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  • Demystifying Medicine - Sleep: mechanisms, disorders and circadian rhythm
    • - Dr. David Dinges and Dr. Michael Menaker (2011/01/21)
    • - Category : Demystifying Medicine
    This event will include the presentation of patients, pathology, diagnosis and therapy context of major disease problems and current research. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components presented by NIH staff and invitees. These seminar series are primarily directed toward PhD students, clinicians and program managers. All students, fellows and staff are welcome, as well.

    For more information, visit
    http://www1.od.nih.gov/oir/DemystifyingMed

    Demystifying Medicine - Sleep: mechanisms, disorders and circadian rhythm

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  • How Telomeres Protect Chromosome Ends from Engaging the DNA Damage Response
    • - Dr Sandy Chang, Yale University (2011/01/21)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group

    How Telomeres Protect Chromosome Ends from Engaging the DNA Damage Response

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  • CC Grand Rounds: HIV, HCV, and the Liver: Struggles and Solutions
    • - Colleen Hadigan, MD, MPH, and Shyam Kottilil (2011/01/21)
    • - Category : Clinical Center Grand Rounds
    Clincal Center Grand Rounds

    Colleen Hadigan, MD, MPH, Staff Clinician, Laboratory of Immunoregulation, NIAID

    Shyam Kottilil, Staff Clinician, Immunopathogenesis Section, Laboratory of Immunoregulation, NIAID

    For more information, visit
    http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: HIV, HCV, and the Liver: Struggles and Solutions

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  • NSABB Public Consultation on Guidance for Enhancing Personnel Reliability and Strengthening the Culture of Responsibility at the Local Level
    • - National Science Advisory Board for Biosecurity (2011/01/20)
    • - Category : National Science Advisory Board for Biosecurity
    The NSABB is hosting a public consultation to obtain input from the scientific community regarding strategies for enhancing personnel reliability and strengthening the culture of responsibility at research facilities that conduct research with dangerous pathogens. The discussion will inform NSABB deliberations and ultimately the development of an NSABB report on the topic.

    The meeting will focus on five topics: 1) Engaged institutional leadership for promoting biosecurity, personnel reliability, and a culture of responsibility; 2) Encouraging biosecurity awareness and promoting responsible conduct in the laboratory through communication, lab rapport, and a strong sense of team; 3) Peer reporting of concerning behaviors; 4) Addressing impediments to disclosure of negative information about job candidates; and 5) Assessment of effectiveness and impact of practices for strengthening personnel reliability and culture of responsibility. Each session will include remarks from panelists as well as ample time for input from meeting attendees.

    NSABB Public Consultation on Guidance for Enhancing Personnel Reliability and Strengthening the Culture of Responsibility at the Local Level

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  • NIH PROMIS 2011 - Advancing PRO Science in Clinical Research and Patient Care
    • - NIH PROMIS Working Group (2011/01/20)
    • - Category : Conferences
    A presentation on Patient-Reported Outcomes Measurement Information System (PROMIS) and how PROMIS enables researchers and clinicians to use the best possible measures of self-reported health status.

    For more information, visit
    http://www.nihpromis.org

    NIH PROMIS 2011 - Advancing PRO Science in Clinical Research and Patient Care

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  • Resolution Revolution Positive Lifestyle Changes
    • - Terry Bowers (2011/01/15)
    • - Category : Focus on You Wellness
    Focus on You Wellness Lecture Series

    For more information, visit
    http://dats.ors.od.nih.gov/wellness/lecture.htm

    Resolution Revolution Positive Lifestyle Changes

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  • OHR All Hands Meeting - January 2011 (NIH Only)
    • - Chris Major and Phil Lenowitz (2011/01/15)
    • - Category : Human Resources (NIH Only)
    The OHR All Hands Meeting is an annual meeting with senior leadership to discuss the strategic goals with the OHR staff.

