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  • Redox Reactions in Antigen Processing
    • - Peter Cresswell, Ph.D., Yale University School of Medicine (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Topics include the function of a gamma interferon inducible lysosomal enzyme (GILT) which reduces disulfide bonds in proteins. Its localization in class II-positive intracellular compartments in APCs suggested a role in antigen processing, and the enzymatic activity suggested that responses to antigens containing disulfide bonds might be affected. This was confirmed by analysis of GILT knock-out mice, which have clear deficiencies in generating CD4 T cell responses to such antigens.

    Peter Cresswell, Ph.D., HHMI, Professor, Deptartment of Immunobiology, Yale University School of Medicine

    For more information, visit
    http://www.med.yale.edu/immuno/fac_cresswell.html

    Redox Reactions in Antigen Processing

  • 2002 NIH Annual Women's History Month: The World of Women - Post 9/11
    • - National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Special

    2002 NIH Annual Women's History Month: The World of Women - Post 9/11

  • Anger and Conflict Management Part 2: Pulling Yourself Together - 10 Principles of Anger Reduction
    • - NIH Work and Family Life Center (WFLC) (2010/03/04)
    • - Category : Work/Life Center
    Anger and Conflict Management: A Three Part Series presented by the Employee Assistance Program

    Michael Bowler, Ph.D. and Eva Chen, M.S.W.

    An exploration of the social, emotional, cognitive, and behavioral aspects of anger in ourselves and in others.

    The NIH Work and Family Life Center (WFLC), in conjunction with the Employee Assistance Program, is pleased to announce the fourth annual "Faces and Phases of Life" seminar series. This successful series brings expert speakers to campus to address a broad range of quality of work and quality of life issues.

    For more information, visit the
    NIH Work and Family Life Center Faces & Phase of Life Seminar Series

    Anger and Conflict Management Part 2: Pulling Yourself Together - 10 Principles of Anger Reduction

  • Targeted Proteomics: A Study of the Interaction of a Ganglionic Blocker with the Neuronal Nicotinic Acetycholine Receptor
    • - Amina Woods, NIDA (2010/03/04)
    • - Category : Mass Spectrometry Interest Group of the NCI at Frederick
    Mass Spectrometry Interest Group at the NCI-Frederick

    Targeted Proteomics: A Study of the Interaction of a Ganglionic Blocker with the Neuronal Nicotinic Acetycholine Receptor

  • Mechanisms of DNA End Joining
    • - Tomkinson, Alan.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : DNA Repair

    Mechanisms of DNA End Joining

  • AED Monotherapy Workshop Day 1
    • - (2010/03/04)
    • - Category : Conferences
    Over the past decade there have been 8 new drugs approved for the treatment of epilepsy. Most of these have been approved initially as adjunctive therapy in highly refractory patients with partial seizures. Only two (felbamate and oxcarbazebine) received an indication for use as monotherapy at the time of approval. Subsequently, a third (lamotrigine) has received an indication for withdrawal to monotherapy in refractory patients.

    The use of antiepileptic drugs in monotherapy is supported by data from numerous clinical studies. Refractory patients treated with two or more drugs have better seizure control and fewer side effects when converted to monotherapy. Conversely, when newly diagnosed or refractory patients go from monotherapy to polytherapy, only a small percentage have a substantial reduction in seizures, and most have an increase in side effects.

    AED Monotherapy Workshop Day 1

  • Neurogenesis and Regeneration in the Adult Nervous System
    • - Fred H. Gage, Ph.D., Professor, Laboratory of Genetics, The Salk Institute for Biological Studies (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    The Principal Deputy Director, NIH, presents the 2001 Florence Mahoney Lecture
    Hosted by NIA; Reception sponsored by NINDS

    Neurogenesis and Regeneration in the Adult Nervous System

  • Fatherhood: The Most Important Job You'll Ever Have
    • - The NIH Work and Family Life Center (WFLC) (2010/03/04)
    • - Category : Work/Life Center
    There seem to be so many resources for moms - but what about dads? This workshop will explore the impact of social history, media, and past father/child relationships on current father/child relationships. We will discuss strategies for becoming an involved and effective father, and help you set personal goals for your role as a father.

    Fatherhood: The Most Important Job You'll Ever Have

  • New Approaches to Understanding Epileptogenesis
    • - Raymond J. Dingledine, Ph.D., Professor and Chairman Department of Pharmacology Emory University School of Medicine (2010/03/04)
    • - Category : Neuroscience
    NIH Neuroscience Seminar Series

    New Approaches to Understanding Epileptogenesis

  • Celebrating Plain Language at NIH
    • - Dirda, Michael.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Special

    Celebrating Plain Language at NIH

  • Incontinence in Women - A Women's Health Seminar
    • - Brown, Jeanette S.
      National Institutes of Health (U.S.). Office of Research on Women's Health. (2010/03/04)
    • - Category : Women's Health

    Incontinence in Women - A Women's Health Seminar

  • Structural Insights into Signal Recognition Particle Function
    • - Jennifer Doudna, Ph.D.
      Professor, and Associate Investigator, HHMI, Department of Molecular Biophysics and Biochemistry, Yale University

      Hosted by NIH Fellows (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    The Principal Deputy Director, NIH, presents the NIH Director's Wednesday Afternoon Lecture Series (WALS)

    Structural Insights into Signal Recognition Particle Function

  • Develop Your Interpersonal Effectiveness: Sharpen Your Emotional IQ
    • - The NIH Work & Family Life Center (2010/03/04)
    • - Category : Work/Life Center
    This workshop will address the concept of "emotional intelligence" and will help you develop strategies to respond and relate more effectively in various environments.

