전체 8345
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- Evolution of Two Adaptive Immune Systems
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- - Max D. Cooper, University of Alabama at Birmingham (2010/03/04)
- - Category : Wednesday Afternoon Lectures
- The adaptive immune system in jawed vertebrates features the generation of diverse T and B cell repertoires of anticipatory receptors through V(D)J rearrangement. We have found that living representatives of the jawless vertebrates, lamprey and hagfish, also generate a very large repertoire of variable lymphocyte receptors (VLR). However, unlike BCR and TCR, the VLR proteins are composed of multiple leucine rich repeats (LRR), a stalk region, and a glycosyl-phosphatityl-inositol anchor that tethers them to the lymphocyte surface. Differences in numbers and sequences of the constituent LRRs account for the VLR diversity. Mature VLR genes are created through a multistep assembly process that involves a random modular insertion of different LRR coding sequences into an incomplete germline VLR gene.
NIH Director's Wednesday Afternoon Lecture Series
Evolution of Two Adaptive Immune Systems
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- Recombinant DNA Advisory Committee (RAC) March 2007
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- - National Institutes of Health (U.S.). Recombinant DNA Advisory Committee. (2010/03/04)
- - Category : Advisory Boards
Recombinant DNA Advisory Committee (RAC) March 2007
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- A Food-Based Approach to the Prevention of Gastrointestinal Tract Cancers
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- - Dr. Gary D. Stoner, The Ohio State University Comprehensive Cancer Center (2010/03/04)
- - Category : OCCAM Monthly Lecture Series
- NCI OCCAM Monthly Lecture Series
With the goal of informing the National Cancer Institute (NCI) community about the variety of ongoing research in cancer and complementary and alternative medicine (CAM), NCI's Office of Cancer Complementary and Alternative Medicine (OCCAM) has created a monthly lecture series on cancer CAM.
For more information, visit
http://www.cancer.gov/cam/news/monthly-lecture-series.html
A Food-Based Approach to the Prevention of Gastrointestinal Tract Cancers
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- Omega-3 Fatty Acids in the Dietary Management of Pro-Inflammatory States: A Nutrigenomic Model
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- - Dr. Peter Gillies, Central Research and Development, E.I. DuPont de Nemours & Co. (2010/03/04)
- - Category : Special
- NCI Stars in Nutrition Lecture Series
The molecular nutrition of omega-3 fatty acids provides a mechanistic underpinning for the development of therapeutic diets to offset the risk and/or the progression of disease through an integrated understanding of gentic predisposition, nutrient-gene interactions and appropriately timed nutritional pharmacology.
Omega-3 Fatty Acids in the Dietary Management of Pro-Inflammatory States: A Nutrigenomic Model
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- Great Teachers: Translation, Replication and Credibility of Research Findings
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- - Ioannidis, John P.
National Institutes of Health (U.S.) (2010/03/04) - - Category : Clinical Center Grand Rounds
- - Ioannidis, John P.
Great Teachers: Translation, Replication and Credibility of Research Findings
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- Context and Tissue Structure Determine Pattern Gene Expression and Phenotype in Normal and Malignant Breast (NIH-Only)
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- - Bissell, Mina.
National Institutes of Health (U.S.) (2010/03/04) - - Category : NCI CCR Grand Rounds (NIH Only)
- - Bissell, Mina.
Context and Tissue Structure Determine Pattern Gene Expression and Phenotype in Normal and Malignant Breast (NIH-Only)
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- NIH Extramural Administrative Officer Monthly Meeting - March 2007 (NIH Only)
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- - NIH (2010/03/04)
- - Category : Administrative Officer Meetings (NIH Only)
- NIH Extramural Administrative Officer Meeting
NIH Extramural Administrative Officer Monthly Meeting - March 2007 (NIH Only)
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- NBS Internal Requisitions HPOC Seminar - March 2007 (NIH Only)
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- - NBS (2010/03/04)
- - Category : NIH Only
Seminar for Internal Requisition Help Points of Contact.
NBS Internal Requisitions HPOC Seminar - March 2007 (NIH Only)
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- Demystifying Medicine - Infertility and Assisted Reproduction: Clinical and Basic Advances
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- - DeCherney, Alan H. (2010/03/04)
- - Category : Demystifying Medicine
Demystifying Medicine - Infertility and Assisted Reproduction: Clinical and Basic Advances
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- NSABB - National Science Advisory Board for Biosecurity, October, 2006
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- - National Science Advisory Board for Biosecurity (U.S.). Meeting 2006 : (2010/03/04)
- - Category : Advisory Boards
NSABB - National Science Advisory Board for Biosecurity, October, 2006
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- Migratory Properties and Immunological Consequences of Dendritic Cell Migration
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- - Uli Von Andrian (2010/03/04)
- - Category : Immunology
- The Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an annual Immunology Retreat.
