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  • Discussion with Secretary Sebelius on recent trip to Africa (HHS Only)
    • - Kathleen Sebelius, Mary Wakefield, Nils Daulaire, Kevin DeCock (2011/08/13)
    • - Category : HHS Only
    On Thursday, August 11 Secretary Sebelius will host an event for HHS employees in the HHH auditorium to discuss her recent trip to Africa. She will be joined by HRSA Administrator Mary Wakefield, Office of Global Affairs Director Nils Daulaire, and the CDC???s Kevin DeCock.

    Discussion with Secretary Sebelius on recent trip to Africa (HHS Only)

  • NBS Travel HPOCs August 2011 Meeting (NIH Only)
    • - Jennifer Martin (2011/08/12)
    • - Category : NBS (NIH Only)
    Discussion of NBS travel system

    NBS Travel HPOCs August 2011 Meeting (NIH Only)

  • Achieving Health Equity for Sexual and Gender Minorities
    • - Dr. Judith Bradford, Director of the Center for Population Research in LGBT Health and Co-Chair of the Fenway Institute Boston, MA (2011/08/11)
    • - Category : Health Disparities
    NIH Health Disparities Seminar Series

    Lesbian, gay, bisexual, and transgender (LGBT) individuals are diverse with respect to sexual orientation, race/ethnicity, socioeconomic status and historical experience. Yet because they do not conform to the norm of exclusively heterosexual sexual orientation or traditional gender roles, these individuals share a history of marginalization. Data on the health of LGBT populations is sparse due to reluctance in some instances, to disclose personal information on sexual orientation and even stigmatization of researchers who focus on these populations. Responding to a need for a research agenda to address the health needs of LGBT populations, the Institute of Medicine (IOM) of the National Academies of Science recently issued a report entitled The Health of Lesbian, Gay, Bisexual and Transgender People: Building a Foundation for Better Understanding. The IOM reviewed existing literature, identified priority research areas, and made a set of research recommendations to increase knowledge about the LGBT population.

    Dr. Judith Bradford, one of the authors of the IOM report, will review current estimates on the size and distribution of sexual and gender minority population groups, discuss what is known about their health, explore methodological issues pertinent to the study of LGBT populations, and then summarize some of the IOMs key observations and recommendations. She is Director of the Center for Population Research in Lesbian, Gay, Bisexual, and Transgender Health at The Fenway Institute, which is funded by the Eunice Kennedy Shriver National Institute for Child Health and Human Development. Since 2001, she has worked with Fenway Health to expand its sexual and gender minority health research program and develop interventions to improve LGBT health and access to care.

    For more information, visit
    http://www.nimhd.nih.gov/hdss/hdss_June11.html

    Achieving Health Equity for Sexual and Gender Minorities

  • NCI Translational Science Meeting - July 2011 (Day 1)
    • - National Cancer Institute (2011/08/09)
    • - Category : Clinical Trials and Translational Research Advisory Committee
    The NCI Translational Science Meeting 2011: From Molecular Information to Cancer Medicine will explore the convergence of molecular information and clinical care, with the goal of accelerating early translational cancer research to speed therapeutic benefit to patients.

    For more information, visit: http://ncitranslates.nci.nih.gov

    NCI Translational Science Meeting - July 2011 (Day 1)

  • NCI Translational Science Meeting - July 2011 (Day 2)
    • - National Cancer Institute (2011/08/09)
    • - Category : Clinical Trials and Translational Research Advisory Committee
    The NCI Translational Science Meeting 2011: From Molecular Information to Cancer Medicine will explore the convergence of molecular information and clinical care, with the goal of accelerating early translational cancer research to speed therapeutic benefit to patients.

    For more information, visit: http://ncitranslates.nci.nih.gov

    NCI Translational Science Meeting - July 2011 (Day 2)

  • Peer-to-Peer Healthcare: How the internet is transforming health communications by providing us with access to information and each other
    • - Susannah Fox, Pew Research Centers Internet and American Life Project (2011/08/06)
    • - Category : Special
    The Medicine: Mind the Gap series explores a wide range of issues at the intersection of research, evidence, and clinical practice???especially areas in which conventional wisdom may lead us astray.

    Susannah Fox, Associate Director of the Pew Research Centers Internet and American Life Project, will discuss how changes in the health communications landscape have impacted how people search for healthcare information.

    Peer-to-Peer Healthcare: How the internet is transforming health communications by providing us with access to information and each other

  • 2011 NIH Directors Awards Ceremony(NIH Only)
    • - Dr. Francis Collins (2011/08/06)
    • - Category : NIH Only
    Annual ceremony where the NIH Director awards recipients with the highest honorary award given at NIH.

