전체 8345
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- Evolution and Biological Systems
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- - Marx, Christopher.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Evolution and Medicine
- - Marx, Christopher.
- Microbes present an opportunity to study evolution on a small scale, both in time and space ？？？ and to address particularly vexing biological questions such as how organisms adapt to complex, changing environments. An emerging leader in the field of experimental evolution, Dr. Marx approaches this question by studying the evolution of physiological systems in microbial populations.
Lecture series presented by National Institute of General Medical Sciences, the Office of Science Education, and the National Human Genome Research Institute. For more information, visit
http://www.nigms.nih.gov/News/Meetings/EvolutionSeries2008
Evolution and Biological Systems
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- Great Teachers - Fifth Annual John Laws Decker Memorial Lecture: Solving the Inflammation Puzzle One Patient at a Time
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- - Gallin, John I.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Clinical Center Grand Rounds
- - Gallin, John I.
- The Decker Lecture honors the legacy of Dr. John Decker, who served as CC director from 1983-1990. The lecture is presented by the recipient of the NIH Distinguished Clinical Teachers Award, which is the highest honor bestowed collectively on an NIH senior clinician, staff clinician or tenure-track/tenured clinical investigator by the NIH clinical fellows. The award recognizes excellence in mentoring health-care professionals, excellence in teaching on issues related to direct patient care, and outstanding contributions to the advancement of clinical research.
John I. Gallin, MD
Director, NIH Clinical Center
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
Great Teachers - Fifth Annual John Laws Decker Memorial Lecture: Solving the Inflammation Puzzle One Patient at a Time
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- Electronic Health Records
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- - Dupree, Dorothy. (2010/11/18)
- - Category : CMS - Centers for Medicare & Medicaid Services
- CMS Medicine Dish Series
Electronic Health Records
We are pleased to present the next in our monthly satellite broadcast series created for providers in Indian Country. These programs serve as a path to open communication, providing information and promoting discussion about Medicare, Medicaid and State Children？？？s Health Insurance Programs (SCHIP), and other issues important to the health of our people.
A Panel will provide the information on:
？？？An Overview of the importance of Electronic Health Records and HHS initiatives
？？？IHS experiences with EHR and important new developments with the RPMS
？？？How CMS is working with EHR and what you can expect for CMS programs
The speakers will be:
？？？Howard Hays, MD - Indian Health Service
？？？Paul X. Donohoe ？？？ Centers for Medicare & Medicaid Services
？？？Karen Bell ？？？ Office of the Secretary
？？？Dorothy Dupree, Host and Moderator ？？？ Centers for Medicare & Medicaid Services
QUESTIONS CAN BE ASKED DURING THE BROADCAST BY CALLING 1-800-953-2233.
Materials related to this broadcast will be posted on the CMS AI/AN website at http://www.cms.gov under American Indian Alaska Native Center.
Electronic Health Records
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- Mechanisms of Leukocyte Recruitment in Inflammation
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- - Kubes, Paul.
National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18) - - Category : Immunology
- - Kubes, Paul.
- Dr. Paul Kubes？？？ major interests lie in models of Acute & Chronic Inflammation, including how different leukocytes (neutrophils, lymphocytes, etc.) traffic to sites of inflammation. The work of his laboratory combines intravital microscopy and functional studies to provide new insights into responses to infection and into mechanisms regulating inflammation with a special focus on models of human disease. Recent work includes studies of the role of Toll Receptors in the initiation of inflammation, the effects of PI3 kinase pathways in regulating cell trafficking and the role of mast cells in cytokine responses and inflammation.
Dr. Kubes is an exciting speaker and his talk is sure to be filled with beautiful pictures of the immune response in action!
For more information, visit
The Immunology Interest Group
Mechanisms of Leukocyte Recruitment in Inflammation
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- Tribute to John William Daly: A Life Dedicated to Chemistry in Nature
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- - Laboratory of Bioorganic Chemistry (National Institute of Diabetes and Digestive and Kidney Diseases) (2010/11/18)
- - Category : Special
- Colleagues, friends and family will celebrate the life and 50-year career of NIH Scientist Emeritus John W. Daly, Ph.D., who died March 5, 2008, in Rockville, MD, at the age of 74. He had pancreatic cancer. Daly was an international leader in chemical and pharmacological research, especially in the fields of drug metabolism, biologically active natural products, and adenosine receptors. Daly expanded the boundaries of chemistry and changed the course of research in pharmacology. He was a world authority on amphibian alkaloids and expert in many areas of natural products. The twenty-six classes of alkaloids he discovered have had a major impact on knowledge of how the nervous system functions and how drugs interact with the nervous system.
