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  • NIH STEP Forum: Nuts-and-Bolts of Community Engagement in Research (NIH-Only)
    • - Sponsored by the Office of Communications and Public Liaison (2010/11/18)
    • - Category : STEP (HHS Only)
    Community engagement in research enhances the overall effectiveness and impact of biomedical and behavioral research efforts, providing mutually beneficial outcomes for researchers, patients, and communities involved. Geared toward NIH extramural and intramural research program and outreach staff, this session will introduce participants to five core principles of community-engaged research through presentations emphasizing methodology, theoretical frameworks, and evaluation techniques used in effective community engagement approaches. Presenters will also discuss communication and facilitation skills used to develop connections and build relationships with communities. Dr. Raynard Kington will make the opening remarks for the session, which was inspired by comments from the NIH Directors Council of Public Representatives.

    The forum is inspired by the NIH Director???s Council of Public Representatives (COPR) recommendations on community-engaged research and geared toward NIH extramural and intramural research, program, and outreach staff. Dr. Raynard Kington, NIH Principal Deputy Director will give opening remarks. The agenda also includes an overview of community-engaged research, presentation of COPR recommendations, case studies of best practices and practical application of principles referenced in the COPR recommendations, and an open panel discussion.

    For more information, visit http://step.nih.gov/oer/training/step/step.htm

    NIH STEP Forum: Nuts-and-Bolts of Community Engagement in Research (NIH-Only)

  • mHealth Summit (Day 1)
    • - MHealth Summit
      Foundation for the National Institutes of Health. (2010/11/18)
    • - Category : Conferences
    Summit Mission
    The mission of the mHealth Summit is to explore the use of mobile technologies to improve public health, particularly regarding underserved populations; health research, training, and education applications; and delivery systems, in the U.S. and around the world.

    Summit Overview
    Mobile technologies have the potential to transform global health care on many fronts, from research and diagnostics to training and preventative interventions. Targeting experts from such diverse fields as medical research, software design, clinical health care, hardware manufacture and network transmission, the summit hopes to spur development and deployment of innovative, practical, affordable and effective solutions to health challenges in underserved and resource-poor populations.
    In addition to reviewing current tools and research from a wide spectrum of stakeholders, the summit will foster inter-disciplinary collaboration that could identify entirely new opportunities that team existing mobile-industry companies with emerging public health facilitators.

    Summit Goals
  • Assess current policies regarding mobile health technologies and their use in reducing or eliminating domestic and global health disparities.
  • Build a bridge between biomedical researchers and mobile technology experts to identify mHealth solutions.
  • Foster integration of mobile and medical technology to improve delivery of health care to underserved populations.
  • Discuss and craft a vision for mHealth technologies moving forward.
  • mHealth Summit (Day 1)

  • Gaps (and Gasps!) in Medical-Ethical Reasoning: From Ethical Theory to Medical Practice
    • - Malm, Heidi.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    Good healthcare practice and policy cannot be developed on the basis of scientific evidence alone. Also essential are value-laden or ???moral??? judgments which, for example, prioritize some endpoints over others (e.g., quality of life over quantity of life), and sanction some means of achieving those endpoints but prohibit others (e.g., Is informed consent always necessary? May harm be caused to some in order to prevent greater harm to others?).

    This presentation will first demonstrate how the methods that contemporary ethical theorists use to develop, test and apply moral judgments are similar to the methods that medical scientists use to develop, test and apply their evidence. It will then examine several flaws, cognitive biases, and under-appreciated distinctions within medical-ethical reasoning (each of which has a sibling in scientific reasoning) that give rise to gaps between ethical theory and medical practice. Throughout the discussion, preference will be given to medical-ethical issues involving the prevention of harm, including cancer prevention, public health, and pandemic planning.

    About Heidi Malm, Ph.D.

