전체 8345
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- Immunity, Inflammation and Cancer - Day 1 (NIH-Only)
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- - NCI/CCR (2010/11/18)
- - Category : NIH Only
- This NCI sponsored conference will host international leaders in the field of cancer and inflammation and should provide an exciting forum for discussion and debate on the state of current understanding of this field. Sessions will include: 1) Cancer Immunity and Immunosurveillance; 2) Cancer and Inflammation; 3) The Microbiome Role in Immunity, Tissue Homeostasis and Cancer; and 4) The Tumor Microenvironment. The target audience for this conference is researchers interested in the latest developments in the role of inflammation in development and progression of cancer.
http://web.ncifcrf.gov/events/cancerinflammation/2010/default.asp
Immunity, Inflammation and Cancer - Day 1 (NIH-Only)
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- Choosing & Applying to Graduate School
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- - Sharon L. Milgram, PhD, Director of OITE (2010/11/18)
- - Category : Career Development/OITE
- A successful graduate career depends on finding a good match between you and your program. This workshop will discuss factors to consider when you think about picking a graduate program and school. This event is appropriate for: Postbaccalaureates.
Choosing & Applying to Graduate School
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- Immunity, Inflammation and Cancer - Day 2 (NIH-Only)
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- - NCI/CCR (2010/11/18)
- - Category : NIH Only
- This NCI sponsored conference will host international leaders in the field of cancer and inflammation and should provide an exciting forum for discussion and debate on the state of current understanding of this field. Sessions will include: 1) Cancer Immunity and Immunosurveillance; 2) Cancer and Inflammation; 3) The Microbiome Role in Immunity, Tissue Homeostasis and Cancer; and 4) The Tumor Microenvironment. The target audience for this conference is researchers interested in the latest developments in the role of inflammation in development and progression of cancer.
http://web.ncifcrf.gov/events/cancerinflammation/2010/default.asp
Immunity, Inflammation and Cancer - Day 2 (NIH-Only)
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- Translational Health Disparities Course: Module 5 - Health Disparities Research in Racial and Ethnic Minority Populations
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- - National Institute on Minority Health and Health Disparities (2010/11/18)
- - Category : Health Disparities
- Chapters: After attending this module, participants will be able to: describe and understand the health disparities in racial/ethnic minority populations, with a focus on the social, economic, behavioral, and physical and environmental factors that underlie them, and understand the role of prevention, early detection, screening and access to quality care.
Translational Health Disparities Course: Module 5 - Health Disparities Research in Racial and Ethnic Minority Populations
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- Translational Health Disparities Course: Module 6 - Rural Health Disparities, Child and Adolescent Health, and Immigrant Health Disparities
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- - National Institute on Minority Health and Health Disparities (2010/11/18)
- - Category : Health Disparities
- Chapters: After attending this module, participants will be able to: describe and understand health problems experienced by rural populations, children and adolescents, and immigrant groups, the social, economic, and cultural factors that influence the health status of these groups.
Translational Health Disparities Course: Module 6 - Rural Health Disparities, Child and Adolescent Health, and Immigrant Health Disparities
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- 20th Anniversary of the Office of research on womens Health
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- - Office of research on womens Health (2010/11/18)
- - Category : Womens Health
- All day Scientific symposium and reception
20th Anniversary of the Office of research on womens Health
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- National Advisory Dental and Craniofacial Research Council - September 2010
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- - Dr. Alicia Dombroski (2010/11/18)
- - Category : National Advisory Dental and Craniofacial Research Council
- The mission of the National Institute of Dental and Craniofacial Research (NIDCR) includes the support of basic, clinical and translational research as well as the support of research training and the development of research careers. To help achieve the goals of the NIDCR, the National Advisory Dental and Craniofacial Research Council (NADCRC) has the responsibility of advising, consulting with and making recommendations to the Secretary, DHHS, and the Director, NIDCR, on matters relating to the directions of research, research support, training and career development supported by the Institute. Included in this responsibility is the conduct of the secondary review of research grant applications with a focus on NIDCR scientific program priorities and program balance as well as the conduct of research by the Division of Intramural Research, NIDCR.