Tribute to John William Daly: A Life Dedicated to Chemistry in Nature
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- DDM - Workforce Diversity (NIH Only)
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- - Samuel Betances, Ph.D. (2010/11/18)
- - Category : DDM Seminar Series (NIH Only)
- 2007-2008 Deputy Director for Management (DDM) Seminar Series
Samuel Betances, Ph.D.
Author of Ten Steps to the Head of the Class: A Challenge to Students and Communicating Diversity: Powerful, Practical, Persuasive Pointers to Get the Job Done
This seminar is one of many efforts at the NIH in striving for management excellence and is designed to bring outstanding speakers to the NIH to discuss leadership and administrative management topics. It will provide administrative and scientific communities with the opportunity to meet with each other to discuss and exchange ideas on the topics presented.
The DDM Seminar Series is open to all NIH employees and there is no need to pre-register for the event.
http://www.ddmseries.od.nih.gov
DDM - Workforce Diversity (NIH Only)
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- Depression and Osteoporosis; the Magnitude of Bone Loss is Substantial
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- - Cizza, Giovanni.
National Institutes of Health (U.S.). Womens Health Special Interest Group. (2010/11/18) - - Category : Womens Health
- - Cizza, Giovanni.
- Womens Health Special Interest Group (WHSIG)
Intramural Program on Research on Womens Health
Sponsored by the NIH Office of Intramural Research
and the NIH Office of Research on Womens Health.
Come join your fellow NIH colleagues in a scientific exchange on issues related to the biology and pathology of sex and gender differences and effects on womens health.
For more information, visit
http://orwh.od.nih.gov
Depression and Osteoporosis; the Magnitude of Bone Loss is Substantial
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- HSPD-12/NED Information Session (NIH Only)
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- - Richard Taffet, HSPD-12 Program Manager and Jeff Erickson, NED Program Manager (2010/11/18)
- - Category : NIH Only
- This three-hour information session covers Homeland Security Presidential Directive (HSPD) 12 and changes being made to the NIH Enterprise Directory (NED). This session will also cover the new ID badging process at NIH and the role of Administrative Officers as ？？？Sponsors？？？ in the new process.
Prior to attending the session, a pre-work module should be completed online at http://www.idbadge.nih.gov/training/nedweb.asp. Please be sure to bring your signed certificate to the information session.
DPSAC Appointment Guide: http://www.idbadge.nih.gov/resources/publications.asp
NIH ID Badge Handbook: http://www.idbadge.nih.gov/resources/publications.asp
Badging Table: http://www.idbadge.nih.gov/badge/applying.asp
2866 Form: http://forms.nih.gov/adobe/personnel/NH2866.PDF
Instructions: http://forms.nih.gov/adobe/personnel/NH2866-instr.PDF
HSPD-12/NED Information Session (NIH Only)
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- Surgeon Generals Conference on Preventing Preterm Birth (Day 1)
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- - Surgeon Generals Conference on Preventing Preterm Birth
National Institute of Child Health and Human Development (U.S.) (2010/11/18) - - Category : Conferences
- - Surgeon Generals Conference on Preventing Preterm Birth
- Preterm birth remains one of the most complicated and difficult research and public health issues in obstetrics and pediatrics. Nearly 12 percent of all babies born in the United States are born preterm, and this rate continues to rise. To underscore the importance of this problem, the U.S. Congress passed the Prematurity Research Expansion and Education for Mothers who Deliver Infants Early (PREEMIE) Act (P.L. 109-450), which was signed by the President in December 2006.
In addition to encouraging more research on this topic and working to establish an evidence-based standard of care for pregnant women at risk of preterm labor, the PREEMIE Act also mandates a Surgeon General？？？s conference to address the growing problem of preterm birth. In 2007, the Office of the Surgeon General named the NICHD as its scientific lead for this Conference on the Prevention of Preterm Birth.
