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  • Reshaping Global Health: Translating Scientific Advances into Global Action
    • - Mark R. Dybul, M.D., Global Health Law Program, Georgetown University (2012/10/04)
    • - Category : Joseph J. Kinyoun
    Ambassador Mark R. Dybul, M.D., will outline guiding principles for a new global health approach focused on the overall health of people and communities, rather than the eradication of specific diseases, during the 2012 Joseph J. Kinyoun Memorial Lecture. Titled ???Reshaping Global Health: Translating Scientific Advances into Global Action,??? the NIAID-sponsored lecture will take place Tuesday, October 2 at 2 p.m. in the Lipsett Amphitheater, Bldg. 10.

    Dybul co-directs the Global Health Law Program in Georgetown University???s O???Neill Institute for National and Global Health Law, where he is also a distinguished scholar. He is also the inaugural global health fellow of the George W. Bush Institute.

    As former U.S. Global AIDS Coordinator (2006 to 2009), Dybul oversaw the implementation of the President???s Emergency Plan for AIDS Relief (PEPFAR), one of the largest international health initiatives in history aimed at addressing a single disease. In his discussion of the future of global health, Dybul will examine the need to reconfigure the funding of global health programs to be more centralized, efficient, innovative, free of conflicts of interest and drawn equitably from local sources.

    For more information, visit
    http://www.niaid.nih.gov/news/events/meetings/kinyounSeries/Pages/2012KinyounLecture.aspx

    Reshaping Global Health: Translating Scientific Advances into Global Action

  • Alveolar Stem Cells in Lung Development, Maintenance and Cancer
    • - Mark Krasnow, MD, PhD, Professor and Chairman, Department of Biochemistry Investigator, Howard Hughes Medical Institute (2012/10/04)
    • - Category : Stem Cell
    NIH CRM/SCIG Stem Cell Seminar Series (Extramural) presents Mark Krasnow. Mr. Krasnow is elucidating the genetic programs that control embryonic development of the Drosophila respiratory system and mammalian lung. He is especially interested in the developmental patterning mechanisms and the cell and molecular biology of these processes, and in using the information to understand lung disease and to regenerate a lung.

    Alveolar Stem Cells in Lung Development, Maintenance and Cancer

  • Neural Immune Connections: From Bench to Bedside & Beyond
    • - Esther M. Sternberg, M.D., University of Arizona at Tuscon (2012/10/03)
    • - Category : Anita B. Roberts
    The Anita B. Roberts Lecture Series: Distinguished Women Scientists at NIH

    Esther M. Sternberg, M.D., Research Director, Arizona Center for Integrative Medicine, University of Arizona at Tuscon, Formerly Chief, Section on Neuroendocrine Immunology and Behavior at NIMH.

    The lecture series was initiated by the WSA Committee in 2006, upon the suggestion of Marina Zaitseva. The aim of the lecture series is to highlight the outstanding research being carried out by women scientists in the NIH intramural program and to facilitate interaction of NIH women scientists at early stages of their career with leading women scientists. The seminar series has been dedicated to the memory of Anita B. Roberts and honors her role as an exceptional mentor and scientist.

    For more information go to http://sigs.nih.gov/wsa/Pages/Archives.aspx

    Neural Immune Connections: From Bench to Bedside & Beyond

  • Protein Homeostasis and Aggregation in Neurodegenerative Disease
    • - Ron Kopito, PhD, Stanford University School of Medicine (2012/10/03)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    Dr. Kopitos lab studies the cellular mechanisms that monitor protein biogenesis and ensure that only properly folded and assembled proteins are deployed within the cell. Proteins that fail to fold or assemble correctly can acquire alternative conformations that may give rise to highly toxic products. Therefore, cells contain machinery to recognize and destroy malfolded proteins. Mutations and genetic polymorphisms can result in the synthesis of misfolded polypeptides. Human genetic diseases therefore constitute a fertile source of naturally occurring mutants that provide insight into the nature of these quality control mechanisms. Both cis-acting mutations that directly affect the production of correctly assembled proteins and trans-acting mutations that affect the function of the cellular quality control machinery are linked to such diverse genetic disorders as cystic fibrosis and Lou Gehrigs and Huntingtons diseases.

