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  • NIH VideoCast - 2018 Physical Activity Guidelines Advisory Committee - Second Meeting (Day 1)
    • - The U.S. Department of Health and Human Services, Office of the Assistant Secretary for Health, Office of Disease Prevention and Health Promotion (2016/11/24)
    • - Category : Advisory Board Meetings and Workshops
    The 2018 Physical Activity Guidelines Advisory Committee will meet to deliberate science-based physical activity recommendations for the federal government to use in developing the 2018 Physical Activity Guidelines.

    NIH VideoCast - 2018 Physical Activity Guidelines Advisory Committee - Second Meeting (Day 1)

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  • NIH VideoCast - 2018 Physical Activity Guidelines Advisory Committee - Second Meeting (Day 2)
    • - The U.S. Department of Health and Human Services, Office of the Assistant Secretary for Health, Office of Disease Prevention and Health Promotion (2016/11/24)
    • - Category : Advisory Board Meetings and Workshops
    The 2018 Physical Activity Guidelines Advisory Committee will meet to deliberate science-based physical activity recommendations for the federal government to use in developing the 2018 Physical Activity Guidelines.

    NIH VideoCast - 2018 Physical Activity Guidelines Advisory Committee - Second Meeting (Day 2)

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  • NIH VideoCast - Controlling innate T cell development in the thymus by cytokine receptor signaling
    • - Hyun Park, PhD, Senior Investigator, Experimental Immunology Branch, CCR, NCI, NIH (2016/11/24)
    • - Category : NIH Director`s Seminars
    Director`s Seminar Series

    T cells are generated in the thymus and then exported into the periphery where they undergo further maturation and differentiation into effector T cells. Lineage choice into distinct effector T cell subsets is tightly controlled by cytokine signaling. Specifically, cytokines of the common g-chain (gc) family play critical roles in cell fate decision and acquisition of effector function. Conventionally, effector T cell generation has been viewed as a process limited to peripheral tissues. Recent reports, however, revealed that the thymus also produces effector T cells, and that these cells are phenotypically mature and functionally competent without having encountered antigens. Thymus-derived innate phenotype T cells include, among others, NKT cells, a subset of gd T cells and IFN-g producing innate CD8 T cells. Analogous to their peripheral counterparts, thymus-generated effector T cells also require cytokine signaling for lineage choice and effector function. Unlike peripheral effector T cells, however, the molecular basis for cytokine-driven lineage choice and effector molecule expression remains largely unknown. Here we address the role of gc cytokines in thymic NKT subset differentiation, and reveal a role for the IL-4 receptor/STAT6 axis in controlling cell fate decision of both NKT and innate CD8 T cells. Interrogating the mechanisms of innate effector T cell differentiation is important, as it provides further clues to understand the cellular basis of inflammation, autoimmunity, and other immunological diseases.

    NIH VideoCast - Controlling innate T cell development in the thymus by cytokine receptor signaling

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  • NIH VideoCast - Interagency Pain Research Coordinating Committee - October 2016
    • - NIH (2016/11/24)
    • - Category : Advisory Board Meetings and Workshops
    The Interagency Pain Research Coordinating Committee (IPRCC) is a Federal advisory committee created by the Department of Health and Human Services to enhance pain research efforts and promote collaboration across the government, with the ultimate goals of advancing the fundamental understanding of pain and improving pain-related treatment strategies.

    For more information go to https://iprcc.nih.gov

    NIH VideoCast - Interagency Pain Research Coordinating Committee - October 2016

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  • NIH VideoCast - Ludo Waltman Keynote: Bibliometrics & Research Assessment: A Symposium for Librarians and Information Professionals
    • - Ludo Waltman, Researcher, Centre for Science and Technology Studies of Leiden University, The Netherlands (2016/11/24)
    • - Category : Special
    Join us at the main National Institutes of Health (NIH) campus in Bethesda, Maryland for this free symposium and training. Librarians and information professionals from academic, corporate, and government institutions will share expertise, ideas and best practices in the production and delivery of research assessment services.

    For more information go to http://maryland.sla.org/bibliometrics-research-assessment-a-symposium-for-librarians-and-information-professionals

    NIH VideoCast - Ludo Waltman Keynote: Bibliometrics & Research Assessment: A Symposium for Librarians and Information Professionals

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  • NIH VideoCast - Katy B철rner Keynote: Bibliometrics & Research Assessment: A Symposium for Librarians and Information Professionals
    • - Katy B철rner, Distinguished Professor of Information Science, Indiana University, Bloomington (2016/11/24)
    • - Category : Special
    Join us at the main National Institutes of Health (NIH) campus in Bethesda, Maryland for this free symposium and training. Librarians and information professionals from academic, corporate, and government institutions will share expertise, ideas and best practices in the production and delivery of research assessment services.

