전체 8345
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- TRACO: HIV and Metastasis
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- - Maldarelli, F.
National Institutes of Health (U.S.) (2010/11/18) - - Category : TRACO
- - Maldarelli, F.
- For more information, visit
http://ccr.cancer.gov/careers/traco.asp
TRACO: HIV and Metastasis
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- NIAID HIV AIDS Strategic Working Group Meeting - Day 1 (NIH Only)
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- - National Institute of Allergy and Infectious Diseases (U.S.). HIV AIDS Strategic Working Group. (2010/11/18)
- - Category : NIAID Council (NIH Only)
- 내용 없음
NIAID HIV AIDS Strategic Working Group Meeting - Day 1 (NIH Only)
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- Mammalian Gene Collection (MGC) Symposium
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- - Mammalian Gene Collection Symposium (2010/11/18)
- - Category : Conferences
- In this final year of the Mammalian Gene Collection, the speakers at the MGC symposium will highlight significant biomedical studies and advances in their laboratories that have been aided by the unrestricted access of the scientific community to the MGCs high-quality full-CDS cDNA clones and sequences.
For more information, click here: http://web.ncifcrf.gov/events/mge/default.asp
Mammalian Gene Collection (MGC) Symposium
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- Translational Trials and Tribulations (NIH-Only)
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- - Kohn, Elise C.
National Institutes of Health (U.S.) (2010/11/18) - - Category : NCI CCR Grand Rounds (NIH Only)
- - Kohn, Elise C.
- Dr. Kohn is a graduate of the University of Michigan Medical School where she also completed residency training in internal medicine; she came to NCI for medical oncology training in the Medicine Branch.
Dr. Kohn then joined the Laboratory of Pathology to investigate signal transduction molecular targets in invasion, angiogenesis, and ovarian cancer, and maintained her clinical focus in the translational clinical studies of ovarian cancer. Her clinical work has evolved to apply new proteomic technologies to early detection testing and validation of therapeutic targets in clinical trials. Dr. Kohn has been investigating targeting molecular events of the local tumor microenvironment. Dr. Kohn serves on numerous NIH and NCI committees, and is the newly elected chair of the Integration Panel of the Department of Defense Ovarian Cancer Research Program. Dr. Kohn is a participating member and protocol investigator in the Gynecologic Oncology Group, is a judge of the yearly Fellows Award for Research Excellence competition, and is the co-chair of the CCR Breast and Gynecologic Malignancies Faculty. She was recognized with the NCI Diversity Award and Mentor of Merit Award in 2007. Dr. Kohn was elected as a Fellow of the American Association for the Advancement of Science.
NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link:
http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx
Translational Trials and Tribulations (NIH-Only)
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- NIAID HIV AIDS Strategic Working Group Meeting - Day 2 (NIH Only)
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- - National Institute of Allergy and Infectious Diseases (U.S.). HIV AIDS Strategic Working Group. (2010/11/18)
- - Category : NIAID Council (NIH Only)
- 내용 없음
NIAID HIV AIDS Strategic Working Group Meeting - Day 2 (NIH Only)
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- American Health Information Community - September 2008
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- - American Health Information Community. Meeting (2010/11/18)
- - Category : American Health Information Community
- The American Health Information Community (the Community), is a committee established under the Federal Advisory Committee Act (Pub. L. No. 92-463, 5 U.S.C., App.), by the Secretary of the Department of Health and Human Services. The Community will advise the Secretary and recommend specific actions to achieve a common interoperability framework for health information technology (IT) and serve as a forum for participation from a broad range of stakeholders to provide input on achieving interoperability of health IT. The Community is made up of 17 voting members, including the Chair, and members have been appointed by the Secretary.