    OHR All Hands Meeting - January 2011 (NIH Only)

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  • Great Teachers: Sickle Cell Disease and Transfusion Therapy: Current Controversies
    • - Kim Smith-Whitley, MD (2011/01/15)
    • - Category : Clinical Center Grand Rounds
    Contemporary Clinical Medicine: Great Teachers

    Kim Smith-Whitley, MD, Associate Professor of Pediatrics, University of Pennysylvania School of Medicine; Clinical Director, Division of Hematology, and Director, Comprehensive Sickle Cell Center, Childrens Hospital of Philadelphia

    http://www.cc.nih.gov/about/news/grcurrent.html

    Great Teachers: Sickle Cell Disease and Transfusion Therapy: Current Controversies

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  • Recognition of danger signals and cytoplasmic DNA by inflammasomes
    • - Eicke Latz (2011/01/15)
    • - Category : Immunology


    The Immunology Interest Group

    Recognition of danger signals and cytoplasmic DNA by inflammasomes

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  • Do Scientists Understand the Public?
    • - Chris Mooney, Science and Political Journalist (2011/01/14)
    • - Category : NCCAM Lectures
    The Complementary and Integrative Medicine Consult Service lecture series sponsored by NCCAM provides NIH clinical center staff with the opportunity to learn more about how the integration of various complementary and alternative medicine treatments can affect approaches in the research and practice for medicine.

    For more information, visit
    http://nccam.nih.gov/research/consultservice/past.htm

    Do Scientists Understand the Public?

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  • STEP Symposium: From Amyblyopia to Zits: A Health Fair Forum (HHS Only)
    • - John Glowa, James Witter, Gordon Hughes, Richard Sherry, Mark Gourley, John DiGiovanna, Michael Kozak, Wadih Zein, Stephen Wank, Pamela Stratton, Merrill Mitler, Andrea Beckel-Mitchener and Andrew Monjan (2011/01/14)
    • - Category : STEP (HHS Only)
    Do you find it difficult to stand up because the room is spinning? Do your spouses fingers turn purple for no reason? Do you wonder why shingles have been making a comeback? Come to the Health Fair to learn more about a range of commonly experienced but not commonly understood conditions. This trans-NIH forum will use a unique format to explore the science, symptoms and treatment options for a dozen such ailments. The forum will include short presentations, as well as informational booths to discuss specifics and recent breakthroughs. Come hear whats new, whats changed, and whats on the horizon.

    For more information, visit
    http://odoerdb2-1.od.nih.gov/oer/training/step/step_training_20110111.htm

    STEP Symposium: From Amyblyopia to Zits: A Health Fair Forum (HHS Only)

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  • Dr. Martin Luther King, Jr. Observance (NIH-Only)
    • - Cato T. Laurencin, M.D., Ph.D. (2011/01/14)
    • - Category : Black History Observance (NIH Only)
    NIH 2011 Dr. Martin Luther King, Jr. Birthday Observance

    Dr. Martin Luther King, Jr. Observance (NIH-Only)

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  • Resistant Malaria Treated by a Mediation from Asia to Africa
    • - Dr. Jean-Herv？？ Bradol (2011/01/13)
    • - Category : Wednesday Afternoon Lectures
    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Resistant Malaria Treated by a Mediation from Asia to Africa

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  • Understanding the immune system: lessons from moviemakin and modeling
    • - Ronald Germain (2011/01/13)
    • - Category : Immunology
    The Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an Annual Immunology Retreat.

    The Immunology Interest Group

    Understanding the immune system: lessons from moviemakin and modeling

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  • Mammalian Circadian Clock and Metabolism-the Epigenetic Link
    • - Prof. Paolo Sassone-Corsi (2011/01/13)
    • - Category : Brain & Obesity
    NIDDK brain and obesity intermural lecture series

    Mammalian Circadian Clock and Metabolism-the Epigenetic Link

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  • National Cancer Institute Town Hall Meeting - January 2011
    • - Dr. Harold Varmus, Director, National Cancer Institute (2011/01/13)
    • - Category : Special
    Harold Varmus will convene a town hall meeting in the Main Auditorium of the Natcher Building at 2:30PM on Monday, January 10, to discuss developments that have occurred during the first six months of his tenure as NCI Director.