    Heidi Malm is Professor of Philosophy at Loyola University Chicago. Her areas of specialization include ethical theory, bioethics and the philosophy of law. Her academic research focuses on ethical issues involving autonomy and the prevention of harm, with a current focus on issues within the field of preventive medicine and law. She has published on the topics of killing vs. letting die, legal paternalism, medical screening, bad Samaritan laws and the duty to aid, consent and the law on rape, and surrogate motherhood, and her articles have appeared in a variety of high-profile journals including Ethics, The Hastings Center Report, Law and Philosophy, American Journal of Bioethics and Philosophy & Public Affairs. A recent article Dr. Malm co-authored, Ethics, Pandemics, and the Duty to Treat, appeared in the American Journal of Bioethics (2008), received much fanfare and is frequently cited. The article addresses the very timely topic of the healthcare workers duty to treat in times of pandemics; matters of interest to academicians and practitioners in medicine, law, philosophy, public health, and government.

    Dr. Malm also works on issues related to ethics and preventive medicine, in particular, ethical issues related to medical screening for diseases such as cancer, as well as the furthering of evidence-based medicine. She has served as the bioethicist on several committees for the National Institutes of Health and has been an invited speaker at numerous schools of medicine and public health, including Harvard, Johns Hopkins, and Northwestern.

    Medicine: Mind the Gap
    Bridging the Gap Between Evidence and Practice
    An NIH Seminar Series

    Bridging the gap between evidence and practice
    The Medicine: Mind the Gap series will explore a wide range of issues at the intersection of research, evidence, and clinical practice???especially areas in which conventional wisdom may lead us astray. From the role of advocacy organizations in medical research and policy, to off-label drug use, to the effectiveness of continuing medical education, the seminar series will aim to engage the NIH community in thought-provoking discussions to challenge what we think we know and to think critically about our role in today???s research environment.

    Presented by the NIH Consensus Development Program

    Gaps (and Gasps!) in Medical-Ethical Reasoning: From Ethical Theory to Medical Practice

  • Chronic Fatigue Syndrome Advisory Committee Meeting (CFSAC) - Day 1
    • - HHS Office on Womens Health (OWH) (2010/11/18)
    • - Category : Chronic Fatigue Syndrome Advisory Committee
    The Chronic Fatigue Syndrome Advisory Committee (CFSAC) provides advice and recommendations to the Secretary of Health and Human Services via the Assistant Secretary for Health of the U.S. Department of Health and Human Services on issues related to chronic fatigue syndrome (CFS).

    Wanda K. Jones, DrPH
    CFSAC Designated Federal Official
    Deputy Assistant Secretary for Health ??? Women???s Health

    For more information, visit
    http://www.hhs.gov/advcomcfs

    Chronic Fatigue Syndrome Advisory Committee Meeting (CFSAC) - Day 1

  • mHealth Summit (Day 2)
    • - MHealth Summit
      Foundation for the National Institutes of Health. (2010/11/18)
    • - Category : Conferences
    Summit Mission
    The mission of the mHealth Summit is to explore the use of mobile technologies to improve public health, particularly regarding underserved populations; health research, training, and education applications; and delivery systems, in the U.S. and around the world.

    Summit Overview
    Mobile technologies have the potential to transform global health care on many fronts, from research and diagnostics to training and preventative interventions. Targeting experts from such diverse fields as medical research, software design, clinical health care, hardware manufacture and network transmission, the summit hopes to spur development and deployment of innovative, practical, affordable and effective solutions to health challenges in underserved and resource-poor populations.
    In addition to reviewing current tools and research from a wide spectrum of stakeholders, the summit will foster inter-disciplinary collaboration that could identify entirely new opportunities that team existing mobile-industry companies with emerging public health facilitators.

    Summit Goals
  • Assess current policies regarding mobile health technologies and their use in reducing or eliminating domestic and global health disparities.
  • Build a bridge between biomedical researchers and mobile technology experts to identify mHealth solutions.
  • Foster integration of mobile and medical technology to improve delivery of health care to underserved populations.
  • Discuss and craft a vision for mHealth technologies moving forward.
  • mHealth Summit (Day 2)

  • Widening the Use of Electronic Health Record Data for Research
    • - National Center for Research Resources (U.S.) (2010/11/18)
    • - Category : Conferences
    Electronic records have yet to be broadly implemented nationally but there are large national efforts underway to address this lag in technology adoption. Concurrently, leading adopters of health information technology are looking beyond their implementation investment towards the value that might be derived from the secondary applications of clinical data obtained during the course of healthcare. This symposium will illustrate the challenges, pitfalls and key informers of success in the secondary application of electronic healthcare data using examples from comparative effectiveness research, pharmacovigilance, public health, and health disparities research. It will identify challenge areas of mutual interest; roadblocks that can be addressed in the short term; and successful roadmaps.

