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  • Redox Biology - Inflammation & Epidemiology
    • - P. Hussain; S. Ambs (2012/10/19)
    • - Category : Redox Biology
    The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A.

    Each lecture will be 50 minutes with ample time for discussion and analysis. A handout for each lecture will be distributed on site.The participation of NIH postdoctoral and clinical fellows interested in redox biology is encouraged.

    For more information go to http://ccr.cancer.gov/ca reers/courses/rb

    Redox Biology - Inflammation & Epidemiology

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  • Risks and Benefits; Research Involving Persons at Risk for Impaired Decision-Making; Clinical Research with Pregnant Woman
    • - Dave Wendler PhD; Donald Rosenstein, MD; Maggie Little, PhD (2012/10/19)
    • - Category : Bioethics
    Ethical and Regulatory Aspects of Clinical Research

    Risks and Benefits; Research Involving Persons at Risk for Impaired Decision-Making; Clinical Research with Pregnant Woman

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  • Contemporary Clinical Medicine: Clinical/Translational Research: Separating Fact From Fiction
    • - Crystal Mackall, MD, Senior Investigator and Chief, Pediatric Oncology Branch, NCI (2012/10/19)
    • - Category : Clinical Center Grand Rounds
    Contemporary Clinical Medicine: Clinical/Translational Research: Separating Fact From Fiction

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    Contemporary Clinical Medicine: Clinical/Translational Research: Separating Fact From Fiction

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  • DeWitt Stetten, Jr., 50th Anniversary Symposium
    • - Carlos D. Bustamante, Kathy M. Giacomini and Tim Mitchison (2012/10/19)
    • - Category : DeWitt Stetten
    This symposium marks the 50th anniversary of the National Institute of General Medical Sciences. The speakers will talk about their NIGMS-supported research, how they recognize and develop exciting ideas, and how they train and mentor the next generation of biomedical scientists.

    Speakers:

    Carlos Daniel Bustamante, Ph.D. Professor of Biological Statistics and Computational Biology and Statistical Sciences and Associate Director, Center for Population and Comparative Genomics Stanford University ？？？Population Genetics in the Personal Genome Era: Genomics for the World？？？;

    Kathleen Giacomini, Ph.D. Professor of Biopharmaceutical Sciences, Pharmaceutical Chemistry, and Cellular and Molecular Pharmacology and Co-chair, Department of Bioengineering and Therapeutic Sciences University of California, San Francisco ？？？Shifting Paradigms for Pharmacologic Research？？？;

    Timothy Mitchison, Ph.D. Hasib Sabbagh Professor of Systems Biology and Deputy Chair of Systems Biology Harvard Medical School ？？？Microtubules: From Basic Biology to Cancer Drugs and Back Again？？？

    For more information go to http://www.nigms.nih.gov/News/Meetings/Stetten_2012.htm

    DeWitt Stetten, Jr., 50th Anniversary Symposium

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  • FELCOM Workshop: Careers in Science Editing (NIH Only)
    • - Ranjini Prithviraj Ph.D., Managing Editor at the American Chemical Society, Harrison Wein Ph.D., Science Writer/Editor at NIH Research Matters and NIH News in Health, Pam Hines, Ph.D., Senior Editor at Science Magazine, Cynthia Dunbar, Ph.D., Editor-in-chief, Blood (Journal of the American Society of Hematology), Christina Bennett, Ph.D., Editor at the American Psychological Society (2012/10/18)
    • - Category : NIH Only
    Have you always enjoyed communicating science? Have you ever wondered about a career in scientific writing and editing that goes beyond publishing academic papers? If so, then this seminar is for you. The seminar will explore the diverse opportunities in the area of science editing. The panel includes PhD level scientists who have successfully transitioned into careers in science editing at journals, non-profit organizations, and here at NIH. Fellows will learn how to successfully transition from the bench into the field, what types of jobs are available, and what entry-level requirements are necessary. After short introductions and presentations, the floor will be open for a question and answer session with the panelists. This event is sponsored by FELCOMs Career Development Subcommittee.

