- 4
이미 젖산은 숫송아지의 거세에 사용되기도 하였습니다.
제가 알고 싶은 것은
1. 제가 테스트할 때는 20% 젖산을 난소에 주사하였습니다. 이에 암소의 난소는 생식능력을 잃었습니다. 이는 도축하여 관찰한 결과입니다.
그런데 80% 젖산을 난소에 주사하였더니 3개월 후에 암소의 난소는 기능을 다시 회복하였다고 합니다. 물론 도축한 결과는 아니고 암소에게 발정이 온 것으로 판단하였습니다.
왜 일까요?
2. 젖산은 20%일 때보다 80% 일때 오히려 산으로서의 효과가 더 높은 것이 아닌가요?
왜 이런 결과가 나왔는지 추론조차 못하고 있습니다.
- 젖산
- 난소
- 거세
각 분야 한인연구자와 현업 전문가분들의 답변을 기다립니다.
-
답변
박종명님의 답변
2017-08-15- 2
답변
1. 젖산을 이용한 화학적 거세는 고농도 젖산으로 생식선 조직에 대한 괴사작용을 일으켜 거세를 일으키는 방법으로 85 ~ 92% 농도의 젖산을 멸균 여과하여 사용하며, 숫소의 거세에 활용된바 있습니다.
2. 질의하신 젖산은 당연히 20% 보다 80% 젖산이 더 강력합니다.
3. 20% 젖산을 암소의 난소에 주사하여 생식능력을 잃었는데, 80% 젖산을 난소에 주사하였더니 3개월 후에 난소의 기능을 회복하였다고 (암소에서 발정이 온 것으로 판단) 함은 젖산을 주사하는 시술상의 문제로 추정됩니다. 동물은 상처를 입으면 그 상처를 다시 회복시키는 (재생력) 성질이 있어서 본래의 상태로 되돌아가려고 합니다.
4. 젖산을 이용한 거세는 숫소에서 고환이 잔존하거나 숫동물로서의 거친 특성을 유지하는 수가 있습니다. 그래서 수술적 방법에 의한 거세의 대안으로 적합하지 않다고 합니다.
박종명(jmhi54) 2017-08-18Aust Vet J. 1989 Sep;66(9):272-6.
An evaluation of calf castration by intra-testicular injection of a lactic acid solution.
Fordyce G1, Hodge PB, Beaman NJ, Laing AR, Campero C, Shepherd RK.
Author information
Abstract
This experiment evaluated intra-testicular injection of a sclerosing drug, lactic acid, for castration of bulls. Its use was compared in 58 Brahman cross calves (50 to 128kg) with the general practice of open surgical castration. Chemical castration appeared to be more painful than surgical castration, though post-operative swelling and pain appeared similar for both methods. Chemical castration took 3 times longer than surgical castration (58 sec v 20 sec; P less than 0.01). Scrotal necrosis occurred in 25% of chemically-castrated calves and appeared due to drug leakage from the testes under the high pressure of injection. Healing time for chemical castrates was approximately twice that for surgical castrates. Five chemically-castrated calves (18%) retained one testis. Though all 5 were rendered sterile, each maintained androgenesis. This led to secondary male behaviour which caused management problems. Castration method did not influence post-operative growth. It is concluded that lactic acid administration is not a suitable alternative to the open surgical technique for castration of Brahman cross calves.
PMID: 2684125
[Indexed for MEDLINE]
박종명(jmhi54) 2017-08-18Aust Vet J. 1989 Sep;66(9):272-6.
An evaluation of calf castration by intra-testicular injection of a lactic acid solution.
Fordyce G1, Hodge PB, Beaman NJ, Laing AR, Campero C, Shepherd RK.
Author information
Abstract
This experiment evaluated intra-testicular injection of a sclerosing drug, lactic acid, for castration of bulls. Its use was compared in 58 Brahman cross calves (50 to 128kg) with the general practice of open surgical castration. Chemical castration appeared to be more painful than surgical castration, though post-operative swelling and pain appeared similar for both methods. Chemical castration took 3 times longer than surgical castration (58 sec v 20 sec; P less than 0.01). Scrotal necrosis occurred in 25% of chemically-castrated calves and appeared due to drug leakage from the testes under the high pressure of injection. Healing time for chemical castrates was approximately twice that for surgical castrates. Five chemically-castrated calves (18%) retained one testis. Though all 5 were rendered sterile, each maintained androgenesis. This led to secondary male behaviour which caused management problems. Castration method did not influence post-operative growth. It is concluded that lactic acid administration is not a suitable alternative to the open surgical technique for castration of Brahman cross calves.
