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  • NINDS: Making the Invisible Visible, Lecture and Panel Discussion
    • - Rebecca Kamen, Professor of Art, Northern Virginia Community College (2012/06/29)
    • - Category : Special
    Lecture and Panel Discussion June 26 2:00 pm to 4:00 pm Natcher Conference Center, Balcony B (Building 45)

    Lecture by Rebecca Kamen, Professor of Art, Northern Virginia Community College Title: Patterns: Discoveries Between Art and Science???

    Panel Discussion: ???Engaging the imagination for science and art???

    Panelists:
    Antonina Roll-Mecak, Ph.D., Investigator, Cell Biology and Biophysics Unit, NINDS

    Kenton Swartz, Ph.D., Senior Investigator, Molecular Physiology and Biophysics Section, NINDS

    Joe Mindell, M.D., Ph.D., Senior Investigator, Membrane Transport Biophysics

    NINDS: Making the Invisible Visible, Lecture and Panel Discussion

  • CC Grand Rounds: (1) Understanding the Complexities of Drug Resistance in Cancer (2) Genetic Retinopathies and Treatment Opportunities
    • - (1) Michael M. Gottesman, MD, Deputy Director for Intramural Research, Office of the Director, NIH and Chief, Laboratory of Cell Biology, Center for Cancer Research, NCI (2) Paul A. Sieving, MD, PhD, Director, NEI and Chief, Section on Translational Research for Retinal and Mascular Degeneration, NIDCD (2012/06/29)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds

    Dr. Michael M. Gottesman, deputy director for intramural research, Office of the Director, NIH, and chief, Laboratory of Cell Biology, Center for Cancer Research, will address ???Understanding the Complexities of Drug Resistance in Cancer.???

    Dr. Paul A. Sieving, director, NEI, will present ???Genetic Retinopathies and Treatment Opportunities.???

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: (1) Understanding the Complexities of Drug Resistance in Cancer (2) Genetic Retinopathies and Treatment Opportunities

  • The Joint Meeting of the National Cancer Advisory Board and the NCI Board of Scientific Advisors - May 2012
    • - Various Speakers (2012/06/28)
    • - Category : National Cancer Advisory Board
    The 1st joint meeting of the National Cancer Advisory Board and the NCI Board of Scientific Advisors

    The Joint Meeting of the National Cancer Advisory Board and the NCI Board of Scientific Advisors - May 2012

  • Manhattan Research Briefing: Taking the Pulse Survey Results (HHS Only)
    • - James Avallone, Principal Analyst, Manhattan Research LLC (2012/06/28)
    • - Category : HHS Only
    Manhattan Research LLC will brief the NIH community on the results of its 2012 nationwide survey of physician use of health information technology. The briefing will cover physician use of the Internet, websites, electronic health records, and mobile and tablet devices for practice support, records management, and patient communication.

    Manhattan Research Briefing: Taking the Pulse Survey Results (HHS Only)

  • Omics Integration in Biology and Medicine Workshop (Day 1)
    • - NHLBI and NCI (2012/06/27)
    • - Category : Conferences
    The focus of this meeting will be on the emerging field of integrating disparate omic data from genomics, proteomics, glycomics, etc. in order to better understand key biological processes and also improve clinical practice. Specifically, discussants will consider how to translate the myriad of data available through cutting edge technologies for a single sample onto clinical needs of a population.

    For more information go to http://proteomics.cancer.gov/

    Omics Integration in Biology and Medicine Workshop (Day 1)

  • CC Grand Rounds: New Insights Into the Pathogenesis and Management of Anthrax Sepsis and Septic Shock
    • - (1) Peter Eichacker, MD, Senior Investigator and Head, Critical Care Medicine Section, Critical Care Medicine Department, CC (2) Amisha Barochia, MBBS, Staff Clinician, Laboratory of Asthma and Lung Inflammation, Cardiovasular and Pulmonary Branch, NHLBI (2012/06/27)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: New Insights Into the Pathogenesis and Management of Anthrax Sepsis and Septic Shock

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: New Insights Into the Pathogenesis and Management of Anthrax Sepsis and Septic Shock

  • OHR Telework Online Training - June 2012 (NIH Only)
    • - OHR (2012/06/27)
    • - Category : Human Resources (NIH Only)
    The Office of Human Resources would like to offer training to OHR staff on how to use the Telework Online system. Telework Online is an automated system that allows supervisors and employees to electronically manage telework agreements, from submitting the application to providing approvals.

