전체 8345
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- From Peppers to Peppermints: Natural Products as Probes of the Pain Pathway
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- - David Julius, Ph.D. (2010/11/18)
- - Category : Neuroscience
From Peppers to Peppermints: Natural Products as Probes of the Pain Pathway
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- Advances in Rational Vaccine Design: Relevance to Infectious Diseases and Cancer (NIH-Only)
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- - Gary J. Nabel, M.D., Ph.D. (2010/11/18)
- - Category : NCI CCR Grand Rounds (NIH Only)
- Dr. Nabel provides overall direction and scientific leadership of the basic, clinical, and translational research activities of the VRC, and guides development of novel vaccine strategies against HIV and other emerging and re-emerging infectious diseases, including Ebola/Marburg hemorrhagic fevers, influenza, and other viruses. The efforts of the Center are directed towards several major areas of vaccine research and development including the definition of immune mechanisms that may protect against HIV infection; the influence of cellular and humoral immune responses on protection; the conception, design, and preparation of vaccine candidates for HIV and other infectious diseases; and the initiation of multiple human clinical trials to test the safety and immune response of these vaccine candidates. Under Dr. Nabel？？？s leadership, the VRC was able to initiate its first clinical trial, a Phase I study of an HIV/AIDS vaccine within a year after opening, and has developed an HIV candidate vaccine that is presently in a Phase II efficacy trial. Dr. Nabel also serves as Chief of the Virology Laboratory at the VRC which examines molecular regulation of HIV replication, optimization of immune responses to gene-based vaccination, and development of improved HIV envelope immunogens.
Dr. Nabel graduated magna cum laude from Harvard College in 1975 and continued his graduate studies at Harvard, completing his Ph.D. in 1980 and his M.D. two years later. He then served as a postdoctoral fellow in the laboratory of David Baltimore at MIT？？？s Whitehead Institute. Before his appointment at the VRC, Dr. Nabel served as the Henry Sewall Professor of Internal Medicine, professor of Biochemistry, and Howard Hughes Medical Institute investigator at the University of Michigan in Ann Arbor. In addition to his faculty positions, Dr. Nabel also served as the Director of the Center for Gene Therapy and co-director of the Center for Molecular Medicine at the University of Michigan.
Dr. Nabel has also established a distinguished track record in developing novel therapeutic approaches. For example, Dr. Nabel and his colleagues were the first to use direct gene transfer to introduce therapeutic proteins into patients with melanoma, showing the feasibility and safety of this approach. In recognition of his expertise at the forefront of virology, immunology, gene therapy, and molecular biology, Dr. Nabel was elected as a member of the Institute of Medicine of the National Academy of Sciences in 1998, where he still serves. Among his many other honors, Dr. Nabel has received the Amgen Scientific Achievement Award from the American Society for Biochemistry and Molecular Biology, the Health and Human Services Secretary？？？s Award for Distinguished Service in 2003, and election to the American Association of Physicians, the American Association for Advancement of Science, and the American Society of Microbiology. Dr. Nabel has been chosen as the Keynote Speaker and Distinguished Lecturer at numerous scientific meetings, including the Jenner Lecture at St. George？？？s Hospital London and the 2007 Distinguished Lecturer of Virology at Oxford University. He is the author of over 350 scientific publications.
NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link: http://bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx.
Advances in Rational Vaccine Design: Relevance to Infectious Diseases and Cancer (NIH-Only)
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- SEER-Medicare Data Training Workshop - March 2010 (Day 2)
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- - Dr. Joan Warren, National Cancer Institute (2010/11/18)
- - Category : Conferences
- The purpose of the training is to assist investigators who are new to the SEER-Medicare data in understanding some of the methodological issues associated with using these data for epidemiologic and health services research.
http://conference.novaresearch.com/SEER/
SEER-Medicare Data Training Workshop - March 2010 (Day 2)
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- Administrative Strategies - My Space and Facebook and Twitter, Oh My! The Potential of Social Networking Tools for Public Health Research (HHS Only)
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- - NIH (2010/11/18)
- - Category : STEP (HHS Only)
- STEP: Staff Training in Extramural Programs
It is challenging to keep up with the lingo and the technology provided by the Internet. Experts talk about the immense opportunity for commerce and knowledge transfer -- how can scientists get in on the action? This forum will present the latest Internet-based social networking developments and how researchers can use these technologies to expedite interdisciplinary communication, expand knowledge, and reach a potentially untapped population. Come tweet with us!
