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  • Alzheimers Disease Research Summit 2012: Path to Treatment and Prevention (Day 2)
    • - NIA (2012/05/20)
    • - Category : Conferences
    The Summit convenes national and international experts in Alzheimers research. The key goal of the AD Research Summit 2012 is to formulate an integrated multidisciplinary research agenda that will accelerate the development of successful therapies for AD across the disease continuum. The Summit will also identify what types of resources/infrastructure and new public private partnerships are necessary to successfully implement this research agenda.

    For more information go to http://www.nia.nih.gov/newsroom/announcements/2012/02/save-date-alzheimers-research-summit-may-14-15-2012

    Alzheimers Disease Research Summit 2012: Path to Treatment and Prevention (Day 2)

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  • 2012 NIH Asian American Pacific Islander Heritage Observance (NIH Only)
    • - Kenneth M. Yamada, M.D., Ph.D., Chief, LABORATORY CELL & DEVELOPMENTAL BIOLOGY, NIDCR (2012/05/20)
    • - Category : Asian/Pacific Islander Observance (NIH Only)
    The 2012 NIH Asian American Pacific Islander Heritage Observance- Striving for Excellence in Leadership, Diversity and Inclusion sponsored by the Office of Equal Opportunity and Diversity Management.Keynote speaker is Dr. Kenneth M. Yamada, Chief, Laboratory of Cell and Developmental Biology, NIDCR.

    2012 NIH Asian American Pacific Islander Heritage Observance (NIH Only)

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  • The Evidence-to-Practice Gap: Teaching Clinicians Evidence-based Medicine
    • - W. Scott Richardson, M.D., GHSU/UGA Medical Partnership Campus (2012/05/20)
    • - Category : Special
    Medicine: Mind the Gap is a lecture series that explores issues at the intersection of research, evidence, and clinical practice？？？areas in which conventional wisdom may be contradicted by recent evidence. From the role of advocacy organizations in medical research and policy, to off-label drug use, to the effectiveness of continuing medical education, the seminar series will aim to engage the NIH community in thought-provoking discussions to challenge what we think we know and to think critically about our role in today？？？s research environment.

    Dr. Scott Richardson will discuss the various facets of evidence-based medicine ？？？ what it is, why we need it, and how to practice it. He will engage in a discussion on how clinicians can learn to practice evidence-based medicine even if they have already completed their formal training. He also will examine what it would take to incorporate evidence-based medicine into the newer curricula of medical schools, illustrating how his teaching institution is doing this.

    Dr. Richardson is an academic general internist at the GHSU/UGA Medical Partnership Campus, in Athens, Georgia, where he is Professor of Medicine and Campus Associate Dean for Curriculum. His principal scholarly interests are in clinical epidemiology, evidence-based health care and medical education. He is a co-author of the book Straus et al., Evidence-Based Medicine: How to Practice and Teach It, Fourth Edition (2011). Dr. Richardson is a member of the international Evidence-based Medicine Working Group, which authored the Users Guides to the Medical Literature series in the Journal of the American Medical Association, now published in book form. Dr. Richardson continues to work on the challenges of integrating evidence into clinical decisions, particularly in evidence-based clinical diagnosis. He is also working to incorporate evidence into the new curriculum at his institution and in medical education at all levels.

    This seminar is sponsored by the Office of Disease Prevention, National Institute on Alcohol Abuse and Alcoholism, and National Cancer Institute Division of Cancer Prevention.

    For more information, visit
    http://prevention.nih.gov/mindthegap/richardson.aspx

    The Evidence-to-Practice Gap: Teaching Clinicians Evidence-based Medicine

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  • Alzheimers Disease Research Summit 2012: Path to Treatment and Prevention (Day 1)
    • - National Institute on Aging (2012/05/19)
    • - Category : Conferences
    The Summit convenes national and international experts in Alzheimers research. The key goal of the AD Research Summit 2012 is to formulate an integrated multidisciplinary research agenda that will accelerate the development of successful therapies for AD across the disease continuum. The Summit will also identify what types of resources/infrastructure and new public private partnerships are necessary to successfully implement this research agenda.

    For more information go to http://www.nia.nih.gov/newsroom/announcements/2012/02/save-date-alzheimers-research-summit-may-14-15-2012

    Alzheimers Disease Research Summit 2012: Path to Treatment and Prevention (Day 1)

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  • Center for Scientific Review Advisory Council Meeting - May 2012 (NIH Only)
    • - Richard Nakamura, Larry Tabak, Sally Rockey, Della Hann, George Chacko (2012/05/19)
    • - Category : NIH Only
    Mandatory Bi-Annual meeting to review evaluate CSR Functions

    Center for Scientific Review Advisory Council Meeting - May 2012 (NIH Only)

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  • National Advisory Allergy and Infectious Diseases Council - May 2012 (NIH Only)
    • - Dr. Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases and Dr. John Mascola, Deputy Director, Vaccine Research Center, NIAID. (2012/05/19)
    • - Category : NIAID Council (NIH Only)
    The National Advisory Allergy and Infectious Diseases Council will meet in open session to hear presentations by the Institute Director and a guest speaker.

