전체 8345
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- Lunch and Learn: Life With Your New Baby
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- - Hazel Osborn (2010/11/18)
- - Category : Parenting
- New parents experience many changes in their lifestyles and relationships when bringing a new baby home. The goal of this seminar is to increase knowledge of what to expect of life with a new baby, from baby care to communication with your spouse to the transition back to work.
Handout available for download at http://videocast.nih.gov/pdf/parenting102908.pdf.
Lunch and Learn: Life With Your New Baby
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- Farewell Celebration for Elias A. Zerhouni, M.D., Director, National Institutes of Health (NIH Only)
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- - National Institutes of Health (U.S.) (2010/11/18)
- - Category : NIH Only
- Dr. Zerhouni？？？s Farewell Celebration
Farewell Celebration for Elias A. Zerhouni, M.D., Director, National Institutes of Health (NIH Only)
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- Sugar Cravings or Sugar Blues
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- - Sponsored by Life Work Strategies (2010/11/18)
- - Category : Work/Life Center
- NIH Work Life Seminar
Do you experience sugar cravings or find yourself lethargic after eating sugary snacks? You may not realize that sugar is a key ingredient in many foods and beverages we consume. In culinary terms, the foodstuff known as sugar delivers a primary taste sensation of sweetness. On the package list of ingredients, any word that ends with OSE...is likely to denote sugar. Added sugar provides calories but no additional nutrients. It can offer a temporary boost of energy, but it will be fleeting.
Sugar can actually have a significant affect on your energy level as well as your waistline. Studies show people who consume foods and drinks with added sugar tend to consume more calories. As well, there is a direct link between weight gain and drinking sweetened beverages. Excess sugar can also pose significant health risks including tooth decay, diabetes, and obesity.
Come to this tempting WLC seminar just in time for Halloween...the Candy Holiday...to learn about the 8 causes of cravings and the 10 steps for dealing with sugar cravings. Participants will receive a recipe packet. Whats more, learn the difference between natural and artificial sweeteners, and how much added sugar to consume daily.
For more information, visit
http://wlc.od.nih.gov
Sugar Cravings or Sugar Blues
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- Emerging Fluorescence Technology for the Analysis of Protein Localization and Organelle Dynamics
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- - Lippincott-Schwartz, Jennifer.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Anita B. Roberts
- - Lippincott-Schwartz, Jennifer.
- The Anita B. Roberts Lecture Series
This series highlights outstanding research achievements of women scientists at the NIH. The seminar is dedicated to Dr. Anita Roberts and honors her role as an exceptional mentor and scientist.
Anita joined the NIH in 1976 and spent 30 years at NCI, rising to Chief of the Laboratory of Cell Regulation and Carcinogenesis. She died of gastric cancer in May 2006, leaving a legacy that touched both the professional and personal lives of all who knew her. Her work focused primarily on TGF-beta and its role in the growth of epithelial and lymphoid cells. In 2003, Thomas Scientifics Science Watch listed her among the 50 most-cited scientists during 1982 to 2002, a feature called Twenty Years of Citation Superstars.
Anita was a superstar to many for her mentoring talent and her ability to balance family and work life. Her successful lab was well known for meeting family needs and for providing an environment both intellectually and emotionally enriching. The lecture series in her name serves to highlight the fact that the NIH recognizes the value and necessity of a supportive workplace.
For more information, visit
http://www1.od.nih.gov/oir/sourcebook/comm-adv/wsa.htm
Emerging Fluorescence Technology for the Analysis of Protein Localization and Organelle Dynamics
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- NIH Directors Council of Public Representatives - October 2008
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- - National Institutes of Health (U.S.). Directors Council of Public Representatives. (2010/11/18)
- - Category : NIH Directors Council of Public Representatives
- The Directors Council of Public Representatives (COPR) is a federal advisory committee made up of members of the public, who advise the National Institutes of Health (NIH) Director on issues related to public participation in NIH activities, outreach efforts, and other matters of public interest.
For more information, visit
http://copr.nih.gov
NIH Directors Council of Public Representatives - October 2008
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- Extending the Hippocampal Memory System: Beyond the Fornix
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- - Aggleton, John P.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Neuroscience
- - Aggleton, John P.
