전체 8345
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- Dan Ihde Memorial Lecture: From Genes to Treatment (NIH-Only)
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- - Giuseppe Giaccone, M.D., Ph.D. (2010/11/18)
- - Category : NCI CCR Grand Rounds (NIH Only)
- Dr. Giaccone received his M.D., cum laude from the University of Torino Medical School in 1980, followed by training in clinical oncology and internal medicine at the University of Torino. He spent the next 2 years working in the National Cancer Institutes Medical Oncology Branch under the direction of Dr. John Minna. Following his training at NCI, Dr. Giaccone received his Ph.D., from the Free University Medical Center in Amsterdam, The Netherlands. He then served as a senior medical oncologist at the Free University Medical Center from 1990 to 2000, when he was appointed professor of medical oncology. Dr. Giaccone became head of the medical centers Department of Medical Oncology in 2003. In 2007, he joined NCI？？？s Center for Cancer Research as chief of the Medical Oncology Branch. Dr. Giaccone has published more than 400 peer-reviewed papers and contributed to more than 30 book chapters. He is an internationally recognized expert in the field of lung cancer and developmental therapeutics and has played a major role in the European Organization for Research and Treatment of Cancer (EORTC), serving as a member of the EORTCs Lung Cancer Cooperative Group since 1982 and as its chair from 1993 to 2000. His current research interests are the study of the biology of thoracic malignancies and drug development.
NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link: http://bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx
Dan Ihde Memorial Lecture: From Genes to Treatment (NIH-Only)
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- Introduction to Grant Writing I: Demystifying the NIH Grant Review Process
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- - Dr. Marita Hopmann, NICHD (2010/11/18)
- - Category : Career Development/OITE
- Most Scientists who write grants agree that the planning, writing, and submission (and resubmission) process can be challenging. However, all agree that the more you understand about the process, the easier it is. Join us for this first session of a two-part introductory series on NIH grants. This workshop focuses on finding funding opportunities at the NIH and beyond and elucidating aspects of the NIH grant review process, such as understanding the NIH peer review system; demystifying study sections; and the new NIH submission guidelines and review criteria.
http://www.training.nih.gov
Introduction to Grant Writing I: Demystifying the NIH Grant Review Process
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- Sham Neurosurgical Procedures in Clinical Trials for Neurodegenerative Diseases: Scientific and Ethical Considerations (Day 1)
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- - OBA, OD and NINDS, NIH (2010/11/18)
- - Category : Conferences
- The randomized, placebo-controlled clinical trial is generally viewed as the gold-standard in clinical investigation. However, when a trial involves a sham surgical procedure, unique scientific and ethical issues emerge. There are several examples of positive findings in open label studies of cell or gene therapies in Parkinson？？？s disease where subsequent trials which included a sham neurosurgical arm failed to show a difference between treatment arms. While sham neurosurgical arms have often been included in recent gene therapy trials for Parkinson？？？s disease (four of six that have been initiated since 2003) and Alzheimer？？？s disease (one trial started enrolling in November of 2008), their use is not without controversy.
As novel therapies are developed for neurodegenerative diseases, questions will arise about whether to include a sham arm and, if so, at what stage in development. Institutional Review Boards and patients will face complex decisions regarding such studies.
The NIH Office of Biotechnology Activities, Office of the Director and the National Institute of Neurological Disorders and Stroke have developed this conference to explore the scientific and ethical issues regarding sham neurosurgical arms and to provide a foundation for the development of points to consider when designing clinical trials which involve delivery to the central nervous system. The specific goals are to:
？？？ Increase our understanding of the utility and limitations of sham neurosurgical procedures through a review of the prior clinical trial experience in Parkinson？？？s disease
？？？ Address how experiences from trials in Parkinson？？？s disease may inform clinical trial design for other neurodegenerative disorders including Alzheimer？？？s disease, amyotrophic lateral sclerosis (ALS) and Huntington？？？s disease
？？？ Discuss the scientific and ethical issues raised by the use of sham neurosurgical procedures, including trial design, subject recruitment, risk assessment, and informed consent
？？？ Explore the perspective of patients regarding the design of trials that may involve sham neurosurgical procedures
Sham Neurosurgical Procedures in Clinical Trials for Neurodegenerative Diseases: Scientific and Ethical Considerations (Day 1)
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- CC Grand Rounds: (1) Updates in Hepatology (2) Familial Midgut Carcinoid Tumor
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- - Theo Heller, MD and Stephen Wank, MD (2010/11/18)
- - Category : Clinical Center Grand Rounds
- Theo Heller, MD,
Staff Clinician, Liver Diseases Branch, NIDDK
Stephen Wank, MD,
Chief, Digestive Diseases Branch, NIDDK
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
CC Grand Rounds: (1) Updates in Hepatology (2) Familial Midgut Carcinoid Tumor
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- NIH Noons In June - 2010
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- - Pat Baillie (2010/11/18)
- - Category : Diversity (NIH Only)
- NIH Lesbian, Gay, Bisexual and Transgender (LGBT) Pride Month Observance
NIH Noons In June - 2010
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- PSC All Hands Meeting - June 2010 (HHS-Only)
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- - Paul Bartley (2010/11/18)
- - Category : PSC Programs (HHS Only)
- Program Support Center All Hands Meeting
PSC All Hands Meeting - June 2010 (HHS-Only)
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- Regulating the Activity of MicroRNAs in Vertebrate Cells (NIH Only)
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- - Dr. Joan Steitz, Yale University (2010/11/18)
- - Category : NIH Only
- Joan Steitz, PhD, will present a Wednesday Afternoon Lecture on June 30, 2010. As the Sterling Professor of Molecular Biophysics and Biochemistry at Yale University and an investigator for the Howard Hughes Medical Institute, Dr. Steitz will present Regulating the Activity of MicroRNAs in Vertebrate Cells.
