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  • NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Academic Research Skills for Physician Scientists:?? From the Outer Banks to the Singapore Straits
    • - Keith M. Sullivan, MD James B. Wyngaarden Professor of Medicine Division of Cellular Therapy, Duke University Medical Center (2017/07/20)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Academic Research Skills for Physician Scientists: From the Outer Banks to the Singapore Straits

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Academic Research Skills for Physician Scientists:?? From the Outer Banks to the Singapore Straits

  • NIH VideoCast - Clinical Center Research Hospital Board Meeting - July 2017
    • - Office of the Director, NIH (2017/07/18)
    • - Category : Advisory Board Meetings and Workshops
    Clinical Center Advisory Board Meeting

    For more information go to https://ccrhb.od.nih.gov/

    NIH VideoCast - Clinical Center Research Hospital Board Meeting - July 2017

  • NIH VideoCast - NIH Citizen Science Symposium
    • - Citizen Science Working Group, NIH (2017/07/18)
    • - Category : Conferences
    Citizen Science is a collaborative approach to research involving the public, not just as subjects of the research or advisors to the research but as direct collaborators and partners in the research process itself. The purpose of this workshop is to inform and engage NIH employees and contractors in discussions on how citizen science and crowdsourcing can enrich and further research as a complementary method, and to energize the local citizen science community.

    NIH VideoCast - NIH Citizen Science Symposium

  • NIH VideoCast - Hematopoietic Stem Cells Aging ??? Mechanisms, Consequences and Interventions
    • - Dr. Emmanuelle Passegu??, Professor, Department of Genetics and Development, Columbia University Medical Center, Director, Columbia Stem Cell Initiative (CSCI), New York (2017/07/16)
    • - Category : Geroscience
    The Trans-NIH GeroScience Interest Group (GSIG), cordially invites you to its summer seminar, featuring Dr. Emmanuelle Passegu??. Dr. Passegue is a Professor in the Department of Genetics and Development at the Columbia University Medical Center and Director of the Columbia Stem Cell Initiative (CSCI) in New York. She is widely recognized for her expertise on hematopoietic stem cell (HSC) biology. Her research over the past 10-years has focused on understanding the cellular and molecular processes controlling HSC activity during homeostasis, and addressing how these regulations are changed in myeloid malignancies and physiological aging. Her laboratory employs a variety of cross-disciplinary approaches using mouse models and human patient samples to identify genetic and/or molecular pathways as therapeutic targets to treat human diseases. Current projects investigate the role of apoptosis, autophagy, immune regulations, DNA repair mechanisms, and changes in the bone marrow niche microenvironment in HSC function in normal, stress, leukemic and aging conditions.

    The GSIG was created to discuss and explore the complex relationships between the biology of aging and the biology of diseases and conditions that are of interest to various institutes and centers across the NIH.

    For more information go to http://sigs.nih.gov/geroscience/Pages/default.aspx

    NIH VideoCast - Hematopoietic Stem Cells Aging ??? Mechanisms, Consequences and Interventions

  • NIH VideoCast - Special Event: Celebrating Images of America: US National Library of Medicine
    • - Jeffrey Reznick, Chief, History of Medicine Division, NLM, NIH (2017/07/16)
    • - Category : History of Medicine
    The National Library of Medicine (NLM) is proud to announce the forthcoming publication, on June 26, 2017, of a new, illustrated history of its development, from the early 19th century through the late 20th century. Co-edited by Jeffrey S. Reznick, PhD, and Kenneth M. Koyle, chief and deputy chief of the NLM History of Medicine Division, and incorporating the research, writing, and technical expertise of staff from across the Library, this new book appears in the popular series Images of America, by Arcadia Publishing. A hardback version of the book is available from booksellers, and an electronic version of the complete book, including the 170+ black-and-white images which appear in it, will be freely available via NLM Digital Collections beginning June 26.