    For more information, visit http://palladianpartners.com/e-health/

    Widening the Use of Electronic Health Record Data for Research

  • Chronic Fatigue Syndrome Advisory Committee Meeting (CFSAC) - Day 2
    • - HHS Office on Womens Health (OWH) (2010/11/18)
    • - Category : Chronic Fatigue Syndrome Advisory Committee
    The Chronic Fatigue Syndrome Advisory Committee (CFSAC) provides advice and recommendations to the Secretary of Health and Human Services via the Assistant Secretary for Health of the U.S. Department of Health and Human Services on issues related to chronic fatigue syndrome (CFS).

    Wanda K. Jones, DrPH
    CFSAC Designated Federal Official
    Deputy Assistant Secretary for Health ??? Women???s Health

    For more information, visit
    http://www.hhs.gov/advcomcfs

    Chronic Fatigue Syndrome Advisory Committee Meeting (CFSAC) - Day 2

  • NIH Directors Council of Public Representatives - October 2009
    • - National Institutes of Health (U.S.). Directors Council of Public Representatives. (2010/11/18)
    • - Category : NIH Directors Council of Public Representatives
    The Directors Council of Public Representatives (COPR) is a federal advisory committee made up of members of the public, who advise the National Institutes of Health (NIH) Director on issues related to public participation in NIH activities, outreach efforts, and other matters of public interest.

    For more information, visit
    http://copr.nih.gov

    NIH Directors Council of Public Representatives - October 2009

  • Sounds in silence: How the ear initiates activity in the auditory system before hearing begins
    • - Bergles, Dwight.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Neuroscience
    Dr. Bergles lab is interested in understanding the mechanisms by which neurons and glial cells interact to support normal communication in the nervous system. Neurons transmit information at specialized synaptic junctions, points of contact where action potentials elicit the release of a chemical neurotransmitter. Neurotransmission at excitatory synapses involves the vesicular release of glutamate, diffusion and binding of glutamate to various receptors, and uptake of glutamate by transporters. Transporters are critical for ensuring that receptors are available to bind glutamate during subsequent release events, as well as for limiting receptor activation so that excitotoxic damage does not occur. Transporters may also shape the activation of receptors on a more rapid time scale during synaptic transmission. Because transporters play a critical role in glutamate homeostasis, understanding their function has relevance for numerous afflictions, such as stroke, epilepsies, and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS).

    A related area of research in our lab involves the study of these pathways and their roles in development and synaptic physiology. The recent discovery of glutamatergic synapses between pyramidal neurons and oligodendrocyte precursor cells (OPCs) in the hippocampus has raised many questions about the involvement of these neuro-glial junctions in regulating OPC differentiation, as well as the role of these progenitor cells in hippocampal physiology. They are currently studying these neuro-glial synapses though whole-cell recordings from identified OPCs, and dual pyramidal neuron-OPC recordings in hippocampal slices. As glutamate receptor signaling may regulate oligodendrocyte development and thus myelination, these studies may lead to new approaches for stimulating re-myelination after injury or disease.

    For more information see our website - http://neuroseries.info.nih.gov

    Sounds in silence: How the ear initiates activity in the auditory system before hearing begins

  • Non-invasive Methods for Measuring Stress and Immune Biomarkers to Monitor CAM Interventions: Development and Challenges
    • - Sternberg, Esther M.
      National Center for Complementary and Alternative Medicine (U.S.) (2010/11/18)
    • - Category : NCCAM Lectures
    A major challenge to conducting rigorous studies to evaluate the efficacy and mechanisms of CAM interventions is the need for sensitive methods for measurement and detection of physiological and molecular outcome measures, which can be applied to subjects with minimal stress and distress. In this lecture, Dr. Sternberg will describe the development of a method to measure neural and immune biomarkers in sweat as one potential approach, and will also touch on other methods, such as heart rate variability, which can be applied under selected conditions to achieve these goals. Case studies using these approaches will be described.