RNA-protein complexes (RNPs) are important for every step of gene expression. Dr. Steitz？？？s lab concentrates on RNPs of the nucleus, where the most famous small nuclear RNPs (snRNPs) participate in pre-mRNA splicing. Current efforts are aimed at understanding how the exon junction complex (EJC) is deposited after splicing and how its components relate to other nuclear events, how splicing is linked to 3-end formation of histone mRNAs, which lack polyA tails, employs many of the same factors that are needed for the cleavage and polyadenylation of most mRNAs.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Regulating the Activity of MicroRNAs in Vertebrate Cells (NIH Only)
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- Plasmacytoid Dendritic Cells Sense Nucleic Acid in Viral Infection and Autoimmune Disease
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- - Dr. Yang-Jun Liu (2010/11/18)
- - Category : Immunology
- Yong-Jun Liu is one of the best immunologists in the world. He has made significant contributions to several fields of immunology, especially human immunology. In his early work, he identified BCR and CD40 signaling as one of the major molecular mechanisms for selecting high affinity antigen specific B cells in germinal centers, an important mechanism for affinity maturation in antibody responses. He characterized human B cell subsets and identified molecular regulation of germinal center B cell differentiation. Yong-Jun is the one who discovered a new cell type in the immune system: plasmacytoid dendritic cells, which opened a new arena for dendritic cell immunology. Recently, he discovered a critical role for TSLP in DC-mediated allergic inflammation and T cell development. He has also shown that Hassalls corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in the human thymus.
Yong-Jun has published more than 200 papers which have been cited over 24,000 times. He has received many awards and honors for his outstanding work in immunology, including in 2006 The Dana Foundation Award for human Immunology Research and in 2007 The AAI Presidential Symposium Lecture. Yong-Jun is an engaging speaker who keeps his audience awake and on their toes and will undoubtedly deliver a seminar that you will not want to miss.
The Immunology Interest Group
Plasmacytoid Dendritic Cells Sense Nucleic Acid in Viral Infection and Autoimmune Disease
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- Sham Neurosurgical Procedures in Clinical Trials for Neurodegenerative Diseases: Scientific and Ethical Considerations (Day 2)
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- - OBA, OD and NINDS, NIH (2010/11/18)
- - Category : Conferences
- The randomized, placebo-controlled clinical trial is generally viewed as the gold-standard in clinical investigation. However, when a trial involves a sham surgical procedure, unique scientific and ethical issues emerge. There are several examples of positive findings in open label studies of cell or gene therapies in Parkinson？？？s disease where subsequent trials which included a sham neurosurgical arm failed to show a difference between treatment arms. While sham neurosurgical arms have often been included in recent gene therapy trials for Parkinson？？？s disease (four of six that have been initiated since 2003) and Alzheimer？？？s disease (one trial started enrolling in November of 2008), their use is not without controversy.
As novel therapies are developed for neurodegenerative diseases, questions will arise about whether to include a sham arm and, if so, at what stage in development. Institutional Review Boards and patients will face complex decisions regarding such studies.