    Research in the Dr. Kopitos lab is focused on two general questions: (1) How do cells make sure that only structurally correct proteins are deployed? How do cells discriminate between folded and misfolded proteins? Genetic biochemical and cell biological approaches are used to identify the machinery involved in recognizing and destroying misfolded proteins. (2) How do misfolded proteins acquire toxic properties that lead to cell death and ultimately to neurodegeneration? What mechanisms do neurons have to suppress the formation of such toxic conformers and why in some cases do these mechanisms fail? Biochemical biophysical and genetic approaches ranging from fluorescence spectroscopy to the creation of transgenic and knockout mice are applied to address these questions.

    For more information go to http://neuroseries.info.nih.gov

    Protein Homeostasis and Aggregation in Neurodegenerative Disease

  • Bridging the Terminology Gap in Pediatrics: Developing an Action Plan to Support the Continuum from Clinic to Research
    • - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the Pediatric Electronic Health Record Data Sharing Network (PEDSNet, through support from the AHRQ Enhanced Registries program) (2012/09/29)
    • - Category : Conferences
    This event will bring together leaders from government, academia, industry, and professional organizations in the field of Pediatrics to organize a governance structure and prioritization mechanism across multiple pediatric terminology efforts. This effort is aimed at harmonizing and bridging the continuum from research to health care delivery in pediatrics. Proposed topics of discussion at the conference include:
    • Rationale for a standardized pediatric terminology

    • Defining use cases suitable to guide this effort

    • Mapping out a framework for governance and implementation of pediatric terminology
    The anticipated outcomes of this conference are:
    • A consensus governance model

    • An initial set of procedures for structuring that model

    • An action plan for implementing terminologies

    • A set of next steps to formalize the governance process
    For conference-related questions, please contact Dr. Anjali Kastorf at 202-365-9034. Kastorf_Anjali@bah.com.

    For additional information or to register to attend in person or by live videocast, please visit the conference Web site (draft agenda also available here): http://www.cvent.com/d/tcq10l

    Bridging the Terminology Gap in Pediatrics: Developing an Action Plan to Support the Continuum from Clinic to Research

  • NIDA/FDA Population Assessment of Tobacco and Health (PATH) Study: Overview and Methods (HHS Only)
    • - Kevin Conway, Ph. D. (2012/09/29)
    • - Category : HHS Only
    Dr. Conway and other speakers will be discussing the methods and overviews of PATH project

    NIDA/FDA Population Assessment of Tobacco and Health (PATH) Study: Overview and Methods (HHS Only)

  • Thinking Differently about How We Teach Science: Why Should NIH Care, and What Can NIH Do
    • - Rodger Bybee, Director Emeritus of the Biological Sciences Curriculum Study (2012/09/29)
    • - Category : Science Education
    The Office of Science Education (OSE), ORIP, DPCPSI is hosting a new seminar series for everyone at NIH with an interest in science education, The NIH Science Education Conversations Series. This series will include topics ranging from learning about what the future holds for tomorrows science classroom to how to implement findings from research about the science of education.

    World-renowned science education expert Rodger Bybee, Director Emeritus of Biological Sciences Curriculum Study, will present the inaugural talk in this new series: ???Thinking Differently about How We Teach Science: Why Should NIH Care, and What Can NIH Do???? NIH can be a valuable contributor to the conversations surrounding science education. A goal of the series is to promote thinking and discussion on the NIH campus about current science education topics.

    Dr. Bruce Fuchs, Director of OSE, was inspired to organize these seminars by the 5-year strategic plan for science education currently being drafted by the White House Office of Science and Technology Policy. ???This is a way to let the NIH community know what is happening with the plan and how different agencies are moving forward. We plan to tap into other agencies such as NASA and NSF, as well as various think tanks and universities to get their perspectives on how to reform science education,??? says Dr. Fuchs.