    The National Center for Complementary and Alternative Medicine presents the Complementary and Integrative Medicine Consult Service lecture series. The series provides NIH Clinical Center staff with the opportunity to learn more about how the integration of various complementary and alternative medicine treatments can affect approaches into the research and practice of medicine.

    More information on the Complementary and Integrative Medicine Consult Service is located at http://nccam.nih.gov/consultservice/

    Non-invasive Methods for Measuring Stress and Immune Biomarkers to Monitor CAM Interventions: Development and Challenges

  • Academic CAT Track: Job Interviews
    • - Sponsored by the NIH Office of Intramural Training & Education (2010/11/18)
    • - Category : Career Development/OITE
    After the application packet, the job interview is the next major hurdle to securing a position. In this workshop, learn the "dos and donts" of academic job interviewing and hear a perspective on what interview committees like to see.

    Topics that will be covered:
    • What to expect
    • How to prepare
    • Types of questions to expect
    • Questions to ask
    • What to do after the interview
    Speaker:
    Sharon Milgram, PhD, Director of the NIH Office of Intramural Training and Education

    Academic CAT Track: Job Interviews

  • TRACO: Health Disparities and Epidemiology
    • - S. Ambs and N. Caporaso (2010/11/18)
    • - Category : TRACO
    For more information, visit
    http://ccr.cancer.gov/careers/traco.asp

    TRACO: Health Disparities and Epidemiology

  • NCI Board of Scientific Advisors - November 2009 (Day 1)
    • - NCI Board of Scientific Advisors. Meeting (2010/11/18)
    • - Category : NCI Board of Scientific Advisors
    Provides scientific advice on a wide variety of matters concerning scientific program policy, progress, and future direction of the NCIs extramural research programs, and concept review of extramural program initiatives.

    For more information, visit
    http://deainfo.nci.nih.gov/advisory/bsa.htm

    NCI Board of Scientific Advisors - November 2009 (Day 1)

  • Synaptic and Neuronal Mechanisms of Learned and Innate Fear
    • - Bolshakov, Vadim.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    Candidate for Tenure Track Investigator in the NIMH-DIRP Genes, Cognition and Psychosis Program

    Synaptic and Neuronal Mechanisms of Learned and Innate Fear

  • A Cytokine Interest Group Symposium on: The Interleukin-1 Cytokine Family
    • - Cytokine Interest Group Symposium on the Interleukin-1 Cytokine Family (2010/11/18)
    • - Category : Conferences
    Interleukin-1, the first named Interleukin, is experiencing a true renaissance and many recent studies have uncovered yet new pivotal roles of this cytokine family in the regulation of inflammation and tissue homeostasis. This Symposium is offering presentations on new emerging aspects of the Interleukin-1 family biology by extramural and intramural investigators, some of which have been among the pioneers of this field of research.

    A Cytokine Interest Group Symposium on: The Interleukin-1 Cytokine Family

  • NCI Board of Scientific Advisors - November 2009 (Day 2)
    • - NCI Board of Scientific Advisors. Meeting (2010/11/18)
    • - Category : NCI Board of Scientific Advisors
    Provides scientific advice on a wide variety of matters concerning scientific program policy, progress, and future direction of the NCIs extramural research programs, and concept review of extramural program initiatives.

    For more information, visit
    http://deainfo.nci.nih.gov/advisory/bsa.htm

    NCI Board of Scientific Advisors - November 2009 (Day 2)

  • Ethical Issues in International Research - 2009 (Session 7)
    • - Alan Wertheimer, Joe Millum and Seema Shah (2010/11/18)
    • - Category : Bioethics
    Ethical and Regulatory Aspects of Clinical Research

    Department of Clinical Bioethics

    This course is designed to provide a historical context for research regulations and to help researchers and others working in human subject research gain insights and skills into the development of research protocols and their ethical implementation.