For more information, visit
The Immunology Interest Group
Migratory Properties and Immunological Consequences of Dendritic Cell Migration
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- NCI Director's Awards Ceremony 2006 (NIH Only)
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- - NCI (2010/03/04)
- - Category : NIH Only
NCI Director's Awards Ceremony 2006 (NIH Only)
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- Regulatory Circuitry of Embryonic Stem Cells
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- - Richard A. Young, Ph.D., Massachusetts Institute of Technology (2010/03/04)
- - Category : Wednesday Afternoon Lectures
- The capacity of embryonic stem cells to self-renew and to give rise to virtually all somatic lineages holds much promise for human regenerative medicine. Moreover, embryonic stem cells provide a unique opportunity in which to study early development and cell fate decisions. We have begun to determine how transcription factors, chromatin regulators and signaling pathways control the gene expression programs responsible for stem cell self-renewal and pluripotency.
Using this genome-wide data, we have developed a model for the core regulatory circuitry of human embryonic stem cells.
For more information, visit
http://web.wi.mit.edu/young
NIH Director's Wednesday Afternoon Lecture
Regulatory Circuitry of Embryonic Stem Cells
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- Genomic Medicine and Cardiovascular Disease
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- - Elizabeth Nabel, M.D., Director, National Heart, Lung and Blood Institute (2010/03/04)
- - Category : Women's Health
- The Anita B. Roberts Lecture Series: Distinguished Women Scientists at NIH
The NIH Women Scientist Advisors (WSA) Committee is pleased to announce a new seminar series to highlight outstanding research achievements of women scientists in the Intramural Research Program at the NIH. The seminar series is dedicated to the memory of Dr. Anita B. Roberts, and honors her role as an exceptional mentor and scientist.
For more information, visit
http://orwh.od.nih.gov/news/robertslecture10-26-06.html
Genomic Medicine and Cardiovascular Disease
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- Natural Products: Challenges and Opportunities
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- - Ram Sasisekharan, Ph.D., Massachusetts Institute of Technology (2010/03/04)
- - Category : Special
- NCCAM Distinguished Lecture in the Science of Complementary and Alternative Medicine
Complex carbohydrates called glycans coat the surface of every cell in our bodies, but only recently have scientists been able to probe the structure of these compounds to understand their biological function and how they might be used to prevent or arrest disease. Dr. Ram Sasisekharan and his multidisciplinary team of researchers at MIT have developed a technique for rapidly sequencing these glycans, revealing their structure for the first time. They have discovered that glycans play a key role in the communications between cells that cause cells to divide, migrate and die. Dr.Sasisekharan and his team are pursuing ways to use glycans for diagnostic purposes and to develop alternative carbohydrate-based therapies for a variety of diseases including cancer. Ginseng, heparin and chondroitin have been the focus of recent studies. Please plan to attend and learn more about this new and promising area of research
Natural Products: Challenges and Opportunities
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- American Health Information Community - August 2006
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- - The U.S. Department of Health and Human Services (2010/03/04)
- - Category : American Health Information Community (AHIC)
- The American Health Information Community (the Community), is a committee established under the Federal Advisory Committee Act (Pub. L. No. 92-463, 5 U.S.C., App.), by the Secretary of the Department of Health and Human Services. The Community will advise the Secretary and recommend specific actions to achieve a common interoperability framework for health information technology (IT) and serve as a forum for participation from a broad range of stakeholders to provide input on achieving interoperability of health IT. The Community is made up of 17 voting members, including the Chair, and members have been appointed by the Secretary.
The Web address for the Community's draft charter is:
http://www.hhs.gov/healthit/ahiccharter.pdf
A complete list of members can be found at:
http://www.hhs.gov/healthit/ahic.html
American Health Information Community - August 2006
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- War of Nerves: Chemical Warfare from World War I to Al-Qaeda
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- - Tucker, Jonathan B.
National Institutes of Health (U.S.) (2010/03/04) - - Category : Emergency Preparedness and Biodefense
- - Tucker, Jonathan B.
War of Nerves: Chemical Warfare from World War I to Al-Qaeda
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- The Promises and Perils of Clinical Chemoprevention: 1980-2030
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- - Meyskens, F L.
National Institutes of Health (U.S.) (2010/03/04) - - Category : Special
- - Meyskens, F L.
The Promises and Perils of Clinical Chemoprevention: 1980-2030
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- NCI's Initiative for Chemical Genetics (NIH-Only)
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- - Schreiber, Stuart. (2010/03/04)
- - Category : NCI CCR Grand Rounds (NIH Only)
NCI's Initiative for Chemical Genetics (NIH-Only)
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- GMAC - The Times-They Are a Changing (HHS Only)
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- - Claycamp, Rebecca.
National Institutes of Health (U.S.) (2010/03/04) - - Category : HHS Only
- - Claycamp, Rebecca.
GMAC - The Times-They Are a Changing (HHS Only)