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- Childhood Growth: New Concepts, New Treatments
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- - Jeffrey Baron, MD, Chief, Section on Growth and Development, NICHD (2011/06/12)
- - Category : Clinical Center Grand Rounds
- Contemporary Clinical Medicine: Great Teachers: Eighth Annual John Decker Memorial Lecture
For more information, visit: http://www.cc.nih.gov/about/news/grcurrent.html
Childhood Growth: New Concepts, New Treatments
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- NICHD Advisory Council - June 2011
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- - NICHD (2011/06/11)
- - Category : National Advisory Child Health and Human Development Council
- To help achieve the goals of the Institute, the NACHHD Council is charged with advising, consulting with, and making recommendations to the NICHD director on matters relating to the research and research support activities and functions of the Institute.
NICHD Advisory Council - June 2011
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- The Health Data Initiative Forum 2011 (AM session)
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- - U.S. Department of Health and Human Services and the Institute of Medicine (2011/06/11)
- - Category : Conferences
- The U.S. Department of Health and Human Services and the Institute of Medicine will host The Health Data Initiative Forum on Thursday, June 9, 2011 to accelerate momentum for the public use of data and innovation to improve health.
The Forum, which builds on the success of The Community Health Data Initiative Forum: Harnessing the Power of Information to Improve Health, held in June 2010, will include a number of fast-paced demonstrations that present a range of tools and applications developed using health data, a series of discussion sessions, and a data and apps exposition where participants can interact with featured innovators, learn more about available data, and identify opportunities to expand upon current efforts.
The plenary sessions and the apps demonstration sessions will be webcast.
For more information, visit: http://www.iom.edu/healthdataforum
The Health Data Initiative Forum 2011 (AM session)
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- CC Grand Rounds:(1) New Imaging Approaches to Determining Morphology and Severity of Mitral Valve Disease (2) Surgical Approaches to Management of Mitral Valve Disease
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- - (1) Vandana Sachdev, MD, Staff Clinician and Director, Echocardiography Laboratory, NHLBI (2) Director, Cardiothoracic Surgery Research Program, NHLBI and Director, Cardiothoracic Surgery, NIH Heart Center at Suburban Hospital (2011/06/10)
- - Category : Clinical Center Grand Rounds
- CC Grand Rounds
For more information, visit: http://www.cc.nih.gov/about/news/grcurrent.html
CC Grand Rounds:(1) New Imaging Approaches to Determining Morphology and Severity of Mitral Valve Disease (2) Surgical Approaches to Management of Mitral Valve Disease
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- Integrin Function in T Cell Migration and Activation
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- - Yoji Shimizu, University of Minnesota Medical School (2011/06/10)
- - Category : Immunology
Integrin Function in T Cell Migration and Activation
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- Training on Human Subjects Protections: Part 3 (HHS Only)
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- - Ann Hardy and Maria Stagnitto (2011/06/10)
- - Category : ESA (HHS Only)
- WHO SHOULD ATTEND?
Scientific Review Officers, Program Officers, and Grants Management staff who are new to NIH, or new to human subjects research administration Other NIH extramural staff who want a refresher on human research protections
NOT SURE? CAN YOU CORRECTLY ANSWER THE FOLLOWING QUESTIONS- A study involves the use of specimens from cadavers plus identifiable clinical information retrieved from their medical records ？？？ is this human subjects research?
- Reviewers identify concerns with the proposed plan to recruit minorities in an application. Should this application also be coded as unacceptable for human subjects?
- NIH has determined that a particular study is not considered human subjects research. However, the PIs institutional IRB wants it to undergo review. Should NIH staff tell the Institution that IRB review is not necessary?
- What is the appropriate human subjects code for this grant?
Sessions II and III will be held on March 10, 2011 and June 2, 2011 in RK-2, rm 9112-9116 and will cover timely topics such as use of existing specimens. Details about these training sessions will be sent via email and posted on the web page listed below.
http://esa.nih.gov/oer/training/esa/esa_training_20101202.htm
Training on Human Subjects Protections: Part 3 (HHS Only)
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- Social Isolation and Health
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- - John T. Cacioppo, Ph.D., The University of Chicago (2011/06/10)
- - Category : Special
- The Matilda White Riley Lecture
Social species, by definition, form organizations that extend beyond the individual. These structures evolved hand in hand with behavioral, neural, hormonal, cellular, and genetic mechanisms to support them because the consequent social behaviors helped these organisms survive, reproduce, and care for offspring sufficiently long that they too reproduced, thereby ensuring their genetic legacy.
Social isolation represents a lens through which to investigate these behavioral, neural, hormonal, cellular, and genetic mechanisms. Evidence from human and nonhuman animal studies indicates that isolation heightens sensitivity to social threats (predator evasion) and motivates the renewal of social connections. The effects of perceived isolation in humans share much in common with the effects of experimental manipulations of isolation in nonhuman social species: increased tonic sympathetic tonus and HPA activation, and decreased inflammatory control, immunity, sleep salubrity, and expression of genes regulating glucocorticoid responses. Together, these effects contribute to higher rates of morbidity and mortality in older adults.