National Advisory Dental and Craniofacial Research Council - September 2010
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- Predictions for Visual Coding and Performance from the Statistical Properties of Natural Scenes
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- - Wilson S. Geisler, PhD, University of Texas at Austin (2010/11/18)
- - Category : Neuroscience
- Research in Dr. Geislers lab is directed at a wide range of topics in human, monkey and machine vision. Many of the current and recent studies are cast within the framework of ？？？natural systems analysis,？？？ which consists of several components: (i) identify specific natural tasks, (ii) measure the natural scene statistics relevant to performing the tasks, (iii) determine how to optimally use the natural scene statistics to perform the tasks, and (iv) use the first three components to formulate principled hypotheses and test them in behavioral or neurophysiological experiments. Topics currently of particular interest include perceptual grouping, visual search with eye movements, encoding and decoding of neural population responses in retina and visual cortex, defocus estimation, and target detection in the visual periphery. The research is supported primarily with grants from the National Eye Institute.
NIH Neuroscience Seminar Series
Predictions for Visual Coding and Performance from the Statistical Properties of Natural Scenes
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- Working and Living in a Global Community (NIH Only)
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- - Rajendra Pillai (2010/11/18)
- - Category : NIH Only
- Working with colleagues from around the world is a great opportunity to learn about other cultures. But developing relationships with people from many backgrounds can sometimes seem challenging. This presentation aims to increase inter-cultural understanding in order to help people work more effectively with colleagues of many different backgrounds. The target audience includes people from the US, those who have been in the US for years, and those who have arrived more recently, anyone who wants to learn more about understanding others. Topics covered include non-verbal communication, speech patterns, and formation of perceptions.
Working and Living in a Global Community (NIH Only)
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- TRACO: Metastasis and Health Disparities
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- - K. Hunter and S. Ambs (2010/11/18)
- - Category : TRACO
- For more information, visit
http://ccr.cancer.gov/careers/traco.asp
TRACO: Metastasis and Health Disparities
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- Translational Health Disparities Course: Module 7 - Community-based Participatory Research
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- - National Institute on Minority Health and Health Disparities (2010/11/18)
- - Category : Health Disparities
- After attending this module, participants will have knowledge of: the key principles and the importance of community-based participatory research and methods for developing CBPR partnerships and securing long-term support and funding to sustain them. The role of lay health promoter interventions in CBPR and clinical interventions will be discussed.
Translational Health Disparities Course: Module 7 - Community-based Participatory Research
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- VA and CTSA Opportunities for Collaborative Clinical and Translational Science: Enhancing Clinical Phenotyping
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- - Veterans Health Administration (VA) and Clinical and Translational Research Awards (CTSA) Meeting (2010/11/18)
- - Category : Conferences
- A common goal of translational science is better understanding of disease susceptibilities and mechanisms. Evolving approaches that take advantage of electronic health records, biorepositories and genotyping will create new opportunities for clinical phenotyping.
Meeting presentations will describe resources such as a central institutional review board (IRB), informatics and the clinical research pharmacy that the Veterans Health Administration has put in place to support data-intensive studies.
Opportunities for enhanced collaboration among Department of Veterans Affairs and NIHs Clinical and Translational Awards (CTSA) consortium will be discussed. Topics will include electronic health records, genomic and observational research, central IRBs, comparative effectiveness research and synergies with respect to the training environment these provide.
VA and CTSA Opportunities for Collaborative Clinical and Translational Science: Enhancing Clinical Phenotyping
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- Translational Health Disparities Course: Module 8 - Clinical Research and Comparative Effectiveness Research (CER)
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- - National Institute on Minority Health and Health Disparities (2010/11/18)
- - Category : Health Disparities
- After attending this module, participants will be able to: understand the role of comparative effectiveness research, patient-centered care, and where CER will lead us in terms of better patient outcomes, improved population health, and more effective investments in health disparities research.
Translational Health Disparities Course: Module 8 - Clinical Research and Comparative Effectiveness Research (CER)
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- Redox Biology: Introduction and Redox chemistry
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- - T. Moody and D. Wink (2010/11/18)
- - Category : Redox Biology
- For more information, visit
http://ccr.cancer.gov/careers/courses/rb/
Redox Biology: Introduction and Redox chemistry
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- IRB review, Conflicts of Interest and Investigator Perspectives - 2010 (Session 2)
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- - Barbara Karp and Steve Joffe (2010/11/18)
- - Category : Bioethics
- Ethical and Regulatory Aspects of Clinical Research
Course Objectives
By the end of this course, participants will be able to:- Utilize a systematic framework for evaluating the ethics of a clinical research protocol.
- Apply appropriate codes, regulations, and other documents governing the ethical conduct of human subject research to their own research.
- Discuss controversial issues relating to human subject research, including Phase 1 research, randomization, children in research, international research, etc.