    Many individuals have written about the National Library of Medicine and its origins as the Library of the Office of the U.S. Army Surgeon General. However, this book is unlike previous publications because it introduces the history of the Library primarily through images from its own rich collections, along with a handful of other images from the collections of the National Archives, the National Museum of Health and Medicine, the Smithsonian Institution Archives, and the Rudolph Matas Library of the Health Sciences at Tulane University. The book reveals the work of generations of visionary leaders and dedicated individuals who experienced the American Civil War, the world wars, the Cold War, and the dawn of the Information Age. This forum will feature contributors to the book who will speak on how the book was envisioned and produced with an eye to creating an accessible and engaging public history of the NLM.

    For more information go to https://www.nlm.nih.gov/hmd/happening/lectures/lectures_2017.html

    NIH VideoCast - Special Event: Celebrating Images of America: US National Library of Medicine

  • NIH VideoCast - NCI Clinical Trials and Translational Research Advisory Committee (CTAC) - July 2017
    • - NCI, NIH (2017/07/15)
    • - Category : Clinical Trials and Translational Research
    The CTAC makes recommendations on the NCI-supported national clinical trials enterprise to build a strong scientific infrastructure by bringing together a broadly developed and engaged coalition of stakeholders involved in the clinical trial process.

    For more information go to http://deainfo.nci.nih.gov/advisory/ctac/ctacmeetings.htm

    NIH VideoCast - NCI Clinical Trials and Translational Research Advisory Committee (CTAC) - July 2017

  • NIH VideoCast - Psychiatric Genomics in the Era of Team Science Symposium
    • - Office of Genomics Research Coordination, National Institute of Mental Health, NIH (2017/07/14)
    • - Category : Special
    The last decade has seen unprecedented progress in Psychiatric Genomics and for the first-time real advances have been made in delineating the genetic architecture of neuropsychiatric disorders and their underlying molecular pathophysiology. This progress has been facilitated by a convergence in the understanding of the structure and function of the human genome; the development of high throughput sequencing technologies that can be deployed across molecular scales (e.g. DNA, RNA, methylation etc.) and the creation of large bio- and data- repositories. In parallel, the team science (TS) approach has been refined as a novel mechanism to create global large scale ???collaboratories??? that can efficiently and rapidly integrate samples, pipelines, data and brainpower to work on some of the hard problems in Neuropsychiatry. This symposium will provide a review of the state of the art in the field of Neuropsychiatric Genomics across the genomic landscape including gene discovery and regulation, causal/probabilistic modeling of disease states including functional follow up and behavioral and clinical outcomes. The use of rare genetic disorders as models of disease will be discussed. Results will be presented from Caucasian and non-Caucasian populations, including ancestral African population samples. The utility and the challenges of using large scale well curated brain banks and bio- and data- repositories will be highlighted. A focus of the symposium will be to explore the integrative and synergistic nature of these efforts, the inherent opportunities for advancing the field and to lay out a vision for the future of Neuropsychiatric Genomics.

    NIH VideoCast - Psychiatric Genomics in the Era of Team Science Symposium

  • NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Physician Wellbeing:?? Challenges and Opportunities
    • - Carol A. Bernstein, MD Associate Professor of Psychiatry Vice Chair for Education and Director of Residency Training New York University School of Medicine and Past President, American Psychiatric Association (2017/07/14)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Physician Wellbeing: Challenges and Opportunities

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    NIH VideoCast - CC Grand Rounds: Contemporary Issues in Graduate Medical Education: Physician Wellbeing:?? Challenges and Opportunities

  • NIH VideoCast - Special Event: Celebrating 20 Years of Harry Potter, Part 2
    • - Jeffrey Reznick, Chief, History of Medicine Division, NLM, NIH (2017/07/11)
    • - Category : History of Medicine
    Monsters in the Stacks: How Harry Potter Came to NLM

    Stephen Greenberg, PhD, Head, Rare Books & Early Manuscripts, NLM History of Medicine Division

    Join us to learn how staff at the National Library of Medicine became inspired to undertake an exhibition about Harry Potter, drawing on collections of the Library, including works by real historical figures such as the alchemist Nicholas Flamel, who is a key figure in the first Harry Potter novel; the naturalist Conrad Gesner, who wrote about dragons and unicorns; and the mystic and toxicologist Paracelsus, whose potions and prophecies would have made him an excellent addition to the Hogwarts faculty. As part of a week-long celebration of the 20th anniversary of the publication of Harry Potter and the Philosopher???s Stone, the National Library of Medicine presents two special lectures. The celebration will also include a special display of the 15th, 16th, and 17th century books that influenced the Harry Potter series along with the six-banner traveling exhibition, Harry Potter???s World: Renaissance Science, Magic, and Medicine. Visit this special exhibition in the History of Medicine Reading Room, June 26 ??? 30, 2017.

