KOSEN 한인과학기술자네트워크

>hairless rat 과 nude mouse가 같은 뜻으로 사용되는것인가요?? > hairless mouse 의 종류에는 nude mouse와 fuzzy mouse가 있음 nude mouse-thymus가 제거 되어 T cell이 없어 면역 반응 실험에 사용됨 fuzzy mouse는 일부 부위에 약간의 털이 있고 nude mouse 보다는 튼튼하나 일반 mouse 보다는 알러지에 약함. hairless rat에는 true hairless rat(thymus가 없어 면역 반응실험에 응용) 와 patchwork hairless rat( 약간의 털이 있고,ture hairless 보다 튼튼) 이 있습니다. rat이 mouse 보다 크죠 혹 도움이 되었기를 바랍니다. http://www.angelfire.com/realm2/lex_exotics/Ahairlessrodents.html 참조 Rats and Mice RATS There are two basic types of hairless rats, true hairless and 'patchwork' hairless. True hairless rats have no fur at all on their bodies and usually no whiskers either. Sometimes they have fur as pups which falls out by the time they are 2-3 months old. There are many different genetic strains of true hairless, most if not all of which have come from laboratories, where they are used extensively for medical research. They are missing a part of their immune system called the thymus, which makes them susceptible to disease and allergies. Depending on which strain they are they can be prone to tumors, eye and respiratory infections, heart or kidney disease, diabetes or skin problems. The average lifespan of true hairless rats is 9-18 months old. As it is impossible to tell what strain a true hairless rat is without genetic testing, it is important to obtain true hairless rats from reputable breeders who can provide a pedigree. Breeders are working on stronger stains of true hairless rats through out-crossing with healthy furred rats. Hairless females with few exceptions do not make good breeders. They generally do not lactate at all or enough to support a litter, and cannibalism or abandonment is common. To produce true hairless pups, breeders will mate a hairless male (homozygous) to a furred hairless carrier female (heterozygous for hairless). Half of the offspring produced should be hairless, the other half will be furred hairless carriers. Patchwork hairless rats maintain a certain amount of short, soft fur on their bodies and patches where they are bald. The fur will periodically fall out and grow back in throughout the rat's life in different patterns. They usually maintain whiskers though they are generally brittle and curly. While they are more prone to allergies, they are hardier than the true hairless rats and should live an average lifespan. The females also have no problems reproducing or raising litters. There are three strains of patchwork hairless rats: 1) Double rex: produced from two rex-coated parents (ReRe). Different from the other two strains as they tend to keep some fur on the face, head, feet and ankles while maintaining a mostly hairless body. If bred to a normal-coated rat they will produce rex-coated pups. If bred to a rex or velveteen-coated rat they will produce double rex pups. 2) Double Velveteen: produced from two velveteen-coated parents (CuCu). If bred with a normal-coated rat will produce velveteen-coated pups. If bred to a velveteen or rex-coated rat they will produce double velveteen pups. 3) Double velveteen/Double rex: produced from one double rex-coated parent and one double velveteen-coated parent (CuCuReRe). If bred to a normal-coated rat they will produce rex-coated and/or velveteen-coated pups. Caring for a true or patchwork hairless rat is very similar to a furred rat. With less fur they need to maintain a higher body temperature which quickens their metabolism. They will eat and drink more than furred rats, and should be given some extra protein in their diets. A multi-vitamin formulated for rats can also be put into ther drinking water once a week. To help them stay warm a heating pad on LOW can be place under one third of their cage floor (make sure wires are out of range). Rats are social and should have a companion, but with true hairless rats I suggest keeping hairless with hairless as they will be more gentle with each other. Hairless rats can get scratched easily, and these should be tended to quickly with a safe topical cream. To further prevent scratches, use toys with no sharp edges, make sure hideaways have ample entry and exit space and that cages are coated wire, not just metal. Use a soft bedding instead of woodchips or corn cob which can irritate and itch. There are many on the market made from recycled newspaper, etc. Try to keep hairless rats away from other pets and put an air filter in the room to cut down on the chances of them developing allergies. It is very important to make sure the cage is clean and dry. Never keep your hairless rats by a window or in direct sunlight as they sun-burn easily. MICE There are two main types of hairless mice, nude mice and fuzzy mice. Nude mice are more commonly found than the fuzzy variety. They have no fur at all and usually have no whiskers. The claws need to be clipped more often as they grow very quickly in some strains. They originate from laboratories where they have been used extensively in medical research since the late 1920's. Like hairless rats, they are also missing the part of their immune system called the thymus, making them very susceptible to disease and allergies. There are many different strains of nude mice, some of which are prone to a variety of ailments including neurological problems and diseases of the major organs. Even under laboratory conditions, nude mice usually do not live an average lifespan. Most of the nude mice in the pet trade are laboratory surplus animals distributed to brokers and pet stores. Unfortunately with their compromised immune systems, these mice tend to pick up illnesses and not survive very long. Try to purchase nude mice from a reputable breeder which can give you a pedigree. Some breeders have succeeded in producing stronger nude bloodlines more suitable as pets. Nude female mice tend to not be good breeders, as they produce small litters and have a very short span of fertility (between 2.5 months to 7 months old). They sometimes do not lactate at all or enough to raise their litters, and abandonment or cannibalism is common. Nude mice should be bred by breeding a nude male (homozygous) to a furred nude carrier female (heterozygous for nude). Half of the pups produced will be nude and the other half will be furred nude carriers. Fuzzy mice are more difficult to find as only a handful of breeders have them. There are a few strains of fuzzy mice but they generally have a fine covering of short soft fur which may fall out and grow back in periodically in different patterns. They may or may not have whiskers. Some are mostly bald with patches of fur on the head, shoulders and/or feet. The fuzzy mouse strains seem to be hardier than the nudes, although still more prone to allergies than regular mice. Whether nude or fuzzy, hairless mice have higher metabolisms to help keep themselves warm. Extra protein should be added into their diets, and a multi-vitamin formulated for mice can be put into their water once a week. To help prevent scratches, it is best to keep hairless mice in an aquarium with a mesh screen lid. Toys should not have pointed aspects and hideaways should have ample exit and entry space. Avoid using woodchips as bedding, instead use a soft alternative bedding. It is very important to keep the cage clean, warm and dry. A heating pad on LOW under one third of the tank will help with warmth. An air filter in the room your mice are kept in will also help prevent allergies. Do not keep hairless mice near a window or in direct sunlight, as they are very vulnerable to sunburn.