    OHR Telework Online Training - June 2012 (NIH Only)

  • HHS Lesbian, Gay, Bisexual, and Transgender Pride Month: Improving LGBT Health Across the Lifespan (HHS Only)
    • - Secretary Sebelius, Dr. Carolyn Clancy, Dr. Francis Collins, Kathy Greenlee, Ned Holland, Pamela Hyde, Dr. Mary K. Wakefield (2012/06/24)
    • - Category : HHS Only
    Secretary Sebelius and other HHS senior leaders will discuss the Department???s accomplishments related to improving LGBT health.

    HHS Lesbian, Gay, Bisexual, and Transgender Pride Month: Improving LGBT Health Across the Lifespan (HHS Only)

  • DNA Repair Interest Group: Three Young Investigator Talks
    • - Dr. Sascha Liberti, NIEHS, Dr. Krassi Botcheva, Brookhaven and Dr. Shobhan Gaddameedhi, UNC, Chapel Hill (2012/06/23)
    • - Category : DNA Repair
    DNA Repair Interest Group videoconference

    For more information go to http://sigs.nih.gov/DNA-repair/Pages/default.aspx

    DNA Repair Interest Group: Three Young Investigator Talks

  • Omics Integration in Biology and Medicine Workshop (Day 2)
    • - NHLBI, NCI, and the International Forum of Proteomics (2012/06/23)
    • - Category : Conferences
    The focus of this meeting will be on the emerging field of integrating disparate omic data from genomics, proteomics, glycomics, etc. in order to better understand key biological processes and also improve clinical practice. Specifically, discussants will consider how to translate the myriad of data available through cutting edge technologies for a single sample onto clinical needs of a population.

    For more information go to http://proteomics.cancer.gov/

    Omics Integration in Biology and Medicine Workshop (Day 2)

  • Communicating Possible Harms and Benefits of Treatment and Lifestyle
    • - Professor David Spiegelhalter, OBE, FRS, University of Cambridge (2012/06/23)
    • - Category : Special
    Medicine: Mind the Gap is a lecture series that explores issues at the intersection of research, evidence, and clinical practice???areas in which conventional wisdom may be contradicted by recent evidence. From the role of advocacy organizations in medical research and policy, to off-label drug use, to the effectiveness of continuing medical education, the seminar series will aim to engage the NIH community in thought-provoking discussions to challenge what we think we know and to think critically about our role in today???s research environment.

    There is increasing attention to presenting potential benefits and harms of treatments and lifestyle choices in a balanced and transparent way. Prof. Spiegelhalter will discuss some proposals for how this might be done, focusing on alternative ways in which numbers and graphics may be used, and emphasizing the role of interactive animations and videos. Recent research on public preferences and understanding of different formats strongly suggests that one size does not fit all, and a range of alternative presentations may be appropriate.

    Prof. Spiegelhalter is Winton Professor of the Public Understanding of Risk at the University of Cambridge, where he is also a senior scientist in the Medical Research Council Biostatistics Unit. His background is in medical statistics, particularly the use of Bayesian methods in clinical trials, health technology assessment, and drug safety. He led the statistical team in the Bristol Royal Infirmary Inquiry and also gave evidence to the Shipman Inquiry. Prof. Spiegelhalter has been a consultant to a number of public and private organizations including pharmaceutical companies. In his current post, he leads a small team that is attempting to improve the way in which the quantitative aspects of risk and uncertainty are discussed in society. He was elected a Fellow of the Royal Society in 2005 and awarded an Order of the British Empire in 2006 for services to medical statistics.

    This seminar is sponsored by the Office of Disease Prevention, National Institute on Alcohol Abuse and Alcoholism, National Cancer Institute, Division of Cancer Prevention, and National Heart, Lung, and Blood Institute, Office of Biostatistics Research.

