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  • Demystifying Medicine - Hepatocellular Carcinoma: Mechanisms and Stem Cells (NIH Only)
    • - Snorri Thorgeirsson (NCI) and Itzhak Avitar (NCI) (2011/04/21)
    • - Category : Demystifying Medicine
    This event will include the presentation of patients, pathology, diagnosis and therapy context of major disease problems and current research. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. These seminar series are primarily directed toward PhD students, clinicians and program managers. All students, fellows and staff are welcome, as well.

    For more information, visit
    http://www1.od.nih.gov/oir/DemystifyingMed

    Demystifying Medicine - Hepatocellular Carcinoma: Mechanisms and Stem Cells (NIH Only)

  • NIH Pain Consortium Symposium
    • - NIH Pain Consortium (2011/04/21)
    • - Category : Conferences
    This annual symposium highlights advances in pain research supported by NIH. The theme for the 2011 meeting is: Co-Existing Pain and Non-pain Conditions.
    For more information, visit:
    http://guest.cvent.com/d/qdqb03

    NIH Pain Consortium Symposium

  • The Cardiac Organellar Protein Atlas (COPa) Library: Efforts to Advance Cardiovascular Biology and Medicine
    • - Peipei Ping, Ph.D., FAHA, UCLA (2011/04/20)
    • - Category : Proteomics
    NIH Proteomics Interest Group Seminar Series

    The rapid development of high accuracy and high sensitivity mass spectrometry technologies has revolutionized our understanding of proteins and their contribution to cellular function. However, there is an increasingly apparent disconnect between these state-of-the-art tools and their effective applications to advance cardiovascular biology and medicine. Despite progress made in certain areas of investigation, cardiovascular proteomic research faces three major challenges: the excessive cost of instrumentation; the limited accessibility of advanced proteomic technology to the cardiovascular community at large; and the overwhelming quantity and fragmented nature of mass spectra datasets lacking functional annotations. These economic, technological, and informatic limitations are prohibitive to further advancement of the field.

    To move the field forward, our investigator team identified several key challenges that commonly surround mass spectrometer data processing and non-targeted database searches. Accordingly, we constructed a Cardiac-specific Organelle Protein atlas (COPa) Library, which provides a specialized, comprehensive, and interactive resource for the cardiovascular community. We engineered a robust and high fidelity library to enable targeted protein and peptide data searches with detailed functional and phenotype annotations. This library will catalogue experimental peptide spectra, protein imaging data, and protein array data obtained from cardiovascular organelles of human as well as other species; it will contain a Wiki-like web interface to engage the participation of the cardiovascular community; and it will build a cardiovascular proteome knowledgebase with efforts from proteomic scientists, biologists, and cardiovascular clinicians.

    In summary, this COPa Library creates an essential tool box to support the translation of proteomic data into the advancement of cardiovascular biology and medicine; it will bridge the gap between traditional data-driven proteomic studies and hypothesis-driven investigations widely employed by the cardiovascular community, propelling innovation and new discoveries.

    For more information, visit
    http://proteome.nih.gov

    The Cardiac Organellar Protein Atlas (COPa) Library: Efforts to Advance Cardiovascular Biology and Medicine

  • Workshop on Long-term Preservation & Management of Electronic Health Records (Day 1)
    • - National Library of Medicine, Department of Veteran Affairs, National Archives and Records Administration, and National Institute of Standards and Technology (2011/04/17)
    • - Category : Conferences
    Electronic health-related patient information is vital for clinical care and medical research. However, systems interoperability for preservation, storage, and accessibility of such health data have not yet been defined.

    Clinical data in digital form represents a digital library, and inherits all the same administration and technical issues faced by digital libraries in other fields:
    • what to retain and for how long
    • how to handle obsolescence of hardware and software
    • interchange of information
    • costs
    • assignment of responsibility
    • standards
    In addition, clinical data involves issues of privacy, legal constraints, economics, and data ownership that complicate preservation even further. If preservation of clinical information is not addressed, valuable and irreplaceable information will become inaccessible, or disappear over time with disastrous consequences for patient care and research value.