The NIH Office of Biotechnology Activities, Office of the Director and the National Institute of Neurological Disorders and Stroke have developed this conference to explore the scientific and ethical issues regarding sham neurosurgical arms and to provide a foundation for the development of points to consider when designing clinical trials which involve delivery to the central nervous system. The specific goals are to:
？？？ Increase our understanding of the utility and limitations of sham neurosurgical procedures through a review of the prior clinical trial experience in Parkinson？？？s disease
？？？ Address how experiences from trials in Parkinson？？？s disease may inform clinical trial design for other neurodegenerative disorders including Alzheimer？？？s disease, amyotrophic lateral sclerosis (ALS) and Huntington？？？s disease
？？？ Discuss the scientific and ethical issues raised by the use of sham neurosurgical procedures, including trial design, subject recruitment, risk assessment, and informed consent
？？？ Explore the perspective of patients regarding the design of trials that may involve sham neurosurgical procedures
Sham Neurosurgical Procedures in Clinical Trials for Neurodegenerative Diseases: Scientific and Ethical Considerations (Day 2)
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- Choreographing the Tango between Hepatitis C Virus and Cells by Functional Genomic Approach (NIH Only)
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- - T. Jake Liang, M.D. (2010/11/18)
- - Category : NCI CCR Grand Rounds (NIH Only)
- Dr. Liang graduated magna cum laude from Harvard College and received his M.D., magna cum laude from Harvard Medical School. He completed his internal medicine residency training at New York University/Bellevue Hospital Center and fellowship training in gastroenterology and hepatology at Massachusetts General Hospital. He served as a faculty member and assistant professor of medicine at Massachusetts General Hospital and Harvard Medical School. In 1996, he was recruited to the intramural program of the National Institutes of Health？？？s (NIH) National Institute of Diabetes and Digestive and Kidney Diseases as chief of the Liver Diseases Section and was later promoted to chief of the Liver Diseases Branch. While at NIH, Dr. Liang established a fully integrated program of clinical investigation and basic research in liver disease. He is the training director of the NIH hepatology fellowship program, which has trained and produced many international academic leaders in the field of liver disease. Dr. Liang conducted pioneering research in the field of viral hepatitis, including identifying and characterizing various HBV variants, defining a novel genetic element of hepatitis B virus, elucidating the biological functions of HBV X gene, developing in vitro systems to generate HCV-like particles for vaccine development, establishing culture systems for production of infectious HCV virus, elucidating the mechanisms of action of interferon and ribavirin in HCV therapy, creating transgenic mouse models to study hepatitis C, identifying important genetic markers in the outcome of HCV infection and treatment response, and discerning key steps in the pathogenesis of viral hepatitis and hepatocellular carcinoma. He has published more than 200 scientific papers, edited numerous books, and holds more than 10 patents.
NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link: http://bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx.
Choreographing the Tango between Hepatitis C Virus and Cells by Functional Genomic Approach (NIH Only)
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- 3rd Annual NIH Graduate & Professional School Fair
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- - Sponsored by the NIH Office of Intramural Training and Education (2010/11/18)
- - Category : Career Development/OITE
- Getting to Graduate School: Beginning with the question.
Why do you want to go to graduate school. This workshop will help participants determine what sort of graduate program would be the most appropriate for them. Additionally, the workshop covers the preparation of what is needed to be a successful applicant in graduate school; how to seek letters of recommendation, and choosing schools, and programs.
Speakers:
- Dr. Joel Oppenheim
- Dr. Nancy Schwartz
Public Health: From Admissions to Career Opportunities.
This workshop will provide you insight into knowing what is needed to be a successful candidate in applying to programs in public health and career opportunities. Public health careers offer something for everyone. Epidemiology and biostatistics involve mathematics and modeling. Environmental health includes a wide range of science skills. Health administration incorporates business and management skills. Health education involves skills required to develop community-wide prevention programs. Health policy includes an understanding of law-making processes.
Speakers:
- Jacqui Comshaw
- Allison Foster
- Michael Ward
- Dr. Joel Oppenheim
3rd Annual NIH Graduate & Professional School Fair
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- Optimizing iTRAQ for Complex Biological Samples
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- - Darryl Pappin, Cold Spring Harbor Laboratory (2010/11/18)
- - Category : Proteomics
Optimizing iTRAQ for Complex Biological Samples
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- NCI Town Hall Meeting - July 2010
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- - Harold Varmus, Director of the NCI (2010/11/18)
- - Category : Special
- Harold Varmus will convene a town hall meeting in the Main Auditorium of the Natcher Building at 3PM on Monday, July 12, after being sworn-in that morning as the 14th Director of the NCI. Following a brief and informal talk, he will answer questions from the audience and then greet NCI staff members and other attendees at a reception in the atrium of the auditorium.
NCI Town Hall Meeting - July 2010
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- Changing Management of Endometrial Cancer (NIH Only)
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- - David G. Mutch, M.D., Washington University School of Medicine (2010/11/18)
- - Category : NCI CCR Grand Rounds (NIH Only)
- Dr. David Mutch is the Judith and Ira Gall Professor of obstetrics and gynecology and the director of gynecologic oncology at the Washington University School of Medicine in St. Louis. He is a member of the Division of Gynecologic Oncology of the American Board of Obstetrics and Gynecology and serves as a reviewer for multiple medical journals related to women？？？s health and cancers of the female reproductive tract. He has authored or co-authored more than 200 peer-reviewed publications, as well as numerous book chapters on the subject as well.