    For more information, visit
    http://prevention.nih.gov/mindthegap/spiegelhalter.aspx

    Communicating Possible Harms and Benefits of Treatment and Lifestyle

  • Genomics of model organisms and human biology: Insights from the modENCODE Project (Day 1)
    • - NHGRI (2012/06/23)
    • - Category : Conferences
    NHGRI will be hosting a special symposium to showcase the findings of the model organism Encyclopedia of DNA Elements (modENCODE) Project and to highlight, for the NIH community, the power of model organisms to inform human biology and disease.

    For more information go to http://www.genome.gov

    Genomics of model organisms and human biology: Insights from the modENCODE Project (Day 1)

  • Translational Bioinformatics: Transforming 300 Billion Points of Data into Diagnostics, Therapeutics, and New Insights into Disease
    • - Atul Butte, M.D., Ph.D., Stanford University (2012/06/23)
    • - Category : Wednesday Afternoon Lectures
    There is an urgent need to translate genome-era discoveries into clinical utility, but the difficulties in making bench-to-bedside translations havent been well described. The nascent field of translational bioinformatics may help. Dr. Buttes lab at Stanford University builds and applies tools that convert more than 300 billion points of molecular, clinical, and epidemiological data (measured by researchers and clinicians over the past decade) into diagnostics, therapeutics, and new insights into disease. Dr. Butte, a bioinformatician and pediatric endocrinologist, will highlight his labs work on using publicly available molecular measurements to find new uses for drugs, discovering new treatable mechanisms of disease in type 2 diabetes, and evaluating patients presenting with whole genomes sequenced.

    The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    Translational Bioinformatics: Transforming 300 Billion Points of Data into Diagnostics, Therapeutics, and New Insights into Disease

  • Genomics of model organisms and human biology: Insights from the modENCODE Project (Day 2)
    • - NHGRI (2012/06/23)
    • - Category : Conferences
    NHGRI will be hosting a special symposium to showcase the findings of the model organism Encyclopedia of DNA Elements (modENCODE) Project and to highlight, for the NIH community, the power of model organisms to inform human biology and disease.

    For more information go to http://www.genome.gov

    Genomics of model organisms and human biology: Insights from the modENCODE Project (Day 2)

  • DOHS Seminar Series - June 2012 (NIH Only)
    • - Trevor Lubbert (2012/06/23)
    • - Category : Occupational Health & Safety Lectures (NIH Only)
    Division of Occupational Health and Safety Seminar Series

    DOHS Seminar Series - June 2012 (NIH Only)

  • 129th Recombinant DNA Advisory Meeting - June 2012
    • - Jacqueline Corrigan-Curay (2012/06/22)
    • - Category : Recombinant DNA Advisory Committee
    National Institutes of Health (NIH) 129th Recombinant DNA Advisory Committee Meeting (RAC), Building 31, Conference Room 10, Bethesda, MD

    For more information go to http://oba.od.nih.gov/rdna_rac/rac_meetings.html

    129th Recombinant DNA Advisory Meeting - June 2012

  • Learning About U.S. Child Obesity from Multiple Longitudinal Surveys
    • - Michael S. Rendall, PhD, University of Maryland (2012/06/21)
    • - Category : BSSR Lecture Series
    BSSR Lecture Series