    For more information go to https://www.nlm.nih.gov/hmd/happening/lectures/lectures_2017.html

    NIH VideoCast - Special Event: Celebrating 20 Years of Harry Potter, Part 2

  • NIH VideoCast - CC Grand Rounds: 1) Reassessing the Management of Sepsis and Septic Shock and 2) Surviving Sepsis: By Draining the Swamps?
    • - 1) Anthony F. Suffredini, MD Deputy Chief, Senior Investigator, Critical Care Medicine Department, CC, NIH and 2) Robert S. Munford, MD, MA Senior Clinician and Acting Chief, Laboratory of Clinical Infectious Diseases and Chief, Antibacterial Host Defense Section, NIAID, NIH (2017/06/30)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: 1) Reassessing the Management of Sepsis and Septic Shock and 2) Surviving Sepsis: By Draining the Swamps?

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    NIH VideoCast - CC Grand Rounds: 1) Reassessing the Management of Sepsis and Septic Shock and 2) Surviving Sepsis: By Draining the Swamps?

  • NIH VideoCast - 2017 PRIDE - Making Our Stories Count
    • - JoAnne Keatley, Elliot Kennedy, Mahri Monson, Phil Crehan, Alexandra Chandler (2017/06/30)
    • - Category : Diversity
    A panel discussion on better understanding and quantifying Lesbian Gay Bisexual Transgender (LGBT) data in the federal workforce. Hear experts from NIH, HHS, EPA, World Bank, and the Intelligence community weigh in on understanding and quantifying LGBT data in the federal workforce and beyond. This discussion will create a better understanding of the NIH workforce, as we ???continue towards our goal of fostering an environment where diverse talent is leveraged to advance health discovery.???

    For more information go to https://www.edi.nih.gov/people/sep/lgbti/about

    NIH VideoCast - 2017 PRIDE - Making Our Stories Count

  • NIH VideoCast - From microbial immunity to genome editing
    • - Feng Zhang, Ph.D., Core Member, The Broad Institute of MIT; Investigator, McGovern Institute for Brain Research; Associate Professor, Departments of Brain and Cognitive Sciences and Biological Engineering, Massachusetts Institute of Technology (2017/06/30)
    • - Category : WALS - Wednesday Afternoon Lectures
    NIH Director`s Wednesday Afternoon Lecture Series

    The microbial CRISPR-Cas adaptive immune systems provide archaea and bacteria with a programmable defense against invading nucleic acids. Several years ago, Dr. Zhang and others reported that the effector module from Streptococcus pyogenes CRISPR-Cas9 (SpCas9) could be harnessed for genome editing. Following this work, Zhang`s lab has discovered, characterized, and engineered additional Cas enyzmes for use as molecular biology tools. These include a novel class of CRISPR-Cas systems that use RNA-guided RNases, such as Cas13a (C2c2) and Cas13b. Leveraging the natural properties of Cas13a, the lab developed a single-molecule nucleic acid sensing platform termed SHERLOCK, which can be used for rapid pathogen detection and genotyping. Zhang is continuing to explore microbial diversity to identify novel enzymes and systems that could serve as the basis for the development of additional molecular biology tools and applying these tools to tackle complex biological questions..