    For more information go to http://maryland.sla.org/bibliometrics-research-assessment-a-symposium-for-librarians-and-information-professionals/

    NIH VideoCast - Katy B철rner Keynote: Bibliometrics & Research Assessment: A Symposium for Librarians and Information Professionals

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  • NIH VideoCast - Myelin, movement and motor skills learning
    • - William Richardson, Ph.D., Professor, Wolfson Institute for Biomedical Research, University College London (2016/11/24)
    • - Category : Neuroscience
    NIH Neuroscience Seminar Series

    Oligodendrocyte precursors (OPs or NG2 glia) are ~5% of all neural cells in the brain and spinal cord and they continue to generate myelin-forming oligodendrocytes throughout young adult life. Dr. Richardson？？ lab has shown recently that oligodendrocyte production is accelerated in adult mice within a few hours of their starting to practice a complex motor task, and that these newly-forming cells are required for learning. Dr. Richardson will present these data and discuss the role of new myelin in circuit selection and refinement during learning. He will also describe their unpublished work on AMPA receptor signaling in OPs and its role in controlling development of oligodendrocytes and myelin.

    For more information go to https://neuroscience.nih.gov/neuroseries/Home

    NIH VideoCast - Myelin, movement and motor skills learning

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  • NIH VideoCast - NCI Board of Scientific Advisors Virtual Meeting - October 2016
    • - NCI, NIH (2016/11/24)
    • - Category : NCI Board of Scientific Advisors
    The 2nd Virtual Meeting of the NCI Board of Scientific Advisors

    NIH VideoCast - NCI Board of Scientific Advisors Virtual Meeting - October 2016

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  • NIH VideoCast - NCL Lessons Learned Workshop 2016
    • - NCL Scientists, NCI, NIH (2016/11/24)
    • - Category : Conferences
    NCI`s Nanotechnology Characterization Lab (NCL) is providing an intensive workshop on the science of preclinical characterization of nanomaterials. This meeting will cover some of the "lessons learned" from the NCL`s testing of more than 350 nanotechnology-based candidate cancer treatments and diagnostics.

    The half-day session will cover methods for nanomaterial characterization, including strategies for evaluating batch-to-batch consistency, surface characterization, nanomaterial ADME/Tox and PK, sterility and endotoxin contamination, immunotoxicity, and linking physicochemical characterization to safety and efficacy. This session will highlight methods and case studies from the NCL`s three-phase Assay Cascade.

    For more information go to https://ncifrederick.cancer.gov/events/NCL2016/default.asp

    NIH VideoCast - NCL Lessons Learned Workshop 2016

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  • NIH VideoCast - TRACO 2016: Genomics and Case reports
    • - Jun S. Wei, Ph.D, NCI, NIH and Oluwadamilola Olaku, MD, NCI, NIH (2016/11/24)
    • - Category : TRACO
    Genomics and Case reports

    For more information go to http://ccr.cancer.gov/trainee-resources-courses-workshops-traco

    NIH VideoCast - TRACO 2016: Genomics and Case reports

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  • NIH VideoCast - Translational Stroke Research: Vision and Opportunities (Day 1)
    • - NINDS, NIH (2016/11/24)
    • - Category : Conferences
    Workshop Objectives:

    1) To review existing animal models and outcome measures and establish a vision on what is needed to move translational research forward in ischemic and hemorrhagic stroke.

    2) To evaluate potential infrastructures and approaches for preclinical studies with a rigorous experimental design with similar standards applied in human clinical trials.

    3) Perspectives from StrokeNet regarding opportunities in reverse-translation, and harmonization of data-sharing, toolbox, and Common Data Elements.

    For more information go to http://www.etouches.com/nindstranslationalstrokeresearch2016

    NIH VideoCast - Translational Stroke Research: Vision and Opportunities (Day 1)

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  • NIH VideoCast - Strategies for an HIV Cure 2016 (Day 1)
    • - National Institute of Allergy and Infectious Diseases, NIH (2016/11/24)
    • - Category : Conferences
    This scientific meeting is focused on innovative and collaborative research strategies to cure HIV infection. Investigators from NIH-funded Martin Delaney Collaboratories and other programs related to HIV persistence and cure, investigators in complementary disciplines, and community members will share scientific results and engage in active discussion about the merits of various approaches under investigation. These discussions are intended to stimulate new collaborations and ideas for future research. The meeting is sponsored by the Division of AIDS at the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), and will cover a comprehensive range of topics spanning basic and translational research, drug discovery and development, and clinical research.