The Web address for the Communitys draft charter is:
http://www.hhs.gov/healthit/ahiccharter.pdf
A complete list of members can be found at:
http://www.hhs.gov/healthit/ahic.html
American Health Information Community - September 2008
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- Fourth Annual NIH Directors Pioneer Award Symposium (Day 2)
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- - NIH Directors Pioneer Awards Symposium (2010/11/18)
- - Category : Conferences
- The event features a keynote address by NIH Director Dr. Elias Zerhouni, talks by scientists who received Pioneer Awards in 2007, poster sessions by Pioneer and New Innovator Award recipients, roundtable discussions, and ample opportunities for informal interaction. At the start of the symposium, Zerhouni will announce the 2008 recipients of NIH Director？？？s Pioneer and New Innovator awards. Both programs support exceptionally creative scientists who take highly innovative, and often unconventional, approaches to major challenges in biomedical or behavioral research.
http://nihroadmap.nih.gov/pioneer/Symposium2008/index.aspx
Fourth Annual NIH Directors Pioneer Award Symposium (Day 2)
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- Viral Forecasting
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- - Wolfe, Nathan.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Wednesday Afternoon Lectures
- - Wolfe, Nathan.
- The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
For more information, visit http://gvfi.org/index.html
Viral Forecasting
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- 10 Strategies for Healthy Living
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- - Susan Mudd, sponsored by Life Work Strategies (2010/11/18)
- - Category : Work/Life Center
- NIH Work Life Seminar
This seminar has been designed to teach you about some behaviors that, when practiced, can improve your personal wellness. Our health is a result of our behavior-how we treat ourselves throughout the course of our lives. Attend this seminar to get yourself motiviated or ready to make a positive change in your diet or exercise habits.
For more information, visit
http://wlc.od.nih.gov
10 Strategies for Healthy Living
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- Postbac Seminar Series - Giving a Science Talk
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- - Ruiz Bravo, Norka.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Career Development/OITE
- - Ruiz Bravo, Norka.
- Learn the techniques for giving a great scientific presentation.
Postbac Seminar Series - Giving a Science Talk
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- Structural Insights into Recognition and Signaling by T Cell and Cytokine Receptors
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- - Garcia, K Christopher.
National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18) - - Category : Immunology
- - Garcia, K Christopher.
- For more information, visit
The Immunology Interest Group
Structural Insights into Recognition and Signaling by T Cell and Cytokine Receptors
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- History, Guidance, and Framework for Ethical Clinical Research - 2008 (Session 1)
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- - Emanuel, Ezekiel J.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Bioethics
- - Emanuel, Ezekiel J.
- Ethical and Regulatory Aspects of Clinical Research
Department of Clinical Bioethics
This course is designed to provide a historical context for research regulations and to help researchers and others working in human subject research gain insights and skills into the development of research protocols and their ethical implementation.
Objectives of the Course:
To learn the codes, declarations, and other documents that govern the ethical conduct of human subject research; review the critical elements of informed consent and their implementation in actual informed consent documents for clinical research; explore controversial issues relating to human subject research, including Phase I research, randomization, children in research, international research, etc; review the purpose if IRBs and provide IRB-like experience in reviewing research protocols; understand the experience of human subjects who have participated in research protocols.
For more information, visit
http://www.bioethics.nih.gov
History, Guidance, and Framework for Ethical Clinical Research - 2008 (Session 1)
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- Quantitative and Systems Pharmacology (QSP) Workshop (Day 1)
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- - National Institute of General Medical Sciences (U.S.) (2010/11/18)
- - Category : Conferences
- The Quantitative and Systems Pharmacology (QSP) Workshop will provide state-of-the-art knowledge and perspective about topics at the interface of systems biology and pharmacology to a highly diverse spectrum of researchers in academia, industry, and government. The question of where systems biology, modeling, and more quantitative measurements can be applied to pharmacology and drug discovery/action now and in the near future will be addressed. Accordingly, the talks will emphasize both conceptual information and significant research findings concerning the topic. The topic will be approached from the standpoint of both a horizontal integration (various networks in various cell systems) and a vertical integration (connections between pathways at different levels of integration, tissues, organs, etc.). Consideration of the current knowledge as well as future research needs in various areas will be made. The workshop will feature discussion sessions based on the presentations, throughout the two-day period. The meeting goals include highlighting where the state-of-the-art resides in relevant disciplines today, fostering integration of research efforts in these areas with others, identifying barriers (problems merging two disciplines), increasing collaboration between pharmacologists, clinicians, and systems biologists, and establishing pressing and long-term research needs (training, instrumentation, algorithms, etc.) for advancement of the ability of systems biology to inform drug discovery and drug action.
