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  • Molecular Mechanisms for Protein-Encoded Inheritance
    • - Dr. David Eisenberg, UCLA (2010/11/18)
    • - Category : Structural Biology
    The SBIG is a clearinghouse for discussions and interactions between scientists interested in all aspects of molecular structure, from experimental determination by x-ray crystallography, electron microscopy, mass spectrometry, and NMR, to theoretical and computational biology and biophysics, and to the biological application of structural data.

    For more information, visit
    Structural Biology Interest Group

    Molecular Mechanisms for Protein-Encoded Inheritance

  • Graduate Programs in Psychology
    • - Sponsored by the NIH Office of Intramural Training & Education (2010/11/18)
    • - Category : Career Development/OITE
    Learn about educational programs (master???s and doctorate level) as well as career opportunities in the field of psychology.

    Speaker:
    Kim J. Nickerson, PhD, Assistant Dean, College of Behavioral and Social Sciences, University of Maryland College Park

    Graduate Programs in Psychology

  • White Oak Relocation (HHS Only)
    • - Center for Biologics Evaluation & Research (2010/11/18)
    • - Category : HHS Only
    White Oak Relocation Presentation

    US Dept of Health and Human Services

    Center for Biologics Evaluation & Research

    White Oak Relocation (HHS Only)

  • High Risk/Triple Negative Breast Cancer
    • - Newman, Lisa.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Health Disparities
    NIH Health Disparities Seminar Series

    In recognition of National Breast Cancer Awareness Month, the theme for the October seminar series is ???Confronting Breast Cancer Disparities.??? With the exception of non-melanoma skin cancer, breast cancer is the most common form of cancer in women. It is the second deadliest cancer in White, African American, Asian, Pacific Islander and American Indian/Alaska Native women, and the number one cause of cancer death in Hispanic women, according to the Centers for Disease Control and Prevention. The NCI???s Surveillance, Epidemiology, and End Results (SEER) program, reports that African American women are less likely to be diagnosed with breast cancer compared to White women, yet they are more likely to die from breast cancer.

    Dr. Lisa Newman, Professor of Surgery and Director of the University of Michigan???s Breast Care Center will be the keynote speaker. Her research focuses on ethnicity-related variation in breast cancer risk and outcome. The presentation will look at high risk breast cancer in women of African ancestry, and highlight preliminary findings from an international research partnership between the University of Michigan and the Komfo Anoyke Teaching Hospital in Kumasi Ghana. It involves the study of breast disease patterns and genotype markers in western, sub-Saharan Africans compared with those of African Americans and White Americans.

    www.ncmhd.nih.gov

    High Risk/Triple Negative Breast Cancer

  • Understanding the Increased Prevalence of Autism
    • - Peter S. Bearman, PhD, Columbia University (2010/11/18)
    • - Category : BSSR Lecture Series
    This lecture is an installment of the Behavioral and Social Sciences Research Lecture Series sponsored by the NIH Office of Behavioral and Social Sciences Research and organized by the NIH Behavioral and Social Sciences Research Coordinating Committee.

    The Behavioral and Social Sciences Research Coordinating Committee (BSSR CC), with support from the Office of Behavioral and Social Sciences Research (OBSSR), convenes a series of guest lectures and symposia on selected topics in the behavioral and social sciences. These presentations by prominent behavioral and social scientists provide the NIH community with overviews of current research on topics of scientific and social interest. The lectures and symposia are approximately 50 minutes in length, with additional time for questions and discussion. All seminars are open to NIH staff and to the general public.

    Understanding the Increased Prevalence of Autism

  • Dual Use Concerns In Life Sciences Research: An International Dialogue (English)
    • - Cuervo, Luis Gabriel.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    Life sciences research that is conducted for legitimate scientific purposes but produces information, knowledge, or technology that may be misused to threaten human, animal or plant health and/or national security is termed dual use research. Effective global dialogue on concerns and issues regarding dual use life sciences research is key to achieving an effective balance between public health priorities and national security concerns. Numerous national- and international-level activities are currently underway to raise awareness of the risks posed by dual use life sciences research as well as to address or manage these risks while, at the same time, promoting responsible life sciences research. In the United States, the government has established the National Science Advisory Board for Biosecurity (NSABB) to provide advice and recommendations on addressing risks presented by dual use life sciences research. This international Videocast focusing on the Americas is the first in a series of internet-based meetings aimed at engaging the international community by region. Program
    • What is ???dual use research??? and ???dual use research of concern????
    • How can risks associated with ???dual use research of concern be meaningfully assessed?
    • What strategies for managing and/or addressing these risks have been proposed or implemented?
    • What is being done to strengthen research governance in the Americas?
    The audio and captioning will be in English.

    http://oba.od.nih.gov/biosecurity/internationalwebcast.html

    Presenters:

