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  • Practice Based Research Network Technical Conference
    • - National Institute of Dental and Craniofacial Research (U.S.) (2010/03/04)
    • - Category : Special

    Practice Based Research Network Technical Conference

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  • Alcoholism: Variation in Vulnerability - Intermediate Phenotypes and Genetic Mechanisms of Mental Illness
    • - Goldman, David.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Clinical Center Grand Rounds

    Alcoholism: Variation in Vulnerability - Intermediate Phenotypes and Genetic Mechanisms of Mental Illness

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  • Immune Control of HIV: Virus Variability and Vaccine Design
    • - Andrew J. McMichael, Ph.D, FRCP FRS, Oxford University (2010/03/04)
    • - Category : Wednesday Afternoon Lectures

    Dr. Andrew J. McMichael will lecture on "Immune Control of HIV: Virus Variability and Vaccine Design." He is director, Weatherall Institute of Molecular Medicine, professor of molecular medicine, John Radcliffe Hospital, head molecular sciences division, Nuffield department of clinical medicine, Oxford.

    Andrew J. McMichael, Ph.D, FRCP FRS
    Director, Weatherall Institute of Molecular Medicine
    Professor of Molecular Medicine, John Radcliffe Hospital
    Head, Molecular Sciences Division, Nuffield
    Department of Clinical Medicine, Oxford

    The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Immune Control of HIV: Virus Variability and Vaccine Design

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  • The p53 Tumor Suppressor: A Story of Death and Degradation
    • - Karen Vousden, Ph.D., FRS, Beatson Institute for Cancer Research Glasgow, Scotland (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    A Special Tuesday Lecture

    During malignant progression cells are exposed to various types of stress that activate tumor suppressive pathways, thereby preventing further proliferation of the abnormal cell. The p53 protein plays a pivotal role in these responses, in part because stress-induced activation of p53 can lead to the induction of programmed cell death or apoptosis. Most cancer cells only survive because they have acquired genetic alterations that disrupt this apoptotic program. These changes can be thought of as the Achilles heel of cancers, since repairing them would lead to the death of malignant cells, while leaving many normal tissues ??? which are not exposed to the same stress signals - relatively unscathed.

    The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    The p53 Tumor Suppressor: A Story of Death and Degradation

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  • When Too Much Iron Is Bad: Hemochromatosis, the Silent Blood Disease
    • - Leitman, Susan.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Medicine for the Public

    When Too Much Iron Is Bad: Hemochromatosis, the Silent Blood Disease

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  • TRACO: Clinical use of Proteomics
    • - Petricoin, Chip.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : TRACO

    TRACO: Clinical use of Proteomics

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  • Deoxyribonucleoside Kinases in Mitochondrial DNA Depletion
    • - Ann Saada, Shaare Zedek Medical Center, Israel (2010/03/04)
    • - Category : Mitochondria
    The Mitochondria Interest Group (MIG) is an Inter-Institute Interest Group at the National Institutes of Health (NIH), with members from NIH and from around the world! MIG is concerned with all aspects of the mitochondrion and diseases in which the mitochondrion is involved.

    For more information, visit the
    Mitochondria Interest Group (MIG)

    Deoxyribonucleoside Kinases in Mitochondrial DNA Depletion

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  • Tour of Hope at NIH with Lance Armstrong
    • - Lance Armstrong, cancer survivor, President's Cancer Panel, Lance Armstrong Foundation and five-time winner Tour de France (2010/03/04)
    • - Category : Special
    Play Video

    Lance Armstrong, cancer survivor, member of the President's Cancer Panel, founder of the Lance Armstrong Foundation, and five-time winner of the Tour de France, is anchoring a bicycle tour across America to raise awareness of cancer research and the vital importance of clinical trials.

    Lance and a contingent of cyclists will speak to NIH to emphasize the value of clinical trials. NCI is pleased to participate in the NIH salute to the Tour of Hope, which will be a fitting tribute to cancer researchers at NIH and others whose clinical trial work, collaborative arrangements, and cancer communications ultimately work together to provide hope to cancer patients and survivors, their family and friends, and individuals who may be helped through cancer prevention and early detection.