PMID: 2684125
[Indexed for MEDLINE] -
답변
박종명님의 답변
2017-08-18- 2
Aust Vet J. 1989 Sep;66(9):272-6.
An evaluation of calf castration by intra-testicular injection of a lactic acid solution.
Fordyce G1, Hodge PB, Beaman NJ, Laing AR, Campero C, Shepherd RK.
Author information
Abstract
This experiment evaluated intra-testicular injection of a sclerosing drug, lactic acid, for castration of bulls. Its use was compared in 58 Brahman cross calves (50 to 128kg) with the general practice of open surgical castration. Chemical castration appeared to be more painful than surgical castration, though post-operative swelling and pain appeared similar for both methods. Chemical castration took 3 times longer than surgical castration (58 sec v 20 sec; P less than 0.01). Scrotal necrosis occurred in 25% of chemically-castrated calves and appeared due to drug leakage from the testes under the high pressure of injection. Healing time for chemical castrates was approximately twice that for surgical castrates. Five chemically-castrated calves (18%) retained one testis. Though all 5 were rendered sterile, each maintained androgenesis. This led to secondary male behaviour which caused management problems. Castration method did not influence post-operative growth. It is concluded that lactic acid administration is not a suitable alternative to the open surgical technique for castration of Brahman cross calves.
PMID: 2684125
[Indexed for MEDLINE]
-
답변
박종명님의 답변
2017-08-18- 1
Aust Vet J. 1989 Sep;66(9):272-6.
An evaluation of calf castration by intra-testicular injection of a lactic acid solution.
Fordyce G1, Hodge PB, Beaman NJ, Laing AR, Campero C, Shepherd RK.
Author information
Abstract
This experiment evaluated intra-testicular injection of a sclerosing drug, lactic acid, for castration of bulls. Its use was compared in 58 Brahman cross calves (50 to 128kg) with the general practice of open surgical castration. Chemical castration appeared to be more painful than surgical castration, though post-operative swelling and pain appeared similar for both methods. Chemical castration took 3 times longer than surgical castration (58 sec v 20 sec; P less than 0.01). Scrotal necrosis occurred in 25% of chemically-castrated calves and appeared due to drug leakage from the testes under the high pressure of injection. Healing time for chemical castrates was approximately twice that for surgical castrates. Five chemically-castrated calves (18%) retained one testis. Though all 5 were rendered sterile, each maintained androgenesis. This led to secondary male behaviour which caused management problems. Castration method did not influence post-operative growth. It is concluded that lactic acid administration is not a suitable alternative to the open surgical technique for castration of Brahman cross calves.
PMID: 2684125
[Indexed for MEDLINE]
-
답변
박종명님의 답변
2017-08-18- 1
Aust Vet J. 1989 Sep;66(9):272-6.
An evaluation of calf castration by intra-testicular injection of a lactic acid solution.
Fordyce G1, Hodge PB, Beaman NJ, Laing AR, Campero C, Shepherd RK.
Author information
Abstract
This experiment evaluated intra-testicular injection of a sclerosing drug, lactic acid, for castration of bulls. Its use was compared in 58 Brahman cross calves (50 to 128kg) with the general practice of open surgical castration. Chemical castration appeared to be more painful than surgical castration, though post-operative swelling and pain appeared similar for both methods. Chemical castration took 3 times longer than surgical castration (58 sec v 20 sec; P less than 0.01). Scrotal necrosis occurred in 25% of chemically-castrated calves and appeared due to drug leakage from the testes under the high pressure of injection. Healing time for chemical castrates was approximately twice that for surgical castrates. Five chemically-castrated calves (18%) retained one testis. Though all 5 were rendered sterile, each maintained androgenesis. This led to secondary male behaviour which caused management problems. Castration method did not influence post-operative growth. It is concluded that lactic acid administration is not a suitable alternative to the open surgical technique for castration of Brahman cross calves.
PMID: 2684125
[Indexed for MEDLINE]
답변에 감사드립니다.
답변은 받았지만 제가 원하는 수준의 답변이 아니네요. 혹시 대답해주신 것에 대한 참고문헌을 알 수 있을까요? 특히 답변4번은 대한 참고문헌을 부탁해도 될까요?