- Professor Aggleton？？？s laboratory examines the neural substrates of learning and memory, with an emphasis on the ways in which different brain regions work in concert to support episodic memory and recognition memory. His research integrates findings from animal and clinical research, and spans multiple levels of analysis, including neuropsychological, physiological, neuroanatomical and molecular approaches. Of particular interest is the interaction among temporal lobe, diencephalic and prefrontal cortex circuits in memory, and understanding the basis of diencephalic amnesia.
NIH Neuroscience Seminar Series
Extending the Hippocampal Memory System: Beyond the Fornix
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- Epicardium as a novel source of cardiac progenitor cells
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- - Pu, William.
National Institutes of Health (U.S.). Stem Cell Interest Group. (2010/11/18) - - Category : Stem Cell
- - Pu, William.
- The Stem Cell Interest Group was established to enhance communication and to foster collaboration among scientists from varying disciplines interested in stem cells. Topics of interest include fundamental stem cell biology, ontogeny, gerontology, and the therapeutic potential of stem cells. The SCIG serves as an open forum for discussion and dissemination of knowledge about all aspects of stem cell biology
For more information, visit
http://tango01.cit.nih.gov/sig/home.taf?_function=main&SIGInfo_SIGID=115
Epicardium as a novel source of cardiac progenitor cells
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- TRACO: Lung Cancer and Radiation Biology
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- - Szabo, E.
National Institutes of Health (U.S.) (2010/11/18) - - Category : TRACO
- - Szabo, E.
- For more information, visit
http://ccr.cancer.gov/careers/traco.asp
TRACO: Lung Cancer and Radiation Biology
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- Redox Biology - Carcinogenesis and Immunology
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- - Yeh, Grace Chao.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Redox Biology
- - Yeh, Grace Chao.
- Redox Biology (RB)
The course is designed for NIH fellows to enhance their knowledge of redox biology. Reactive species such as superoxide, hydrogen peroxide and nitric oxide are associated with cellular toxicity, however, nitric oxide is useful in the treatment cardiovascular disease. The course will examine the role of reactive nitrogen and oxygen species in carcinogenesis, cancer proliferation and angiogenesis.
For more information, visit
http://ccr.cancer.gov/careers/courses/rb
Redox Biology - Carcinogenesis and Immunology
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- How the Genome and the Computer Have Changed Our View of Cancer(NIH-Only)
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- - Botstein, David.
National Institutes of Health (U.S.) (2010/11/18) - - Category : NCI CCR Grand Rounds (NIH Only)
- - Botstein, David.
- NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link:
http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx
How the Genome and the Computer Have Changed Our View of Cancer(NIH-Only)
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- NCI Awards Ceremony (NIH Only)
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- - National Cancer Institute (2010/11/18)
- - Category : NIH Only
- 내용 없음
NCI Awards Ceremony (NIH Only)
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- I Thought Neuroanatomy was Difficult - Development of New Computer-Based Methods for Learning Anatomy of the Brain
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- - Pani, John R.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Special
- - Pani, John R.
- NLM Informatics Lecture Series
New, interactive, computer-based methods of learning can streamline education in biomedicine and make basic neuroanatomy accessible to everyone. This talk presents my work on: - a 3D computer graphical model of the human brain based on the Visible Human - development of several programs that enhance learning neuroanatomy for both 3D whole structures and sectional views.
Neuroanatomy has a long-held reputation as a difficult discipline to master. Such a challenging process of learning appears to be characteristic of anatomical disciplines in which the primary method for viewing structures is through sectional imagery (e.g., microscope slides and MRI images).
My work is premised on the belief that new interactive computer-based methods can make learning neuroanatomy far more efficient. These methods can streamline education in biomedicine and make basic neuroanatomy accessible to everyone.