    Thinking Differently about How We Teach Science: Why Should NIH Care, and What Can NIH Do

  • National Advisory Allergy and Infectious Diseases Council - September 2012 (NIH Only)
    • - Dr. Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases and Dr. Kathryn Zoon, Director, Division of Intramural Research (2012/09/28)
    • - Category : NIAID Council (NIH Only)
    The National Advisory Allergy and Infectious Diseases Council will be meeting in open session to hear presentations by the Institute Director and the Director of the Division of Intramural Research.

    National Advisory Allergy and Infectious Diseases Council - September 2012 (NIH Only)

  • TRACO: Ovarian Cancer & Prostate Cancer
    • - C. Annunziata; J. Gulley (2012/09/28)
    • - Category : TRACO
    The Translational Research in Clinical Oncology course begins Sept. 10,2012. The course will feature two 1-hour sessions that will usually occur on Mondays, 4:00 ??? 6:00 pm in the Bldg. 50 ground floor auditorium (Rooms 1227/1233) with videoconferencing to Frederick National Lab(Bldg. 549, Rm. A). In addition, lectures will be archived at http://videocast.nih.gov.

    Each session will have two 50 minutes lectures in basic and clinical sciences with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov /careers/courses/traco

    TRACO: Ovarian Cancer & Prostate Cancer

  • NIH Academy Short Course (Part II)
    • - Paula Goodwin, PhD, and Irene Dankwa-Mullen, PhD, NIMHD, NIH (2012/09/28)
    • - Category : Career Development/OITE
    The NIH Academy Short Course provides trainees with an overview of the scientific, socio-economic, cultural, environmental, and policy factors that contribute to health disparities. Parts I and II of the course will introduce trainees to actively engage in promoting a society in which all people live healthy lives and have equal access to health care.

    For more information go to https://www.training.nih.gov

    NIH Academy Short Course (Part II)

  • Framework for the Ethics of Research with Human Subjects; History, Scandals and Tragedies: Beecher, Tuskegee, Willowbrook and the Rest; Do the Codes Apply to My Research: Nuremberg, Helsinki, Belmont Report, CIOMS, The Common Rule
    • - Christine Grady RN PhD; Susan Lederer PhD; Ivor Pritchard PhD (2012/09/28)
    • - Category : Bioethics
    Ethical and Regulatory Aspects of Clinical Research

    Framework for the Ethics of Research with Human Subjects; History, Scandals and Tragedies: Beecher, Tuskegee, Willowbrook and the Rest; Do the Codes Apply to My Research: Nuremberg, Helsinki, Belmont Report, CIOMS, The Common Rule

  • Lunch and Learn Parenting Seminar: Middle School 101
    • - Abner Oakes (2012/09/28)
    • - Category : Parenting
    Middle School can be quite a culture shock to students and parents. Attend this seminar focused on the academic and social changes of middle school, expectations and requirements from the school, enhancing your child???s study and organizational skills, communication with teachers, how to support your child???s academics at home, and utilizing resources.

    Handout Slides

    For more information go to http://www.ors.od.nih.gov/pes/dats/childcare/Pages/index.aspx

    Lunch and Learn Parenting Seminar: Middle School 101

  • NICHD Advisory Council Meeting - September 2012
    • - NICHD (2012/09/27)
    • - Category : National Advisory Child Health and Human Development Council
    To help achieve the goals of the Institute, the NACHHD Council is charged with advising, consulting with, and making recommendations to the NICHD director on matters relating to the research and research support activities and functions of the Institute.

    NICHD Advisory Council Meeting - September 2012

  • Decision Related Activity and Top-down Attentional Modulations in Primate VI
    • - Eyal Seidemann, PhD, University of Texas at Austin (2012/09/27)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    Dr. Eyal Seidemann has pioneered the use of optical imaging in awake primates doing demanding psychophysical tasks, to probe the relationship between behavior and sensory signals in cortical maps. A fundamental feature of many sensory and motor areas is the use of orderly maps for the representation of sensory and motor signals. In these maps, the value of the parameter computed by individual neurons (e.g., the orientation of a line segment; the direction and amplitude of a planned eye movement) changes systematically across one or two dimensions of a neural structure. Incoming neural signals, therefore, are rapidly transformed into a ???place code??? ??? where the spatial pattern of activity within the map conveys information about a sensory stimulus or a planned movement. Because sensory and motor neurons are typically coarsely tuned, that is, each neuron responds to a broad range of stimulus or movement parameters, any stimulus or motor response elicits neural activity that is distributed over a large population of neurons within the neural map.