    National Advisory Allergy and Infectious Diseases Council - May 2012 (NIH Only)

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  • AIDS Research Advisory Committee - May 2012 (NIH Only)
    • - NIAID Division of AIDS (2012/05/19)
    • - Category : AIDS Research Advisory Committee (NIH Only)
    This is one of three annual AIDS Research Advisory Committee meetings.

    AIDS Research Advisory Committee - May 2012 (NIH Only)

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  • History of DNA Repair - Anecdotal Observations on the Origins of Mutation Research
    • - Dr Jan Drake, NIEHS, Research Triangle Park, NC (2012/05/19)
    • - Category : DNA Repair
    DNA Repair Interest Group videoconference

    For more information go to http://sigs.nih.gov/DNA-repair/Pages/default.aspx

    History of DNA Repair - Anecdotal Observations on the Origins of Mutation Research

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  • CC Grand Rounds: (1) Development of Therapeutic Interventions for Niemann-Pick Disease, Type C1 (2) From Metabolism to Immunity: The Story of Type 1 Glycogen Storage Disease
    • - (1) Forbes D. Porter, MD, PhD, Clinical Director and Acting Head, Program on Developmental Endocrinology and Genetics, NICHD (2) From Metabolism to Immunity: The Story of Type 1 Glycogen Storage Disease (2012/05/19)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: (1) Development of Therapeutic Interventions for Niemann-Pick Disease, Type C1 (2) From Metabolism to Immunity: The Story of Type 1 Glycogen Storage Disease

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: (1) Development of Therapeutic Interventions for Niemann-Pick Disease, Type C1 (2) From Metabolism to Immunity: The Story of Type 1 Glycogen Storage Disease

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  • Of Mice, Birds and Men: The Mouse Ultrasonic Song System has Features Once Throught Unique to Humans and Song Learning Birds
    • - Dr. Erich D. Jarvis, Duke University Medical Center Investigator, Howard Hughes Medical Institute (2012/05/19)
    • - Category : Wednesday Afternoon Lectures
    Humans and song-learning birds communicate acoustically using learned vocalizations. The characteristic features of this social communication behavior include vocal control by forebrain motor areas, a direct cortical projection to brainstem vocal motor neurons, and dependence on auditory feedback to develop and maintain learned vocalizations. These features have not been found in closely related primate and avian species that do not learn vocalizations. Male mice produce courtship ultrasonic vocalizations (USVs) with acoustic features similar to songs of song-learning birds. However, it is assumed that mice lack a forebrain system for vocal modification and that their USVs are innate. Dr. Jarvis will present his lab？？？s discovery of the mouse song system and show that it includes a localized motor cortex region, which？？？during singing？？？projects directly to brainstem vocal motor neurons and keeps songs more stereotyped and on pitch. His lab also discovered that male mice depend on auditory feedback to develop and maintain normal ultrasonic song. When cross-housed under competitive social conditions, substrains of mice that have differences in their songs can imitate each others？？？ pitch. Dr. Jarvis concludes that male mice have at least some neuroanatomical and behavioral features thought to be unique to humans and song-learning birds, suggesting that mice have limited vocal modification abilities or that a reevaluation of species differences is in order. His lab hypothesizes that the trait of vocal learning is not dichotomous, as long assumed, but a continuum with mice being intermediate between other well-studied species.

    The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    Of Mice, Birds and Men: The Mouse Ultrasonic Song System has Features Once Throught Unique to Humans and Song Learning Birds

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  • National Childrens Mental Health Awareness - The Developing Brain: What it means for treating adolescents
    • - National Institute of Mental Health (2012/05/18)
    • - Category : Conferences
    As part of National Children？？？s Mental Health Awareness, NIMH is sponsoring a videocast panel of children？？？s mental health researchers. Panelists will discuss neuroscience research findings related to: teen brain development, cognition and emotional and behavioral growth, and treatment for teens.

    National Childrens Mental Health Awareness - The Developing Brain: What it means for treating adolescents

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  • Genetic Disorders of Human Cerebral Cortical Development
    • - Christopher Walsh, MD, PhD, Harvard Medical School (2012/05/18)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    Christopher Walsh is Bullard Professor of Pediatrics and Neurology at Harvard Medical School, Chief of the Division of Genetics at Boston Childrens Hospital, and an Investigator of the Howard Hughes Medical Institute.