In this talk, I report work that included:
1) construction of a new 3D computer graphical model of the human brain based on the Visible Human (Vers. 2.0)
2) development of several interactive computer graphical programs that permitted students to learn neuroanatomy both for 3D whole structures and sectional views
3) empirical measurement and experimental comparison of learning for 72 participants who began the study with no knowledge of neuroanatomy
4) tests of delayed retention of knowledge and generalization to interpretation of biomedical images (Visible Human and MRI)
Consistent with initial hypotheses, learning the brain as whole 3D structures was substantially faster than learning it in sectional views. There was good transfer of knowledge from whole brain learning to sectional learning. Generalization of learning to biomedical images was overall quite good, although it depended on the quality of the images (with Visible Human images being substantially easier than MRI images) and the specific nature of the test.
I Thought Neuroanatomy was Difficult - Development of New Computer-Based Methods for Learning Anatomy of the Brain
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- TDP-43: A New Class of Proteinopathies in Neurodegerative Diseases
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- - Lee, V M-Y.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Wednesday Afternoon Lectures
- - Lee, V M-Y.
- Over the past decade it has become clear that there is significant overlap in the clinical phenotypes of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). The identification of TDP-43 as the major disease protein in the neuropathology of both FTLD with ubiquitin inclusions (FTLD-U) and ALS provides the first molecular link for these diseases and suggest that they belong to the same clinicopathological spectrum of disorder.
Pathological TDP-43 is abnormally phosphorylated, ubiquitinated, and cleaved to generate carboxy-terminal fragments in affected brain regions. The normal nuclear expression of TDP-43 is also reduced leading to the hypothesis that sequestration of TDP-43 in pathological inclusions contributes to disease pathogenesis. Thus, TDP-43 is the newest member of the growing list of neurodegenerative proteinopathies, but unique in that it lacks features of brain amyloidosis. Autosomal dominantly inherited TDP-43 mutations were also identified in familial ALS patients thereby suggesting a paradigm shift in our understanding on the etiology and pathogenesis of ALS. This presentation will provide an up-to-date summary of this very fast moving area of research.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
TDP-43: A New Class of Proteinopathies in Neurodegerative Diseases
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- Innate Activation of Dendritic Cells
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- - Sousa, Caetano Reis e.
National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18) - - Category : Immunology
- - Sousa, Caetano Reis e.
- Next week？？？s IIG seminar will be presented by Dr. Caetano Reis e Sousa of Cancer Research UK (formerly the ICRF). Caetano is an ex-NIHer, having done his post-doctoral training in the Laboratory of Immunology, NIAID with Ron Germain. His long-standing interest has been in dendritic cells and innate sensing and he and his laboratory group have had a spectacular run over the past few years in these areas. While still at NIH, Caetano worked with Alan Sher to demonstrate that microbial signals, in this case in the form of a Toxoplasma extract, evoked IL-12 responses from DCs that also changed their tissue distribution when stimulated by this material. He also provided some of the earliest data showing that MHC class II-dependent antigen processing and presentation by DCs was controlled by TLR signaling. With his own group, Caetano has been a leader in uncovering novel pathways involved in microbial sensing and the contributions of such signals to the development of adaptive immune responses. His seminal contributions include describing the role of PKR in viral induction of interferon responses, the role of Tlr7 in innate responses to single stranded RNA, the distinctions between indirect cytokine and direct TLR stimulation in DC promotion of effector T cells responses, the role of Tlr3 in promoting cross-presentation by DCs, the novel linkage of C-type lectin receptors to the Syk signaling pathway along with the role of dectin-1 and this Syk pathway in driving Th17 responses in response to yeast, and the recognition of 5？？？ phosphorylated RNA by the intracellular sensor RIGI, among may others. More recently, he has identified additional C-type lectins involved in DAMP sensing, linking his previous studies on microbial stimuli to mechanisms involved in responding to tissue damage. Caetano is not only a superb scientist, he is an outstanding communicator and his seminar is certain to be insightful, information, and intellectually exciting. Don？？？t miss this one.
For more information, visit
The Immunology Interest Group
Innate Activation of Dendritic Cells
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- Ethical Issues in International Research - 2008 (Session 7)
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- - Shah, Seema.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Bioethics
- - Shah, Seema.
- Ethical and Regulatory Aspects of Clinical Research
Department of Clinical Bioethics
This course is designed to provide a historical context for research regulations and to help researchers and others working in human subject research gain insights and skills into the development of research protocols and their ethical implementation.