    National Cancer Institute Town Hall Meeting - January 2011

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  • Should Family Members Be Present at Clinical Rounds?
    • - Lee Goldman, Columbia University and Henry Masur, Critical Care Medicine Department, NIH (2011/01/09)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Ethics Rounds

    Lee Goldman, MD, MPH,
    Executive Vice President, Health and Biomedical Sciences and Dean of the Faculties of Health Sciences and Medicine, Columbia University College of Physicians and Surgeons.

    Case Presenter:
    Henry Masur, MD, Chief, Critical Care Medicine Department

    For more information, visit
    http://www.cc.nih.gov/about/news/grcurrent.html

    Should Family Members Be Present at Clinical Rounds?

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  • Seeing is Believing: A Gene Therapy Success
    • - Jean Bennett, M.D., Ph.D., University of Pennsylvania (2011/01/08)
    • - Category : Wednesday Afternoon Lectures
    Gene therapy has the potential to reverse disease or prevent further deterioration of vision in patients with incurable inherited retinal degeneration. The demonstration of safe and stable recovery of retinal/visual function in 12 children and adults with Leber congenital amaurosis (LCA) due to RPE65 mutations in a trial being carried out at The Children？？？s Hospital of Philadelphia (CHOP), and encouraging results from four other clinical trials for LCA-RPE65 provide great hope for people with other more common blinding diseases. This presentation will describe the animal studies that led to the clinical trials and the latest safety and efficacy results in the LCA-RPE65 clinical trial being held at CHOP. This Phase 1-2 study is now >3 years past initiation. In addition, it will describe some of the challenges presented by the nature of the targeted disease itself, hurdles that have been navigated in order to conduct the study, and issues of importance for eventual approval of gene augmentation as a therapy for LCA and other blinding diseases.

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Seeing is Believing: A Gene Therapy Success

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  • Basal Ganglia Mechanisms of Behavioral Plasticity
    • - David Perkel, Ph.D., University of Washington (2011/01/06)
    • - Category : Neuroscience
    Neuroscience Seminar Series

    Vocal learning in songbirds is an experimentally accessible model system in which to study the neural mechanisms of learning. Juvenile birds memorize song(s) from an adult tutor and then use auditory feedback from their own songs to compare with their memory of the tutor song(s). This comparison guides a process of motor learning; through practice, juvenile birds gradually learn to produce a highly stereotyped song that resembles the tutor song. Extensive research has investigated the underlying neural circuits that are involved in song learning and production. The Perkel lab uses a variety of electrophysiological, anatomical and behavioral approaches to probe the neural mechanisms that mediate song learning and song behavior.

    For more information, visit
    http://neuroseries.info.nih.gov

    Basal Ganglia Mechanisms of Behavioral Plasticity

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  • Sex Differences in Drug Abuse: The Role of Estradiol
    • - Jill B. Becker, PhD (2010/12/24)
    • - Category : BSSR Lecture Series
    BSSR Lecture Series

    There are sex differences in many motivated behaviors, including the motivation to take drugs of abuse. In females, rapid effects of estradiol on the ascending dopamine (DA) system enhance the females motivation to take cocaine and other drugs of abuse. These effects of estradiol can be studied behaviorally and neurochemically when looking at the response to psychomotor stimulant drugs such as cocaine and amphetamine. For example, we have found that female rats exhibit greater behavioral sensitization to cocaine, acquire cocaine self-administration more rapidly, and work harder for access to cocaine than males. Estradiol enhances these sex differences. In the striatum and nucleus accumbens, estradiol rapidly potentiates stimulated DA release of female rats. Results from experiments investigating the mechanisms mediating this effect of estradiol will also be discussed.

    Sex Differences in Drug Abuse: The Role of Estradiol

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