Social Isolation and Health
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- Stem cell approaches to understanding lung injury repair and lung cancer
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- - Carla F. Kim, PhD (2011/06/10)
- - Category : Stem Cell
- NCRM/SCIG Stem Cell Seminar Series: The broad interest of the Kim laboratory is to characterize the biology of stem cells in normal lung tissue and in lung disease. Carla Kim was the first person to develop a method to isolate a stem cell population from the adult murine lung, termed bronchioalveolar stem cells (BASCs), opening new avenues for understanding lung biology and disease.
They hypothesize that BASCs play an important role in lung injury repair and may be the targets in some forms of lung disease that involve injured or depleted bronchiolar and alveolar cells. Her lab is currently developing transgenic mouse strains and transplantation protocols to test the function of BASCs and other putative lung stem cells in vivo.
They are also engaged in comparative microarray gene expression studies to identify novel molecular markers for BASCs, bronchiolar and alveolar cells. Her lab has recently shown that epigenetic regulation, and specifically the Polycomb group proteins, regulates lung stem cell function. Her research has made important connections between stem cell biology and lung biology that both advance our basic understanding of lung cell complexity and elucidate concepts relevant for human health.
Stem cell approaches to understanding lung injury repair and lung cancer
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- Meeting the challenges in membrane protein structure determination: a tale of separating a pair of electrons in cyt bc1 complex
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- - Di Xia, Ph.D. (2011/06/09)
- - Category : NIH Directors Seminars
- Directors Seminar Series
Meeting the challenges in membrane protein structure determination: a tale of separating a pair of electrons in cyt bc1 complex
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- Confronting Obesity: Updates in Prevention and Treatment Research
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- - (1) Kong Y. Chen, PhD, MSCI, Director, Metabolic Research Core, Diabetes, Endocrinology, and Obesity Branch, NIDDK (2) Lawrence Appel, MD, Professor of Internal Medicine and Director, Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medicine (3) Tania Heller, MD, FAAP, Suburban Hospital Physician and Medical Director of Washington Center for Eating Disorders and Adolescent Obesity, and Clin Asst Professor, Georgetown University Hospital (2011/06/08)
- - Category : Medicine for the Public
- Medicine for Public
Confronting Obesity: Updates in Prevention and Treatment Research
For more information, visit: http://www.cc.nih.gov/about/news/mfp.shtml
Confronting Obesity: Updates in Prevention and Treatment Research
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- Mind the gap: A network of electrical synapses linking olfactory glomeruli in the Drosophila antennal lobe
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- - Rachel Wilson, Ph.D., Harvard Medical School (2011/06/08)
- - Category : Neuroscience
- Neuroscience Seminar Series
The goal of Dr. Wilson？？？s lab is to understand how sensory information is processed by neural circuits and to describe the mechanisms that underlie sensory processing. Specifically, her research is directed towards understanding olfactory processing in the fruit fly Drosophila melanogaster. Dr. Wilson has developed new tools for studying electrical activity in the fly brain which have enabled her apply electrophysiological techniques to gain detailed insight into how olfactory circuits are organized and how they process information efficiently. Dr. Wilson has received numerous honors and awards in recognition of her work, including the Eppendorf and Science Award (2007), a MacArthur Fellowship (2008), an HHMI Early Career Scientist Award (2009), and the Society for Neuroscience Young Investigator Award (2010). For more information, visit: http://neuroseries.info.nih.gov
Mind the gap: A network of electrical synapses linking olfactory glomeruli in the Drosophila antennal lobe
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- (1) Placenta Growth Factor and Endothelin in Sickle Cell Pulmonary Hypertension (2) Sickle Cell Disease,Vasculopathy,and Leg Ulceration
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- - (1) Gregory J. Kato, MD, Investigator and Head, Sickle Cell Vascular Disease Section, Cardiovascular and Pulmonary Branch, NHLBI (2) Caterina Minniti, MD, Staff Clinician and Director of Clinical Service for the Sickle Cell Unit, Cardiovascular and Pulmonary Branch, NHLBI (2011/06/03)
- - Category : Clinical Center Grand Rounds
- CC Grand Rounds
For more information, visit: http://www.cc.nih.gov/about/news/grcurrent.html
(1) Placenta Growth Factor and Endothelin in Sickle Cell Pulmonary Hypertension (2) Sickle Cell Disease,Vasculopathy,and Leg Ulceration
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- Actively Acquired Self-tolerance: How are Mirror Image Responses Signalled?
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- - Chris Goodnow (2011/06/03)
- - Category : Immunology
Actively Acquired Self-tolerance: How are Mirror Image Responses Signalled?