    Dr. Walsh completed his MD and PhD degrees at the University of Chicago. After a neurology residency and chief residency at Massachusetts General Hospital, he completed a fellowship in genetics at Harvard Medical School. He joined the faculty at Harvard Medical School in 1993, and has held the Bullard Professorship since 1999. He is formerly Director of the Harvard-MIT combined MD-PhD training program. Dr. Walsh？？？s research has focused on the development, evolution, and function of the cerebral cortex, the part of our brain responsible for our highest cognitive abilities. He has pioneered the analysis of human genetic diseases that disrupt the cerebral cortex, including autism, intellectual disability, seizures, and cerebral palsy, identifying genetic causes for more than a dozen brain diseases of children. His research entails worldwide collaborations with physicians and families, especially focusing on countries of the Persian Gulf region, where he has active collaborations in Qatar, Saudi Arabia, Jordan, Kuwait, and the United Arab Emirates.

    Among his awards are a Jacob Javits Neuroscience Investigator Award from the National Institute of Neurological Disorders and Stroke, the Dreifuss-Penry Award Epilepsy Research Award from the American Academy of Neurology, the Derek Denny-Brown Award and the Jacoby Award from the American Neurological Association, the Research Award from the American Epilepsy Society, and the Wilder Penfield Award from the Middle Eastern Medical Assembly. He is an elected member of the American Neurological Association, the American Association of Physicians, and an elected fellow of the American Association for the Advancement of Sciences.

    For more information go to http://neuroseries.info.nih.gov

    Genetic Disorders of Human Cerebral Cortical Development

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  • 2012 Joseph Leiter Lecture - Future Humanitarian Crises: Challenges to Practice, Policy & Public Health
    • - Dr. Frederick M. "Skip" Burkle, Harvard School of Public Health (2012/05/12)
    • - Category : Special
    The 2012 Joseph Leiter Lecture will be delivered by Dr. Frederick M. Burkle, at 2:00 p.m. on May 9, 2012, in National Library of Medicines Lister Hill Center Auditorium. The lectureship, which honors former NLM Associate Director for Library Operations, Joseph Leiter, Ph.D., is sponsored jointly by the National Library of Medicine and the Medical Library Association.

    Dr. Burkle is senior fellow and scientist, the Harvard Humanitarian Initiative, Harvard School of Public Health, and former senior scholar and now senior associate faculty and research scientist, the Center for Refugee & Disaster Response, Johns Hopkins University Medical Institutes. He also serves as a senior international public policy scholar, Woodrow Wilson Center for International Scholars, Washington, DC (2008-present).

    In addition, he serves as adjunct professor, and as a clinical professor of surgery and adjunct professor in tropical medicine, at the University of Hawaii. He is also adjunct professor, Department of Military & Emergency Medicine, Uniformed Services University of Health Sciences, Bethesda, MD, and the Department of Public Health and Tropical Medicine, John Cook University, Australia.

    2012 Joseph Leiter Lecture - Future Humanitarian Crises: Challenges to Practice, Policy & Public Health

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  • A few surprises in protein glycosylation
    • - Dr. Rado Goldman, Department of Oncology, Georgetown University (2012/05/12)
    • - Category : Proteomics
    Proteomics Interest Goup Lecture

    Glycosylation of proteins results in substantial micro-heterogeneity. This provides analytical challenges and opportunities for improved understanding of disease processes. Analysis of site specific protein glycoforms and genomic variants affecting protein glycosylation suggests novel ways to study the progression of liver disease to hepatocellular carcinoma.

    For more information, visit
    http://proteome.nih.gov

    A few surprises in protein glycosylation

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  • Your Eyes: Windows to Your Health
    • - Dr. Rachel Bishop (2012/05/11)
    • - Category : Focus on You Wellness
    Focus on You Wellness Lecture Series

    Did you know that your eyes are the only place in your body where blood vessels and nerve tissue can be seen directly? When your eye doctor dilates and examines them using special lenses, he or she can determine not only whether there are diseases present which might threaten vision or the health of your eye (such as cataracts, glaucoma, or macular degeneration); they can also identify changes which suggest body-wide disorders, such as high blood pressure, diabetes, and increased risk for stroke. This talk will illustrate some of these findings, and reveal why the eyes are rightly called the windows to your body？？？s health.

    Dr. Rachel Bishop is chief of the Consult Services Section in the Eye Clinic at the National Eye Institute, National Institutes of Health (NIH). She performs eye examinations on people who are participating in clinical trials throughout the many Institutes and Centers at the NIH. This involves monitoring medication and treatment effects, managing eye diseases, and performing surgeries.