    Develop Your Interpersonal Effectiveness: Sharpen Your Emotional IQ

  • Structure and Function of Ionotropic Glutamate Receptors
    • - Eric Gouaux, Columbia University (2010/03/04)
    • - Category : Neuroscience
    NIH Neuroscience Seminar Series

    Structure and Function of Ionotropic Glutamate Receptors

  • Unclutter Your Office, Your Home, and Your Mind: A Guide to Personal Organization (Part 1)
    • - NIH Work and Family Life Center (WFLC) (2010/03/04)
    • - Category : Work/Life Center
    Many people talk about organizing, but certain hindrances keep them from doing it: not enough time, not enough energy, ever-increasing volumes of paper, ever-increasing work/life responsibilities, uncertainty about how to begin, fear of wastebasketry, and on and on.

    This seminar takes a holistic approach to helping participants establish order out of chaos. It focuses on the mental and physical steps necessary to create systems that work.

    The NIH Work and Family Life Center (WFLC), in conjunction with the Employee Assistance Program, is pleased to announce the fourth annual "Faces and Phases of Life" seminar series. This successful series brings expert speakers to campus to address a broad range of quality of work and quality of life issues.

    For more information, visit the
    NIH Work and Family Life Center Faces & Phase of Life Seminar Series

    Unclutter Your Office, Your Home, and Your Mind: A Guide to Personal Organization (Part 1)

  • Recent Studies of DNA Mismatch Repair
    • - Dr. Thomas Kunkel, NIEHS, Research Triangle Park, NC (2010/03/04)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group

    Recent Studies of DNA Mismatch Repair

  • Endoscopic Retrograde Cholangiopancreatography (ERCP) for Diagnosis and Therapy (Day 2)
    • - NIDDK, NCI, FDA and the NIH Office of Medical Applications of Research (2010/03/04)
    • - Category : Conferences
    ERCP is a procedure used by physicians to diagnose and treat problems in the liver, gallbladder, bile ducts, and pancreas. It combines the use of x-rays and an endoscope--a long, flexible, lighted tube. The physician inserts the endoscope in a patient's mouth and guides it down through the esophagus and into the stomach and small intestine. ERCP allows the physician to look inside these organs and also to send dye to the bile and pancreatic ducts, thereby making them visible on an x-ray.

    For more information, visit the
    conference web site

    Endoscopic Retrograde Cholangiopancreatography (ERCP) for Diagnosis and Therapy (Day 2)

  • NIH 2002 Dr. Martin Luther King, Jr. Commemoration Program
    • - Hrabowski, Freeman A.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Special

    NIH 2002 Dr. Martin Luther King, Jr. Commemoration Program

  • NRSA Training Grants and Fellowships
    • - NIAMS (2010/03/04)
    • - Category : Special
    GMAC Subcommittee on Training Seminar

    THIS SEMINAR WILL INCLUDE AN UPDATE OF NIH ACTIVITIES. OUR FEATURED TOPICS ARE AN IN-DEPTH REVIEW OF NRSA POLICY, THE PAYBACK SERVICE CENTER, A DEMONSTRATION OF ‘X-TRAIN’ (THE SYSTEM USED BY GRANTEES TO ELECTRONICALLY SUBMIT 2271 DATA), AND A BRIEF OVERVIEW OF THE NIAMS NRSA WORKSHOP FOR INSTITUTIONAL TRAINING GRANT ADMINISTRATORS HELD ON NOV. 15.

    SPEAKERS

    Marcia Hahn
    Assistant Grants Policy Officer, OPERA

    Grace Tuanmu
    Grants Management Officer, NIGMS

    Marie Willett
    Assistant to the Director, OER

    Tim Twomey
    Chief, User Support Branch, OPERA

    Jeff Thurston
    Grants Management Specialist, NIAMS

    NRSA Training Grants and Fellowships

  • Recombinant DNA Advisory Committee (RAC) Day 1
    • - Office of Biotechnology Activities (2010/03/04)
    • - Category : Advisory Boards
    The RAC is a technical committee whose goal is to consider the current state of knowledge and technology regarding recombinant DNA. This includes review of human gene transfer trials, and an assessment of the ability of DNA recombinants to survive in nature and the potential for transfer of genetic material to other organisms. It also considers hypothetical hazards and methods for monitoring and minimizing risks. Approximately one-third of the 15 members do not have scientific expertise but represent public interests and attitudes. This balance is intended to provide a forum for open public debate of social and scientific issues attendant to recombinant DNA research. The RAC has been overwhelmingly successful in achieving this goal.

    For more information, visit the
    Recombinant DNA Advisory Committee (RAC) Conference Web Site

    Recombinant DNA Advisory Committee (RAC) Day 1