    For more information go to https://oir.nih.gov/wals

    NIH VideoCast - From microbial immunity to genome editing

  • NIH VideoCast - Law of STAT fives, root orchestrators of lymphocyte homeostasis and function
    • - Alejandro Villarino, Phd., NIAMS, NIH (2017/06/30)
    • - Category : Immunology
    Immunology Interest Group Seminar Series

    The transcription factor STAT5 is fundamental to the mammalian immune system. Operating downstream of cytokines and growth factors, it impacts all aspects of lymphocyte biology, from general cellular processes like proliferation and apoptosis, to specialized immunological programs like effector and regulatory T cell differentiation. Genetic studies in humans underscore its widespread influence as mutations of STAT5 or upstream activators manifest varied Alejandro Villarino, NIAMS, NIHimmunological phenotypes including immunodeficiency, autoimmunity and hematological malignancies. Mouse models of STAT5 deficiency have affirmed these findings and have been instrumental in defining its broad homeostatic and metabolic functions, as well as lineage-restricted pro- and anti-inflammatory capabilities. Coupled to high-throughput sequencing technologies, they have also enabled genome-wide discovery of STAT5-dependent gene networks in both innate and adaptive lymphocytes, and have yielded valuable mechanistic insights on how it instructs gene transcription. Ongoing research will further clarify how STAT5 works at cellular, molecular and genomic levels with the overarching goal of informing the development of therapeutic agents to target STAT5 and/or relevant downstream targets.

    Alejandro Villarino is a post-doctoral research fellow in the laboratory of John O???Shea in NIAMS. His interest in cytokines began as a graduate student in Chris Hunter???s laboratory at the University of Pennsylvania when he first encountered the double-edged nature of infection-induced cytokine responses. That dichotomy was the theme of his dissertation on interleukin-27, a cytokine that was initially classified as pro-inflammatory but which he discovered has critical anti-inflammatory properties that have since been observed in numerous disease settings. Following a string of highly cited publications, he transitioned to postdoctoral research in Abul Abbas??? lab at the University of California San Francisco where he studied cell intrinsic mechanisms regulating lymphocyte cytokine production in the context of autoimmune disease. This was also a prolific period, both in terms of scientific growth and publication output, that afforded him the opportunity to mentor several junior lab members, among them a research assistant whose work culminated in a peer reviewed article where he is credited as senior author. Since joining the National Institute of Arthritis and Musculoskeletal and Skin Diseases, Alejandro have embraced next-generation sequencing as a means of interrogating cytokine signaling. His work here has focused on cytokines operating via STAT5, a central transcription factor in lymphocyte biology and increasingly relevant drug target for autoimmune and metastatic disease. Using a combination of genetic and genomic approaches, he has addressed the long-standing question of whether STAT5A and STAT5B, the two mammalian STAT5 paralogs, are redundant or functionally distinct. He has also defined cellular and molecular functions for STAT5 across innate and adaptive lymphocyte lineages, identified important STAT5-containing transcription factor networks, and uncovered a key role for STAT5 in metabolic programming of immune cells. This work has yielded valuable insights on how STAT5 impacts lymphocyte biology, many of which are relevant for other STATs and transcription factors, and has empowered him with the skill sets necessary to design, execute and analyze genome- and transcriptome-level experiments involving small numbers of primary immune cells and multiple variables (i.e. different genotypes, cell populations, cytokine treatments).

    NIH VideoCast - Law of STAT fives, root orchestrators of lymphocyte homeostasis and function

  • NIH VideoCast - Celebrating 21 Years of the CURE Program
    • - Center to Reduce Cancer Health Disparities, National Cancer Institute, NIH (2017/06/29)
    • - Category : Conferences
    The National Cancer Institute???s (NCI???s) Center to Reduce Cancer Health Disparities (CRCHD) will host the "Celebrating 21 Years of the Continuing Umbrella of Research Experiences (CURE) Program" on June 27, 2017, at the NIH Natcher Conference Center on the NIH Bethesda campus.

    The celebration will recognize an exemplary group of current and former CURE scholars, mentors, and champions, with opening addresses by NCI and CURE leadership. Honorees include CURE scholars from the very earliest stages of the CURE pipeline to those who have made a significant impact in the fields of cancer and cancer health disparities research, as well as mentors and champions who are vital to CURE???s success.

