KOSEN 한인과학기술자네트워크

구글에서 퍼왔습니다. 참고하시기 바랍니다. 요약을 한다면 디쉬에 붙는데는 다양한 물질들이 관여하며 세포 종류에 따라서 더욱 다양합니다. 하지만 대부분 단백질이죠. 그래서 트립신을 사용하시면 가수분해가 일어나서 단백질이 깨져서 떨어지게 됩니다. 셀들의 종류에 따라서 다르지만, 어떤 세포들은 아주 예민해서 트립신에 의해서 죽는수도 있고, 어떤 세포들은 아주 강해서 꿈쩍도 안하는 경우가 있습니다. 상황에 따라서 희석시켜 사용하거나, 다른 물질들을 사용해서 떼는 경우도 있습니다. Cell adhesion molecules involved in the process are first hydrolyzed by extracellular enzymes. Cell adhesion is directly related to protein absorption. Eukaryotes Eukaryotic protozoans express multiple adhesion molecules. An example of a pathogenic protozoan is the malarial parasite (Plasmodium falciparum), which uses one adhesion molecule called the circumsporozoite protein to bind to liver cells, and another adhesion molecule called the merozoite surface protein to bind red blood cells. In human cells, which have many different types of adhesion molecules, the major classes are named integrins, Ig superfamily members, cadherins, and selectins. Each of these adhesion molecules has a different function and recognizes different ligands. Defects in cell adhesion are usually attributable to defects in expression of adhesion molecules. Prokaryotes Prokaryotes have adhesion molecules usually termed "adhesins". Adhesins may occur on pili (fimbriae), flagellae, or the cell surface. Adhesion of bacteria is the first step in colonization and regulates tropism (tissue- or cell-specific interactions). Viruses Viruses also have adhesion molecules required for viral binding to host cells. For example, influenza virus has a hemagglutinin on its surface that is required for recognition of the sugar sialic acid on host cell surface molecules. HIV has an adhesion molecule termed gp120 that binds to its ligand CD4, which is expressed on lymphocytes.