전체 8345
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- NIH VideoCast - National Advisory Eye Council (NAEC) - October 2016
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- - NEI, NIH (2016/11/24)
- - Category : Advisory Board Meetings and Workshops
- Paul A. Sieving, MD, PhD, the Director of the National Eye Institute (NEI), presides as Chair and Paul Sheehy, Ph.D., as Executive Secretary to the National Advisory Eye Council (NAEC). The meeting is open to the public from 08:30 a.m. until 12:35 p.m. then the meeting will be closed to the public for the review of confidentiality and conflict of interest procedures and a review of grant and cooperative agreement applications on visual disorders, preservation of sight, and the special health problems and requirements of individuals with visual impairments. It also conducts the second level peer review of grant applications.
For more information go to http://www.nei.nih.gov/about/naec/index.asp
NIH VideoCast - National Advisory Eye Council (NAEC) - October 2016
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- NIH VideoCast - A Celebration of 60 Years of Behavioral and Cognitive Neuroscience in the Laboratory of Neuropsychology (Day 1)
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- - Laboratory of Neuropsychology and Laboratory of Brain and Cognition, NIMH, NIH (2016/11/24)
- - Category : Conferences
- This one and a half day symposium will integrate significant scientific advances made over the last 60 years in the neurobiology of memory, perception, and action. Speakers will share insights from studies of nonhuman primates, humans, and rats, highlighting lesions, electrophysiology, imaging, and related techniques. Talks will focus on how these advances led to current scientific understanding, and how that trajectory points the way toward new research questions that will drive the field forward.
For more information go to http://nimh.nih.gov/ln2016
NIH VideoCast - A Celebration of 60 Years of Behavioral and Cognitive Neuroscience in the Laboratory of Neuropsychology (Day 1)
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- NIH VideoCast - Medicine: Mind the Gap Seminar: Guidelines for Screening Children
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- - David Grossman, M.D., M.P.H., Executive Medical Director, Senior Investigator, Pediatrician, Group Health Research Institute (2016/11/24)
- - Category : Medicine: Mind the Gap
- Medicine: Mind the Gap Seminar
Three-Part Series on Disease Prevention Screening
Topic #2 Guidelines for Screening Children:
Presented by David Grossman, M.D., M.P.H. Executive Medical Director, Senior Investigator, Pediatrician, Group Health Research Institute
Prevention is often viewed as the cornerstone of pediatrics and child health. This view is supported by the tremendous advances in the prevention of infectious diseases and even some non-chronic conditions, such as many types of injuries. Infectious disease prevention has resulted largely from advances in immunizations and the use of preventive medication. Injury deaths have largely been reduced by advances in environmental health and engineering, and not through clinical services. Despite these recognized advances, there are still significant gaps in our understanding of pediatric clinical preventive services, largely in the domains of screening asymptomatic children and providing behavioral interventions to improve healthful activities. The U.S. Preventive Services Task Force has identified a number of key evidence gaps in these areas and issued a call for research to close these gaps. This seminar will focus on the evidence gaps in children？？ clinical preventive services and will address how these gaps might be filled through a combination of different study designs that best address these gaps, including screening trials, treatment trials and observational evidence across a broad variety of conditions.
David C. Grossman, M.D., M.P.H., is Senior Investigator at the Group Health Research Institute, Executive Medical Director for Population and Purchaser Health Strategy, and a practicing pediatrician at the Group Health healthcare system in Seattle, WA. He is also Professor of Health Services and Adjunct Professor of Pediatrics at the University of Washington. In his current research and administrative roles, he leads Group Health leaders and researchers who address the design, promotion, delivery, and evaluation of population care services, including studies of the impact of health benefit design changes to promote prevention.
Medicine: Mind the Gap is a seminar series that explores research design, measurement, intervention, data analysis, and other methods of interest to prevention science. Dr. Grossman will accept questions about his presentation via email at prevention@mail.nih.gov and on Twitter with #NIHMtG.
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NIH VideoCast - Medicine: Mind the Gap Seminar: Guidelines for Screening Children
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- NIH VideoCast - A Celebration of 60 Years of Behavioral and Cognitive Neuroscience in the Laboratory of Neuropsychology (Day 2)
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- - Laboratory of Neuropsychology and Laboratory of Brain and Cognition, NIMH, NIH (2016/11/24)
- - Category : Conferences
- This one and a half day symposium will integrate significant scientific advances made over the last 60 years in the neurobiology of memory, perception, and action. Speakers will share insights from studies of nonhuman primates, humans, and rats, highlighting lesions, electrophysiology, imaging, and related techniques. Talks will focus on how these advances led to current scientific understanding, and how that trajectory points the way toward new research questions that will drive the field forward.