- Identify the critical elements of informed consent and strategies for implementing informed consent for clinical research.
- Describe the purpose, function, and challenges of IRBs.
- Appreciate the experience of human subjects who have participated in research protocols.
http://www.bioethics.nih.gov/hsrc/index.shtml
IRB review, Conflicts of Interest and Investigator Perspectives - 2010 (Session 2)
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- Translational Health Disparities Course: Module 9 - Community and Minority Participation in Clinical Research
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- - National Institute on Minority Health and Health Disparities (2010/11/18)
- - Category : Health Disparities
- After attending this module, participants will be able to: describe the issues and challenges faced in achieving community and minority participation in clinical research; issues of inclusion of minorities, women and children as subjects in clinical research, and the scientific and policy implications for health disparities research.
Translational Health Disparities Course: Module 9 - Community and Minority Participation in Clinical Research
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- CC Grand Rounds: Changing Cancer Diagnosis and Treatment Using Geomics
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- - Louis M. Staudt, MD, PhD and Wyndham Wilson, MD, PhD (2010/11/18)
- - Category : Clinical Center Grand Rounds
- Louis M. Staudt, MD, PhD,
Deputy Chief, Metabolism Branch,
Center for Cancer Research, NCI
Wyndham Wilson, MD, PhD,
Senior Investigator and Chief, Lymphoma Therapeutics Section,
Metabolism Branch, Center for Cancer Research, NCI
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
CC Grand Rounds: Changing Cancer Diagnosis and Treatment Using Geomics
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- Translational Health Disparities Course: Module 10 - Translating and Disseminating Scientific Knowledge into Policy and Practice
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- - National Institute on Minority Health and Health Disparities (2010/11/18)
- - Category : Health Disparities
- After attending this module, participants will become familiar with outreach, dissemination and implementation science, and the tools for translating and disseminating scientific knowledge to inform practice and policy.
Translational Health Disparities Course: Module 10 - Translating and Disseminating Scientific Knowledge into Policy and Practice
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- Strategies to Slow the Onset of Blindness in Retinitis Pigmentosa
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- - Dr. Connie Cepko (2010/11/18)
- - Category : Wednesday Afternoon Lectures
- The disease, retinitis pigmentosa (RP), is a blinding illness with genetic etiology. Many different RP genes are expressed in rod photoreceptors exclusively. These are the retinal photoreceptors used for dim light perception, or night vision. Individuals born with these mutations have poor, or no, night vision, but typically have normal daylight and color vision. The rods often deteriorate and die, leading to a complete loss of night vision. Subsequently, the cones, which mediate daylight and color vision, also die, over a period of years, leading to a complete loss of all vision.
We are interested in learning how to stop the progression of RP. To this end, we have investigated the causes of cone death using microarrays and 4 mouse models of RP, looking for changes that are in common across all 4 models at the onset of cone death. Genes that are involved in metabolism were those with the most frequently observed changes. These observations were followed up through several independent assays. The results suggest that cones are starving, potentially leading to their malfunction and death. In addition, we examined the activity of histone deacetylase 4 (HDAC4) in promoting rod survival. When overexpressed in rods, HDAC4 significantly prolonged rod survival, and indirectly, cone survival. This activity required the activity of hypoxia inducible factor 1alpha.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Strategies to Slow the Onset of Blindness in Retinitis Pigmentosa
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- New insights in the establishment of human B cell tolerance
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- - Eric Meffre (2010/11/18)
- - Category : Immunology
- Born in Marseille, France, Eric Meffre was educated at University of Paris, the Pasteur Institute, and the University of Aix-Marseille II, where he received his Ph.D. in Immunology in 1996. During his postdoctoral training with Michel Nussenzweig at The Rockefeller University he made important contributions to the study of human B cells and the antibodies they produce. He initiated the studies that tested the specificity of recombinant antibodies cloned from single B cells. Once he set up his own laboratory at Cornell University, Eric focused his work on mechanisms that regulate B cell tolerance in humans through the analysis of B cells derived from patients with primary immunodeficiencies, such as XLA, IRAK4- and MyD88-deficient patients. He has recently moved to Yale University, were he is currently studying B cell tolerance in patients with CD19, TACI, ICOS, Fas, AID, SAP and FoxP3 deficiencies. He is also interested in the role of NKT and Treg cells in maintaining peripheral B cell tolerance.
The Immunology Interest Group
New insights in the establishment of human B cell tolerance