    Luis Gabriel Cuervo, M.D. , Senior Advisor, Research Promotion and Development, Area of Technology Health Care & Research (THR/RP), Pan American Health Organization (PAHO)

    David R. Franz, D.V.M., Ph.D., Chair of NSABB International Engagement Working Group, Midwest Research Institute;

    Dennis L. Kasper, M.D., NSABB Chair, Harvard Medical School;

    Stuart B. Levy, M.D. Co-Chair of NSABB International Engagement Working Group, Tufts School of Medicine; and

    Amy P. Patterson, M.D., Acting Associate Director for Science Policy, National Institutes of Health

    Dual Use Concerns In Life Sciences Research: An International Dialogue (English)

  • Pre-Application Meeting for the Community Networks Program ??? Centers for Reducing Cancer Disparities through Outreach, Research and Training
    • - to Reduce Cancer Health Disparities, National Cancer Institute, National Institutes of Health (2010/11/18)
    • - Category : Special
    pre-application meeting for the RFA-CA-09-032, Community Networks Program-Centers for Reducing Cancer Disparities through Outreach, Research and Training, is for all interested prospective applicants. The meeting will include: (1) a presentation by the NCI program staff members to explain the objectives of the Community Networks Program and goals and requirements for Centers for Reducing Disparities through Outreach, Research and Training; (2) discussion (by the NCI review staff members) of the application peer review process; and (3) questions and answers session. An NCI Grants Management Specialist will be available to answer grant administration questions.

    For more information: http://crchd.cancer.gov/

    Pre-Application Meeting for the Community Networks Program ??? Centers for Reducing Cancer Disparities through Outreach, Research and Training

  • Dual Use Concerns In Life Sciences Research: An International Dialogue (Spanish)
    • - Cuervo, Luis Gabriel.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    Life sciences research that is conducted for legitimate scientific purposes but produces information, knowledge, or technology that may be misused to threaten human, animal or plant health and/or national security is termed dual use research. Effective global dialogue on concerns and issues regarding dual use life sciences research is key to achieving an effective balance between public health priorities and national security concerns. Numerous national- and international-level activities are currently underway to raise awareness of the risks posed by dual use life sciences research as well as to address or manage these risks while, at the same time, promoting responsible life sciences research. In the United States, the government has established the National Science Advisory Board for Biosecurity (NSABB) to provide advice and recommendations on addressing risks presented by dual use life sciences research. This international Videocast focusing on the Americas is the first in a series of internet-based meetings aimed at engaging the international community by region. Program
    • What is ???dual use research??? and ???dual use research of concern????
    • How can risks associated with ???dual use research of concern be meaningfully assessed?
    • What strategies for managing and/or addressing these risks have been proposed or implemented?
    • What is being done to strengthen research governance in the Americas?
    The audio and captioning will be in Spanish.

    http://oba.od.nih.gov/biosecurity/internationalwebcast.html

    Presenters:

    Luis Gabriel Cuervo, M.D. , Senior Advisor, Research Promotion and Development, Area of Technology Health Care & Research (THR/RP), Pan American Health Organization (PAHO)

    David R. Franz, D.V.M., Ph.D., Chair of NSABB International Engagement Working Group, Midwest Research Institute;

    Dennis L. Kasper, M.D., NSABB Chair, Harvard Medical School;

    Stuart B. Levy, M.D. Co-Chair of NSABB International Engagement Working Group, Tufts School of Medicine; and

    Amy P. Patterson, M.D., Acting Associate Director for Science Policy, National Institutes of Health

    Dual Use Concerns In Life Sciences Research: An International Dialogue (Spanish)

  • NCI Directors Consumer Liaison Group 52nd Meeting (Day 3)
    • - National Cancer Institute (2010/11/18)
    • - Category : Directors Consumer Liaison Group
    is the 52nd meeting of the National Cancer Institute Director???s Consumer Liaison Group (DCLG). The DCLG is NCI???s all-consumer advisory committee that indentifies and responds to issues and challenges facing the Institute at the request of the Director. The DCLG provides relevant, non-scientific skills and perspectives in order to improve research outcomes by identifying new approaches, promoting innovation, recognizing unforeseen risks or barriers, and identifying unintended consequences that could result from NCI decisions. This meeting will focus on NCI???s therapeutics development program as well as provide updates on the NCI National Outreach Network and the DCLG Advocate???s in Research Working Group.

    http://dclg.cancer.gov

    NCI Directors Consumer Liaison Group 52nd Meeting (Day 3)

  • Interagency Autism Coordinating Committee
    • - Interagency Autism Coordinating Committee (U.S.) (2010/11/18)
    • - Category : Conferences
    The Interagency Autism Coordinating Committee (IACC) coordinates all efforts within the Department of Health and Human Services (HHS) concerning autism spectrum disorder (ASD). Through its inclusion of both Federal and public members, the IACC helps to ensure that a wide range of ideas and perspectives are represented and discussed in a public forum.