For more information go to http://nimh.nih.gov/ln2016
NIH VideoCast - A Celebration of 60 Years of Behavioral and Cognitive Neuroscience in the Laboratory of Neuropsychology (Day 2)
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- NIH VideoCast - Clinical Center Research Hospital Board - October 2016
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- - Office of the Director, NIH (2016/11/24)
- - Category : Advisory Board Meetings and Workshops
- The objective of the Board is to provide advice and recommendations to the NIH Director pertinent to maintaining excellence in hospital operations, safety and quality, regulatory compliance, clinical research, and hospital leadership performance oversight. The Board`s advice and recommendations may regard issues, processes, studies, and/or reports on a range of topics in relation to the NIH Clinical Center and the Chief Executive Officer`s (CEO) duties and authorities.
For more information go to https://ccrhb.od.nih.gov/charter.htm
NIH VideoCast - Clinical Center Research Hospital Board - October 2016
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- NIH VideoCast - Virtual Clinical Trials: Modernizing Comparative Studies
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- - Office of Cyber Infrastructure and Computational Biology, NIAID, NIH (2016/11/24)
- - Category : Conferences
- The NIAID Office of Cyber Infrastructure and Computational Biology (OCICB) is pleased to host our annual 2016 Bioinformatics & Computational Biosciences Festival, Virtual Clinical Trials: Modernizing Comparative Studies.
The clinical trials process is a key, but very costly, requirement for getting drugs and vaccines approved for use in the medical field. Virtual clinical trials (VCTs) replace one component of the trial with technology (i.e. digital patients, sites, investigators), and are a radical departure from the way traditional double-blinded placebo randomized controlled trials are conducted. While the traditional method is still considered the ？？old standard,？？proponents of the virtual method cite driving down the cost of drug development, improved patient engagement, and providing improved access as the benefits. Technology and online engagement is utilized to perform recruitment, patient counseling, remote monitoring, and data collection.
The festival will explore how virtual clinical trials are revolutionizing the typical randomized controlled study model. Creative thinkers from from government agencies, academia, and the private sector will be sharing innovative ideas and perspectives with the research community at the NIH, as our scientists look at ways to develop an ideal environment for clinical research and patient care.
For more information go to https://respond.niaid.nih.gov/conferences/bioinformatics2016
NIH VideoCast - Virtual Clinical Trials: Modernizing Comparative Studies
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- NIH VideoCast - Frederick National Laboratory Advisory Committee - October 2016
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- - NCI, NIH (2016/11/24)
- - Category : NCI Frederick Advisory Committee
- The 1st Virtual Meeting of the Frederick National Laboratory Advisory Committee
NIH VideoCast - Frederick National Laboratory Advisory Committee - October 2016
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- NIH VideoCast - Unraveling Vascular Inflammation: From Immunology to Imaging Symposium (Day 1)
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- - NHLBI, NIH (2016/11/24)
- - Category : Conferences
- Unraveling Vascular Inflammation: From Immunology to Imaging is the first symposium of its kind to focus on vascular inflammation emerging research as it relates to immunology, systemic inflammation and multi-modal imaging. The conference, which takes place October 24-25 at the National Institutes of Health？？ Natcher Conference Center, will bring together the world？？ most renowned experts in the field, providing a forum for international collaboration across disciplines to speed new discoveries, fill gaps in existing knowledge, and potentially lead to critical breakthroughs in ways to understand vascular inflammation as it relates to future cardiovascular disease events.
For more information go to https://www.nhlbi.nih.gov/news/events/unraveling-vascular-inflammation-immunology-imaging-2016
NIH VideoCast - Unraveling Vascular Inflammation: From Immunology to Imaging Symposium (Day 1)
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- NIH VideoCast - Dynamics of Synaptic Vesicle Trafficking at the Active Zone of Ribbon Synapses
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- - Gary G. Matthews, Ph.D., Professor, Department of Neurobiology & Behavior, Center for Molecular Medicine, Stony Brook University School of Medicine (2016/11/24)
- - Category : Neuroscience
- NIH Neuroscience Series Seminar
The research in Dr. Matthews？？laboratory is concerned with how neurons communicate. One focus of their work is the synaptic vesicle cycle, the process of exocytosis and endocytosis that mediates chemical neurotransmission. To study the regulation of synaptic exocytosis and endocytosis, they use electrophysiological assays, such as capacitance measurements, together with a variety of imaging techniques, including calcium imaging, confocal microscopy, evanescent field microscopy, and electron microscopy.
