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  • Cross Contamination During Food Preparation (NIH Only)
    • - Elisa DuBreuil, MPH, Food Safety and Sanitation Officer, Division of Occupational Health and Safety (2012/11/18)
    • - Category : Occupational Health & Safety (NIH Only)
    DOHS Seminar Series focused on Employee Health and Safety.

    Elisa DuBreuil, MPH, RS, is a Lieutenant Commander in the United States Public Health Service detailed to the Division of Occupational Health and Safety as the Food Safety and Sanitation Officer. She is an Environmental Health Officer with a degree in Environmental Health and Safety Management from Ferris State University and a Master of Public Health from University of South Florida. She has worked in Public Health for 10 years: District Health Department #10 in Michigan, the Indian Health Service in Arizona and Nevada, the National Park Service in Florida, and has been with NIH for almost one year.

    The seminar series is sponsored by the Office of Research Services, Division of Occupational Health and Safety (DOHS), in partnership with the Division of Amenities and Transportation Services Wellness Program.

    Cross Contamination During Food Preparation (NIH Only)

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  • Town Hall - November 2012 (NIH Only)
    • - Lawrence Tabak (2012/11/18)
    • - Category : NIH Only
    Town Hall

    Please send comments to
    SUAAinfo@nih.gov

    Town Hall - November 2012 (NIH Only)

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  • Biobanking of Orphan Cancer: The Salivary Gland Model & An Australian Perspective on Biospecimens and Rare Diseases
    • - Adel K. El-Naggar, M.D., Ph.D., University of Texas, M.D. Anderson Cancer Center and Gareth Baynam, Ph.D., Genetic Services of Western Australia (2012/11/17)
    • - Category : Biospecimens
    Biospecimen Interest Group Meeting

    Biobanking of Orphan Cancer: The Salivary Gland Model
    Professor Adel K. El-Naggar, University of Texas,M.D.Anderson Cancer Center, Houston Texas

    An Australian Perspective on Biospecimens and Rare Diseases
    Dr. Gareth Baynam, Clinical Geneticist at the Genetic Services of Western Australia

    Biobanking of Orphan Cancer: The Salivary Gland Model & An Australian Perspective on Biospecimens and Rare Diseases

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  • The Molecular Mechanism of Synchronous Neurotransmitter Release at Synapses
    • - James E. Rothman, Ph.D., Director and Founder of the Nanobiology Institute, Yale School of Medicine (2012/11/17)
    • - Category : Wednesday Afternoon Lectures
    Membrane fusion is a fundamental biological process for organelle formation, nutrient uptake, and the secretion of hormones and neurotransmitters.

    Synchronous transmitter release enables neural circuits to keep pace, and results when docked synaptic vesicles are rapidly triggered to fuse with the pre-synaptic plasma membrane by calcium ions entering the nerve terminal. Membrane fusion in the nerve terminal and elsewhere is mediated by SNARE proteins, which assemble between the vesicle and plasma membrane. Biochemical studies have recently established that only two additional synapse-specific proteins？？？synaptotagmin and complexin？？？are needed to synchronize release by SNAREs and to add calcium dependence. Complexin cross-links assembling SNAREs into a highly co-operative array, freezing the frame of vesicle fusion to synchronize the readily-releasable pool. Upon binding calcium, Synaptotagmin releases the frozen SNAREs enabling them to rapidly complete assembly and release transmitter at the right time and place.

    James Edward Rothman is one of the world？？？s most distinguished biochemists and cell biologists and renowned for discovering the universal machinery that orchestrates the budding and fusion of membrane vesicles？？？a process essential to organelle formation, nutrient uptake, and secretion of hormones and neurotransmitters. He studied physics as an undergraduate at Yale and received his Ph.D. degree in biological chemistry from Harvard. He has been a professor at Stanford, Princeton, and Columbia, and founded and chaired the Department of Cellular Biochemistry and Biophysics at Memorial Sloan-Kettering Cancer Center. Dr. Rothman has received numerous awards and honors in recognition of his work including the Lasker Basic Science Award (2002), and the Kavli Prize for Neuroscience (2010). He is a member of the National Academy of Sciences and its Institute of Medicine, and a Fellow of the American Academy of Arts and Sciences.

    The NIH Directors Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. Lectures occur on most Wednesdays from September through June from 3:00 to 4:00 p.m. in Masur Auditorium, Building 10 on the NIH Bethesda campus.

