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  • The National Cancer Advisory Board Meeting - February 2011
    • - NCI (2011/02/13)
    • - Category : National Cancer Advisory Board
    The 157th meeting of the National Cancer Advisory Board

    The National Cancer Advisory Board Meeting - February 2011

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  • NBS Travel HPOC Meeting - February 2011 (NIH Only)
    • - Jennifer Martin (2011/02/12)
    • - Category : Travel (NIH Only)
    Quarterly meeting of the NBS Travel HPOCs.

    NBS Travel HPOC Meeting - February 2011 (NIH Only)

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  • The Science of Research on Discrimination and Health (Day 2)
    • - NCI (2011/02/11)
    • - Category : Conferences
    Racial/ethnic discrimination is often identified as a contributor to racial/ethnic disparities in health but rarely examined in this context. The Applied Research and the Behavioral Research Programs of the Division of Cancer Control and Population Sciences (DCCPS) of the National Cancer Institute (NCI), National Institutes of Health (NIH) are sponsoring a three-day conference to examine the research and research methods for investigating the role of racial/ethnic discrimination in health. The specific purposes of the meeting are to (1) promote the science/research on racial/ethnic discrimination and its contribution to racial/ethnic disparities in health; (2) identify gaps in the research literature and areas for future research and/or NCI/NIH funding initiatives; and (3) increase awareness of the NCI？？？s interest in funding research in this topic area through the Program Announcement, The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (PA-080-083, PA-08-084, PA-08-085)

    The Science of Research on Discrimination and Health (Day 2)

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  • National Advisory Allergy and Infectious Diseases Council - February 2011 (NIH Only)
    • - Dr. Anthony S. Fauci, Director, NIAID, Dr. Carl Dieffenbach and Dr. Carole Heilman, Division Directors at NIAID (2011/02/11)
    • - Category : NIAID Council (NIH Only)
    The NAAIDC provides second level peer review of grant applications. In open session the council hears presentations from Dr. Fauci and another speaker.

    National Advisory Allergy and Infectious Diseases Council - February 2011 (NIH Only)

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  • Dendritic Spines and Linear Networks
    • - Rafael Yuste, M.D., PH.D., Departments of Biological Sciences and Neuroscience, Columbia University (2011/02/11)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    Inside the human brain, one region looms largest: the cerebral cortex. From thinking to memory, music to mental illness, the cortex controls much of human behavior. To understand this complex structure, Dr. Yuste has pioneered a combination of optical imaging and electrophysiological recording techniques to study patterns of neural activity. He is pursuing a reverse engineering strategy to determine the function of the cortical microcircuit, a basic element of cortex architecture. By first unraveling the dynamics of specific cortical microcircuits, and next the interactions between those microcircuits, he hopes to build a better understanding of how the whole cortex works.

    Dendritic Spines and Linear Networks

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  • STEP Symposium: Translating Research Advances for Health Care Providers and Patients: The Knowledge-to-Action Process
    • - David Chambers, Russ Glasgow, Beverly Green, George Isham and John Santa (2011/02/11)
    • - Category : STEP
    The clinical studies are done, the data are in - but why does it take so many years to translate clinical research into practice? Proven clinical strategies may not work in the community setting or may be slowly adopted by health care professionals and recipients. How do we move evidence-based clinical knowledge more effectively into public health and clinical community settings? This forum will explore the challenges and opportunities in implementation and dissemination of clinical research outcomes.

    For more information, visit
    http://esa.nih.gov/oer/training/step/step_training_20110208.htm

    STEP Symposium: Translating Research Advances for Health Care Providers and Patients: The Knowledge-to-Action Process

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  • Ths Science of Research on Discrimination and Health (Day 1)
    • - Vicki Shavers (2011/02/10)
    • - Category : Conferences
    Racial/ethnic discrimination is often identified as a contributor to racial/ethnic disparities in health but rarely examined in this context. The Applied Research and the Behavioral Research Programs of the Division of Cancer Control and Population Sciences (DCCPS) of the National Cancer Institute (NCI), National Institutes of Health (NIH) are sponsoring a three-day conference to examine the research and research methods for investigating the role of racial/ethnic discrimination in health. The specific purposes of the meeting are to (1) promote the science/research on racial/ethnic discrimination and its contribution to racial/ethnic disparities in health; (2) identify gaps in the research literature and areas for future research and/or NCI/NIH funding initiatives; and (3) increase awareness of the NCI？？？s interest in funding research in this topic area through the Program Announcement, The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (PA-080-083, PA-08-084, PA-08-085)

    For more information, visit
    http://conference.novaresearch.com/srdh/

    Ths Science of Research on Discrimination and Health (Day 1)