For more information go to https://neuroscience.nih.gov/neuroseries/Home.aspx
NIH VideoCast - Dynamics of Synaptic Vesicle Trafficking at the Active Zone of Ribbon Synapses
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- NIH VideoCast - TRACO 2016: Breast cancer and Cancer health disparities
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- - Farah Zia, MD, NCI, NIH and Brid M. Ryan, PhD, NCI, NIH (2016/11/24)
- - Category : TRACO
- Breast cancer and Cancer health disparities
For more information go to http://ccr.cancer.gov/trainee-resources-courses-workshops-traco
NIH VideoCast - TRACO 2016: Breast cancer and Cancer health disparities
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- NIH VideoCast - Secretary？？ Advisory Committee on Human Research Protections (Day 1)
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- - HHS (2016/11/24)
- - Category : Secretary`s Advisory Committees
- SACHRP provides expert advice and recommendations to the Secretary, through the Assistant Secretary for Health, on issues and topics pertaining to or associated with the protection of human research subjects. The committee is composed of 11 appointed voting members, with additional ex-officio members from Common Rule government agencies. SACHRP presently has two working subcommittees, the Subpart A Subcommittee (SAS) and the Subcommittee on Harmonization (SOH). The October 2016 meeting will include reports from both subcommittees. Topics include the following draft recommendations: Considerations for Single IRB Review, Benchmarking in Human Subjects Research, Regulatory Issues in Cluster Randomized Trials, Recommendations on OHRP and FDA draft guidance on IRB Written Procedures, and the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules, Appendix M. Time is allotted on both days for public comment.
NIH VideoCast - Secretary？？ Advisory Committee on Human Research Protections (Day 1)
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- NIH VideoCast - Unraveling Vascular Inflammation: From Immunology to Imaging Symposium (Day 2)
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- - NHLBI, NIH (2016/11/24)
- - Category : Conferences
- Unraveling Vascular Inflammation: From Immunology to Imaging is the first symposium of its kind to focus on vascular inflammation emerging research as it relates to immunology, systemic inflammation and multi-modal imaging. The conference, which takes place October 24-25 at the National Institutes of Health？？ Natcher Conference Center, will bring together the world？？ most renowned experts in the field, providing a forum for international collaboration across disciplines to speed new discoveries, fill gaps in existing knowledge, and potentially lead to critical breakthroughs in ways to understand vascular inflammation as it relates to future cardiovascular disease events.
For more information go to https://www.nhlbi.nih.gov/news/events/unraveling-vascular-inflammation-immunology-imaging-2016
NIH VideoCast - Unraveling Vascular Inflammation: From Immunology to Imaging Symposium (Day 2)
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- NIH VideoCast - Saving the Synapse: Develpmental Critical Periods and Amblyopia
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- - Carla J. Shatz, Ph.D., Professor, Department of Neurobiology, Stanford University School of Medicine (2016/11/24)
- - Category : Special
- NEI AGI Seminar Series in Neuroregeneration
NIH VideoCast - Saving the Synapse: Develpmental Critical Periods and Amblyopia
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- NIH VideoCast - Redox Biology 2016: Redox enzymes and Redox physiology
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- - Lisa Ridnour, Ph.D., NCI, NIH and Pal Pacher, M.D., Ph.D., NIAAA, NIH (2016/11/24)
- - Category : Redox Biology
- Redox enzymes and Redox physiology
For more information go to http://ccr.cancer.gov/trainee-resources-courses-workshops-rb
NIH VideoCast - Redox Biology 2016: Redox enzymes and Redox physiology
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- NIH VideoCast - Secretary？？ Advisory Committee on Human Research Protections (Day 2)
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- - HHS (2016/11/24)
- - Category : Secretary`s Advisory Committees
- SACHRP provides expert advice and recommendations to the Secretary, through the Assistant Secretary for Health, on issues and topics pertaining to or associated with the protection of human research subjects. The committee is composed of 11 appointed voting members, with additional ex-officio members from Common Rule government agencies. SACHRP presently has two working subcommittees, the Subpart A Subcommittee (SAS) and the Subcommittee on Harmonization (SOH). The October 2016 meeting will include reports from both subcommittees. Topics include the following draft recommendations: Considerations for Single IRB Review, Benchmarking in Human Subjects Research, Regulatory Issues in Cluster Randomized Trials, Recommendations on OHRP and FDA draft guidance on IRB Written Procedures, and the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules, Appendix M. Time is allotted on both days for public comment.