    Using a novel combination of optical imaging and electrophysiological techniques in awake, behaving primates, Dr. Seidemann has directly visualized the functional organization and the spatial pattern of population activity in cortical maps in real-time, while subjects perform demanding, well controlled, perceptual, cognitive, or motor tasks. These observations are combined with computational models that attempt to explain how the measured neural activity could lead to the observed behavior. These models are further tested by measuring how perceptual judgments or motor plans change following selective manipulations of the neural response by microstimulation or pharmacological microinjections. This unique combination of approaches puts Dr. Seidemann???s work at the forefront of modern attempts to explain the link between activity in sensory neurons and behavior.

    For more information go to http://neuroseries.info.nih.gov

    Decision Related Activity and Top-down Attentional Modulations in Primate VI

  • AIDS Research Advisory Committee Meeting - September 2012 (NIH Only)
    • - Division of AIDS, NIAID (2012/09/27)
    • - Category : AIDS Research Advisory Committee (NIH Only)
    One of three annual meetings of the AIDS Research Advisory Committee, which advises the Director of the Division of AIDS and NIAID.

    AIDS Research Advisory Committee Meeting - September 2012 (NIH Only)

  • Redox Biology - Introduction & Redox Chemistry
    • - T. Moody; D. Wink (2012/09/27)
    • - Category : Redox Biology
    The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is encouraged.

    Redox Biology will consist of two 1-hour lectures held on Tuesdays, 4:00-6:00 PM, Bldg. 50, Rms. 1227/1233. Each session will have a 50-minute lecture with ample time for discussion and analysis. A handout for each lecture will be distributed on site.

    For more information go to http://ccr.cancer.gov/careers/courses/rb

    Redox Biology - Introduction & Redox Chemistry

  • Translational Research on Child Neglect Consortium: Research on Child Neglect, Progress Over a Decade
    • - NIDA, NIMH, NICHD, OBSSR, and NIH Child Abuse and Neglect Working Group (2012/09/26)
    • - Category : Special
    Home Visitation and Child Neglect

    This special seminar for the community is part of the meeting entitled: Translational Research on Child Neglect Consortium: Research on Child Neglect, Progress Over a Decade. The seminar will highlight recent research on home visitation to reduce child neglect.

    Chair: Cheryl Anne Boyce, Ph.D.

    Introduction and Community Welcome
    Agnes Leshner, Director, Child Welfare Services, Montgomery County.

    Nurse Home Visitation: Lessons Learned for Prevention of Child Neglect
    David Olds, Ph.D., University of Colorado.

    Child Neglect and Home Visitation from Two Perspectives
    Anne Duggan, Ph.D., Johns Hopkins University.

    DISCUSSANT Brenda Jones Harden, Ph.D., University of Maryland at College Park.

    For more information go to http://www.trcnconsortium.com/2012AnnualMeeting.htm

    Translational Research on Child Neglect Consortium: Research on Child Neglect, Progress Over a Decade

  • Molecular Imaging of Infectious Diseases: Current Status and Future Challenges
    • - Center for Infectious Disease Imaging (CIDI) at NIH and the Center for Infection and Inflammation Imaging Research at the Johns Hopkins University School of Medicine (2012/09/26)
    • - Category : Conferences
    The Center for Infectious Disease Imaging (CIDI) at NIH and the Center for Infection and Inflammation Imaging Research at the Johns Hopkins University School of Medicine will host a meeting about molecular imaging applications in infectious disease research. Topics will include novel bacterial, mycobacterial and viral molecular imaging applications as well as molecular imaging techniques targeting the immune system. Cancer and cardiovascular molecular imaging researchers, infectious disease researchers and others in the field will interface.