    For more information go to http://www.cancermeetings.org/PDW2017

    NIH VideoCast - Celebrating 21 Years of the CURE Program

  • NIH VideoCast - Summer Lecture Series 1 - How Do Race and Wealth Affect Your Health? My Personal Story in Science
    • - Eliseo Perez-Stable, MD, Director, National Institute on Minority Health and Disparities, NIH (2017/06/29)
    • - Category : Career Development/OITE
    How Do Race and Wealth Affect Your Health? My Personal Story in Science

    For more information go to https://training.nih.gov

    NIH VideoCast - Summer Lecture Series 1 - How Do Race and Wealth Affect Your Health? My Personal Story in Science

  • NIH VideoCast - Special Event: Celebrating 20 Years of Harry Potter, Part 1
    • - Elizabeth Bland, Curator of the NLM Library???s exhibition Harry Potter???s World and independent writer and illustrator (2017/06/29)
    • - Category : History of Medicine
    A Look into the Pensieve: Reflections on Harry Potter at Twenty Years

    Elizabeth Bland, Curator of the Library???s exhibition Harry Potter???s World and independent writer and illustrator

    On June 26th, 1997, London-based publisher Bloomsbury released Harry Potter and the Philosopher???s Stone, the first novel in the Harry Potter series. Twenty years on, the ever-popular series continues to resonate with new readers. To mark the 20th Anniversary of the Harry Potter series, ???A Look into the Pensieve??? will revisit the Library???s exhibition Harry Potter???s World: Renaissance, Science, Magic, and Medicine, including links between author Rowling???s fictional world and writings featured in the collections of the Library; themes from the series that have continued relevance today; and the works??? impact on a now-adult fandom who matured right alongside The Boy Who Lived. As part of a week-long celebration of the 20th anniversary of the publication of Harry Potter and the Philosopher???s Stone, the National Library of Medicine presents two special lectures. The celebration will also include a special display of the 15th, 16th, and 17th century books that influenced the Harry Potter series along with the six-banner traveling exhibition, Harry Potter???s World: Renaissance Science, Magic, and Medicine. Visit this special exhibition in the History of Medicine Reading Room, June 26 ??? 30, 2017.

    For more information go to https://www.nlm.nih.gov/hmd/happening/lectures/lectures_2017.html

    NIH VideoCast - Special Event: Celebrating 20 Years of Harry Potter, Part 1

  • NIH VideoCast - Responsible Communication of Basic Biomedical Research: Enhancing Awareness and Avoiding Hype
    • - National Institute of General Medical Sciences, NIH (2017/06/24)
    • - Category : Conferences
    Media Workshop

    NIH VideoCast - Responsible Communication of Basic Biomedical Research: Enhancing Awareness and Avoiding Hype

  • NIH VideoCast - Muscular Dystrophy Coordinating Committee (MDCC) Meeting - June 2017
    • - NIH (2017/06/23)
    • - Category : Advisory Board Meetings and Workshops
    The Muscular Dystrophy Community Assistance, Research, and Education Amendments of 2001 ("MD-CARE Act"; P.L. 107-84) authorized the establishment of the Muscular Dystrophy Coordinating Committee (MDCC) to ??????coordinate activities across the National Institutes and with other Federal health programs and activities relating to the various forms of muscular dystrophy.??? The membership of the MDCC includes representatives from various Federal agencies and voluntary health organizations.

    For more information go to https://mdcc.nih.gov/meetings_and_events/index.htm

    NIH VideoCast - Muscular Dystrophy Coordinating Committee (MDCC) Meeting - June 2017

  • NIH VideoCast - NCI Board of Scientific Advisors and the National Cancer Advisory Board - June 2017 (Day 1)
    • - NCI, NIH (2017/06/23)
    • - Category : NCI Board of Scientific Advisors
    The 9th Joint Meeting of the NCI Board of Scientific Advisors and the National Cancer Advisory Board

    NIH VideoCast - NCI Board of Scientific Advisors and the National Cancer Advisory Board - June 2017 (Day 1)

  • NIH VideoCast - NIAMS Advisory Council - June 2017
    • - NIAMS, NIH (2017/06/23)
    • - Category : Advisory Board Meetings and Workshops
    92nd NIAMS Advisory Council

    Stephen I. Katz, M.D., Ph.D., Chair

    For more information go to http://www.niams.nih.gov/About_Us/Committees/council_roster.asp

    NIH VideoCast - NIAMS Advisory Council - June 2017