The two-day conference will be held on June 16-17, 2008, at the Bethesda North Marriott Hotel and Convention Center in Bethesda, Maryland. The Office of the Surgeon General and the NICHD have invited experts from the nation？？？s scientific, medical, public health, public policy, and community sectors to collaborate on developing a national agenda and action plan aimed at preventing preterm birth.
At the first day of the conference, June 16, 2008, invitees in workgroups will collaborate to develop a draft national agenda and action plan. The second day of the conference is open to interested members of the public and will focus on gathering input and suggestions on the draft agenda and plan. The conference will end with a formal presentation of the final national agenda and action plan to Rear Admiral Steven K. Galston, M.D., M.P.H., Acting Surgeon General of the United States.
For more information, visit
http://www.nichd.nih.gov/external.cfm?theURL=https://secure.palladianpartners.com/SurgeonGeneralPrivate
Surgeon Generals Conference on Preventing Preterm Birth (Day 1)
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- Surgeon Generals Conference on Preventing Preterm Birth (Day 2)
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- - Surgeon Generals Conference on Preventing Preterm Birth
National Institute of Child Health and Human Development (U.S.) (2010/11/18) - - Category : Conferences
- - Surgeon Generals Conference on Preventing Preterm Birth
- Preterm birth remains one of the most complicated and difficult research and public health issues in obstetrics and pediatrics. Nearly 12 percent of all babies born in the United States are born preterm, and this rate continues to rise. To underscore the importance of this problem, the U.S. Congress passed the Prematurity Research Expansion and Education for Mothers who Deliver Infants Early (PREEMIE) Act (P.L. 109-450), which was signed by the President in December 2006.
In addition to encouraging more research on this topic and working to establish an evidence-based standard of care for pregnant women at risk of preterm labor, the PREEMIE Act also mandates a Surgeon General？？？s conference to address the growing problem of preterm birth. In 2007, the Office of the Surgeon General named the NICHD as its scientific lead for this Conference on the Prevention of Preterm Birth.
The two-day conference will be held on June 16-17, 2008, at the Bethesda North Marriott Hotel and Convention Center in Bethesda, Maryland. The Office of the Surgeon General and the NICHD have invited experts from the nation？？？s scientific, medical, public health, public policy, and community sectors to collaborate on developing a national agenda and action plan aimed at preventing preterm birth.
At the first day of the conference, June 16, 2008, invitees in workgroups will collaborate to develop a draft national agenda and action plan. The second day of the conference is open to interested members of the public and will focus on gathering input and suggestions on the draft agenda and plan. The conference will end with a formal presentation of the final national agenda and action plan to Rear Admiral Steven K. Galston, M.D., M.P.H., Acting Surgeon General of the United States.
For more information, visit
http://www.nichd.nih.gov/external.cfm?theURL=https://secure.palladianpartners.com/SurgeonGeneralPrivate
Surgeon Generals Conference on Preventing Preterm Birth (Day 2)
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- Promotion of Homologous Recombination and Genomic Stability by RAD51AP1
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- - Wiese, Claudia.
National Institutes of Health (U.S.). DNA Repair Interest Group. (2010/11/18) - - Category : DNA Repair
- - Wiese, Claudia.
- Dr. Claudia Wiese, Lawrence
Berkeley National Lab, Promotion of homologous recombination and genomic stability by RAD51AP1
The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.
For more information, visit the
DNA Repair Interest Group
Acrobat Slides
Promotion of Homologous Recombination and Genomic Stability by RAD51AP1
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- National Cancer Advisory Board - June 2008 (Day 1)
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- - United States. National Cancer Advisory Board. Meeting (2010/11/18)
- - Category : National Cancer Advisory Board
- This is a regularly scheduled meeting of the National Cancer Advisory Board (NCAB).
National Cancer Advisory Board - June 2008 (Day 1)
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- Division of Labor at the Eukaryotic Replication Fork
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- - Stephanie Nick McElhinny, National Institute of Environmental Health Sciences (2010/11/18)
- - Category : DNA Repair
- Dr. Stephanie Nick McElhinny, NIEHS, Division of labor at the
eukaryotic DNA replication fork
Dr. Thomas Hollis, Wake Forest University Health Sciences, Structure of TREX1 and TREX2
Dr. Claudia Wiese, Lawrence Berkeley National Lab, Promotion of homologous recombination and genomic stability by RAD51AP1
The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.