    Molecular Imaging of Infectious Diseases: Current Status and Future Challenges

  • The Science of Injury Prevention Research: Past Successes and Future Challenges
    • - Andrea C. Gielen, ScD, ScM, Johns Hopkins Center for Injury Research and Policy (2012/09/26)
    • - Category : BSSR Lecture Series
    NIH Behavioral and Social Sciences Research Lecture Series (BSSR) Sponsored by the Office of Behavioral and Social Sciences Research, Office of the Director, NIH

    Abstract: Injuries, unintentional and violent, are the leading cause of death from ages 1 to 44 and they are the second most costly health problem in America. Prevention research in the injury field has matured over the last few decades and results offer optimism for reducing this toll in the future. This talk will provide an overview of the field, its history of accomplishments, as well as the challenges and opportunities that face it in the future. An emphasis will be placed on prevention research of particular relevance to the NIH mission and institutes, with examples drawn from injuries that affect the population across the lifespan.

    Bio: Dr. Gielen???s research interests are in the development and evaluation of community and clinic-based programs that address health behavior problems affecting women and children, primarily among low-income families in urban areas. The application of behavioral sciences to childhood injury control and domestic violence prevention programs, and the relationship between violence and HIV risk are areas of special focus. Childhood injury problems of particular interest are fires, burns, CO poisoning, and motor vehicle crashes. Dr. Gielen???s current research focuses on the use of computers for patient and public safety education; community interventions to improve home safety; translation research to disseminate proven injury prevention interventions; the impact of housing conditions on child safety; and stage tailored clinical interventions for survivors of domestic violence living with or at risk for HIV/AIDS.

    For more information go to https://videocast.nih.gov/FutureEvents.asp

    The Science of Injury Prevention Research: Past Successes and Future Challenges

  • Medicine: Mind the Gap - Evidence-Informed Factors for Promoting Psychological Resilience in the U.S. Military
    • - Terry Tanielian, RAND Corporation (2012/09/25)
    • - Category : Medicine: Mind the Gap
    Ms. Tanielian will discuss the concept of psychological resilience and highlight how the U.S. Department of Defense has implemented programs to promote psychological resilience in an effort to prepare troops and their families for the challenges of deployment. She also will review how these approaches have evolved over the past several years and how the concept of Total Force Fitness is shaping future training and prevention efforts within the military.

    Ms. Tanielian is a senior analyst at the RAND Corporation. She received an M.A. in psychology from American University. Her areas of research interest include the psychological effects of combat, terrorism and disasters, psychological resilience and suicide prevention, as well as access to, and quality of, behavioral healthcare for returning veterans. Ms. Tanielian has worked on several studies on the behavioral health-related needs of returning Operation Enduring Freedom/Operation Iraqi Freedom veterans and their families, including co-leading the landmark study, ???Invisible Wounds of War.??? Ms. Tanielian is currently leading a new prospective longitudinal study to follow military families across a deployment cycle and is also the lead on a study to assess the veteran support programs under the Welcome Back Veterans Initiative. She is serving as a co-investigator on a large randomized controlled trial to examine the effectiveness of stepped care for post-traumatic stress disorder and depression within the U.S. Army and has published several peer-reviewed articles and book chapters, and served on numerous working groups and expert panels. Ms. Tanielian serves as an ad hoc reviewer for multiple scientific journals. From 2004 to 2012, she directed RAND Corporation???s Center for Military Health Policy Research; in this capacity, she oversaw RAND???s diverse portfolio of research on issues related to military and veterans??? healthcare policy. Ms. Tanielian also was a member of the planning committee for the 2010 Rosalynn Carter Symposium on Mental Health Policy, which focused on the mental health needs of returning veterans.

    The Medicine: Mind the Gap seminar series explores a wide range of issues at the intersection of research, evidence, and clinical practice, especially areas in which conventional wisdom may be misleading. The seminar series aims to engage the National Institutes of Health community in thought-provoking discussions to challenge what we think we know and to think critically about our role in today???s research environment. Seminars to date have explored gaps between ethical theory and medical practice, the role of medical evidence in reducing practice variation and controlling costs, and special challenges of ???rules of evidence??? in translational research.

    For more information go to http://prevention.nih.gov/mindthegap/tanielian.aspx

    Medicine: Mind the Gap - Evidence-Informed Factors for Promoting Psychological Resilience in the U.S. Military