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- Big Epidemiology for Big Problems
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- - Dr. Jonathan Samet, University of Southern California (2011/06/02)
- - Category : Wednesday Afternoon Lectures
- Society？？？s expectations for the investment in biomedical research are simple but grand: to live a longer and healthier life. Realizing this goal involves research that generates evidence on genetic determinants of risk, on environmental factors that harm and benefit health, and on the interactions of genes and environmental factors. Evidence generated through epidemiological research will be pivotal in meeting this goal, but research approaches of the past will not be sufficient for the future.
Trends are already evident ？？？ larger studies and consortia for genome-wide association studies (GWAS) and efforts to more accurately capture exposures. The accompanying challenges are also becoming evident ？？？ the difficulties and costs of recruiting populations, new ethical problems, and anticipation of unforeseeable opportunities made possible by technological advances. This presentation looks to the future, anticipating the ？？？big problems？？？ that will be the focus of epidemiological researchers and how they will be addressed.
The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
For more information, visit: http://wals.od.nih.gov/
Big Epidemiology for Big Problems
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- IACC Subcommittee on Safety and Services Subcommittee Joint Meeting - May 2011
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- - Susan Daniels, Ph.D. (2011/06/02)
- - Category : Interagency Autism Coordinating Committee
- The Services and Safety Subcommittees of the IACC plan to meet jointly to discuss issues related to seclusion and restraint and autism spectrum disorder (ASD).
IACC Subcommittee on Safety and Services Subcommittee Joint Meeting - May 2011
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- National Advisory Allergy and Infectious Diseases Council-May 2011 (NIH Only)
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- - Dr. Anthony S. Fauci, Director, NIAID, and Dr. Daniel Rotrosen, Director, Division of Allergy, Immunology and Transplantation, NIAID (2011/06/02)
- - Category : NIAID Council (NIH Only)
- In open session the NAAIDC hears presentation by Dr. Anthony Fauci, Director, and other speakers.
National Advisory Allergy and Infectious Diseases Council-May 2011 (NIH Only)
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- AIDS Research Advisory Committee - May 2011 (NIH Only)
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- - NIAID (2011/06/02)
- - Category : AIDS Research Advisory Committee (NIH Only)
- AIDS Research Advisory Committee - May 2011
AIDS Research Advisory Committee - May 2011 (NIH Only)
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- Data Coordinating Centers？？？ Best Practices Working Group
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- - * NHLBI is the event sponsor. Drs. Kerry Lee and Sonja McKinlay will co-Chair this WG. (2011/06/02)
- - Category : Conferences
- The success of clinical trials depends on effective recruitment of subjects, safety of participants and accuracy of the data, activities that require Data Coordinating Centers (DCC) to integrate the efforts of individual Clinical Centers in large clinical trial programs. DCCs are responsible for many financial, administrative, human subjects protection, clinical site procurement and research activities. The goals of this Working Group are to identify and create a compendium of minimal standards, favorable characteristics and best practices for Data Coordinating Centers (DCC) that support Networks or multicenter clinical trials.
The compendium will be a resource for crafting application and review criteria and for evaluating DCCs as part of a large clinical trial program.
Data Coordinating Centers？？？ Best Practices Working Group
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- Preview of Crucial Conversations: Tools for Talking When Stakes are High
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- - Marianne Marlowe,Training Manager, Division of Extramural Activities Support (DEAS); Dr. Sheryl Brining, Director, Office of Review in the National Center for Research Resources (NCRR) (2011/06/02)
- - Category : GMAC (HHS Only)
- This lecture will focus on the following Tools for Talking When the Stakes are High:
- Resolve disagreements？？？accurately address concerns by talking respectfully, candidly, and skillfully with someone in a safe way.
- Build acceptance rather than resistance？？？give and receive feedback in a way that enhances relationships and improves results.
- Speak persuasively, not abrasively？？？effectively talk about high-stakes, emotional and controversial topics.
- Foster teamwork？？？get the right people involved in a way that ensures better decision-making and guarantees commitment and conviction.
For more information, visit http://odoerdb2.od.nih.gov/gmac/gmac/trs_main.html
Preview of Crucial Conversations: Tools for Talking When Stakes are High
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- Respect Thy Neighbor: Why We Will Not Cure Cancer by Treating Only the Cancer Cells
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- - Dr. Mina Bissell, Ph.D., Lawrence Berkeley National Laboratory (2011/06/02)
- - Category : Wednesday Afternoon Lectures
- Mina Bissell has been recognized for her lifetime contributions to the fields of breast cancer research, the enhanced role of extracellular matrix (ECM) and the nucleus environment to gene expression in normal and malignant tissues. These works have ushered and have changed some central paradigms that have strengthened the importance of context in the development of cancer.
The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Respect Thy Neighbor: Why We Will Not Cure Cancer by Treating Only the Cancer Cells