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  • SEER PI Meeting - November 2010 (Day 2)
    • - Surveillance Research Program - SEER (2010/12/16)
    • - Category : Conferences
    The SEER Meeting provides training and research information on cancer statistics to Cancer Tumor Registrars, Principal Investigators and personnel from the various Cancer Registries throughout the U.S.

    SEER PI Meeting - November 2010 (Day 2)

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  • Bridging Science, Treatment and Public Education of Anxiety Disorders
    • - NIMH (2010/12/16)
    • - Category : Conferences
    A Tribute to the Work of Jerilyn Ross

    Bridging Science, Treatment and Public Education of Anxiety Disorders

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  • Advances in Uterine Leiomyoma Research: 3rd NIH International Congress (Day 1)
    • - National Institutes of Health Office of Research on Womens Health (ORWH) (2010/12/16)
    • - Category : Conferences
    The 3rd NIH international congress on advances in uterine leiomyoma research will be sponsored by the Department of Health and Human Services, National Institutes of Health Office of Research on Women？？？s Health (ORWH), National Institute of Environmental Health Sciences (NIEHS), Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Cancer Institute (NCI), National Center for Research Resources (NCRR), National Institute of Nursing Research (NINR), Office of Women？？？s Health/Office of the Secretary, Agency for Healthcare Research and Quality (AHRQ), Centers for Disease Control and Prevention (CDC), Office of Women？？？s Health/Food and Drug Administration (FDA), Health Resources and Services Administration (HRSA).

    Introductory Remarks will be provided by Vivian W. Pinn, M.D., Associate Director for Research on Women？？？s Health and Director, Office of Research on Women？？？s Health, NIH; Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S., Director of the National Institute of Environmental Health Sciences and the National Toxicology Program, NIH; and Florence P. Haseltine, Ph.D., M.D., Director of the Center for Population Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH.

    The goal of this conference is to bring together researchers working in the fields of medicine, epidemiology, basic research, and therapeutics to foster an exchange of scientific information among members of the uterine leiomyoma research community. Participants will be drawn from academia, medicine, government, and industry.

    Topics to be covered include Clinical Management and Therapeutic Strategies, Epidemiology, Pathogenesis, Environmental Influences, Model Systems, Hormonal Regulation, and Molecular and (Epi)Genetic Characteristics.

    Advances in Uterine Leiomyoma Research: 3rd NIH International Congress (Day 1)

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  • Molecular Physiology of Sound Encoding at the Hair Cell Synapse
    • - Tobias Moser, M.D., University of Goettingen, Germany (2010/12/16)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    Dr. Mosers group focuses on the molecular physiology and pathology of the hair cell ribbon synapse. Molecular dissection and detailed physiological characterization of ribbon synapse function have only recently become possible using novel molecular and biophysical techniques. Dr. Moser combines single cell RT-PCR, immunohistochemistry of hair cells with auditory physiology (recordings of otoacoustic emissions, compound action potentials and auditory brainstem responses) and in-depth biophysical analysis of the hair cell ribbon synapse in normal and mutant mice. The biophysical approach includes patch-clamp and optical methods to investigate membrane currents, synaptic membrane turnover and stimulus-secretion coupling in hair cells from the mouse. The group has significantly contributed to understanding hair cell ribbon synapse function.

    http://neuroseries.info.nih.gov

    Molecular Physiology of Sound Encoding at the Hair Cell Synapse

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  • TRACO: Breast Cancer and Epigenetics
    • - F. Zia and M. Verma (2010/12/16)
    • - Category : TRACO
    For more information, visit
    http://ccr.cancer.gov/careers/traco.asp

    TRACO: Breast Cancer and Epigenetics

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  • Advances in Uterine Leiomyoma Research: 3rd NIH International Congress (Day 2)
    • - National Institutes of Health Office of Research on Womens Health (ORWH) (2010/12/16)
    • - Category : Conferences
    The 3rd NIH international congress on advances in uterine leiomyoma research will be sponsored by the Department of Health and Human Services, National Institutes of Health Office of Research on Women？？？s Health (ORWH), National Institute of Environmental Health Sciences (NIEHS), Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Cancer Institute (NCI), National Center for Research Resources (NCRR), National Institute of Nursing Research (NINR), Office of Women？？？s Health/Office of the Secretary, Agency for Healthcare Research and Quality (AHRQ), Centers for Disease Control and Prevention (CDC), Office of Women？？？s Health/Food and Drug Administration (FDA), Health Resources and Services Administration (HRSA).