    Each season includes some of the biggest names in biomedical and behavioral research. The goal of the WALS is to keep NIH researchers abreast of the latest and most important research in the Unites States and beyond. An added treat is the annual J. Edward Rall Cultural Lecture, which features top authors and other cultural icons. All speakers are nominated by the NIH community.

    For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    The Molecular Mechanism of Synchronous Neurotransmitter Release at Synapses

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  • ORF All Hands Meeting - November 2012 (NIH Only)
    • - Daniel Wheeland/ORF (2012/11/16)
    • - Category : NIH Only
    ORF will be presenting length of service awards to ORF Employees, as well as, updating all staff on current & future events, projects, etc.

    ORF All Hands Meeting - November 2012 (NIH Only)

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  • Contemporary Clinical Medicine: Great Teachers: Medical Writing for Non-Medical Readers
    • - Kent A. Sepkowitz, MD, Vice Chairman of Clinical Affairs; Director, Hospital Infection Control; Memorial Sloan-Kettering Cancer Center; and Professor of Medicine, Weill Cornell Medical College (2012/11/16)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Grand Rounds

    Contemporary Clinical Medicine: Great Teachers: Medical Writing for Non-Medical Readers

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    Contemporary Clinical Medicine: Great Teachers: Medical Writing for Non-Medical Readers

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  • NIH Common Fund National Centers for Biomedical Computing Showcase: (Day 1)
    • - NIH Common Fund (2012/11/15)
    • - Category : Conferences
    All are invited to participate in a special meeting of the National Centers for Biomedical Computing (NCBC), an NIH Common Fund program. The event will showcase the centers？？？ research, training and outreach activities as well as their other impact on the biomedical research community. The meeting also offers an opportunity to meet NCBC scientists and other program staff during poster sessions. Topics covered will be especially relevant to NIH discussions on big data and the importance of data management and analysis pipelines.

    The showcase will be held on November 8-9, 2012, in the Ruth L. Kirschstein Auditorium of the Natcher Conference Center (Building 45). It begins at 1:00 p.m. on November 8, with opening remarks from NIH Director Francis S. Collins, M.D., Ph.D.

    For more details, including the agenda, visit http://meetings.nigms.nih.gov/meetings/ncbc.

    For information about the NCBCs, see http://commonfund.nih.gov/bioinformatics/index.aspx.

    For more information go to http://meetings.nigms.nih.gov/meetings/ncbc/

    NIH Common Fund National Centers for Biomedical Computing Showcase: (Day 1)

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  • NIH Common Fund National Centers for Biomedical Computing Showcase (Day 2)
    • - NIH Common Fund (2012/11/15)
    • - Category : Conferences
    All are invited to participate in a special meeting of the National Centers for Biomedical Computing (NCBC), an NIH Common Fund program. The event will showcase the centers？？？ research, training and outreach activities as well as their other impact on the biomedical research community. The meeting also offers an opportunity to meet NCBC scientists and other program staff during poster sessions. Topics covered will be especially relevant to NIH discussions on big data and the importance of data management and analysis pipelines.

    The showcase will be held on November 8-9, 2012, in the Ruth L. Kirschstein Auditorium of the Natcher Conference Center (Building 45). It begins at 1:00 p.m. on November 8, with opening remarks from NIH Director Francis S. Collins, M.D., Ph.D.

    For more details, including the agenda, visit http://meetings.nigms.nih.gov/meetings/ncbc.

    For information about the NCBCs, see http://commonfund.nih.gov/bioinformatics/index.aspx.

    For more information go to http://meetings.nigms.nih.gov/meetings/ncbc/

    NIH Common Fund National Centers for Biomedical Computing Showcase (Day 2)

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  • NIH 2012 American Indian Heritage Month Observance Program: Serving Our People, Serving Our Nations, Native Visions for Future Generations (NIH Only)
    • - Jared B. Jobe, Ph.D., NCI, NIH (2012/11/15)
    • - Category : Native American (NIH Only)
    The National Institutes of Health (NIH) 2012 American Indian Heritage Month Observance Program will be held on Tuesday, November 13, 2012, from 11:00 a.m. - 12:00 p.m. at the Clinical Center, Building 10, in the Masur Auditorium. The national theme is ？？？Serving Our People, Serving Our Nations, Native Visions for Future Generations.？？？

    The keynote speaker Dr. Jared Jobe, Research Scientist, Division of Cancer Control and Population Sciences, National Cancer Institute (NCI) will present a talk on The Causes and Prevention of Chronic Disease in American Indians. He will discuss the social determinants of chronic disease in American Indian populations, and research approaches in community-based intervention trails to prevent chronic disease. The talk will focus on the two leading causes of death in American Indians: cardiovascular disease and cancer, as well as, describe recent and proposed preventative trials.

