Marine Drug Discovery
Research Interests
Natural Products Chemistry of Marine Organisms
Organic Synthesis & Medicinal Chemistry of Bioactive Molecules
Understanding of Metabolic Disorders and Physical Endurance
Chemical Genomic Study of Nuclear Receptors
Discovery and development of bioactive molecules from marine organisms
In our laboratory, we use underwater diving equipment(SCUBA) to directly enter the sea and observe the marine ecosystem, and isolate and identify various invertebrates and microorganisms that coexist and parasitize them. In addition, grab samplers are used to collect sediment from coastal areas, and microorganisms are isolated and identified in tidal flats. These microorganisms are cultured in a medium containing seawater, extracted with an organic solvent, and purified by a variety of chromatographic methods. The purified molecule has a chemical structure determined by nuclear magnetic resonance(NMR) and mass spectrometer(MS). Also, we screen the biological activity of the purified molecules through a variety of experimental methods.
국가
대한민국
소속기관
서울대학교 (학교)
연락처
책임자
강헌중 hjkang@snu.ac.kr