    For information about the Tour of Hope visit
    http://www.tourofhope.org

    Tour of Hope at NIH with Lance Armstrong

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  • Visual Culture and Public Health (Day 2)
    • - National Library of Medicine (U.S.). History of Medicine Division. (2010/03/04)
    • - Category : Conferences

    Visual Culture and Public Health (Day 2)

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  • Visual Culture and Public Health (Day 1)
    • - National Library of Medicine (U.S.). History of Medicine Division. (2010/03/04)
    • - Category : Conferences

    Visual Culture and Public Health (Day 1)

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  • What Makes it Tick? Attempts to Understand the Dynamics of the Ribosome using Cryo-Electron Microscopy
    • - Joachim Frank, Ph.D., New York University (2010/03/04)
    • - Category : Wednesday Afternoon Lectures
    The NIH Director's Wednesday Afternoon Lecture Series

    Cryo-EM of single particles has become indispensable as a tool for visualizing the dynamics of macromolecular machines. Application of this technique to the ribosome has been particularly fruitful. Several snapshots of the elongation cycle, in the form of three-dimensional cryo-EM density maps, are now available at resolutions in the range of 8 to 15 A. These show the ribosome in different conformations. The largest of those changes involves a "ratchet" rotation of the small subunit relative to the large subunit. By "molding" the static x-ray structure into these density maps, we are now gathering information on the local dynamic rearrangements of RNAs and proteins underlying the global changes.

    What Makes it Tick? Attempts to Understand the Dynamics of the Ribosome using Cryo-Electron Microscopy

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  • Extracting Information from Large Datasets
    • - Brian Luke, Advanced Biomedical Computing Center, SAIC (2010/03/04)
    • - Category : Mass Spectrometry Interest Group of the NCI at Frederick
    Current "-omic" techniques are able to produce large amounts of data for a relatively small number of samples in different disease-states. The goal of on-going investigations at the Advanced Biomedical Computing Center (ABCC) is to identify specific features from these datasets to classify the state of an unknown sample with high sensitivity and selectivity. Unfortunately, the amount of data available for each sample is so large that random noise can be used to separate one class of samples from another with virtually 100% accuracy. Such a numerical model has very good statistics, but very little information content. Our efforts are designed to bridge the gap between purely numerical models and classification models that use key features that may suggest an underlaying biological mechanism.

    For more information, visit the Mass Spectrometry Interest Group of the NCI at Frederick

    Extracting Information from Large Datasets

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  • GMAC: Negotiation Skills for Today's Grants Management Specialist (NIH Only)
    • - Doris Campos-Infantino, Deputy Ombudsman, NIH (2010/03/04)
    • - Category : NIH Only
    Useful Tools for both the Novice and the Experienced

    Speaker:
    Ms. Doris Campos-Infantino
    Deputy Ombudsman
    NIH Office of the Ombudsman
    Center for Cooperative Resolution, et al

    This seminar will teach negotiation skills. Learn how to listen non-defensively, make your point, survive difficult conversations, but conclude with a production resolution for you and others.

    GMAC: Negotiation Skills for Today's Grants Management Specialist (NIH Only)

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  • Demystifying Medicine - Prostatic and other Genito-Urinary Cancers
    • - Linehan, Marston.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Demystifying Medicine

    Demystifying Medicine - Prostatic and other Genito-Urinary Cancers

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  • History of DNA Repair: Chinese Hamster Cells and DNA Repair - a Long-Lasting Affair
    • - Dr. Larry Thompson, Lawrence Livermore National Lab (2010/03/04)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group

    History of DNA Repair: Chinese Hamster Cells and DNA Repair - a Long-Lasting Affair

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  • Banburismus and Brain: A Neural Mechanism for Making Decisions
    • - Shadlen, Michael.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Neuroscience

    Banburismus and Brain: A Neural Mechanism for Making Decisions

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  • GMAC - Effective Use of the Payment Management System for the Grants Manager (NIH Only)
    • - Cathy Anzulis, Lori Burge and Eileen Hyde (2010/03/04)
    • - Category : NIH Only
    A Seminar presented by the GMAC Subcommittee on Training

    Join us for an in-depth discussion of the nuances of the Payment Management System (PMS). During this seminar we will address such questions as: What is the Payment Management System? How does the grantee get funds? How do I use the system to obtain pertinent grantee information? This seminar will also include a discussion of what PMS inquiries are most beneficial to the grant manager when analyzing the grantee's financial history as well as addressing how PMS can be used when considering requests for carryover and analyzing stale obligations.

    For more information, visit
    http://odoerdb2-1.od.nih.gov/gmac/gmac/trs_flyer_20040518.html

    GMAC - Effective Use of the Payment Management System for the Grants Manager (NIH Only)

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  • National Advisory Mental Health Council - May 2004 (NIH Only)
    • - United States. National Advisory Mental Health Council.
      National Institute of Mental Health (U.S.) (2010/03/04)
    • - Category : NIH Only

    National Advisory Mental Health Council - May 2004 (NIH Only)

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  • New Mass Spectral Strategies for Proteomics and Glycomics
    • - Costello, Catherine E.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Proteomics

    New Mass Spectral Strategies for Proteomics and Glycomics

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  • Mission Impossible in T Cell Development
    • - Georgopoulos, Katia.
      National Institutes of Health (U.S.) (2010/03/04)
    • - Category : Immunology

    Mission Impossible in T Cell Development

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