전체 8345
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- Raising the Bar for Publishing the Results of Clinical and Translational Research
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- - Joseph E. Parrillo, MD, Professor and Chairman, Department of Medicine, Cooper Medical School of Rowan University; Chief and Edward D. Viner Chair, Department of Medicine and Director, Cooper Heart Institute, Cooper University Hospital (2012/08/17)
- - Category : Clinical Center Grand Rounds
- CC Grand Rounds for Clinical Fellows
For more information go to http://www.cc.nih.gov/about/news/grcurrent.html
Raising the Bar for Publishing the Results of Clinical and Translational Research
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- NHLBI Town Hall August 2012
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- - Dr. Gary H. Gibbons (2012/08/15)
- - Category : Special
- NHLBIs new director, Dr. Gary H. Gibbons, will address the Institute staff for the first time at this NHLBI town hall. Dr. Gibbons will provide an introduction of himself as well as his vision for the Institute.
NHLBI Town Hall August 2012
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- Bridging the Gap--Overcoming Bottlenecks in the Development of Therapeutics for Infectious Diseases
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- - NIAID (2012/08/12)
- - Category : Conferences
- Workshop to bring together experts in the field of infectious diseases therapeutics development and NIAID investigators to share information and ideas about how to promote and facilitate product development.
Bridging the Gap--Overcoming Bottlenecks in the Development of Therapeutics for Infectious Diseases
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- Cancer Genomes Analysis: Computational Challenges and Approaches
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- - Gad Getz, Ph.D., Director of Cancer Genome Computational Analysis at the Broad Institute of MIT and Harvard (2012/08/11)
- - Category : Special
- Dr. Getz will discuss how the recent revolution in sequencing technologies has enabled comprehensive characterization of many thousands of cancer genomes, for example from The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC). These resulting data pose new computational challenges in detecting the various genomic alterations in the cancer genomes from sequencing data, understanding the mechanisms that create them, and dealing with heterogeneous samples. In addition, he will discuss the greatest challenge is how to introduce these findings to clinical trials and standard practice.
The revolution in sequencing technologies in recent years has enabled comprehensive characterization of many thousands of cancer genomes (e.g. TCGA, ICGC). These data pose new computational challenges in two major categories:- Detecting the various genomic alterations in the cancer genomes from sequencing data, understanding the mechanisms that create them and dealing with heterogeneous samples
- Interpreting the genomic events and distinguishing ones that promote cancer initiation or progression (？？？drivers？？？) vs. ones that have little or no effect on cancer evolution (？？？passengers？？？)
Dr. Getz is the Director of Cancer Genome Computational Analysis at the Broad Institute of MIT and Harvard and serves as a member of an NCI Board of Scientific Advisors？？？ subcommittee with oversight of caBIG？？. He has received many awards and honors including the most recent, the Broad Institute Exceptional Year Award. With his background and expertise in computational biology, he seeks to bring statistical methods to the analysis of genomic data. Dr. Getz is interested in developing novel tools for detecting genomic events from high throughput sequencing data and tools that distinguish ？？？driver？？？ from ？？？passenger？？？ alterations in the cancer genome and by that, identifying novel candidate genes, pathways, and non-coding regions that promote tumorigenesis. As an NCI grantee, he leads a team at a major TCGA genome data analysis center, which automatically analyzes data from multiple centers.
Cancer Genomes Analysis: Computational Challenges and Approaches
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- ConnectMore - Undiagnosed Diseases Program with Dr. Gahl (NIH Only)
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- - Dr. William Gahl (2012/08/11)
- - Category : Human Resources (NIH Only)
- ConnectMore Event Information
OHR will be watching a recent 60 Minutes clip of Dr. Gahl and hearing him speak more about the Undiagnosed Diseases Program at the NIH!
