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Research Interest
Our main research goal is to identify new molecular targets for drug discovery in autoimmune and chronic inflammatory disease areas. To elucidate novel functions and regulatory mechanisms of immune-modulating proteins, we are using a wide array of biochemical and cell biological approaches as well as mouse models. In addition, we are studying the interrelationship between the host immune system and the commensal microbiota and its influences on the metabolic diseases, rheumatoid arthritis, and cancer.Recent Publications
1. Gut-specific delivery of Th17 cells reduces obesity and insulin resistance in mice (2017) Gastroenterology 152:1998-2010
2. SH2 domains serve as lipid binding modules for p-Tyr signaling molecules (2016) Molecular Cell 62:7-20
3. Lipids regulate Lck protein activity through their interaction with the Lck Src homology domain (2016) J Biol Chem 291:17639-50
4. TLR9 regulates adipose tissue inflammation and obesity-related metabolic disorders (2015) Obesity 23:2199-206
5. UNC93B1 is essential for the plasma membrane localization and signaling of TLR5 (2014) PNAS 111:7072-7
국가
대한민국
소속기관
한국과학기술원 (학교)
연락처
042-350-4861 https://gsmse.kaist.ac.kr/professor01
책임자
김유미 youmekim@kaist.ac.kr