KOSEN 한인과학기술자네트워크

연구논문

• 1. Ji Young Kim , Dong Hee Kim, Hyung Gyun Kim, Gyu-Yong Song, Young Chul Chung, Seong Hwan Roh, Hye Gwang Jeong, Inhibition of tumor necrosis factor-a-induced expression of adhesion molecules in human endothelial cells by the saponins derived from roots of Platycodon grandiflorum, Toxicology and Applied Pharmacology, 2005, in press
  2. Lee SJ, Sakurai H, Koizumi K, Song GY, Bae YS, Kim HM, Kang KS, Surh YJ, Saiki I, Kim SH.MAPK regulation and caspase activation are required in DMNQ S-52 induced apoptosis in Lewis lung carcinoma cells, Cancer Lett. 2005, in press
  3. Seong-Cheol Bang, Ji-Hyun Lee, Gyu-Yong Song, Dong-Hee Kim, Mi-Young Yoon and Byung-Zun Ahn, Antitumor Activity of Pulsatilla koreana Saponins and Their Structure?Activity Relationship, CHEMICAL & PHARMACEUTICAL BULLETIN, 2005, 53(11), 1451
  4. Park EM, Joh TH, Volpe BT, Chu CK, Song G, Cho S, A neuroprotective role of extracellular signal-regulated kinase in N-acetyl-O-methyldopamine-treated hippocampal neurons after exposure to in vitro and in vivo ischemia, Neuroscience. 2004;123(1):147-54
  5. Lee EO, Kwon BM, Song GY, Chae CH, Kim HM, Shim IS, Ahn KS, Kim SH. Heyneanol A induces apoptosis via cytochrome c release and caspase activation in human leukemic U937 cells, Life Sci. 2004, 74(18):2313-26
  6. Park EM, Lee IJ, Kim SH, Song GY, Park YM.. Inhibitory effect of a naphthazarin derivative, S64, on heat shock factor (Hsf) activation and glutathione status following hypoxia. Cell Biol Toxicol. 2003, 19(5), 273-84.
  7. Kang IC, Kim SA, Song GY, Baek NI, Park YD, Ryu SY, Saiki I, Kim SH. Effects of the ethyl acetate fraction of Spatholobi caulis on tumour cell aggregation and migration. Phytother Res. 17(2), 163-7 (2003)
  8. Gumina G, Chong Y, Choo H, Song GY, Chu CK, L-nucleosides: antiviral activity and molecular mechanism. Curr Top Med Chem. 2002 Oct;2(10):1065-86
  9. Song GY, Naguib FN, el Kouni MH, Chu CK. Synthesis of carbocyclic orotidine analogs as potential orotidine decarboxylase inhibitors. Nucleosides Nucleotides Nucleic Acids. 2001, 20(12):1915-25.
  10. Song GY, Paul V, Choo H, Morrey J, Sidwell RW, Schinazi RF, Chu CK, Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus. J Med Chem. 2001, 44(23):3985-93.
  11. Gumina G, Song GY, Chu CK. Advances in antiviral agents for hepatitis B virus. Antivir Chem Chemother. 2001;12 Suppl 1:93-117
  12. Kim SH, Kang IC, Yoon TJ, Park YM, Kang KS, Song GY, Ahn BZ. Antitumor activities of a newly synthesized shikonin derivative, 2-hyim-DMNQ-S-33. Cancer Lett. 2001, 172(2):171-5.
  13. Gumina G, Song GY, Chu CK. L-Nucleosides as chemotherapeutic agents. FEMS Microbiol Lett. 2001, 202(1):9-15
  14. Chun BK, Song GY, Chu CK. Stereocontrolled syntheses of carbocyclic C-nucleosides and related compounds. J Org Chem. 2001, 66(14):4852-8.
  15. Cho S, Kim Y, Cruz MO, Park EM, Chu CK, Song GY, Joh TH. Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: protein kinase A-dependent mechanism. Glia. 2001, 33(4):324-33.
  16. You YJ, Kim Y, Song GY, Ahn BZ. (E)-6-(1-alkyloxyiminoalkyl)-5,8-dimethoxy-1,4- naphthoquinones: synthesis, cytotoxic activity and antitumor activity. Bioorg Med Chem Lett. 2000, 10(20):2301-3.
  17. Tam MN, Nam NH, Jin GZ, Song GY, Ahn BZ. Synthesis and evaluation of the antitumor activity of 2-substituted 1,4-dihydroxy-9,10-anthraquinones. Arch Pharm (Weinheim). 2000, 333(6):189-94
  18. Song GY, Kim Y, You YJ, Cho H, Kim SH, Sok DE, Ahn BZ. Naphthazarin derivatives (VI): synthesis, inhibitory effect on DNA topoisomerase-I and antiproliferative activity of 2- or 6-(1-oxyiminoalkyl)-5,8-dimethoxy-1,4-naphthoquinones. Arch Pharm (Weinheim). 2000, 333(4):87-92
  19. Song GY, Kim Y, Zheng XG, You YJ, Cho H, Chung JH, Sok DE, Ahn BZ. Naphthazarin derivatives (IV): synthesis, inhibition of DNA topoisomerase I and cytotoxicity of 2- or 6-acyl-5,8-dimethoxy-1, 4-naphthoquinones. Eur J Med Chem. 2000, 35(3):291-8.

특허

• 발명의 명칭 : 신경세포 보호활성을 갖는 산삼 추출정제액을 함유하는 조성물
  ,특허등록번호 : 10-2004-0055086
  
  발명의 명칭 : 항암 활성을 갖는 산삼 추출정제액을 정제하는 방법 및 이를 함유하는 조성물, 특허등록번호 : 10-2004-0055088
  
  발명의 명칭 : 암세포 증식억제 효과를 나타내는 광물석분 특허등록번호 : 10-2003-0029121