ConnectMore - Undiagnosed Diseases Program with Dr. Gahl (NIH Only)
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- Research in Emergency Settings
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- - Dave Wendler, MA, PhD, Head, Unit on Vulnerable Populations, Department of Bioethics, NIH Clinical Center (2012/08/10)
- - Category : Clinical Center Grand Rounds
- CC Grand Rounds for Clinical Fellows
For more information go to http://www.cc.nih.gov/about/news/grcurrent.html
Research in Emergency Settings
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- Sex Influences on Substance Abuse and Other Brain Disorders: The Burden of Proof has Shifted
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- - Dr. Larry Cahill, University of California, Irvine (2012/08/09)
- - Category : Special
- My research focuses on neural mechanisms of memory formation for emotionally arousing events. Although in the past I have pursued this goal using both animal and human subject models, my current work involves only human subject studies. I employ neuropharmacological, neuropsychological, and brain imaging approaches in these studies. My research suggests that activation of beta-adrenergic receptors and the amygdala in humans are critical for enhanced conscious (declarative) memory associated with emotional arousal. For example, I have found that beta-adrenergic blockade in healthy humans selectively impairs long-term memory for emotionally arousing material. Patients with selective damage to the amygdala show a similar deficit. Furthermore, amnesic patients with intact amygdalae demonstrate enhanced memory for emotional material despite their overall impaired memory performance.
Finally, human brain imaging studies are consistent with the neuropyschological findings in suggesting that amygdala activity in humans is selectively related to memory formation under conditions of emotional arousal.
More recently, our work is showing that sex and cerebral hemisphere constitute twin, interacting influences on brain mechanisms of emotion and memory that can no longer be ignored.
Sex Influences on Substance Abuse and Other Brain Disorders: The Burden of Proof has Shifted
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- Translational Medicine
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- - Jeffrey Hausfeld and Michael Ross, Society of Physician Entrepreneurs (SoPE) (2012/08/09)
- - Category : Special
- Society of Physician Entrepreneurs (SoPE)
Drs. Jeffrey Hausfeld and Michael Ross will present their stories:- How physicians have taken their innovative ideas from opportunities to marketed products
- How they have overcome translational hurdles along the way, and how they have integrated their experiences with their medical training to accelerate their faculty positions, redefine their careers, change their perspectives and leave a bigger footprint
Translational Medicine
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- Medicine: Mind the Gap - Cancer Care: The Patients Role, Palliative Care, and Implications for Health Policy
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- - Amy Berman, R.N., The John A. Hartford Foundation (2012/08/08)
- - Category : Special
- The NIH Medicine: Mind the Gap Seminar Series Presents:
？？？Cancer Care: The Patient？？？s Role, Palliative Care, and Implications for Health Policy
What would you do if you were diagnosed with a life-limiting disease? Ms. Berman will share her experiences from the front row of terminal illness and talk about the role of the patient in establishing the goals of care, the importance of palliation, and recommendations for healthcare policy. This is an opportunity to learn how an activated patient, in partnership with the healthcare team, can play a vital role in achieving the triple aim of better health, better care, and lower costs.
Ms. Berman, R.N., is a senior program officer with The John A. Hartford Foundation. She heads the Foundation？？？s Integrating and Improving Services grants, focusing on the development and dissemination of innovative, cost- effective models of care that improve health outcomes for older adults. Ms. Berman is the program officer responsible for a number of efforts to improve transitions of care as well as the Foundation？？？s work to improve home healthcare delivery and efforts to redesign primary care to better meet the needs of those with multiple chronic diseases. She also directs a number of collaborations with Federal partners. Ms. Berman is responsible for the development of the National League for Nursing？？？s geriatric-focused faculty development effort, Advancing Care Excellence for Seniors. This program provides educational strategies, curricular resources, and case studies used in simulation that enhance the geriatric competence of faculty and students. Ms. Berman developed resources and programs to improve the geriatric expertise of nursing educators and clinicians, and conducted a national survey on gerontological nursing content in baccalaureate programs. Her findings were cited in the Institute of Medicine？？？s report, Retooling for an Aging America: Building the Health Care Workforce. Ms. Berman has served as a Joint Commission on Accreditation of Healthcare Organizations coordinator and an accreditation consultant in performance improvement for a variety of healthcare institutions. She also has served on the New York State Department of Health？？？s Emergency Preparedness Task Force and on the professional advisory boards of healthcare institutions in New York City. Ms. Berman is an appointed member of the Aging Task Force for Healthy People 2020 and Health Resources and Services Administration？？？s Patient Safety Clinical Pharmacy Services Leadership Coordinating Council. She is a member of Academy Health; the Gerontological Society of America; and the Honor Society of Nursing, Sigma Theta Tau.
This seminar is sponsored by the Office of Disease Prevention, Office of Research on Women？？？s Health, and the National Center for Complementary and Alternative Medicine.