    For more information go to https://respond.niaid.nih.gov/conferences/hivcuremeeting2016

    NIH VideoCast - Strategies for an HIV Cure 2016 (Day 1)

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  • NIH VideoCast - TRACO 2016: Functional genomics and HSP90 inhibitors
    • - Natasha J. Caplen, Ph.D., NCI, NIH and Leonard M. Neckers, Ph.D., NCI, NIH (2016/11/24)
    • - Category : TRACO
    Functional genomics and HSP90 inhibitors

    For more information go to http://ccr.cancer.gov/trainee-resources-courses-workshops-traco

    NIH VideoCast - TRACO 2016: Functional genomics and HSP90 inhibitors

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  • NIH VideoCast - Strategies for an HIV Cure 2016 (Day 2)
    • - National Institute of Allergy and Infectious Diseases, NIH (2016/11/24)
    • - Category : Conferences
    This scientific meeting is focused on innovative and collaborative research strategies to cure HIV infection. Investigators from NIH-funded Martin Delaney Collaboratories and other programs related to HIV persistence and cure, investigators in complementary disciplines, and community members will share scientific results and engage in active discussion about the merits of various approaches under investigation. These discussions are intended to stimulate new collaborations and ideas for future research. The meeting is sponsored by the Division of AIDS at the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), and will cover a comprehensive range of topics spanning basic and translational research, drug discovery and development, and clinical research.

    For more information go to https://respond.niaid.nih.gov/conferences/hivcuremeeting2016

    NIH VideoCast - Strategies for an HIV Cure 2016 (Day 2)

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  • NIH VideoCast - Regulation of Dual Incision and Repair Synthesis in Human Nucleotide Excision Repair
    • - Dr Orlando Scharer, SUNY Stony Brook, NY (2016/11/24)
    • - Category : DNA Repair
    DNA repair videoconference

    Acrobat Slides

    NIH VideoCast - Regulation of Dual Incision and Repair Synthesis in Human Nucleotide Excision Repair

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  • NIH VideoCast - ContentMine: High-Throughput Extractions of Facts from Scientific Articles
    • - Peter Murray-Rust, D.Phil, University of Cambridge and Founder of the ContentMine Project (2016/11/24)
    • - Category : Special
    The NIH Frontiers in Data Science Lecture Series

    "ContentMine: High-Throughput Extractions of Facts from Scientific Articles"

    Dr. Peter Murray-Rust, University of Cambridge and Founder of the ContenMine Project

    There are millions of scientific articles published each year, but much of the content is not accessible because it is non-machine-readable or hidden in supplemental information or bitmapped figures. Content Mining (Text-and-Data Mining/TDM) turns this semi-structured material into semantic form (XML) and annotates it with known metadata. EuropePMC, which works closely with PubMedCentral, provides an API for rapid fulltext search and retrieval of fulltext. ContentMine software then extracts "facts" with a number of "facet" tools: word search, regexes, bespoke text tools, chemical NLP (OSCAR), and certain diagram types (phylogenetic trees). The "facts" can be mapped onto triples and incorporated into Wikidata or used to annotate the text to help human readers. Common facets are often supported by dictionaries, but they can be easily extended by anyone with a list of words. Using heuristics, data can be extracted from common diagram types. The vision is to develop a communal open toolbox that can be extended and validated for a wide range of purposes. However, many rightsholders are trying to control TDM through technical and legal means. There is a recent legal exception in the U.K. that allows for text mining of facts for scientific research. The University of Cambridge is doing this and publishing to the open web. This talk will have live demos, many accessible to the participants during the talk. ABOUT THE SPEAKER: Dr. Peter Murray-Rust is Founder of the ContentMine project which has used machines to liberate more than 100,000,000 facts from scientific literature. His research interests involve the automated analysis of data in scientific publications and the creation of virtual scientific communities. He has applied this to Chemistry through the development of the Chemical Markup Language (ChemML or CML). Dr. Murray-Rust holds a Doctor of Philosophy from the University of Oxford. His academic career spans more than thirty years in Computational Chemistry and Molecular Informatics at the Glaxo Group Research at Greenford, University of Nottingham, and University of Cambridge. He is known internationally for his activism in scientific open access and open data, which has been primarily focused on making scientific knowledge from literature freely available.