Conference agena avialable at http://videocast.nih.gov/pdf/QSP_agenda.pdf
For more information, visit http://meetings.nigms.nih.gov/meetings/QSPcolWorkshop/.
Quantitative and Systems Pharmacology (QSP) Workshop (Day 1)
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- NIH Extramural Staff Training on the Animal Events Response Toolkit (HHS Only)
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- - Ruiz Bravo, Norka.
National Institutes of Health (U.S.) (2010/11/18) - - Category : ESA (HHS Only)
- - Ruiz Bravo, Norka.
- The NIH values the safety, security, and well-being of the researchers, animals, and institutions it funds. NIH-funded projects that use animal models are sometimes threatened or attacked by animal rights extremists. This training opportunity reviews a newly created set of resources and processes to help to the staff of the NIH Extramural Program give guidance aimed at preparing for and responding to threats and incidents against NIH-funded projects.
For more information, visit
http://odoerdb2-1.od.nih.gov/oer/training
NIH Extramural Staff Training on the Animal Events Response Toolkit (HHS Only)
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- Quantitative and Systems Pharmacology (QSP) Workshop (Day 2)
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- - National Institute of General Medical Sciences (U.S.) (2010/11/18)
- - Category : Conferences
- The Quantitative and Systems Pharmacology (QSP) Workshop will provide state-of-the-art knowledge and perspective about topics at the interface of systems biology and pharmacology to a highly diverse spectrum of researchers in academia, industry, and government. The question of where systems biology, modeling, and more quantitative measurements can be applied to pharmacology and drug discovery/action now and in the near future will be addressed. Accordingly, the talks will emphasize both conceptual information and significant research findings concerning the topic. The topic will be approached from the standpoint of both a horizontal integration (various networks in various cell systems) and a vertical integration (connections between pathways at different levels of integration, tissues, organs, etc.). Consideration of the current knowledge as well as future research needs in various areas will be made. The workshop will feature discussion sessions based on the presentations, throughout the two-day period. The meeting goals include highlighting where the state-of-the-art resides in relevant disciplines today, fostering integration of research efforts in these areas with others, identifying barriers (problems merging two disciplines), increasing collaboration between pharmacologists, clinicians, and systems biologists, and establishing pressing and long-term research needs (training, instrumentation, algorithms, etc.) for advancement of the ability of systems biology to inform drug discovery and drug action.
Conference agena avialable at http://videocast.nih.gov/pdf/QSP_agenda.pdf
For more information, visit http://meetings.nigms.nih.gov/meetings/QSPcolWorkshop/.
Quantitative and Systems Pharmacology (QSP) Workshop (Day 2)
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- Methodological and Conceptual Issues in Conducting Research on Racial/Ethnic Discrimination in Health Care Delivery
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- - National Cancer Institute (U.S.) (2010/11/18)
- - Category : Special
- This workshop is being sponsored by the National Cancer Institute (NCI) in collaboration with the National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute of Diabetes and Digestive and Kidney Diseases, and the National Institute on Drug Abuse. The purpose of the workshop is to stimulate interest, improve methodological approaches, and encourage submission of high-quality research grant applications that examine the role of racial/ethnic discrimination in the receipt of health care and health disparities. The specific objectives of the technical workshop are:
- To examine the current state of and identify gaps in the research related to the role that racial/ethnic discrimination plays in the receipt of health care in the U.S.
- To generate a research agenda that identifies research questions that are high priority, feasible, and relevant to research on the role of racial/ethnic discrimination in health care delivery.