The Medicine: Mind the Gap seminar series explores a wide range of issues at the intersection of research, evidence, and clinical practice, especially areas in which conventional wisdom may be misleading. The seminar series aims to engage the National Institutes of Health community in thought-provoking discussions to challenge what we think we know and to think critically about our role in today？？？s research environment. Seminars to date have explored gaps between ethical theory and medical practice, the role of medical evidence in reducing practice variation and controlling costs, and special challenges of ？？？rules of evidence？？？ in translational research.
For more information go to http://prevention.nih.gov/mindthegap/berman.aspx
Medicine: Mind the Gap - Cancer Care: The Patients Role, Palliative Care, and Implications for Health Policy
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- Division of Administration All Managers Meeting - July 2012 (HHS Only)
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- - Assistant Secretary for Administration, E.J. Holland, Jr. (2012/08/07)
- - Category : HHS Only
- Internal meeting for 200+ managers
Division of Administration All Managers Meeting - July 2012 (HHS Only)
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- Innovations in Multi-Level Intervention Research in Latino Communities: Data needs for replication and process implementation
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- - Dr. Alex Ortega, University of California, Los Angeles (2012/08/04)
- - Category : Health Disparities
- NIH Health Disparities Seminar Series
Standards for collecting and reporting data on race, ethnicity, sex, primary language, and disability status help researchers, policy makers, health providers, and advocates identify and address health disparities affecting underserved communities. However, identifying health disparities and effectively targeting and monitoring efforts to address them has been limited by a lack of specificity, uniformity, and quality in data collection and reporting procedures. In his presentation, Dr. Ortega will discuss an intervention to improve the food landscape in East Los Angeles, California, a high-profile Latino community that has been classified as a ？？？food swamp,？？？ with poor access to comprehensive grocery stores and foods recommended as a basis for a healthful diet. This corner store conversion, or market makeover intervention, involves many stakeholders and participants. Dr. Ortega will discuss the process, implementation and impact of this multi-level, community-oriented, trans-disciplinary and transformational intervention.
Dr. Ortega, an epidemiologist and health services researcher, is Professor of Public Health and Psychiatry & Bio-Behavioral Sciences at the University of California, Los Angeles (UCLA). He is Director and Principal Investigator of the UCLA Center for Population Health and Health Disparities, a National Heart, Lung, and Blood Institute-funded Center of Excellence that aims to understand and intervene in cardiovascular disease disparities among Latinos in East Los Angeles. Dr. Ortega received his M.P.H. in epidemiology and biostatistics from Boston University and a Ph.D. in epidemiologic science from the University of Michigan.
Innovations in Multi-Level Intervention Research in Latino Communities: Data needs for replication and process implementation
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- Making the Invisible, Visible - Lecture and Art Challenge
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- - Professor Rebecca Kamen, Artist in Residence and Professor, NOVA (2012/08/04)
- - Category : Special
- Professor Rebecca Kamen, Artist in Residence and Professor, NOVA, will give a lecture:
？？？Making the Invisible, Visible: Discoveries between Art and Science？？？
In this lecture Rebecca will talk about her own work bridging art and science, and share reflections and insights from her time with NIH neuroscientists and students this summer.
Art Challenge displays This will be an informal time to continue the dialog about the bridge between art and science and discuss ways to visualize your research with the artists, faculty and peers.
Artist are encouraged to bring easels or other appropriate equipment to display their work, otherwise art will be displayed on tables around the room.
Complete and ？？？incomplete？？？ art projects are encouraged. An art project is not required for attendance.
Making the Invisible, Visible - Lecture and Art Challenge
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- New Policies and Procedures Related to Newly Proposed Human Subjects Research in Active Awards (HHS Only)
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- - Ann Hardy (2012/08/03)
- - Category : ESA (HHS Only)
- Overview: This training will discuss the implementation of new policy guidance about the need for prior NIH approval for certain changes in the approved involvement of human subjects in on-going awards (change in scope) and for awards that were submitted with the intent to conduct human subjects research but which were not able to provide definitive plans in the application (delayed onset). The new policies are intended to improve the ability of IC extramural staff to appropriately monitor awards that involve human subjects and to make the approach to these more consistent across NIH.