    Objectives of the Course:

    To learn the codes, declarations, and other documents that govern the ethical conduct of human subject research; review the critical elements of informed consent and their implementation in actual informed consent documents for clinical research; explore controversial issues relating to human subject research, including Phase I research, randomization, children in research, international research, etc; review the purpose if IRBs and provide IRB-like experience in reviewing research protocols; understand the experience of human subjects who have participated in research protocols.

    8:30- 9:10???????????????????????????????????? Exploitation??

    Alan Wertheimer PhD

    ?????????????????????????????????????????????????????????????????????? NIH Clinical Center Dept of Bioethics

     

    9:10-9:20?????????????????????????????????????? Discussion

     

    9:20- 10:05 ?????????????????????????????? Special issues in international research

    ?????????????????????????????????????????????????????????????????????? Joe Millum PhD

    ?? ?????????????????????????????????????????????????????????????????? NIH Clinical Center Dept of Bioethics

     

    10:05-10:15?????????????????????????????? Discussion

     

    10:15- 10:25 ?????????????????????????? Break

     

    10:25- 11:10???????????????????????????? International research ethics: Informed consent and post trial considerations

    Seema Shah JD

    NIH Clinical Center Dept of Bioethics??????????????????

     

    11:10- 11:20???????????????????????????? Discussion

     

    11:20- 11:30???????????????????????????? Post tests and evaluations



    For more information, visit
    http://www.bioethics.nih.gov

    Ethical Issues in International Research - 2009 (Session 7)

  • NIH American Indian Alaska Native Heritage Month Observance
    • - Nez Henderson, Patricia.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    The Ninth Annual NIH American Indian and Alaska Native Heritage Month Program will be held on Wednesday, November 4, 2009 from 11:00 ??? 12:00 p.m. at the Natcher Conference Center, Building 45, with a poster session to follow.

    This years program will feature a scientific speaker and cultural performance. Patricia Nez Henderson, MD, MPH, will speak on the topic Indian Country Tobacco-free & Smokefree Policy: The Navajo Experience. Dr. Henderson is Vice President of the Black Hills Center for American Indian Health, a non-profit health organization in Rapid City, South Dakota. Dr. Henderson is a member of the Din챕 (Navajo) tribe.

    The cultural performance for the program will feature the dance troupe, Red Crooked Sky, a collaborative mix of American Indians cultivating and promoting positive cultural awareness through traditional and contemporary dance.

    This event is co-sponsored by the NIH American Indian/Alaska Native Employee Council (AIANEC), the NIH Office of Equal Opportunity and Diversity Management (OEODM) and the NIH John E. Fogarty International Center (FIC).

    NIH American Indian Alaska Native Heritage Month Observance

  • Pharmocogenetics, Clinical Avatars and Predictions of Personalized Medicine
    • - Tonellato, Peter J.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    NLM Informatics Lecture Series

    Dr. Tonellato presents a general approach, mathematical model and computational method to predict clinical efficacy of genetic discoveries using ???clinical avatars??? to conduct simulations of the effect of genotypes on risk, diagnosis and treatment. Clinical avatars are individual medical data records produced from a stochastic model and statistical parameters developed to reflect actual patient populations. The approach is used to detect differences between predictions of two warfarin dosing prediction algorithms applied to several representative patient populations (US general, African American, Asian). Clinical variables (clinical, prescription, and genetic) used in the model were derived from examination of published warfarin prediction and decision support algorithms. Clinical avatars are then produced with variables and population means, variances and dependencies consistent with those found in the literature. Simulations demonstrate strengths and weaknesses of the dosing algorithms depend on population characteristics, size and genetic frequencies. All modeling, computations and simulations are conducted on our cloud computing environment. Examples of the strategy, methods, and simulations in other areas of personalized medicine such as cancer risk prediction will be discussed.

    Acrobat Slides

    Pharmocogenetics, Clinical Avatars and Predictions of Personalized Medicine

  • Learned and Cognitive Controls of Ingestive Behavior
    • - Benoit, Stephen C.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Brain & Obesity
    A Brain and Obesity Intramural Lecture Series talk by Dr. Stephen C. Benoit, Ph.D.

    Learned and Cognitive Controls of Ingestive Behavior