Objectives of the Course:
To learn the codes, declarations, and other documents that govern the ethical conduct of human subject research; review the critical elements of informed consent and their implementation in actual informed consent documents for clinical research; explore controversial issues relating to human subject research, including Phase I research, randomization, children in research, international research, etc; review the purpose if IRBs and provide IRB-like experience in reviewing research protocols; understand the experience of human subjects who have participated in research protocols.
For more information, visit
http://www.bioethics.nih.gov
Ethical Issues in International Research - 2008 (Session 7)
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- NCI Board of Scientific Advisors - November 2008 (Day 1)
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- - NCI Board of Scientific Advisors. Meeting (2010/11/18)
- - Category : NCI Board of Scientific Advisors
Provides scientific advice on a wide variety of matters concerning scientific program policy, progress, and future direction of the NCIs extramural research programs, and concept review of extramural program initiatives.
For more information, visit
http://deainfo.nci.nih.gov/advisory/bsa.htm
NCI Board of Scientific Advisors - November 2008 (Day 1)
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- Uncovering Protein Complexes and Assemblies: Stories of Dynamic Virus-Host Interactions and Specific Synapse Characterization
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- - Cristea, Ileana M.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Proteomics
- - Cristea, Ileana M.
- Isolation of protein complexes, if performed appropriately, can provide an invaluable shortcut to uncovering protein interactions and to gaining clues towards their biological functions. The literature is, justifiably so, replete with approaches designed for the study of protein interactions. Advances are, nevertheless, highly desirable. An ideal isolation would maintain the protein complex or a larger assembly of interest as close as possible to its original state in the cell. To date, achieving this ideal isolation remains a challenge. The identification of transient or weak interacting partners and the stoichiometry within a complex present difficulties. We have recently reported an approach for the rapid and efficient isolation of protein complexes. We demonstrated that a combination of cryogenic-based cell lysis and fast immunoaffinity purifications helps to maintain interactions, minimizing nonspecific associations and maximizing the recovery of transiently interacting partners. This presentation will underline some of the technical aspects that were found to be important in studying protein complexes, as well as macromolecular assemblies. Highlights will be shown from our studies of the dynamic viral-host protein interactions during the course of infections with Sindbis and human cytomegalovirus HCMV. Our results revealed cellular pathways utilized by these viruses to manipulate host systems.
http://proteome.nih.gov
In case of problems with this stream, there is a backup stream at http://videocast.nih.gov/ram/protig110708.ram
Uncovering Protein Complexes and Assemblies: Stories of Dynamic Virus-Host Interactions and Specific Synapse Characterization
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- Synthetic Scaffolds to Target Biological Macromolecules
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- - Appella, Daniel.
National Institutes of Health (U.S.) (2010/11/18) - - Category : NIH Directors Seminars
- - Appella, Daniel.
- 2008-2009 Directors Seminar Series
For more information, visit
http://www.nih.gov/about/director/dirsem.htm
Synthetic Scaffolds to Target Biological Macromolecules
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- NCI Board of Scientific Advisors - November 2008 (Day 2)
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- - NCI Board of Scientific Advisors. Meeting (2010/11/18)
- - Category : NCI Board of Scientific Advisors
Provides scientific advice on a wide variety of matters concerning scientific program policy, progress, and future direction of the NCIs extramural research programs, and concept review of extramural program initiatives.
For more information, visit
http://deainfo.nci.nih.gov/advisory/bsa.htm
NCI Board of Scientific Advisors - November 2008 (Day 2)
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- Transforming Science: Cancer Control on caBIG
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- - National Cancer Institute (U.S.). Division of Cancer Control and Population Sciences. (2010/11/18)
- - Category : Special
- The DCCPS fall forum on cyberinfrastructure is a collaborative event, co-sponsored by HCIRB, OCE, and CBIIT which will use demonstrations of innovative, grid-enabled projects to explore the advantages of cyber-enabled research in cancer prevention and control. The event will demonstrate how cyberinfrastructure has the potential to support a new, transformative science in behavioral medicine and population health.
For more information, visit http://guest.cvent.com/i.aspx?5S,M3,5af10dd6-ecaa-41d6-83de-7bce341532bb
Transforming Science: Cancer Control on caBIG