For more information go to http://nih-extramural-intranet.od.nih.gov/nih/training/esa/esa_training_20120731.htm
New Policies and Procedures Related to Newly Proposed Human Subjects Research in Active Awards (HHS Only)
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- Research, Evidence-Based Medicine and the Act of Healing
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- - Richard Colgan, MD, Associate Professor, University of Maryland School of Medicine and Director, Undergraduate Education, Department of Family and Community Medicine (2012/08/03)
- - Category : Clinical Center Grand Rounds
- CC Grand Rounds for Clinical Fellows
For more information go to http://www.cc.nih.gov/about/news/grcurrent/html
Research, Evidence-Based Medicine and the Act of Healing
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- HSHPS Graduate Student Visit
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- - NIH OD OEODM, Hispanic Employment Committee (2012/07/31)
- - Category : Special
- The event features a set of five short presentations given to group of graduate students who are participating in summer internships throughout the DC area. The presenters will convey details about specific programs and career activities to encourage early investigators to seek NIH assistance during their graduate studies and future employment. This event is connected to an on-going collaboration between the NIH Hispanic Employment Committee and the Hispanic Serving Health Professions Schools (HSHPS).
HSHPS Graduate Student Visit
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- Turner v. Rogers Anniversary Forum: Fundamental Fairness and the Ability to Pay in Child Support Proceedings (HHS Only)
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- - Sponsored by Office of Child Support Enforcement and Department of Justice Access to Justice Initiative (2012/07/29)
- - Category : HHS Only
- A panel of experts discusses the critical messages from Turner v. Rogers and its implications for child support. Turner v. Rogers requires states in civil contempt proceedings to provide procedures that ensure a fundamentally fair determination of whether an unrepresented parent is able to comply with a court order to pay child support. This forum includes a discussion of setting realistic child support orders, and other promising practices that avoid the build-up of arrears; explores cost-effective strategies for child support compliance, including alternatives to contempt; and, discusses expanding self-help services and access to justice for unrepresented litigants.
Turner v. Rogers Anniversary Forum: Fundamental Fairness and the Ability to Pay in Child Support Proceedings (HHS Only)
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- Portfolio Analysis Symposium (Day 1)
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- - Office of Portfolio Analysis, DPCPSI, OD (2012/07/28)
- - Category : Conferences
- The Symposium will focus on the use of data-driven methods to inform management of the NIH investment in biomedical research. It will feature internationally renowned experts in portfolio analysis methods and best practices. These experts are from academia, other federal agencies, research organizations, and industry. Attendees will include decision-makers from across NIH, and from other agencies. The Symposium follows from a Portfolio Analysis Workshop, held on February 6, 2012.
For more information go to http://conferences.thehillgroup.com/DPCPSI/PortfolioAnalysisSymposium/index.html
Portfolio Analysis Symposium (Day 1)
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- 2012 Annual Advances in Cancer Prevention Lecture
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- - Cancer Prevention Fellowship Program, National Cancer Institute (2012/07/28)
- - Category : Special
- The purpose is to provide specialized instructions in the principles and practice of cancer prevention and control. Dr. Walter Willett will give the keynote lecture this year. Dr. Willett is Professor of Epidemiology and Nutrition and Chairman of the Department of Nutrition at Harvard School of Public Health and Professor of Medicine at Harvard Medical School.
2012 Annual Advances in Cancer Prevention Lecture
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- Portfolio Analysis Symposium (Day 2)
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- - Office of Portfolio Analysis, DPCPSI, OD (2012/07/27)
- - Category : Conferences
- The Symposium will focus on the use of data-driven methods to inform management of the NIH investment in biomedical research. It will feature internationally renowned experts in portfolio analysis methods and best practices. These experts are from academia, other federal agencies, research organizations, and industry. Attendees will include decision-makers from across NIH, and from other agencies. The Symposium follows from a Portfolio Analysis Workshop, held on February 6, 2012.
For more information go to http://conferences.thehillgroup.com/DPCPSI/PortfolioAnalysisSymposium/index.html
Portfolio Analysis Symposium (Day 2)
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- PSC All Hands - July 2012 (HHS Only)
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- - PSC Leadership (2012/07/27)
- - Category : PSC Programs (HHS Only)
- PSC All Hands meeting to discuss various initiatives
PSC All Hands - July 2012 (HHS Only)