    For more information go to https://www.training.nih.gov

    FELCOM Workshop: Careers in Science Editing (NIH Only)

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  • TRACO: Breast Cancer & Small Molecules
    • - F.Zia; J. Marugan (2012/10/17)
    • - Category : TRACO
    The Translational Research in Clinical Oncology course begins Sept. 10,2012. The course will feature two 1-hour sessions that will usually occur on Mondays, 4:00 ？？？ 6:00 pm in the Bldg. 50 ground floor auditorium (Rooms 1227/1233) with videoconferencing to Frederick National Lab(Bldg. 549, Rm. A). In addition, lectures will be archived at http://videocast.nih.gov.

    Each session will have two 50 minutes lectures in basic and clinical sciences with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov /careers/courses/traco

    TRACO: Breast Cancer & Small Molecules

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  • TRACO: HIV & TGFbeta
    • - F.Maldarelli, S. Jakowlew (2012/10/13)
    • - Category : TRACO
    Two 1-hour sessions will usually occur on Mondays, 4:00 ？？？ 6:00 pm in the Bldg. 50 ground floor auditorium (Rooms 1227/1233) with videoconferencing to Frederick National Lab (Bldg. 549, Rm. A). In addition, lectures will be archived at http://videocast.nih.gov. Each session will have two 50-minutes lectures in basic and clinical sciences with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov/careers/courses/traco

    TRACO: HIV & TGFbeta

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  • Targeting Receptor Heteromers for the Treatment of Neuropsychiatric Disorders
    • - Sergi Ferre, M.D., Ph.D., Chief, CNS Receptor-Receptor Interactions Unit, NIDA (2012/10/12)
    • - Category : NIH Directors Seminars
    Director Seminar Series:

    Dr. Ferr？？s lab is interested in the role of receptor heteromers as targets for drug development in neuropsychiatric disorders and drug addiction. Receptor heteromers must be understood as dimeric or higher order molecular entities that are the result of combinatorial evolution and that are endowed with unique biochemical and functional properties that could be harnessed for therapeutic purposes. Their research deals preferentially with the discovery of heteromers of receptors that are targets for addictive drugs or that are localized in brain circuits that are involved in addictive behaviors (such as dopaminergic, cannabinoid, and adenosine receptors) and with the analysis of their biochemical and pharmacological properties involving studies at the cellular level as well as at the in vivo level. At the cellular level, mammalian cell lines transfected with the receptors under study are used to demonstrate receptor heteromerization by protein-protein interaction experiments. An important part of this research is devoted to finding the molecular determinants of receptor heteromerization. Mutants of the receptors lacking those determinants are used to demonstrate the unique biochemical characteristics of the receptor heteromers, which are then used to determine their existence in native tissues. In vivo models are established for the evaluation of the functional significance of receptor heteromers. The in vivo models include intracranial electrical stimulation, in vivo microdialysis, and protein phosphorylation (ex vivo analysis). The cellular and in vivo models complement each other and are also used to find ligands selective for receptor heteromers.

    Targeting Receptor Heteromers for the Treatment of Neuropsychiatric Disorders

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  • Redox Biology - Signal Transduction & Redox Physiology
    • - T. Moody, P. Pacher (2012/10/12)
    • - Category : Redox Biology
    The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is encouraged.

    Redox Biology will consist of two 1-hour lectures held on Tuesdays, 4:00-6:00 PM, Bldg. 50, Rms. 1227/1233. Each session will have a 50- minute lecture with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov/ca reers/courses/rb

    Redox Biology - Signal Transduction & Redox Physiology

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  • Fair Subject Selection; Undue Inducement; Ethical Issues in Research with Children
    • - Dave Wendler PhD; Robert Nelson MD PhD (2012/10/12)
    • - Category : Bioethics
    Ethical and Regulatory Aspects of Clinical Research

    Fair Subject Selection; Undue Inducement; Ethical Issues in Research with Children

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  • Frontiers in Basic Immunology (Day 1) (NIH Only)
    • - NCI CCR (2012/10/11)
    • - Category : NIH Only
    This NCI-sponsored conference will host international leaders in the field of basic immunology. The program includes recent advances in this field and this meeting should provide an exciting forum for discussion and debate on the current understanding of basic immunological mechanisms.