For more information, visit the
DNA Repair Interest Group
Acrobat Slides
Division of Labor at the Eukaryotic Replication Fork
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- Recombinant DNA Advisory Committee (RAC) June 2008 - Day 1
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- - National Institutes of Health (U.S.). Recombinant DNA Advisory Committee. (2010/11/18)
- - Category : Recombinant DNA Advisory Committee
- The RAC is a technical committee whose goal is to consider the current state of knowledge and technology regarding recombinant DNA. This includes review of human gene transfer trials, and an assessment of the ability of DNA recombinants to survive in nature and the potential for transfer of genetic material to other organisms. It also considers hypothetical hazards and methods for monitoring and minimizing risks. Approximately one-third of the 15 members do not have scientific expertise but represent public interests and attitudes. This balance is intended to provide a forum for open public debate of social and scientific issues attendant to recombinant DNA research. The RAC has been overwhelmingly successful in achieving this goal.
For more information, visit the
Recombinant DNA Advisory Committee (RAC) Conference Web Site
Recombinant DNA Advisory Committee (RAC) June 2008 - Day 1
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- Introducing RCDC: the NIH Research, Condition, and Disease Categorization System
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- - Krensky, Alan.
National Institutes of Health (U.S.). Office of Portfolio Analysis and Strategic Initiatives. (2010/11/18) - - Category : Special
- - Krensky, Alan.
- A public introduction to the NIH Research, Condition, and Disease Categorization System. A brief presentation by the NIH Office of Portfolio Analysis and Strategic Initiatives (OPASI) followed by a Q&A session.
Introducing RCDC: the NIH Research, Condition, and Disease Categorization System
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- Getting at why people Change: Considerations of Genetics and Psychosocial Theory in Health Behavior Change: Is It All In Your Head or In Your Genes?
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- - Bouchard, Claude.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Special
- - Bouchard, Claude.
- SPRING 2008 SYMPOSIA SERIES ON MECHANISMS OF BEHAVIOR CHANGE
Organizing Agencies: AHRQ, NCI, NIAAA, NIDA, OBSSR
For more information, visit
http://www.niaaa.nih.gov/NewsEvents/Conferences/changesymposia08.htm
Getting at why people Change: Considerations of Genetics and Psychosocial Theory in Health Behavior Change: Is It All In Your Head or In Your Genes?
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- Chemokine Receptors in the Differentiation of Human CD4+ Effector/Memory T Cells
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- - Farber, Joshua.
National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18) - - Category : Immunology
- - Farber, Joshua.
- Josh Farbers research has focused on lymphocyte-active chemokines and their receptors. In early work, his laboratory discovered the major Th1 chemokine CXCL9 (Mig) and several critical T cell chemokine receptors, including CCR6, CXCR6, and CCR9A/B. In 1997, in collaboration with Ed Berger and Keith Peden, he showed that CXCR6 is a coreceptor for SIV and certain strains of HIV. In more recent work he has been investigating
chemokine receptor signaling and the epigenetics of chemokine receptor expression on human lymphocytes, and using chemokine receptor patterns to study the differentiation of human CD4+ effector/memory T cells. The latter studies have revealed that CCR5 and CCR2 identify subsets of potentially long-lived, highly differentiated effector memory T cells, so-called first responders, and that CCR6 is the chemokine receptor found on all Th17 cells. Currently, his laboratory is investigating the
importance of CCR6 in models of Th17-mediated disease. Come hear about these and other exciting findings from one of NIHs own.
For more information, visit
The Immunology Interest Group
Chemokine Receptors in the Differentiation of Human CD4+ Effector/Memory T Cells
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- Normal and Neoplastic Stem Cells
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- - Weissman, Irving L.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Wednesday Afternoon Lectures
- - Weissman, Irving L.