- To improve the technical and grant-writing skills of applicants and thus increase the likelihood of funding success.
- To encourage the development of an interdisciplinary community of scholars interested in and conducting research on this topic.
Methodological and Conceptual Issues in Conducting Research on Racial/Ethnic Discrimination in Health Care Delivery
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- Redox Biology - Introduction and Redox Chemistry
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- - Moody, Terry W.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Redox Biology
- - Moody, Terry W.
- Redox Biology (RB)
The course is designed for NIH fellows to enhance their knowledge of redox biology. Reactive species such as superoxide, hydrogen peroxide and nitric oxide are associated with cellular toxicity, however, nitric oxide is useful in the treatment cardiovascular disease. The course will examine the role of reactive nitrogen and oxygen species in carcinogenesis, cancer proliferation and angiogenesis.
For more information, visit
http://ccr.cancer.gov/careers/courses/rb
Redox Biology - Introduction and Redox Chemistry
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- Infectious Disease and Public Health: The Ethics of Intervention
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- - Whittall, Hugh.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Clinical Center Grand Rounds
- - Whittall, Hugh.
- Clinical Center Grand Rounds
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
Infectious Disease and Public Health: The Ethics of Intervention
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- Chaperone-Mediated Autophagy: Tales from an Old "Picky" Broom
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- - Cuervo, Ana Maria.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Wednesday Afternoon Lectures
- - Cuervo, Ana Maria.
- Cells count on surveillance systems to handle protein alterations. Malfunctioning of these systems contribute in large extend to the abnormal accumulation of those altered proteins in cells and tissues in numerous diseases and in aging. Our studies have focused primarily in one of the cellular systems for protein removal, chaperone-mediated autophagy (CMA), which mediates selective targeting of cytosolic proteins to lysosomes for their degradation.
CMA is active in most mammalian cell types but its activity varies depending on cellular conditions. Maximal activation of CMA is attained during stresses such as nutritional stress, mild-oxidative stress or toxin exposure. Degradation by CMA requires the presence of a targeting motif in the substrate protein, a set of cytosolic and lysosomal chaperones and a receptor protein at the lysosomal membrane. Blockage of CMA in culture cells diminishes their ability to adapt to most types of stresses and promotes formation of protein aggregates. Using this model, we have revealed a cross-talk among different removal systems, since in response to diminished CMA activity cells activate other forms of autophagy that compensate for CMA failure, but renders them susceptible to stress.
CMA activity declines with age and in some age-related pathologies such as Parkinson？？？s disease. We have identified the reason for the decline in CMA function with age as a decrease in the levels of the lysosomal receptor that mediates substrate translocation. Our group is currently developing different approaches aimed to restore normal CMA activity in old rodents. These models would help us evaluate the importance of maintaining proper protein removal until advanced ages, and, on light of the observed cross-talk among autophagic pathways, the effect that repairing one autophagic pathway may have on the functioning of the others.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
For more information, visit http://www.aecom.yu.edu/cuervo/
Chaperone-Mediated Autophagy: Tales from an Old "Picky" Broom
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- Stars in Nutrition and Cancer: A Family Based Approach to Breast Cancer Prevention
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- - Olufunmilayo Olopade, M.D. (2010/11/18)
- - Category : Stars in Nutrition
- NCI Stars in Nutrition Lecture Series
Meeting Objectives:- To understand familial aspects of breast cancer;
- To understand the contribution of high risk alleles and low penetrant genes;
- To emphasize primary prevention strategies for familial breast cancer; and
- To explore interventions for breast cancer prevention, including lifestyle and nutritional approaches.
This lecture series features extraordinary contributors or stars in the field of cancer and nutrition research. Speakers highlight the important role that nutrition plays in modifying cancer development. The lectures aim to facilitate interdisciplinary interactions among basic scientists, clinicians, and behavioral and social scientists. Lectures typically occur each fall and spring.
For more information, visit
http://prevention.cancer.gov
Stars in Nutrition and Cancer: A Family Based Approach to Breast Cancer Prevention