NIH VideoCast - Secretary？？ Advisory Committee on Human Research Protections (Day 2)
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- NIH VideoCast - Ethical and Regulatory Aspects of Clinical Research Session 4: Informed consent, research with adults with impaired decision making, and the ethics of research with big data
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- - Christine Grady, Scott Kim, Jeff Kahn (2016/11/24)
- - Category : Bioethics
- The Department of Bioethics offers this seven to eight week course annually each fall. The course is designed to provide an overview of the important issues in the ethics of human subject research for clinical investigators and others who participate in the conduct of research and is open to the entire NIH community as well as to those from outside NIH. Topics include the history of human subject research ethics, principles and guidelines, study design, subject recruitment, informed consent, and international research. The course is open to the entire NIH community as well as to those from outside NIH. The recommended textbook is Ethical and Regulatory Aspects of Clinical Research, edited by Emanuel et al (Johns Hopkins University Press). The course is taught by guest faculty and faculty members from the National Institutes of Health. This is a required academic program for Bioethics fellows.
NIH VideoCast - Ethical and Regulatory Aspects of Clinical Research Session 4: Informed consent, research with adults with impaired decision making, and the ethics of research with big data
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- NIH VideoCast - Interagency Autism Coordinating Committee - October 2016
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- - NIH (2016/11/24)
- - Category : Interagency Autism Coordinating Committee
- Meeting of the IACC
NIH VideoCast - Interagency Autism Coordinating Committee - October 2016
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- NIH VideoCast - All of Us Research Program Stakeholder Briefing
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- - Eric Dishman, NIH and Karriem Watson, University of Illinois (2016/11/24)
- - Category : Special
- Join Eric Dishman and Karriem Watson as they share exciting updates about the All of Us Research Program, formerly known as the Precision Medicine Initiative Cohort Program. Mr. Dishman is the Director of the All of Us Research Program and Mr. Watson is the engagement director for the University of Illinois Consortium, which is helping to building the All of Us program. Live questions can be submitted to PMI-CPOutreachTeam@mail.nih.gov
For more information go to https://www.nih.gov/precision-medicine-initiative-cohort-program
NIH VideoCast - All of Us Research Program Stakeholder Briefing
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- NIH VideoCast - Understanding Plasmodium-Specific Memory B Cells
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- - Marion Pepper, Ph.D., Assistant Professor, Department of Immunology, University of Washington (2016/11/24)
- - Category : Immunology
- Immunology Interest Group Seminar Series
Humoral immunity consists of pre-existing antibodies expressed by long-lived plasma cells and rapidly reactive memory B cells (MBC). Recent studies of MBC development and function after protein immunization have uncovered significant MBC heterogeneity. To clarify functional roles for distinct MBC subsets during malaria infection, we generated tetramers that identify Plasmodium-specific MBCs in both humans and mice. Long-lived murine Plasmodium-specific MBCs consisted of three populations: somatically hypermutated IgM+ and IgG+ MBC subsets and an unmutated IgD+ MBC population. Rechallenge experiments revealed that high affinity, somatically hypermutated Plasmodium-specific IgM+ MBCs proliferated and gave rise to antibody secreting cells that dominated the early secondary response to parasite rechallenge. IgM+ MBCs also gave rise to T cell-dependent IgM+ and IgG+B220+CD138+ plasmablasts or T cell-independent B220-CD138+ IgM+ plasma cells. Thus, even in competition with IgG+ MBCs, IgM+ MBCs are rapid, plastic, early responders to a secondary Plasmodium rechallenge and should be targeted by vaccine strategies.
Marion Pepper is an Assistant Professor in the Department of Immunology at the University of Washington. She received her PhD in Immunology from the University of Pennsylvania, working with Chris Hunter to study the antigen-specific CD4+ T cell response to Toxoplasma gondii. Dr. Pepper studied antigen-specific host responses to numerous pathogens during her post-doctoral training with Marc Jenkins at the University of Minnesota. Her lab focuses on CD4+ T and B cell responses to pathogens such as malaria and HIV, and in models of allergic asthma.
NIH VideoCast - Understanding Plasmodium-Specific Memory B Cells
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- NIH VideoCast - Pathways to NIH Leadership Positions Workshop
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- - Elena Juris, NIH, Derrick Prather, NIH, Pamela McClinton, NIH, Belinda Seto, NIH (2016/11/24)
- - Category : Career Development/OITE
- To increase the awareness of the NIH leadership training opportunities provided by the NIH Training Center to the NIH community and to encourage their participation for career development and advancement.
NIH VideoCast - Pathways to NIH Leadership Positions Workshop