    Other NIH program participants include Lawrence Tabak, D.D.S., Ph.D., Deputy Director; Joyce A. Hunter, Ph.D., Deputy Director, NIMHD and Debra Chew, J.D., Director, OEODM.

    NIH 2012 American Indian Heritage Month Observance Program: Serving Our People, Serving Our Nations, Native Visions for Future Generations (NIH Only)

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  • DNA Recombination
    • - Dr Nancy Hollingsworth, SUNY Stony Brook, NY (2012/11/15)
    • - Category : DNA Repair
    DNA Repair Interest Group videoconference

    DNA Recombination

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  • Redox Biology - Carcinogenesis & Redox Enzymes
    • - G. Yeh; L. Ridnour (2012/11/11)
    • - Category : Redox Biology
    The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A.

    Each lecture will be 50 minutes with ample time for discussion and analysis. A handout for each lecture will be distributed on site.The participation of NIH postdoctoral and clinical fellows interested in redox biology is encouraged.

    For more information go to http://ccr.cancer.gov/ca reers/courses/rb

    Redox Biology - Carcinogenesis & Redox Enzymes

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  • NIH Academy Roundtable 2: The Patient-Physician Relationship Part II (NIH Only)
    • - Susan Persky, PhD, NHGRI, NIH (2012/11/10)
    • - Category : NIH Only
    The NIH Academy provides trainees with an overview of the scientific, social, economic, cultural, environmental, and policy factors that contribute to health disparities. This lecture focuses on the communication of genomic information to vulnerable populations.

    For more information go to https://www.training.nih.gov

    NIH Academy Roundtable 2: The Patient-Physician Relationship Part II (NIH Only)

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  • Geometric Folding Algorithms: Linkages, Origami, Polyhedra
    • - Dr. Erik Demaine, Professor of Computer Science at the Massachusetts Institute of Technology (2012/11/09)
    • - Category : Special
    Geometric Folding Algorithms: Linkages, Origami, Polyhedra

    Dr. Erik Demaine is one of the stars of the recent PBS program ？？？Between the Folds？？？. Examples of some of his amazing artwork are currently on display at the Renwick Gallery in D.C. His work has important implications for protein folding and social network analysis, as well as many other fields.

    What forms of origami can be designed automatically by algorithms? How might we build reconfigurable robots like Transformers or Terminator 3, hinging together a collection of pieces that dynamically reconfigure into arbitrary shapes? When can a robotic arm of rigid rods be folded into a desired configuration? What shapes can result by folding a piece of paper flat and making one complete straight cut? What 3D surfaces can be manufactured from a single sheet of material? How might proteins fold?

    Geometric folding is a branch of discrete and computational geometry that addresses these and many other intriguing questions. I will give a taste of the many results that have been proved in the past several years, as well as the several exciting unsolved problems that remain open. Many folding problems have applications in areas including manufacturing, robotics, graphics, and protein folding.

    Geometric Folding Algorithms: Linkages, Origami, Polyhedra

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  • TRACO: Radiation Oncology & Cancer Angiogenesis
    • - K.Camphausen; E.Zudaire (2012/11/09)
    • - Category : TRACO
    The Translational Research in Clinical Oncology course begins Sept. 10,2012. The course will feature two 1-hour sessions that will usually occur on Mondays, 4:00 ？？？ 6:00 pm in the Bldg. 50 ground floor auditorium (Rooms 1227/1233) with videoconferencing to Frederick National Lab(Bldg. 549, Rm. A). In addition, lectures will be archived at http://videocast.nih.gov.