    Introductory Remarks will be provided by Vivian W. Pinn, M.D., Associate Director for Research on Women？？？s Health and Director, Office of Research on Women？？？s Health, NIH; Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S., Director of the National Institute of Environmental Health Sciences and the National Toxicology Program, NIH; and Florence P. Haseltine, Ph.D., M.D., Director of the Center for Population Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH.

    The goal of this conference is to bring together researchers working in the fields of medicine, epidemiology, basic research, and therapeutics to foster an exchange of scientific information among members of the uterine leiomyoma research community. Participants will be drawn from academia, medicine, government, and industry.

    Topics to be covered include Clinical Management and Therapeutic Strategies, Epidemiology, Pathogenesis, Environmental Influences, Model Systems, Hormonal Regulation, and Molecular and (Epi)Genetic Characteristics.

    Advances in Uterine Leiomyoma Research: 3rd NIH International Congress (Day 2)

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  • The Grand Challenges of Hematopoietic Cell Transplantation (NIH Only)
    • - Frederick R. Appelbaum, M.D., Fred Hutchinson Cancer Research Center, Seattle, WA (2010/12/16)
    • - Category : NCI CCR Grand Rounds (NIH Only)
    Frederick R. Appelbaum received his M.D., from Tufts University School of Medicine. He completed his internship and residency at the University of Michigan Medical Center and his fellowship in medical oncology at the National Cancer Institute (NCI). He joined the Fred Hutchinson Cancer Research Center？？？s (FHCRC) scientific staff in 1978 and in 1988 became a full member of the FHCRC faculty and a professor of medicine in the Division of Oncology at the University of Washington. He has been senior vice president and director of the Clinical Research Division at FHCRC since 1993 and was named executive director of the Seattle Cancer Care Alliance and head of the Division of Medical Oncology at the University of Washington School of Medicine in 1998. He is a diplomat on the American Boards of Internal Medicine and Medical Oncology and is past chair of the Board of Scientific Advisors of NCI. In addition, he has been a board member of several scientific societies, including the American Society of Hematology, American Society of Clinical Oncology, American Society for Blood and Marrow Transplantation and is chair of the Leukemia Committee of the Southwest Oncology Group. Dr. Appelbaum served two terms as associate editor for Blood and also serves on the editorial boards of numerous scientific journals. Dr. Appelbaum is head of the Clinical Transplant Research Program in the FHCRC/University of Washington Cancer Consortium and principal investigator on several National Institutes of Health grants. He is the author of more than 800 scientific articles and was the lead author on the first paper to describe the successful use of autologous marrow transplantation. Dr. Appelbaum？？？s current research interests center on the biology and treatment of hematologic malignancies.

    NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. CME credit available via sign-up sheets in the lecture hall and at designated video-bridge sites only.

    The Grand Challenges of Hematopoietic Cell Transplantation (NIH Only)

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  • NIH Leave Bank Employee Briefing (NIH Only)
    • - NIH OHR (2010/12/16)
    • - Category : Human Resources (NIH Only)
    Provide employee information on the new leave bank

    NIH Leave Bank Employee Briefing (NIH Only)

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  • Careers in Science Education and Outreach: A "How To" Workshop
    • - Lori Conlan, PhD, Director, Office of Postdoctoral Services (2010/12/16)
    • - Category : Career Development/OITE
    Do you have a passion to take your scientific work, knowledge, and experience out into the community? Do you enjoy teaching? Would you like a career that can integrate both areas into one? Then this is the seminar for you! With the increasing need to engage the public with science and technology, many fellows have been asking, "How do I get a job in science education and outreach?"

