Harada, Masataka Watanabe, Shunsuke Kuwahara, Akinori Sugio, Yusuke Kasai and Akio Ichikawa 2 Determination of l-menthol in pharmaceutical products by high performance liquid chromatography with polarized photometric detection Kouji Hamasakia, Kayoko Katoa, Takaho Watanabea, Yoshihiro Yoshimuraa, Hiroyuki Nakazawaa, *, Atsushi Yamamotob and Akinobu Matsunagab a Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41, Ebara, Shinagawa-ku, Tokyo 142, Japan b Department of Toyama Institute of Health, 17-1, Nakataikoyama, Kosugi-machi, Toyama 939-03, Japan Received 6 February 1997; accepted 3 March 1997. Available online 4 September 1998. Abstract A simple analytical method for l-menthol by high-performance liquid chromatography with a polarized photometric detector was established. The polarized photometric detector was constructed with two polarizers mounted on both sides of the flow cell in a conventional photometric detector and can be easily used for the detection of optically active compound, such as l-menthol. This study was conducted with a newly developed split-cell assembly in order to increase the sensitivity. The characteristic of this method is the ability to determine optically active compounds selectively among the other coexisting materials and the pretreatment of the sample can be very simple or not required at all. The detection of l-menthol by this method is 0.5 g. A good agreement was shown between another commonly used GC method and the method described in this paper. Author Keywords: l-Methanol; Chiral HPLC assay; Polarized photometric detector