    A model of child weight-status evolving from birth to early adolescence is first described. This evolution is modeled from children???s having probabilities of transitioning into and out of overweight and obesity between different ages, typically 1 to 3 years apart. To estimate components of this model for the U.S. child population, we draw on four nationally-representative longitudinal surveys with observations of children through the late-2000s, and use the National Health and Nutrition Examination Surveys as the standard of comparison. The model is first used to evaluate the ages at which Hispanic and black children???s higher obesity prevalence by early adolescence emerges most strongly. We find that Hispanic child obesity emerges earlier than black child obesity. Half of the 50 greater prevalence of obesity among Hispanic than non-Hispanic white children in 8th grade has emerged already by kindergarten. In contrast, less than a quarter of the 50 greater prevalence of obesity among black than white children in 8th grade emerges by kindergarten, and as much as half is generated between the 5th and 8th grades. To understand better the sources of obesity disparities emerging by kindergarten, we estimate two sets of multivariate regressions. Each set of regressions uses two nationally-representative surveys, with one survey in common across the two sets. The first set of regressions compares the obesity of black and white children and the second set compares the obesity of children of immigrant mothers (the majority of whom are Hispanic) with children of U.S.-born mothers. Mother???s pre-pregnancy weight status emerges as an important but not decisive factor in both sets of regressions across all three surveys. In particular, immigrant mothers??? overall lower obesity than that for U.S.-born mothers is not sufficient to prevent the children of immigrants from becoming more obese than the children of natives by kindergarten. The main innovations in statistical methods that we developed to generate these results are described, including the application of Markovian demographic models, pooled-survey model-fit diagnostics, and cross-survey multiple imputation for variables present in one survey but not the other. Finally, longitudinal survey data evaluation results are described. We focus on the problems of parental reporting of the height and weight components of the standard Body Mass Index (BMI) used in tracking the time series and socio-demographic group variations in U.S. child obesity. A simulation method is used to learn that parental under-reporting of their children???s rapidly changing height induces much larger biases in the estimation of obesity prevalence than does parental misreporting of their children???s weight.

    Michael Rendall is a Professor of Sociology and Associate Director of the Population Research Center at the University of Maryland, College Park and adjunct senior social scientist at the RAND Corporation. Between 2007 and 2011 Dr. Rendall served as Director of the RAND Population Research Center and Director of the Postdoctoral Program in Population Studies. His research has included analyses of fertility, family structure, and international and internal migration; the development of new statistical methods for combining survey and population data, and for the simulation of cohort and population dynamics. His current research is supported by R01HD061967 (PI: Rendall) in response to a 2008 request for applications jointly supported by OBSSR, NICHD, and NHLBI to propose ???Innovative Computational and Statistical Methodologies for the Design and Analysis of Multilevel Studies on Childhood Obesity.??? Professor Rendall has a Ph.D. in Sociology and A.M. in Economics from Brown University.

    Learning About U.S. Child Obesity from Multiple Longitudinal Surveys

  • The Developmental of Functional Circuits in the Retina
    • - Marla Feller, PhD, University of California, Berkeley (2012/06/21)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    The Feller lab is interested in the mechanisms that guide the assembly of neural circuits during development. They use the retina as a model system, where they have used a combination of conventional and two-photon imaging, electrophysiology and transgenic approaches to address two major questions. They study how immature retinal circuits generate retinal waves -- a term used to describe highly patterned spontaneous activity in the immature retina -- and what role this activity plays in the development of the visual system. Second, they study the development of the circuits that mediate direction selectivity in the retina. Current projects include: 1) Cellular mechanisms underlying retinal waves 2) Development of direction selectivity 3) Role of retinal waves in the maturation retinal projection to its primary targets in the CNS.

    For more information go to http://neuroseries.info.nih.gov

    The Developmental of Functional Circuits in the Retina

  • Advisory Committee to the Director (ACD) June 2012 Meeting (Day 1)
    • - National Institutes of Health, Office of the Director (2012/06/20)
    • - Category : Advisory Committee to the Director of the NIH
    Bi-annual meeting of the Advisory Committee to the Director. The Committee will provide advice on matters pertinent to National Institutes of Health (NIH) mission responsibilities in the conduct and support of biomedical research, medical science, and biomedical communications.

    For more information go to http://acd.od.nih.gov/

    Advisory Committee to the Director (ACD) June 2012 Meeting (Day 1)

  • Advisory Committee to the Director (ACD) June 2012 Meeting (Day 2)
    • - National Institutes of Health, Office of the Director (2012/06/20)
    • - Category : Advisory Committee to the Director of the NIH
    Bi-annual meeting of the Advisory Committee to the Director. The Committee will provide advice on matters pertinent to National Institutes of Health (NIH) mission responsibilities in the conduct and support of biomedical research, medical science, and biomedical communications.

    For more information go to http://acd.od.nih.gov/

    Advisory Committee to the Director (ACD) June 2012 Meeting (Day 2)