    http://www.training.nih.gov

    Careers in Science Education and Outreach: A "How To" Workshop

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  • Careers in Regulatory Affiars: Second in the "How To" Series
    • - Lori Conlan, PhD, Director, Office of Postdoctoral Services (2010/12/16)
    • - Category : Career Development/OITE
    Regulatory affairs is a steadily growing career path. We will focus on ways that PhDs can participate in the regulation process to protect human, animal, and environmental health. This session will explore who does regulatory affirs (both in the government and beyond). what regularoty scientists are doing, what employers are looking for in successful candidates, and how to prepare yourselves for the transition to this career.

    http://www.training.nih.gov

    Careers in Regulatory Affiars: Second in the "How To" Series

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  • Imaging and Stimulating Human Brain Remodeling
    • - Heidi Johansen-Berg, Ph.D., , University of Oxford, United Kingdom (2010/12/16)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    Animal studies show that the adult brain shows remarkable plasticity in response to learning or recovery from injury. Non-invasive brain imaging techniques can be used to detect systems-level structural and functional plasticity in the human brain. This talk will focus on how brain imaging has allowed us to monitor healthy brains learning new motor skills and to assess how damaged brains recover. For example, structural and diffusion MRI shows that learning to juggle changes not only grey matter but also white matter in healthy brains. In patients recovering after a stroke to one side of their brain, functional MRI and transcranial magnetic stimulation provide evidence for increased recruitment of areas in the healthy side of the brain. Combining structural and functional approaches allows us to demonstrate that motor practice can functionally rescue regions that are structurally compromised following damage.

    New developments in brain stimulation raise exciting opportunities for manipulating brain remodelling. Using transcranial direct current stimulation (tDCS) to the motor cortex we can speed people？？？s learning of a new task, alter their brain chemistry, or temporarily improve hand function in stroke patients. FMRI identifies changes in cortical activity that may mediate these functional benefits. In future, imaging could be used to guide individually targeted brain stimulation to enhance recovery after damage.

    http://neuroseries.info.nih.gov

    Imaging and Stimulating Human Brain Remodeling

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  • TRACO: Cervical Cancer and Ovarian Cancer
    • - J. Schiller and C. Annunziata (2010/12/16)
    • - Category : TRACO
    For more information, visit
    http://ccr.cancer.gov/careers/traco.asp

    TRACO: Cervical Cancer and Ovarian Cancer

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  • Design and Development of Recombinant Vaccines for Cancer Therapy (NIH Only)
    • - Jeffrey Schlom, Ph.D. and James L. Gulley, M.D., Ph.D., F.A.C.P. (2010/12/16)
    • - Category : NCI CCR Grand Rounds (NIH Only)
    NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. CME credit available via sign-up sheets in the lecture hall and at designated video-bridge sites only.

    Design and Development of Recombinant Vaccines for Cancer Therapy (NIH Only)

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  • STEP Symposium - Health Care Reform and NIH (HHS Only)
    • - Barbara Woynarowska (2010/12/16)
    • - Category : STEP (HHS Only)
    Health Care and Education Affordability Reconciliation Act 2010 (Affordable Health Care for America Act) became law on March 30, 2010. Extensive discussion and media coverage have focused on the impact on health care services. Yet, news stories scarcely mentioned the role for NIH in enabling health care reform through scientific advances. This forum will describe provisions in the bill of interest to NIH and the potential use of NIH expertise in implementing the objectives of the Act. Will execution of the law require changes in programmatic and funding priorities? Come and learn what the future may hold for you.