    Replacing lost data even if possible, will entail huge costs for patients, clinicians, administrators, pharmacists, and potentially, the entire countrys economy.

    For more information, visit:
    http://ddpehr.nist.gov/home.php

    Workshop on Long-term Preservation & Management of Electronic Health Records (Day 1)

  • Social Context as Risk Regulator: Extending the Stream of Causation in Health Research
    • - Thomas A. Glass, Ph.D. (2011/04/16)
    • - Category : BSSR Lecture Series
    Causation is the central problem of health research. Our causal discourse shapes what we study, and how and where we intervene. The potential outcomes model is the most widely accepted causal framework in Epidemiology. However, many ???upstream??? factors of greatest interest to social scientists are incompatible with this framework. This contributes to a narrow focus on individual-level ???down-stream??? risk factors and to ineffective interventions that target individuals while ignoring social context.

    This lecture will review causal discourse in light of the stream of causation metaphor, and suggest the concept of a risk regulator to address several key challenges. We attempt to upgrade this metaphor with a three-dimensional socio-environmental topography of risk. We argue that public health research may be improved by focusing on health behaviors as strategic action in the context of opportunities and constraints imposed by particular social settings. Several examples are given to illustrate how existing analytic tools can be used to study risk regulators. Finally, attention is given to the need for more contextually embedded data and emerging methods of data analysis that may improve the study of the role of social context in health research.

    Social Context as Risk Regulator: Extending the Stream of Causation in Health Research

  • Should All Research Subjects Be Treated the Same?
    • - Baruch A. Brody, PhD, Leon Jaworski Professor of Biomedical Ethics and Director of the Center for Medical Ethics and Health Policy, Baylor College of Medicine, and Andrew Mellow Professor of Humanities, Department of Philosophy, Rice University; Case Presenter: Stephen A. Migueles, MD, Staff Clinician, HIV-Specific Immunity Section, Laboratory of Immunoregulation, NIAID (2011/04/16)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Ethics Rounds Lecture

    For more information, visit:
    http://www.cc.nih.gov/about/news/grcurrent.html

    Should All Research Subjects Be Treated the Same?

  • OFM Update and the FSR/FFR Reconciliation Calculator (HHS Only)
    • - Alan Whatley, Pamela Mayer and 11 Guest speakers (2011/04/16)
    • - Category : GMAC (HHS Only)
    This seminar will give attendees the opportunity to meet members of the OFM staff; find out what the Office of Financial Management (OFM) does and how OFM interacts with the Payment Management System (PMS) and Data Warehouse; attendees will learn how to interpret and process the new FFR.

    OFM staff will show how FSR/FFRs are reconciled (i.e., accepted / rejected / transferred from one institution to another / closed out). Attendees will get a better understanding on how to use the FSR/FFR Reconciliation Calculator.

    For more information, visit:
    http://odoerdb2-1.od.nih.gov/gmac/gmac/trs_main.html

    OFM Update and the FSR/FFR Reconciliation Calculator (HHS Only)

  • Lunch and Learn Parenting Seminars: Blended Families
    • - Risa J. Garon, LCSW-C, BCD, CFLE, LifeWork Strategies, Inc. (2011/04/16)
    • - Category : Parenting
    In a blended family, it is important that parents make the children and their relationships a priority as they integrate rules, rituals and traditions. Attend this seminar to discuss the critical role of respectful communication, quality time, healthy boundaries and special considerations. http://does.ors.od.nih.gov/childcare

    Acrobat Slides

    Lunch and Learn Parenting Seminars: Blended Families

  • Careers in Global Health: Fifth in the "How To" Series
    • - Lori Conlan, PhD (2011/04/16)
    • - Category : Career Development/OITE
    • Do you want to use your scientific skills, knowledge, and experience to improve the health and well-being of people around the world?

    • Are you interested in learning how idealism interacts with reality during the development of valuable and effective health programs?

    • Have you ever wondered what kinds of skills you would need for a transition into the global health field and how you would develop those skills?