Committee Members:- Chair: Marina Broitman
- Martha Hare
- Susan Haynes
- Bob Mays
- Richard Okita
- Yasaman Shirazi
- Kate White
http://odoerdb2-1.od.nih.gov/oer/training/step/step_training_20100309.htm
Administrative Strategies - My Space and Facebook and Twitter, Oh My! The Potential of Social Networking Tools for Public Health Research (HHS Only)
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- NIH Consensus Development Conference on Vaginal Birth After Cesarean: New Insights - Day 2
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- - Sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development Office of Medical Applications of Research of the National Institutes of Health (2010/11/18)
- - Category : Conferences
- For most of the 20th century, clinicians believed that once a woman had undergone a cesarean, all of her future pregnancies required delivery by that procedure as well. In the 1980s, vaginal birth after cesarean (VBAC) also began to be considered a viable option for these women. Since 1996, however, VBAC rates in the United States have consistently declined, while cesarean delivery rates have been steadily rising. What accounts for these changing practice patterns? Frequently cited concerns about VBAC include the possibility of uterine rupture during labor, infection, and other complications. However, repeat cesarean delivery carries risks for both mother and baby, and may impact future pregnancies. Be part of a pivotal discussion that will explore these issues.
http://consensus.nih.gov/2010/vbac.htm
NIH Consensus Development Conference on Vaginal Birth After Cesarean: New Insights - Day 2
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- Genome-Wide Association Studies
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- - Karen Mohlke, Ph.D. (2010/11/18)
- - Category : Current Topics in Genome Analysis
- Current Topics in Genome Analysis
http://genome.gov/COURSE2010
Genome-Wide Association Studies
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- Friederichs Ataxia: N Iron Link
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- - Kenneh Fischbeck (NINDS), Tracey Rouault (NICHD) (2010/11/18)
- - Category : Demystifying Medicine
- The course includes presentation of patients, pathology, diagnosis and therapy in the context of major disease problems and current research. Primarily directed toward Ph.D. students, fellows, and staff, it is also of interest to medical students and clinicians. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components which are presented by NIH staff and outside invitees.
For more information, visit
http://www1.od.nih.gov/oir/DemystifyingMed
Friederichs Ataxia: N Iron Link
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- Clinical Trials and Translational Research Advisory Committee
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- - Coordinating Center for Clinical Trials, National Cancer Institute (2010/11/18)
- - Category : Clinical Trials and Translational Research Advisory Committee
- The Committee provides advice to the Director, NCI, NCI Deputy Directors, and the Director of each NCI Division on the NCI-supported national clinical trials and translational research enterprise to build a strong scientific infrastructure by bringing together a broadly developed and engaged coalition of stakeholders involved research on cancer.
For more information, visit
http://deainfo.nci.nih.gov/advisory/ctac/ctac.htm
Clinical Trials and Translational Research Advisory Committee
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- Scientific Management Review Board Meeting - March 2010
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- - NIH (2010/11/18)
- - Category : Scientific Management Review Board
- The Scientific Management Review Board was authorized by the NIH Reform Act of 2006 and signed into law by the President in January 2007. The NIH Reform Act provides certain organizational authorities to HHS and NIH officials regarding NIH institutes and centers and the Office of the Director. The purpose of the Scientific Management Review Board is to advise HHS and NIH officials on the use of those organizational authorities.
This Working Group of the SMRB is convened to recommend to the full Board whether organizational change within NIH could further optimize research into substance use, abuse, and addiction and maximize human health and/or patient well being. In addressing this issue, the SUAA Working Group will consider the scientific opportunities, public health needs, and research technologies in substance use, abuse, and addiction, in addition to research in these areas under the existing NIH structure.
For more information, visit http://smrb.od.nih.gov
Scientific Management Review Board Meeting - March 2010
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- Recombinant DNA Advisory Committee (RAC) March 2010 - Day 1
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- - NIH (2010/11/18)
- - Category : Recombinant DNA Advisory Committee
- The RAC is a technical committee whose goal is to consider the current state of knowledge and technology regarding recombinant DNA. This includes review of human gene transfer trials, and an assessment of the ability of DNA recombinants to survive in nature and the potential for transfer of genetic material to other organisms. It also considers hypothetical hazards and methods for monitoring and minimizing risks. Approximately one-third of the 15 members do not have scientific expertise but represent public interests and attitudes. This balance is intended to provide a forum for open public debate of social and scientific issues attendant to recombinant DNA research. The RAC has been overwhelmingly successful in achieving this goal.