    The IACC mission is to:
  • Facilitate the efficient and effective exchange of information on ASD activities among the member agencies
  • Coordinate ASD-related activities
  • Increase public understanding of the member agencies activities, programs, policies, and research by providing a public forum for discussions related to ASD research, screening, education, and interventions


  • IACC meetings are open to the public and include presentations and discussions about member activities and projects of the IACC. The meetings also include scientific presentations from investigators in the field of ASD research. A portion of each meeting is reserved for public comment. A summary of each meeting is posted on the meetings & events page of the IACC website.

    Interagency Autism Coordinating Committee

  • Pre-Application Workshop on RFA OD-09-010, Building Community Research Infrastructure (Morning Session)
    • - Suzanne Heurtin-Roberts, Ph.D., M.S.W. (2010/11/18)
    • - Category : Special
    This pre-application workshop provides a general overview and orientation to the purpose and requirements of NIH Request for Applications OD-09-010, Building Sustainable Community-Linked Infrastructure to Enable Health Science Research (RC4). The purpose of the workshop is to prepare potential applicants for funding through this RFA to develop a sound and competitive application. There will be capacity to submit questions through email during the workshop to be answered live.

    Pre-Application Workshop on RFA OD-09-010, Building Community Research Infrastructure (Morning Session)

  • Pre-Application Workshop on RFA OD-09-010, Building Community Research Infrastructure (Afternoon Session)
    • - Suzanne Heurtin-Roberts, Ph.D., M.S.W. (2010/11/18)
    • - Category : Special
    This pre-application workshop provides a general overview and orientation to the purpose and requirements of NIH Request for Applications OD-09-010, Building Sustainable Community-Linked Infrastructure to Enable Health Science Research (RC4). The purpose of the workshop is to prepare potential applicants for funding through this RFA to develop a sound and competitive application. There will be capacity to submit questions through email during the workshop to be answered live.

    Pre-Application Workshop on RFA OD-09-010, Building Community Research Infrastructure (Afternoon Session)

  • Survival from Hypoxia: The Critical Role of Protein Homeostasis
    • - Crowder, Michael W.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Neuroscience
    C. Michael Crowder, the Seymour and Rose T. Brown Professor in the Department of Anesthesiology at the Washington University School of Medicine, is both a clinical anesthesiologist and an experimental geneticist who uses the nematode C. elegans to investigate questions of importance to neurobiology. One focus of the Crowder lab, which is the subject of his lecture in the Neuroscience Series, is the genetic basis for the capacity of C. elegans to survive bouts of hypoxia. This work, which has obvious clinical relevance, has uncovered important connections between protein homeostasis and the ability of organisms to deal with hypoxic insults.

    For more information see our website - http://neuroseries.info.nih.gov

    Survival from Hypoxia: The Critical Role of Protein Homeostasis

  • TRACO: Genomics and Case Report
    • - Olaku, O.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : TRACO
    For more information, visit
    http://ccr.cancer.gov/careers/traco.asp

    TRACO: Genomics and Case Report

  • From Transcript to Target: Integrating RNAi into the Analysis of Cancer Gene Function and Anti-cancer Drug Development (NIH-Only)
    • - Caplen, N.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : NCI CCR Grand Rounds (NIH Only)
    Dr. Caplen obtained her Ph.D. from the University of London (Kings College Hospital Medical School) for studies on the genetics of type I diabetes and its complications. Dr. Caplens postdoctoral training began at St. Marys Hospital Medical School, Imperial College, where she focused on the development of gene therapy approaches for cystic fibrosis (CF) during which she was involved in some of the first pre-clinical and clinical studies of cationic lipid mediated gene therapy for CF. In 1996, Dr. Caplen came to the National Human Genome Research Institute (NHGRI) at NIH as a visiting fellow, where she initially conducted studies investigating hybrid viral vector systems for the delivery of genes. It was while at NHGRI that Dr. Caplen developed a research interest in the newly identified gene silencing mechanism, RNA interference (RNAi) leading to her studies that help establish the presence of RNAi in mammalian cells. Dr. Caplen joined CCR, NCI, in 2004 as a senior scientist, where she heads the Gene Silencing Section initially within the CCR Office of Science and Technology Partnerships and more recently within the Genetics Branch.

    NCI???s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link:
    http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx

    From Transcript to Target: Integrating RNAi into the Analysis of Cancer Gene Function and Anti-cancer Drug Development (NIH-Only)

  • FDA-NCI Workshop on Therapeutic Cancer Vaccines
    • - FDA-NCI Workshop on Therapeutic Cancer Vaccines
      National Cancer Institute (U.S.) (2010/11/18)
    • - Category : Conferences
    FDA and NCI are holding a public workshop intended to facilitate the development of safe and effective cancer vaccine by optimizing early phase clinical trials based on lessons learned from completed Phase III studies.