    For more information, visit
    http://odoerdb2-1.od.nih.gov/oer/training/step/step_training_20101130.htm

    STEP Symposium - Health Care Reform and NIH (HHS Only)

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  • How to Make a Splash with Social Media without Getting Wet! (NIH Only)
    • - David Uejio and Jonh Grill (2010/12/16)
    • - Category : Human Resources (NIH Only)
    OHR Brown Bag: Professional Development

    How to Make a Splash with Social Media without Getting Wet! (NIH Only)

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  • Ethics and Participation in Multiple Studies
    • - Scott Halpern, MD, PhD, University of Pennsylvania School of Medicine (2010/12/16)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Ethics Rounds

    Scott Halpern, MD, PhD, Senior Fellow, Center for Bioethics, University of Pennyslvania and Assistant Professor of Medicine and Epidemiology, University of Pennsylvania School of Medicine

    Ethics and Participation in Multiple Studies

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  • Telomerase and the Consequences of Telomere Dysfunction
    • - Carol Greider, Ph.D., Nobel Laureate, Johns Hopkins School of Medicine (2010/12/16)
    • - Category : Wednesday Afternoon Lectures
    Telomeres protect chromosome ends from being recognized as DNA damage and chromosomal rearrangements. Conventional replication leads to telomere shortening, but telomere length is maintained by the enzyme telomerase that synthesizes telomere sequences de novo onto chromosome ends. Telomerase is specialized reverse transcriptase, requiring both a catalytic protein and an essential RNA component. In the absence of telomerase, telomeres shorten progressively as cells divide, and telomere function is lost. For this reason, telomerase is required for cells that undergo many rounds of divisions, especially tumor cells and some stem cells. The Greider lab is focused understanding telomerase and cellular and organismal consequences of telomere dysfunction. We use biochemistry, yeast and mice to examine telomere function. We generated telomerase null mice that are viable and show progressive telomere shortening for up to six generations. In the later generations, when telomeres are short, cells die via apoptosis or senescence. Crosses of these telomerase null mice to other tumor prone mice show that tumor formation can be greatly reduced by short telomeres. We also are using our telomerase null mice to explore the role of telomerase stem cells and aging. In human families, Telomerase mutations cause autosomal dominant dyskeratosis congenita and the associated bone marrow failure. We have developed a strain of mice that are haploinsufficient for telomerase and show many hallmarks of dyskeratosis congenita and age related degenerative disease. Our lab is focused on understanding how short telomeres cause these diseases as well as the mechanisms that regulate telomere length equilibrium.

    Lecture Objectives:
    1. Understand the role of telomerase in telomere length
    2. Understand the effect of short telomeres in cancer cell growth
    3. Discuss role of telomere shortening in age related disease

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Telomerase and the Consequences of Telomere Dysfunction

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  • Targeting CXCR4 in WHIM Syndrome
    • - Philip Murphy (2010/12/16)
    • - Category : Immunology
    The Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an Annual Immunology Retreat.

    The Immunology Interest Group

    Targeting CXCR4 in WHIM Syndrome

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  • NIH/AHRQ Conference on Methodological Challenges in Comparative Effectiveness Research - Day 1
    • - NIH & AHRQ (2010/12/16)
    • - Category : Conferences
    The conference will make use of case studies that pose difficult questions about what kinds of research, methods and analyses should be used to address limitations in current evidence for interventions and tests being examined by decision-making bodies. The cases will address a variety of important comparative effectiveness research questions facing U.S. researchers, care providers, health systems, and patients. This conference is being convened at a historic moment for the biomedical, clinical, biostatistical, research design and health services research communities. With the passage of the Patient Protection and Affordable Care Act (PPACA), the nation stands at a critical juncture, as it ramps up efforts to streamline the delivery of high quality healthcare, bend the cost curve and ensure improved health outcomes.

    NIH/AHRQ Conference on Methodological Challenges in Comparative Effectiveness Research - Day 1

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  • GOT PARENTING STRESS???
    • - Eliane Herdani, MS, LCPC, LifeWork Strategies, Inc. (2010/12/16)
    • - Category : Parenting
    Does parenting ever make you feel overwhelmed or stressed out? Parenting is one of lifes most joyful and rewarding experiences, but there are times when the demands of work and family life can be stressful. Attend this seminar to learn techniques for managing parental stress, how to identify stressors and triggers, strategies for boosting your own energy and resilience, as well as how to enhance and utilize your resources as a working parent.

    Acrobat Slides

    GOT PARENTING STRESS???

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