    Your Eyes: Windows to Your Health

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  • CC Grand Rounds: Reframing Informed Consent: Understanding How Research Participants Make Decisions
    • - (1) Gwenyth R. Wallen, RN, PhD, Chief, Nursing Research and Translational Science, Nursing and Patient Care Services, CC (2) Christine Grady, MSN, PhD, Chief, Department of Bioethics, CC (3) Connie Ulrich, RN, PhD, Associate Professor, School of Nursing, and Department of Medical Ethics and Health Policy, School of Medicine, University of Pennsylvania (2012/05/11)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: Reframing Informed Consent: Understanding How Research Participants Make Decisions

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: Reframing Informed Consent: Understanding How Research Participants Make Decisions

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  • Self Stimulation？？？How Positive Feedback Loops Wire the Brain
    • - Bernardo L. Sabatini, M.D., Ph.D., Harvard Medical School Investigator, Howard Hughes Medical Institute (2012/05/11)
    • - Category : Wednesday Afternoon Lectures
    A great deal of brain development happens after birth. During this period, sensory inputs and patterns of activity within the brain drive the refinement of circuits and the formation of synapses. This is well established for parts of the brain that receive signals from the outside world, such as sensory systems. Much less is known about the function of activity in shaping the development of non-sensory and sub-cortical systems. Dr. Sabatini will show that activity in a recurrent loop between the basal ganglia and cortex acts in a self-reinforcing manner. Thus manipulations that promote the activity of the direct pathway through the basal ganglia, and hence activate cortex, lead to greater innervation of the basal ganglia. His lab proposes that such self-reinforcing systems ensure the correct wiring of sub-cortical systems that lack the stereotyped topographic organization of sensory systems. Lastly, his lab proposes that early perturbations of such mechanisms can contribute to developmental disorders such as cerebral palsy and attention deficit hyperactivity disorder.

    The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    For more information, visit:
    The NIH Directors Wednesday Afternoon Lecture Series

    Self Stimulation？？？How Positive Feedback Loops Wire the Brain

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  • HHSinnovates Round 5 (HHS Only)
    • - Kathleen Sebelius, HHS Secretary (2012/05/11)
    • - Category : HHS Only
    HHS Secretaries message to All HHS employees announcing the HHSinnovates Round 5

    HHSinnovates Round 5 (HHS Only)

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  • Using Mixed Methods to Optimize Dissemination and Implementation of Health Interventions
    • - NIH Office of Behavioral and Social Science Research (2012/05/10)
    • - Category : Conferences
    Mixed methods research is increasingly important for addressing complex problems facing public health. Mixed methods approaches are particularly well-suited to enhance our understanding of how to optimize dissemination and implementation (D&I) of evidence-based interventions. A challenge inherent in D&I research is that often neither a qualitative nor a quantitative approach alone is sufficient to fully understand the processes involved and/or outcomes resulting from the dissemination or implementation of a given intervention. Mixed methods research involves the intentional collection and integration of both qualitative and quantitative data and capitalizes on the strengths of each to enhance the breadth and depth of the researchers？？？ understanding of a problem. Mixed methods research is a tool that can help to ensure that evidence-base strategies to improve health and prevent disease are effectively delivered in clinical and public health practice.

    The goal of this workshop is to illustrate the utility of mixed methods approaches to improve and enhance dissemination and implementation research. Specifically, the workshop will:

    Provide a rationale for using mixed methods for dissemination and implementation research and identify the types of studies for which these methods are most appropriate Describe mixed methods research designs and examples of mixed methods studies in dissemination and implementation research Demonstrate effective integration of methods in grant writing and analytic plans Identify elements of a good mixed methods grant proposal by summarizing and expanding on the recently released report on Best Practices for Mixed Methods Research in the Health Sciences: http://obssr.od.nih.gov/scientific_areas/methodology/mixed_methods_research/index.aspx

    For more information go to http://conferences.thehillgroup.com/obssr/MixedMethodsDI/index.html

    Using Mixed Methods to Optimize Dissemination and Implementation of Health Interventions

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  • Lunchtime Dependent Care Seminar: Managing the Emotional Impact of Caregiving
    • - Kelly Collins, MA, LifeWork Strategies Inc. (2012/05/10)
    • - Category : Parenting
    There are many ups and downs when it comes to caring for a love one and experiencing feelings such as helplessness, guilt, anger, and depression. As you embrace both the joys and challenges of caregiving, it is essential to continually explore strategies to keep balance in your lives and find purpose in the demanding role of a caregiver. This seminar will explore the emotions associated with caregiving and discover ways to be resilient and healthy.

    Handout Slides

    For more information go to http://www.ors.od.nih.gov/pes/dats/childcare/Pages/index.aspx

    Lunchtime Dependent Care Seminar: Managing the Emotional Impact of Caregiving

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