    Each session will have two 50 minutes lectures in basic and clinical sciences with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov /careers/courses/traco

    TRACO: Radiation Oncology & Cancer Angiogenesis

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  • 60 Day Fitness Challenge Brown Bag Discussion
    • - Shanna Bernstein (2012/11/09)
    • - Category : Focus on You Wellness
    RW Fitness and Wellness Program

    Lecture on health and fitness for fitness program

    60 Day Fitness Challenge Brown Bag Discussion

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  • Ethical Issues in the Use of Stored Tissue; How to think about Incidental Findings
    • - Sara Hull PhD; Ben Berkman JD (2012/11/09)
    • - Category : Bioethics
    Ethical and Regulatory Aspects of Clinical Research

    Ethical Issues in the Use of Stored Tissue; How to think about Incidental Findings

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  • The Value of Clinical Clues in Solving Neurogenetic Riddles (HHS Only)
    • - Huda Y. Zoghbi, M.D., Texas Childrens Hospital (2012/11/09)
    • - Category : HHS Only
    Astute Clinician Lecture

    Dr. Zoghbi？？？s research interest is in using the tools of modern genetics to understand the proper development of the brain as well as what goes awry in specific neurodevelopmental and neurodegenerative conditions. She has published seminal work regarding the molecular basis of Rett syndrome and of late-onset neurodegenerative diseases. Dr. Zoghbi is a member of several professional organizations including the McKnight Foundation Neuroscience Board, the Lasker Jury, and serves as a senior editor for the newly founded journal eLife. Among Dr. Zoghbis honors are the E. Mead Johnson Award from the Society of Pediatric Research, the IPSEN prize in neuronal plasticity, the Bristol Myers-Squibb Neuroscience Distinguished Achievement Award, the Vilcek Prize, and the Gruber prize in Neuroscience. In 2000 she was elected to the Institute of Medicine, and in 2004 she was elected to the National Academy of Sciences.

    The NIH Directors Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. Lectures occur on most Wednesdays from September through June from 3:00 to 4:00 p.m. in Masur Auditorium, Building 10 on the NIH Bethesda campus.

    Each season includes some of the biggest names in biomedical and behavioral research. The goal of the WALS is to keep NIH researchers abreast of the latest and most important research in the Unites States and beyond. An added treat is the annual J. Edward Rall Cultural Lecture, which features top authors and other cultural icons. All speakers are nominated by the NIH community.

    For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    The Value of Clinical Clues in Solving Neurogenetic Riddles (HHS Only)

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  • NCI Board of Scientific Advisors - November 2012
    • - NCI (2012/11/08)
    • - Category : NCI Board of Scientific Advisors
    The 52nd meeting of the NCI Board of Scientific Advisors

    NCI Board of Scientific Advisors - November 2012

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  • Can We Win the War Against Cancer by Prevention?
    • - Zigang Dong, MD, DrPH (2012/11/08)
    • - Category : Stars in Nutrition
    Stars in Nutrition and Cancer

    The Stars lecture is titled Can We Win the War Against Cancer by Prevention? The aim of the lecture is to understand:
    • why cancer is still a major public health concern in the world

    • why prevention is critical to lowering the incidence of cancer worldwide

    • why nutritional foods are important for cancer prevention
    For more information go to http://prevention.cancer.gov/programs-resources/groups/ns/events/stars

    Can We Win the War Against Cancer by Prevention?

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  • Mechanisms underlying microbial translocation and therapeutic interventions to reduce microbial translocation-associated immune activation
    • - Jason M. Brenchley, Ph.D. (2012/11/07)
    • - Category : NIH Directors Seminars
    Directors Seminar Series:

    A multifaceted activation of the immune system is a hallmark of the chronic phase of immunodeficiency lentiviral infections. It is manifest by: increased T cell turnover, increased frequencies of T cells with an activated phenotype, and an increase in proinflammatory molecules in the plasma. Importantly, the extent of immune activation is a stronger predictor of disease progression than either CD4+ T cell count or plasma viral load.

    The importance of immune activation to pathogenesis in HIV/SIV infections is highlighted by the low levels of chronic activation seen in natural hosts of SIV that do not progress to AIDS. The consequences of immune activation include the generation of activated CD4+ T cell targets for the virus, attrition of the memory CD4+ T cell pool and high frequencies of terminally differentiated and exhausted memory T and B cells. However the underlying mechanisms of immune activation during infection are not well understood.

    We recently demonstrated that one cause of immune activation is the translocation of microbial products from the lumen of the intestine into the periphery. These microbial products can directly stimulate the immune system via pathogen associated molecular pattern recognition receptors, such as Toll like receptors. Our recent efforts have been aimed at understanding the mechanisms underlying microbial translocation and in studying potential therapeutic interventions which curb microbial translocation-induced immune activation.

    Mechanisms underlying microbial translocation and therapeutic interventions to reduce microbial translocation-associated immune activation

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