    In this "How To" workshop, we will examine job sectors that employ global health professionals, the skills needed to get a job in the field, and how to prepare yourself for a career in global health. This is the fifth in the new OITE "How To" series. The series dissects a variety of career paths to explore what skills are necessary to succeed and how you can get those skills integrated into your resume as a grad students or postdoc.

    For more information, visit: http://www.training.nih.gov

    Careers in Global Health: Fifth in the "How To" Series

  • STEP Symposium - Humor and Healing: Laughing for Health and Well Being (HHS Only)
    • - Andy Jones (2011/04/15)
    • - Category : STEP (HHS Only)
    Everyone has heard: ???Laughter is the best medicine??? and now there is scientific evidence to support it. For example, mirthful laughter can improve blood flow, acting like ???internal jogging.??? This reduces stress, boosts human growth hormone and the immune system. In addition, cancer patients whose treatments include laughter therapy report reduced pain and more rapid return to regular activities at home. Come out of your office and laugh out loud with us. We???ll teach you the physiology of laughter and how it can work in medical treatment and every day life. You???ll experience your own laughter therapy and still call it ???work???! LOL

    Add to your calendar
    http://odoerdb2-1.od.nih.gov/oer/training/step/icalendar/step_calendar_humor_and_healing.ics

    For more information, visit
    http://odoerdb2-1.od.nih.gov/oer/training/step/step_training_20110405.htm

    STEP Symposium - Humor and Healing: Laughing for Health and Well Being (HHS Only)

  • Revised Peer Review Appeals Policy - a Train-the-Trainer event (HHS Only)
    • - Sally Rockey, Ann Hagan, Merrill Mitler, Sally Amero (2011/04/15)
    • - Category : ESA (HHS Only)
    The purpose of this train-the-trainer event is to inform NIH extramural staff of imminent revisions to the NIH policy concerning appeals of the initial peer review process. Members of EPMC, PLC, TAC, RPC, and GMAC are invited, along with all the IC Executive Officers and Appeals Officers. Additional staff may attend.

    The new appeals policy was developed at the request of the NIH Director to facilitate consistent handling of appeals across the agency. Before the revised appeals policy is issued publicly, members of the NIH functional committees (EPMC, PLC, TAC, RPC, GMAC), Executive Officers and Appeals Officers will have this opportunity to learn the new requirements and procedures for handling appeals, and to inform their IC colleagues of these changes.

    For more information, visit:
    http://odoerdb2.od.nih.gov/oer/training/esa/esa_training_20110412.htm

    Revised Peer Review Appeals Policy - a Train-the-Trainer event (HHS Only)

  • Drug Use in Racial/Ethnic Minority Populations: Avoiding Risks and Seeking Care
    • - Dr. Lula Beatty (2011/04/14)
    • - Category : Focus on You Wellness
    Focus on You Wellness Lecture Series

    Drug Use in Racial/Ethnic Minority Populations: Avoiding Risks and Seeking Care

  • Demystifying Medicine - Cardiovascular disease in the eras of imaging and stem cells (NIH Only)
    • - Bob Balaban (NHLBI) and Manfred Boehm (NHLBI) (2011/04/14)
    • - Category : Demystifying Medicine
    This event will include the presentation of patients, pathology, diagnosis and therapy context of major disease problems and current research. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. These seminar series are primarily directed toward PhD students, clinicians and program managers. All students, fellows and staff are welcome, as well.