    For more information go to https://datascience.nih.gov/community/datascience-at-nih/frontiers

    NIH VideoCast - ContentMine: High-Throughput Extractions of Facts from Scientific Articles

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  • NIH VideoCast - Ethical and Regulatory Aspects of Clinical Research Session 7: Ethics of Pragmatic Trials and Incidental Findings
    • - Scott Kim, CC, NIH and Ben Berkman, CC, NIH and NHGRI, NIH (2016/11/24)
    • - Category : Bioethics
    The Department of Bioethics offers this seven to eight week course annually each fall. The course is designed to provide an overview of the important issues in the ethics of human subject research for clinical investigators and others who participate in the conduct of research and is open to the entire NIH community as well as to those from outside NIH. Topics include the history of human subject research ethics, principles and guidelines, study design, subject recruitment, informed consent, and international research. The course is open to the entire NIH community as well as to those from outside NIH. The recommended textbook is Ethical and Regulatory Aspects of Clinical Research, edited by Emanuel et al (Johns Hopkins University Press). The course is taught by guest faculty and faculty members from the National Institutes of Health. This is a required academic program for Bioethics fellows.

    NIH VideoCast - Ethical and Regulatory Aspects of Clinical Research Session 7: Ethics of Pragmatic Trials and Incidental Findings

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  • NIH VideoCast - Strategies for an HIV Cure 2016 (Day 3)
    • - National Institute of Allergy and Infectious Diseases, NIH (2016/11/24)
    • - Category : Conferences
    This scientific meeting is focused on innovative and collaborative research strategies to cure HIV infection. Investigators from NIH-funded Martin Delaney Collaboratories and other programs related to HIV persistence and cure, investigators in complementary disciplines, and community members will share scientific results and engage in active discussion about the merits of various approaches under investigation. These discussions are intended to stimulate new collaborations and ideas for future research. The meeting is sponsored by the Division of AIDS at the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), and will cover a comprehensive range of topics spanning basic and translational research, drug discovery and development, and clinical research.

    For more information go to https://respond.niaid.nih.gov/conferences/hivcuremeeting2016

    NIH VideoCast - Strategies for an HIV Cure 2016 (Day 3)

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  • NIH VideoCast - Barmes Global Health Lecture - Against Balkanization: Research + Training + Care = Global Health Equity
    • - Paul Farmer, MD, PhD, Partners In Health (2016/11/24)
    • - Category : David E. Barmes - Global Health
    Paul Farmer, MD, PhD, who is a founding director and chief strategist of the international nonprofit organization Partners In Health, will deliver the 2016 David E. Barmes Global Health Lecture on the NIH campus in Bethesda, Md. The title of his talk is "Against Balkanization: Research + Training + Care = Global Health Equity？？" The event is co-sponsored by NIH`s National Institute of Dental and Craniofacial Research (NIDCR) and the Fogarty Intern？？tional Center.

    Dr. Farmer is well known for dedicating his life to improving the health of the world？？ poorest people. As a medical anthropologist and physician who co-directs Partners In Health, he provides health care services, conducts research, and advocates on behalf of those who are sick and living in poverty. Over the past 28 years, Partners In Health has expanded operations from the original site in Haiti to 10 other countries around the world. Dr. Farmer and his colleagues have pioneered novel community-based strategies to deliver high-quality health care in low-resource settings.

    The David E. Barmes Global Health Lecture series honors the late David Edward Barmes, special expert for international health at the National Institute of Dental and Craniofacial Research (NIDCR).

    For more information go to http://www.nidcr.nih.gov/NewsAndFeatures/Announcements/2016-David-E--Barmes-Global-Health-Lecture.htm

    NIH VideoCast - Barmes Global Health Lecture - Against Balkanization: Research + Training + Care = Global Health Equity

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  • NIH VideoCast - CC Grand Rounds: 1) Glycosylation and Immunology: Friends and Foes and 2) Sugar Metabolism and Allergic Disease
    • - 1) Sergio Rosenzweig, MD, PhD, Chief, Immunology Service, Department of Laboratory Medicine, CC, NIH and 2) Jonathan Lyons, MD, Assistant Clinical Investigator, Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, NIAID, NIH (2016/11/24)
    • - Category : Clinical Center Grand Rounds
    CC Grand Rounds: 1) Glycosylation and Immunology: Friends and Foes and 2) Sugar Metabolism and Allergic Disease

    For more information go to http://www.cc.nih.gov/about/news/grcurrent.html

    NIH VideoCast - CC Grand Rounds: 1) Glycosylation and Immunology: Friends and Foes and 2) Sugar Metabolism and Allergic Disease

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