- Following embryonic development, most of our tissues and organs
are continuously regenerated from tissue/organ specific stem cells. The
principal property that distinguishes such stem cells from their daughter cells
is self-renewal; when stem cells divide they give rise to stem cells (by
self-renewal) and progenitors (by differentiation). In most tissues only the
primitive stem cells self-renew. Stem cell isolation and transplantation is
the basis for regenerative medicine. Self-renewal is dangerous, and therefore
strictly regulated. Poorly regulated self-renewal can lead to the genesis of
cancer stem cells, the only self-renewing cells in the cancerous tumor.
Known as a renowned medical researcher, an entrepreneur, and an avid fisherman, Irving L. Weissman is Director of the Stanford Institute for Stem Cell Biology and Regenerative Medicine, Director of the Stanford Cancer Center and Director of the Stanford Ludwig Center for Stem Cell Research. A Professor of Pathology and Developmental Biology and, by courtesy, of Biological Sciences and Neurosurgery at Stanford University Medical School, Weissmans research encompasses the biology and evolution of stem cells and progenitor cells, mainly blood-forming and brain-forming. He is also engaged in isolating and characterizing the rare cancer and leukemia stem cells as the only dangerous cells in these malignancies, especially with human cancers. And he has a long-term research interest in the phylogeny and developmental biology of cells that make up the blood-forming and immune systems. Weissmans laboratory was first to identify and isolate the blood-forming stem cell from mice, and has purified each progenitor in the stages of development between the stem cells and mature progeny (granulocytes, macrophages, etc.).
As a pioneer in the field of adult stem cell biology, Weissman co-founded three stem cell companies: SyStemix in 1988, StemCells in 1996, and Celtrans (now Cellerant), the successor to SyStemix in 2001. At SyStemix he co-discovered the human hematopoietic stem cell and at StemCells, he co-discovered a human central nervous system stem cell. In addition, the Weissman laboratory has pioneered the study of the genes and proteins involved in cell adhesion events required for lymphocyte homing to lymphoid organs in vivo, either as a normal function or as events involved in malignant leukemic metastases.
Irving L. Weissmans research encompasses the phylogeny and developmental biology of the cells that make up the blood-forming and immune systems. His laboratory identified and isolated the blood-forming stem cell from mice, and has defined, by lineage analysis, the stages of development between the stem cells and mature progeny (granulocytes, macrophages, etc.). This required developing and cloning stromal cells of the hematolymphoid microenvironments？？？from the bone marrow for myeloid and B cells, and from the thymus for T cells. While the adhesion molecules and factors from these stromal cells proved important as molecules (and the genes that encode them) for myeloid and B cells, the analysis of T cell development required in vivo studies of thymic development. In addition, the Weissman laboratory has pioneered the study of the genes and proteins involved in cell adhesion events required for lymphocyte homing to lymphoid organs in vivo, either as a normal function or as events involved in malignant leukemic metastases.
The Weissman laboratory also has a small group at Hopkins Marine Station, where they have developed a model organism for laboratory and field study of allorecognition？？？the invertebrate counterpart of transplantation immunity. Working with the protochordate Botryllus schlosseri (which has a chordate larval stage and an invertebrate adult form) they have identified a single major gene locus that governs rapid allorecognition, and 2-3 other loci involved in delayed allorecognition events. They are using this model to study the genes, proteins, and cells that govern protochordate allorecognition, and the effects of these genes on their population dynamics in the field.
For more information, visit
http://med.stanford.edu/profiles/Irving_Weissman
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Normal and Neoplastic Stem Cells
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- Evaluating and Understanding Care
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- - Mary Sweeney (2010/11/18)
- - Category : Work/Life Center
- NIH Work Life Seminar
Sometimes the needs of a family member are more comprehensive than what the family or caregiver can provide. In-Home Care may be an answer. But if it is not, the caregiver must make decisions about the future living arrangements, which may include assisted living or a nursing home. In this seminar, you will learn about the different types of nursing homes, how to determine if a nursing home is right for your family and other issues you need to consider in evaluating a nursing home.
For more information, visit
http://wlc.od.nih.gov
Evaluating and Understanding Care
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- National Cancer Advisory Board - June 2008 (Day 2)
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- - United States. National Cancer Advisory Board. Meeting (2010/11/18)
- - Category : National Cancer Advisory Board
- This is a regularly scheduled meeting of the National Cancer Advisory Board (NCAB).
National Cancer Advisory Board - June 2008 (Day 2)