    For more information go to http://ncifrederick.cancer.gov/events/Immunology2012/

    Frontiers in Basic Immunology (Day 1) (NIH Only)

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  • NIH Research Festival 2012 - The NIH at 125: Todays Discoveries, Tomorrows Cures
    • - Gary Gibbons; Jennifer Lippincott-Schwartz; Ron Germain (2012/10/11)
    • - Category : Conferences
    NIH Research Festival Opening Plenary Session. Cholera, plague, smallpox and yellow fever. These were the four epidemic diseases subject to quarantine that most concerned Joseph James Kinyoun, the founder and, for several years, sole employee of the Laboratory of Hygiene in the U.S. Marine Hospital Service. The NIH traces its roots to Kinyouns one-room laboratory established in August 1887. At the 2012 NIH Research Festival we celebrate our quasquicentennial by honoring Kinyouns legacy, reflecting on NIH successes, and contemplating at the potential of the NIH Intramural Research Program (IRP) in the years to come.

    Where have we been, and where are we going? Smallpox has been eradicated, but much difficult work lies before us. Our 2012 Festival artwork, in fact, depicts MRSA bacteria, an emerging threat. This years plenary session opens with three big vision talks about possible futures for the NIH. Then, if travel permits, we will hear a lecture from the late Joseph Kinyoun himself, who surely will have much to say, having died 93 years ago. Kinyouns talk is followed by a panel discussion with NIH luminaries offering a personal and historical perspective of the IRP

    For more information, visit
    http://researchfestival.nih.gov

    NIH Research Festival 2012 - The NIH at 125: Todays Discoveries, Tomorrows Cures

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  • Beyond the Fig Leaf: The Science of Sex and Gender Differences - A Concurrent Session During the NIH Research Festival 2012
    • - Nakela Cook, Belinda Seto, Susan Taymans, Cora Lee Wetherington, Laura Johnson and Cher Dallal (2012/10/11)
    • - Category : Womens Health
    Personalized medicine provides the promise of improved healthcare informed by research on the factors that makes each human unique. Sex and gender are basic variables used to categorize differences and similarities; these variables influence health, including the experience, treatment, and outcomes of disease. The integration of sex and gender in the design and analysis of basic and clinical research studies can enhance the rigor of investigative approaches, improve the quality of the science, and expand the applicability of the results, supporting a personalized medicine approach that can transform public health.

    This session will cover aspects of sex and gender factors in health and disease, from the development of biomedical devices and therapeutics to the personalization of treatment of cardiovascular disease. Discussion of the latest scientific advances in sex differences research and enhancements in study design to detect sex and gender differences will engage and inform the NIH scientific community.

    Sex and Gender Differences in Cardiovascular Disease and Healthcare Delivery. Dr. Nakela Cook, Medical Officer in the Clinical Applications and Prevention Branch in the Division of Cardiovascular Sciences, NHLBI

    Sex and Gender Considerations in Devices and Therapeutics. Dr. Belinda Seto, Deputy Director of the National Institute of Biomedical Imaging and Bioengineering, NIBIB

    New Findings and Social/Policy Implications of Sex and Gender in Genetics and Genomics Basic/Clinical Research. Dr. Susan Taymans, Director for the Reproductive Genetics and Epigenetics Branch, NICHD

    Sex and Gender Differences in Chronic Pain Research. Dr. Cora Lee Wetherington, Women and Sex/Gender Differences Research Coordinator and Health Scientist Administrator, NIDA

    How to Power Studies to Conduct Sex and Gender Differences Research. Dr. Laura Johnson, Biostatistician, Office of Clinical and Regulatory Affairs, NCCAM

    Obesity-related hormones and endometrial cancer risk among post-menopausal women: The BFIT cohort Dr. Cher Dallal, FARE Award winner and Cancer Prevention Fellow, NCI

    For more information go to http://orwh.od.nih.gov/news/researchfestival2012.asp

    Beyond the Fig Leaf: The Science of Sex and Gender Differences - A Concurrent Session During the NIH Research Festival 2012

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  • Frontiers in Basic Immunology (Day2) (NIH Only)
    • - CCR (2012/10/09)
    • - Category : NIH Only
    This NCI-sponsored conference will host international leaders in the field of basic immunology. The program includes recent advances in this field and this meeting should provide an exciting forum for discussion and debate on the current understanding of basic immunological mechanisms. Sessions will include: Lymphocyte biology and signaling Adaptive and innate immune responses Immunity & disease

    For more information go to http://ncifrederick.cancer.gov/events/Immunology2012/

    Frontiers in Basic Immunology (Day2) (NIH Only)

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  • Redox Biology - Redox Biology & Angiogenesis
    • - D.Wink; D. Roberts (2012/10/07)
    • - Category : Redox Biology
    The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is encouraged.