    2011 NIH Directors Awards Ceremony(NIH Only)

  • The Role of NIH in Ensuring a Bright Future for Physician-Scientists
    • - Leon Rosenberg, MD, Professor, Department of Molecular Biology, Princeton University (2011/08/06)
    • - Category : Clinical Center Grand Rounds
    Grand Rounds for Clinical Fellows

    For more information, visit: http://www.cc.nih.gov/about/news/grcurrent.html

    The Role of NIH in Ensuring a Bright Future for Physician-Scientists

  • Cancer Control: A Look at the future
    • - Judith Mackay, MBChB, FRCP, Asian Consultancy on Tobacco Control, Hong Kong (2011/08/05)
    • - Category : Special
    12th Annual Advances in Cancer Prevention Lecture

    This keynote lecture is part of the Summer Curriculum in Cancer Prevention and is sponsored by the Cancer Prevention Fellowship Program, a structured postdoctoral training program in the Center for Cancer Training at the National Cancer Institute. The goal of this program is to provide a strong foundation for physicians and scientists to train in the field of cancer prevention and control.

    Cancer Control: A Look at the future

  • NCI Town Hall Meeting - July 2011
    • - Harold Varmus (2011/08/03)
    • - Category : Special
    Harold Varmus will convene a town hall meeting in the Lipsett Amphitheater of the Warren Grant Magnuson Clinical Center at 11:00AM on Wednesday, July 27, to offer some observations on his first year as Director of the NCI.

    NCI Town Hall Meeting - July 2011

  • 14th Meeting of the Clinical Trials and Translational Research Advisory Committee (CTAC) Meeting
    • - NCI Coordinating Center for Clinical Trials (2011/07/28)
    • - Category : Clinical Trials and Translational Research Advisory Committee
    The Committee makes recommendations on the NCI-supported national clinical trials enterprise to build a strong scientific infrastructure by bringing together a broadly developed and engaged coalition of stakeholders involved in the clinical trials process.

    For more information, visit:
    http://deainfo.nci.nih.gov/advisory/ctac/ctac.htm

    14th Meeting of the Clinical Trials and Translational Research Advisory Committee (CTAC) Meeting

  • Grants.gov Quarterly Stakeholder Webcast - July 2011
    • - Boris DeSouza, Acting Director, Grants.gov Program Management Office (2011/07/27)
    • - Category : Grants.gov
    Grants.gov uses the quarterly webcasts to communicate the status of important program initiatives and operational status to stakeholders that include applicants, grantor agencies, OMB, and Congress. The webcasts also offer stakeholders the opportunity to interact with the PMO and guests through a live question and answer period.

    For more information, visit: http://www.grants.gov

    Grants.gov Quarterly Stakeholder Webcast - July 2011

  • Harnessing Systems Science Methodologies To Inform Public Policy: System Dynamics Modeling For Obesity Policy In The Envision Network
    • - Hazhir Rahmandad, Ph.D, Peter Hovmand, Ph.D., Alice Ammerman, Dr. P.H., Laura K. Brennan, PhD, MPH, (2011/07/26)
    • - Category : BSSR Lecture Series
    This symposium will demonstrate how systems science approaches (aka modeling and simulation) can be used to address policy-relevant questions, using childhood obesity as an exemplar. While doing so, it will showcase two mathematical (i.e., System Dynamics) models that are under development as a part of CompMod, the Comparative Modeling for Childhood Obesity Policy Network, which is part of the Envision network of mathematical and statistical modeling teams under NCCOR (the National Collaborative on Childhood Obesity Research).

    The symposium is designed to be accessible to audience members without a background in modeling. Each of two modeling projects will feature two speakers. The first speaker will describe the background of the problem that led to the need for mathematical models. The second speaker will explain the model building rationale and process along with some initial model outputs and interpretation. There will also be some description of: comparing models, the experiences and lessons learned in working on mathematical models for the first time, forming an interdisciplinary team, and working in a network of comparative modeling teams.

    Harnessing Systems Science Methodologies To Inform Public Policy: System Dynamics Modeling For Obesity Policy In The Envision Network

  • Meeting of the Interagency Autism Coordinating Committee - July 2011
    • - Dr. Thomas Insel (2011/07/26)
    • - Category : Interagency Autism Coordinating Committee
    IACC

    Meeting of the Interagency Autism Coordinating Committee - July 2011

  • Crowdsourcing: The Art and Science of Open Innovation
    • - NCRR, NIGMS, NIDA, NIBIB, PPPP and OBSSR (2011/07/24)
    • - Category : Conferences
    Crowdsourcing: The Art and Science of Open Innovation will explore new ways to incentivize innovation in biomedical research with the prize authority recently given to all federal agencies by Congress. The meeting will focus on the key aspects of this new approach that include: how to identify problems that can be solved through open innovation; how to communicate a scientific problem across disciplines???to a lay person or a technology geek; and how to test, evaluate and synergize the solutions.