Dr. Mutch has received multiple research grants from the American Cancer Society and the National Institutes of Health (NIH), among others. He is the principal investigator (PI) for the Gynecologic Oncology Group at Washington University and served as the program chair of the 2004 meeting of the Society of Gynecologic Oncologists. Dr. Mutch is the immediate past president of the Society of Gynecologic Oncologists. He is currently the co-PI on an NIH grant looking at defective DNA mismatch repair in endometrial cancers, as well as a co-PI on a recently awarded endometrial Special Project of Research Excellence (SPORE) grant. Dr. Mutch attended the Washington University School of Medicine, where he also completed his residency training. He underwent fellowship training at Duke University Medical Center in Durham, NC, before returning to Washington University in 1988. He recently received the Washington University School of Medicines Distinguished Alumni Award and is a member of Alpha Omega Alpha.
NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link: http://bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx.
Changing Management of Endometrial Cancer (NIH Only)
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- Handling Allegations of Research Misconduct (HHS-Only)
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- - Sally Rockey, Sally Amero, Maria Stagnitto, John Dahlberg, John Krueger (2010/11/18)
- - Category : ESA (HHS Only)
- Annual training for all NIH extramural staff in the proper handling of allegations of research misconduct.
http://odoerdb2.od.nih.gov/oer/training/esa/esa_training_20100713.htm
Handling Allegations of Research Misconduct (HHS-Only)
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- Travel HPOC Meeting for GovTrip (NIH-Only)
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- - Jennifer Martin (2010/11/18)
- - Category : Travel (NIH Only)
- We will be discussing common GovTrip issues and resolutions, reviewing functionality and answering questions regarding the system.
Travel HPOC Meeting for GovTrip (NIH-Only)
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- Solubility and Permeability Enhancement by New Nano-Micellar Natural Compounds
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- - Dr. Zhijun Liu, Louisiana State University Agricultural Center (2010/11/18)
- - Category : OCCAM Monthly Lecture Series
- The NCIs Office of Cancer Complementary and Alternative Medicine (OCCAM) invites you to view its monthly lecture series.
With the goal of informing the National Cancer Institute (NCI) community about the variety of ongoing research in cancer and complementary and alternative medicine (CAM), NCIs Office of Cancer Complementary and Alternative Medicine (OCCAM) has created a monthly lecture series on cancer CAM. These hour long lectures, occurring from 10 a.m. - 11 a.m. on the second Wednesday of each month, will feature a fifty minute presentation on a cancer CAM topic and allow ten minutes for questions.
For more information, visit
http://www.cancer.gov/cam/news_lectures.html
Solubility and Permeability Enhancement by New Nano-Micellar Natural Compounds
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- Introduction to Grant Writing II: Strategies for Writing Effective Training and Research Plans
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- - Dr. Stephen Korn, NINDS; and Dr. Sharon Milgram, OITE (2010/11/18)
- - Category : Career Development/OITE
- Most scientists who write grants agree that the planning, writing, and submission (and resubmission) process can be challenging. However, all agree that the more you understand about the process, the easier it is. Join us for this second session of a two-part introductory series on NIH grants. This workshop focuses on project development and the writing of effective training (for K Awards) and research plans. In addition, this workshop will examine strategies for re-submission.
http://www.training.nih.gov
Introduction to Grant Writing II: Strategies for Writing Effective Training and Research Plans
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- Workplace Ergonomics - How a Proper Workstation Set-up can Help Prevent Common Musculoskeletal Pain
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- - Robert Gillanders, PT, DPT. (2010/11/18)
- - Category : Focus on You Wellness
- Note: this event will not be shown live. It will be available from the Past-Events section as soon as possible.
Focus on You Wellness Lecture Series
How a proper workstation set-up can help prevent common musculoskeletal pain
For more information, visit
http://dats.ors.od.nih.gov/wellness/lecture.htm
Acrobat Slides
Workplace Ergonomics - How a Proper Workstation Set-up can Help Prevent Common Musculoskeletal Pain
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- NIH Directors Awards Ceremony 2010 (NIH-Only)
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- - Dr. Francis Collins (2010/11/18)
- - Category : NIH Only
- The NIH Directors Award will honor more than 300 NIH employees for the many outstanding ways in which they have enabled NIH to carry out its mission of turning discovery into health.
NIH Directors Awards Ceremony 2010 (NIH-Only)