    In this workshop, the role of randomized Phase II clinical trials and adaptive study designs will be discussed. Furthermore, the workshop will emphasize the importance of monitoring immune responses in early phase trials in order to optimize immunological therapies and incorporating pretreatment biomarkers in early phase clinical studies that could predict the effect of specific treatment for patients (predictive biomarkers) in order to identify a population likely to benefit.

    For more information, visit
    http://web.ncifcrf.gov/events/cancervaccine/default.asp

    FDA-NCI Workshop on Therapeutic Cancer Vaccines

  • Stress and Health: From Molecules to Societies
    • - Sapolsky, Robert M.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Wednesday Afternoon Lectures
    Few Westernized humans are likely to die of scarlet fever, malaria or malnutrition. Instead, we live well enough and long enough to succumb to the diseases of slow degeneration. It is increasingly recognized that a large percentage of such diseases can be caused by or worsened by stress. This lecture approaches the subject of stress and health from two very different perspectives.

    To learn more about Dr. Sapolsky, visit
    http://wals.od.nih.gov/2009-2010/october2009x.html

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Stress and Health: From Molecules to Societies

  • CC Grand Rounds: Novel Treatment for Myelodysplasia
    • - Sloand, Elaine M.
      National Institutes of Health (U.S.). Clinical Center. (2010/11/18)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Grand Rounds

    Elaine M. Sloand, MD
    Senior Investigator, Hematology Branch, NHLBI

    Matthew Olnes, MD, PhD
    Clinical Fellow, Hematology Branch, NHLBI
    Staff Clinician, Center for Human Immunology and Inflammation (CHI)

    For more information, visit
    http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: Novel Treatment for Myelodysplasia

  • Developing and Implementing Lymphoi Stress Surveillance
    • - Hayday, Adrian.
      National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18)
    • - Category : Immunology
    Adrian Hayday is Professor and Head of the Division of Immunology, Infection & Inflammatory Diseases in Kings College London Medical School. A graduate of Cambridge University, Adrian earned his PhD from Imperial College London and did a postdoctoral fellowship at MIT with Susumu Tonegawa where he studied the basis for chromosomal translocations and was an early pioneer in cloning and studying TCR genes, particularly the TCRgamma chain, which sparked his longterm interest in the differentiation and biological function of gamma-delta T cells. A few years ago, Adrian developed an intriguing and novel picture of gamma-delta T cell and Treg development in the thymus, referred to as trans-differentiation. More recently, he has identified a central role for gamma-delta T cells in the rapid response to microbial infection and other inflammatory stresses which he refers to as lymphoid stress-surveillance and which is potentially amenable to clinical manipulation for tumor immunology and autoimmunity. Adrian Hayday is a refreshingly original thinker and highly innovative scientist, as well as an excellent speaker.

    The Immunology Interest Group

    Developing and Implementing Lymphoi Stress Surveillance

  • Study Design, Randomization, Placebos - 2009 (Session 6)
    • - Robert Truog and Frank Miller (2010/11/18)
    • - Category : Bioethics
    Ethical and Regulatory Aspects of Clinical Research

    Department of Clinical Bioethics

    This course is designed to provide a historical context for research regulations and to help researchers and others working in human subject research gain insights and skills into the development of research protocols and their ethical implementation.

    Objectives of the Course:

    To learn the codes, declarations, and other documents that govern the ethical conduct of human subject research; review the critical elements of informed consent and their implementation in actual informed consent documents for clinical research; explore controversial issues relating to human subject research, including Phase I research, randomization, children in research, international research, etc; review the purpose if IRBs and provide IRB-like experience in reviewing research protocols; understand the experience of human subjects who have participated in research protocols.

    8:30-9:15???????? ???? ?????????????????????? Ethics of Randomized Clinical Trials: Clinical Equipoise ??????????????????????

    ?????????????????????????????????????????????????????????????????????? Robert Truog, M.D. ????????

    Professor of Anesthesiology & Medical Ethics

    Harvard Medical School

     

    9:15-9:25???????????????????????????????? ???? Discussion

     

    9:25- 10:10 ?????????????????????????????? Ethics of Placebo Controlled Trials ??

    ?????????????????????????????????????????????????????????????????????? Frank Miller, Ph.D.

    Department of Bioethics CC/NIH ??

     

    10:10- 10:20???????????????????????????? Discussion

     

    10:20- 10:35???????????????????????????? Break

     

    10:35- 11:30???????????? ?????????????? Participant panel

    For more information, visit
    http://www.bioethics.nih.gov

    Study Design, Randomization, Placebos - 2009 (Session 6)