    Redox Biology will consist of two 1-hour lectures held on Tuesdays, 4:00-6:00 PM, Bldg. 50, Rms. 1227/1233. Each session will have a 50- minute lecture with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov/ca reers/courses/rb

    Redox Biology - Redox Biology & Angiogenesis

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  • TRACO: Lymphoma & Topoisomerase Inhibitors
    • - W. Wilson; Y. Pommier (2012/10/05)
    • - Category : TRACO
    The Translational Research in Clinical Oncology course begins Sept. 10,2012. The course will feature two 1-hour sessions that will usually occur on Mondays, 4:00 ？？？ 6:00 pm in the Bldg. 50 ground floor auditorium (Rooms 1227/1233) with videoconferencing to Frederick National Lab(Bldg. 549, Rm. A). In addition, lectures will be archived at http://videocast.nih.gov.

    Each session will have two 50 minutes lectures in basic and clinical sciences with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov /careers/courses/traco

    TRACO: Lymphoma & Topoisomerase Inhibitors

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  • Scientific Management Review Board Meeting - October 2012
    • - Office of the Director (2012/10/05)
    • - Category : Scientific Management Review Board
    SMRB Advisory Committee Meeting

    For more information go to http://smrb.od.nih.gov

    Scientific Management Review Board Meeting - October 2012

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  • Purpose and Functions of IRBs; Informed Consent; Investigator Panel
    • - Barbara Karp, MD; Christine Grady RN PhD (2012/10/05)
    • - Category : Bioethics
    Ethical and Regulatory Aspects of Clinical Research

    Purpose and Functions of IRBs; Informed Consent; Investigator Panel

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  • Ethics Rounds: How Should Clinicians Handle Cases of Misattributed Parentage?
    • - Sally Haslanger, PhD, Massachusetts Institute of Technology & Lynne A. Wolfe, MS, CRNP, BC, Undiagnosed Diseases Program, NHGRI (2012/10/05)
    • - Category : Clinical Center Grand Rounds
    Ethics Rounds: How Should Clinicians Handle Cases of Misattributed Parentage?

    Investigators frequently uncover information about subjects unrelated to their studies, raising the challenge of when investigators should inform subjects of incidental findings. This challenge is perhaps most difficult when research findings indicate that a child is not biologically related to his or her parents. Please join us to discuss when investigators should share these findings with families.

    The program, which involves presentation and discussion of an actual case that occurred at the NIH, should be of interest to all individuals involved in research, as well as those interested in important issues in bioethics.

    Presenter: Lynne Wolfe, MS, CRNP, BC Undiagnosed Diseases Program, NHGRI

    Discussant: Sally Haslanger PhD, Professor of Philosophy and Director, Womens and Gender Studies Program, MIT.

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    Ethics Rounds: How Should Clinicians Handle Cases of Misattributed Parentage?

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  • Mitochondria: dynamic organelles critical for human health
    • - David C. Chan, M.D., Ph.D., California Institute of Technology (2012/10/05)
    • - Category : Wednesday Afternoon Lectures
    Mitochondria are dynamic organelles that fuse, divide, and move. Human genetic studies indicate that these processes are important for normal functioning of tissues, particularly neurons. Mutations in Mitofusion-2 (Mfn2) cause peripheral neuropathy (Charcot-Marie-Tooth 2A), and mutations in optic atrophy 1 (OPA1) cause eye disease (dominant optic atrophy). Mouse knockout studies focused on the mitofusins Mfn1 and Mfn2 have shown that mitochondrial fusion is important for organellar function. Dr. Chan will discuss mouse studies that reveal the physiological functions of mitochondrial dynamics. In addition, Dr. Chan will discuss how new mouse models can be combined with imaging approaches to understand the role of mitochondrial dynamics in neurodegeneration.

    The NIH Directors Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. Lectures occur on most Wednesdays from September through June from 3:00 to 4:00 p.m. in Masur Auditorium, Building 10 on the NIH Bethesda campus.

    Each season includes some of the biggest names in biomedical and behavioral research. The goal of the WALS is to keep NIH researchers abreast of the latest and most important research in the Unites States and beyond. An added treat is the annual J. Edward Rall Cultural Lecture, which features top authors and other cultural icons. All speakers are nominated by the NIH community.

    For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    Mitochondria: dynamic organelles critical for human health

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