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  • The Science of Research on Discrimination and Health (Day 3)
    • - Vicki Shavers (2011/02/10)
    • - Category : Conferences
    Racial/ethnic discrimination is often identified as a contributor to racial/ethnic disparities in health but rarely examined in this context. The Applied Research and the Behavioral Research Programs of the Division of Cancer Control and Population Sciences (DCCPS) of the National Cancer Institute (NCI), National Institutes of Health (NIH) are sponsoring a three-day conference to examine the research and research methods for investigating the role of racial/ethnic discrimination in health. The specific purposes of the meeting are to (1) promote the science/research on racial/ethnic discrimination and its contribution to racial/ethnic disparities in health; (2) identify gaps in the research literature and areas for future research and/or NCI/NIH funding initiatives; and (3) increase awareness of the NCI？？？s interest in funding research in this topic area through the Program Announcement, The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (PA-080-083, PA-08-084, PA-08-085)

    The Science of Research on Discrimination and Health (Day 3)

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  • Grants.gov Quarterly Stakeholder Webcast - February 2011
    • - Grants.gov PMO, Philip Clark, PM (2011/02/08)
    • - Category : Grants.gov
    Grants.gov uses the quarterly webcasts to communicate the status of important program initiatives and operational status to stakeholders that include Applicants, Grantor Agencies, OMB, Congress and Third Party Vendors. The webcasts also offer stakeholders the opportunity to interact with the PMO and guests through live question and answer segments

    For more information, visit
    http://www.grants.gov

    Grants.gov Quarterly Stakeholder Webcast - February 2011

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  • Let Me Down Easy
    • - Anna Deavere-Smith (2011/02/08)
    • - Category : Special
    Please join us for a special appearance by Anna Deavere Smith, who will perform a short excerpt of Let Me Down Easy, her one-woman show about the human body, the human spirit, and the health care system. The full-length production is based on over 300 interviews and portrays more than 20 people and their experiences. Following the performance, Smith will share some of her thoughts on what she has learned in the process of creating this show.

    Let Me Down Easy

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  • Maturation of Functional GABAergic Microcircuits in the Developing Hippocampus
    • - Rosa Cossart, Ph.D., Mediterranean Institute of Neurobiology, France (2011/02/06)
    • - Category : Neuroscience
    Coordinated activation of neuronal assemblies features most physiological and pathological brain functions and carries a determinant role in proper network wiring during development. In the hippocampus and cortical formations, network function is strongly modulated by the action of GABAergic interneurons that comprise ~10-15% of the total neuronal population. These cells mediate inhibitory synaptic transmission in the adult brain and an impairment of selective subpopulations of GABAergic microcircuits most often leads to epileptogenesis. Research in Dr. Cossart？？？s lab is centred on the maturation of GABAergic microcircuits during brain development. They believe that understanding the major steps governing their proper wiring into cortical circuits will help to identify their functional implication in different network states including pathological disorders involving excessive synchrony between neurons. To describe cortical networks at the scale of microcircuits, they have developed a multidisciplinary research strategy that allows for a dynamic and global vision of the network but also for the single-cell level description of its key components. It combines multibeam two-photon calcium imaging of network dynamics in brain slices, targeted electrophysiological recordings, histology, and online data analysis (Cossart 2005; Goldin 2007; Cr？？pel 2007 ; All？？ne 2008). They are using genetically engineered mice where different GABAergic subpopulations are GFP-labeled and in particular genetic fate mapping approaches to target different functional assemblies of interneurons based on their spatial and temporal origins.

    NIH Neuroscience Seminar Series

    Maturation of Functional GABAergic Microcircuits in the Developing Hippocampus

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  • Should Women Who Want to Get Pregnant Be Allowed to Participate in Research?
    • - Margaret O. Little, PhD, Director and Senior Research Scholar, Kennedy Institute of Ethics; Associate Professor of Philosophy, Georgetown University (2011/02/06)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Ethics Rounds

    http://www.cc.nih.gov/about/news/grcurrent.html

    Should Women Who Want to Get Pregnant Be Allowed to Participate in Research?

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  • LUNCH AND LEARN PARENTING SEMINAR: WHAT TO DO WITH YOUR TEEN FOR THE SUMMER.
    • - Jennifer Alfonso, MBA, MSW, LCSW-C, LifeWork Strategies, Inc. (2011/02/06)
    • - Category : Parenting
    Summer break is an excellent opportunity to continue learning and exploring the world outside of the classroom. Activities such as volunteering, paid work and internships offer teens additional life skills and experiences. Attend this seminar for tips on talking to your teen about their summer plans, a discussion on the many types of summer break opportunities, and information on teen work permits and student service learning requirements.

    Acrobat Slides

    http://does.ors.od.nih.gov/childcare

    LUNCH AND LEARN PARENTING SEMINAR: WHAT TO DO WITH YOUR TEEN FOR THE SUMMER.

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  • The Transcription Factor PLZF Controls the Development of Mouse and Human Innate T Cells
    • - Derek SantAngelo (2011/02/06)
    • - Category : Immunology
    The Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an Annual Immunology Retreat.