    This meeting is co-sponsored by National Center for Research Resources (NCRR), National Institute of General Medical Sciences (NIGMS), National Institute on Drug Abuse (NIDA), National Institute of Biomedical Imaging and Bioengineering (NIBIB), Public-Private Partnership Program (PPPP) and Office of Behavioral and Social Sciences Research (OBSSR).

    For more information, visit: http://www.cvent.com/d/6dqym5/1Q

    Crowdsourcing: The Art and Science of Open Innovation

  • DOHS Seminar Series:Getting to Know Your Employee Assistance Program
    • - Ms. Eva Chen (2011/07/20)
    • - Category : Occupational Health & Safety Lectures (NIH Only)
    DOHS Seminar Series

    DOHS Seminar Series:Getting to Know Your Employee Assistance Program

  • NuRD complex and regulation of the epigenome
    • - Paul Wade, Ph.D. (NIEHS) (2011/07/20)
    • - Category : NIH Directors Seminars
    Directors Seminar Series

    NuRD complex and regulation of the epigenome

  • The Antimicrobial Defense of Drosophila: A Paradigm for Innate Immunity
    • - Dr. Jules Hoffmann (2011/07/16)
    • - Category : Wednesday Afternoon Lectures
    The last twenty years have experienced an unprecedented advance in our understanding of innate immunity in Metazoans and Plants. Up to the early nineties of the last century, little information had been obtained about pathogen recognition by the innate immune system and about the effector mechanisms induced by invading microorganisms. Drosophila, with its easily tractable genetics, can be credited with having made significant contributions to our present understanding of the basics of innate defenses.

    The presentation will review our current understanding, but will also address the many unresolved questions which await further in-depth analysis. A phylogenetic perspective will try to integrate the data obtained by studying Drosophila immunity, into the more general framework of invertebrate and vertebrate immune defenses

    The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    The Antimicrobial Defense of Drosophila: A Paradigm for Innate Immunity

  • Honoring the Scientific Legacy of Dr. Howard Nash
    • - Dr. Yves Pommier (2011/07/16)
    • - Category : Special
    Symposium highlighting the work of Dr. Howard Nash

    Honoring the Scientific Legacy of Dr. Howard Nash

  • Tales from the Cellular Underworld: mRNA Death Dealers
    • - Dr. Lynne Maquat, University of Rochester Center for RNA Biology (2011/07/10)
    • - Category : Wednesday Afternoon Lectures
    In mammalian cells, two different messenger ribonucleoproteins (mRNPs) serve as templates for protein synthesis. Newly synthesized CBP80-CBP20 (CBC)-bound mRNPs initially undergo a pioneer round of translation (Maquat et al., 2010). One purpose of this round of translation is to ensure the quality of gene expression, as exemplified by nonsense-mediated mRNA decay (NMD). NMD largely functions to eliminate mRNAs that prematurely terminate translation, although NMD also contributes to proper gene control, and it targets CBC-bound mRNPs (for recent publications, see Sato et al., 2008; Isken et al., 2008). CBC-bound mRNPs are remodeled to eIF4E-bound mRNPs as a consequence of the pioneer round of translation as well as independently of translation, e.g., by importin-b binding to importin-a-associated CBC (Sato and Maquat, 2009). eIF4E-bound mRNPs support the bulk of cellular protein synthesis and are the primary targets of mRNA decay mechanisms that conditionally regulate gene expression, such as Staufen1-mediated mRNA decay (see, e.g., Gong et al., 2009).

    Mechanistic aspects of NMD will be discussed, including how CBP80, which is acquired by the 5??? caps of newly synthesized transcripts within nuclei, promotes NMD at multiple steps by promoting specific mRNP rearrangements (Hwang et al., 2010). Mechanistic aspects of SMD will also be described, including the formation of Staufen1-binding sites not only by intramolecular base-pairing within an mRNA 3???-untranslated region but also by intermolecular base-pairing between the Alu element of an mRNA 3-untranslated region and a partially complementary Alu element within a long noncoding RNA (Gong and Maquat, 2011). These are new functions for Alu elements and for long noncoding RNAs, which we call ??-sbsRNAs.

    The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    Tales from the Cellular Underworld: mRNA Death Dealers