    For more information, visit
    http://www1.od.nih.gov/oir/DemystifyingMed

    Demystifying Medicine - Cardiovascular disease in the eras of imaging and stem cells (NIH Only)

  • State of the Knowledge Workshop on ME/CFS Research (Day 1)
    • - ORWH (2011/04/14)
    • - Category : Conferences
    ORWH Workshop on ME/CFS

    State of the Knowledge Workshop on ME/CFS Research (Day 1)

  • State of the Knowledge Workshop on ME/CFS Research (Day 2)
    • - ORWH (2011/04/14)
    • - Category : Conferences
    ORWH Workshop on ME/CFS

    State of the Knowledge Workshop on ME/CFS Research (Day 2)

  • Reason for Hope - The Way Ahead (HHS Only)
    • - Dr. Jane Goodall (2011/04/14)
    • - Category : HHS Only
    The year 2010 marked a monumental milestone for the Jane Goodall Institute and its founder, Dr. Jane Goodall, DBE. Fifty years ago, Dr. Goodall, who is today a world-renowned primatologist, conservationist and UN Messenger of Peace, first set foot on the shores of Lake Tanganyika, in what is now Tanzania???s Gombe National Park. The chimpanzee behavioral research she pioneered there has produced a wealth of scientific discovery, and her vision has expanded into a global mission to empower people of all ages to make a difference for all living things.

    In her lecture, Dr. Goodall will reflect???both personally and professionally???on the meaning of the past five decades, the extraordinary changes the world has seen since 1960, and the impact these changes have had on people, animals and the environment we all share. In addition, she will discuss the role we must all play over the next 50 years to ensure a better future for generations to come.

    For more information about Dr. Goodall and her work, please visit:
    www.janegoodall.org

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Reason for Hope - The Way Ahead (HHS Only)

  • Neutrophil Extracellular Traps: From Infection to Autoimmunity
    • - Arturo Zychlinsky (2011/04/12)
    • - Category : Immunology
    Immunology Interest Group

    Neutrophil Extracellular Traps: From Infection to Autoimmunity

  • The Economic Burden of Health Inequalities in the United States
    • - Dr. Thomas LaVeist (2011/04/07)
    • - Category : Health Disparities
    NIH Health Disparities Seminar Series

    The presentation will focus on the financial burden health disparities are putting on America???s health care system and society at large

    The Economic Burden of Health Inequalities in the United States

  • Genetic Studies of Telencephalon Development
    • - John Rubenstein, M.D., Ph.D., University of California, San Francisco (2011/04/07)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    The goal of Dr. Rubenstein???s research is to elucidate fundamental mechanisms that regulate development of the forebrain and in parallel, whether disruption of these mechanisms underlie human disorders, such as autism, schizophrenia, mental retardation, epilepsy and craniofacial disorders. Investigations include studies on secreted factors, such as Fgf8 and Fgf17, that function in regionalization of the neural plate and cerebral cortex. They have shown that Fgf17 mutant mice have hypoplasia of their anterior cingulate gyrus, and behavioral deficits in social interactions. Ongoing studies also focus on defining transcription factors that control CNS development, including Nkx genes (specifying ventral neural progenitors) and Dlx1 and 2 (involved in differentiation of GABAergic neurons). In addition, Dr. Rubenstein has been involved in investigations on tangential migration in the CNS. Studying the migration of GABAergic neurons from the subcortical telencephalon into the cerebral cortex, both factors controlling movement of the cells as well as integration of the cells once they reach their destination. Finally, the lab has a longstanding clinical interest in Autism, with work focused on sequencing of candidate genes and functional analyses of mutant alleles.

    For more information, visit:
    http://neuroseries.info.nih.gov

    Genetic Studies of Telencephalon Development

  • Core Curriculum Part 5: Extramural R&D Contracting Policy and Procedure (HHS Only)
    • - Chuck Selden (2011/04/06)
    • - Category : Core Curriculum (HHS Only)
    This training will give the learner an insight into how the NIH uses contracts to support R&D efforts. It is intended as a supplement to the 40 hour R&D basic project officer course, or the 40 hour coursework for earning the FAC-COTR. It will feature readily usable advice for preparing an RFP, particularly the planning process, will cover specifics of contract review, and will give tips on post award contract administration, drawing on the experience of seasoned NIH employees. All within the bounds of the Federal Acquisition Regulations.

    For more information, visit
    http://esa.nih.gov/oer/training/esa/esa_cores_2011.htm

    Core Curriculum Part 5: Extramural R&D Contracting Policy and Procedure (HHS Only)