    The Immunology Interest Group

    The Transcription Factor PLZF Controls the Development of Mouse and Human Innate T Cells

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  • Fluorescent Protease Biosensors Engineered from Fluorogen Activating Proteins
    • - Peter B. Berget, Ph.D., Carnegie Mellon University (2011/02/06)
    • - Category : Proteomics
    NIH Proteomics Interest Group Seminar Series

    Recently we described a new class of fluoromodules formed upon the non-covalent binding of a fluorogenic dye to a cognate protein partner. The protein-dye interaction significantly enhances the fluorescence quantum yield of the dye. The protein partners are variable domains of IgG molecules selected from a single-chain variable fragment (scFv) yeast surface-display library. These protein partners are called Fluorogen Activating Proteins (FAPs). We were intrigued by the fact that some of the FAPs selected to enhance the fluorescence of malachite green or dimethylindole red were solo variable heavy (VH) or variable light domains (VL), not connected to their opposite domain type in a standard scFv format (VH-VL).

    In my talk I will describe how investigations into these unusually formatted FAPs led us to discover several variable domain FAP combinations that can be used as platforms for engineering site-specific protease biosensors. I will describe the designed and synthesis of biosensors for members of several different families of proteases such as matrixmetalloproteinases, caspases, RNA virus proteases and neurotoxin proteases. Because these protease biosensors are genetically encoded, several different molecular modifications can be easily made to the biosensors depending on the desired application.

    For more information, visit
    http://proteome.nih.gov

    Fluorescent Protease Biosensors Engineered from Fluorogen Activating Proteins

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  • Demystifying Medicine - Staphylococcus: why and how does it still kill?
    • - Frank DeLeo (NIAID)and Alexandra Freeman (NIAID) (2011/02/05)
    • - Category : Demystifying Medicine
    This event will include the presentation of patients, pathology, diagnosis and therapy context of major disease problems and current research. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. These seminar series are primarily directed toward PhD students, clinicians and program managers. All students, fellows and staff are welcome, as well.

    For more information, visit
    http://www1.od.nih.gov/oir/DemystifyingMed

    Demystifying Medicine - Staphylococcus: why and how does it still kill?

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  • CC Grand Rounds: (1) Pharmacotherapy for Pediatric Obesity (2) Challenges of the Rising Incidence in Childhood Diabetes
    • - Jack Yanovski, MD, PhD and Kristina Rother, MD (2011/02/05)
    • - Category : Clinical Center Grand Rounds
    Clincal Center Grand Rounds

    Jack Yanovski, MD, PhD, Chief, Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, NICHD

    Kristina Rother, MD, Staff Clinician, Clinical Endocrinology Branch, NIDDK

    For more information, visit
    http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: (1) Pharmacotherapy for Pediatric Obesity (2) Challenges of the Rising Incidence in Childhood Diabetes

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  • From the Bench to the Field and Back: A Global Approach to Dengue and Influenza
    • - Eva Harris, Ph.D., Professor of Infectious Diseases and Director of the Center for Global Public Health at the University of California at Berkeley, and President of the Sustainable Sciences Institute (2011/02/05)
    • - Category : Wednesday Afternoon Lectures
    In this talk, Dr. Harris will discuss the approach she has developed over the last two decades of combining bench work at the University of California, Berkeley, with field work in Nicaragua to investigate the pathogenesis, immunology and epidemiology of dengue and influenza. She will describe the long-term pediatric cohort study ongoing in Managua, Nicaragua, and epidemiological insights that have been derived about dengue and influenza and possibly interactions between the two. She will also discuss her work on a dengue mouse model of antibody-dependent infection and lethal disease that allows mechanistic investigation of the role of natural and therapeutic antibodies in protection and pathogenesis, and how this interfaces with parallel studies of dengue immunology in human populations. Finally, this work underscores the importance of long-term collaborations in global health and partnerships for sustained scientific capacity building in developing countries.

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    From the Bench to the Field and Back: A Global Approach to Dengue and Influenza

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  • Demystifying Medicine - Estrogens: mood and postpartum depression
    • - Peter Schmidt (NIMH) and Alan DeCherney (NICHD) (2011/02/05)
    • - Category : Demystifying Medicine
    This event will include the presentation of patients, pathology, diagnosis and therapy context of major disease problems and current research. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. These seminar series are primarily directed toward PhD students, clinicians and program managers. All students, fellows and staff are welcome, as well.

    For more information, visit
    http://www1.od.nih.gov/oir/DemystifyingMed

    Demystifying Medicine - Estrogens: mood and postpartum depression

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  • National Advisory Research Resources Council - January 2011
    • - National Center for Research Resources (2011/02/02)
    • - Category : National Advisory Research Resources Council
    The January 25, 2011, meeting of the National Advisory Research Resources Council will feature discussion of the Scientific Management Review Board？？？s recommendation to develop a Translational Medicine and Therapeutics Center and the likely impact of the recommendation on other NCRR programs. Also planned are presentations on NCRR？？？s role in building connections among its programs through networking and collaboration, inclusion reporting for 2010, and an update on core consolidation activities. In addition, NCRR staff members will present Concept Clearances for consideration and approval by Council.

    http://www.ncrr.nih.gov/about_us/advisory_council/

    National Advisory Research Resources Council - January 2011

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