For more information, visit the
Recombinant DNA Advisory Committee (RAC) Conference Web Site
Recombinant DNA Advisory Committee (RAC) March 2010 - Day 1
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- NIH Consensus Development Conference on Vaginal Birth After Cesarean: New Insights - Day 3
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- - Sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development Office of Medical Applications of Research of the National Institutes of Health (2010/11/18)
- - Category : Conferences
- For most of the 20th century, clinicians believed that once a woman had undergone a cesarean, all of her future pregnancies required delivery by that procedure as well. In the 1980s, vaginal birth after cesarean (VBAC) also began to be considered a viable option for these women. Since 1996, however, VBAC rates in the United States have consistently declined, while cesarean delivery rates have been steadily rising. What accounts for these changing practice patterns? Frequently cited concerns about VBAC include the possibility of uterine rupture during labor, infection, and other complications. However, repeat cesarean delivery carries risks for both mother and baby, and may impact future pregnancies. Be part of a pivotal discussion that will explore these issues.
http://consensus.nih.gov/2010/vbac.htm
NIH Consensus Development Conference on Vaginal Birth After Cesarean: New Insights - Day 3
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- The Science of Small Clinical Trials Lecture Series: BONUS Lecture: Case Studies
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- - Office of Rare Diseases Research (NIH) & Office of Orphan Products Development (FDA) (2010/11/18)
- - Category : Science of Small Clinical Trials
- Dr. Donald Berry will describe and basic principles underlying Bayesian clinical trial design and analysis, illustrating his remarks with concrete case studies drawn from his extensive experience.
The Science of Small Clinical Trials Lecture Series: BONUS Lecture: Case Studies
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- Great Teachers: Vitamin D, Cardiovascular Disease, and Cancer: Emerging Evidence
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- - JoAnn E. Manson, MD, DrPH (2010/11/18)
- - Category : Clinical Center Grand Rounds
- Contemporary Clinical Medicine: Great Teachers
JoAnn E. Manson, MD, DrPH,
Chief, Division of Preventive Medicine, and
Co-Director of the Connors Center for Womens Health and Gender Biology, Brigham and Womens Hospital;
Professor of Medicine and the Elizabeth Fay Brigham Professor of Womens Health, Harvard Medical School
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
Great Teachers: Vitamin D, Cardiovascular Disease, and Cancer: Emerging Evidence
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- Optimal Health: Self Esteem, Physical Activity, and Nutrition
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- - JaWanna Henry (2010/11/18)
- - Category : Focus on You Wellness
- Focus on You Wellness Lecture Series
The NIH is committed to promoting and protecting the health of our employees as we work to further the NIH mission of extending healthy life and reducing the burden of disease and disability for people around the world. Wellness lectures will move to various locations each month including on- and off-campus sites.
http://dats.ors.od.nih.gov/
Optimal Health: Self Esteem, Physical Activity, and Nutrition
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- Fourth Sayer Vision Research Lecture (NIH Only)
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- - Tsien, Roger Y.
National Eye Institute. (2010/11/18) - - Category : NIH Only
- - Tsien, Roger Y.
- Nobel Laureate to Give Fourth Annual Sayer Lecture, Hosted by NEI
Roger Y. Tsien, Ph.D., winner of the Nobel Prize in Chemistry for 2008, will deliver the fourth annual Sayer Vision Research Lecture on Wednesday, March 10 at 1 p.m. in Masur Auditorium, Bldg. 10. His talk is titled: ？？？Breeding and Building Molecules to Spy on Cells and Tumors.？？？
Dr. Tsien, an investigator and professor at the Howard Hughes Medical Institute and the University of California, San Diego, was awarded the Nobel Prize for his contribution toward the discovery and development of green fluorescent protein (GFP). His work has developed GFP into a tool used by researchers worldwide to analyze the movements, positions, and interactions of tagged proteins within cells. Recently, fluorescent proteins have been used to visualize synaptic circuits, allowing researchers to map glial territories and follow glial cells and neurons over time in vivo.
Dr. Tsien？？？s research is at the interface of organic chemistry, cell biology, and neurobiology. He is best known for designing and building molecules that either report or perturb signal transduction inside living cells. Dr. Tsien is currently designing imaging and therapeutic molecules that specifically target cancer cells.
The Sayer Vision Research Fund supports the annual Sayer Lecture, which is delivered by an investigator in the area of vision research. The Fund also supports the Sayer Vision Research Award, a grant-in-aid to a promising independent investigator in the early stage of his or her research career in the Division of Intramural Research at NEI. NIDDK research scientist Dr. Jane Sayer established the Fund at the Foundation for the National Institutes of Health in 2006 to honor her family and the memory of her parents, Winthrop and Laura Sayer.
For more information about the Sayer Lecture, visit: http://www.nei.nih.gov/news/special/sayer.asp.
Fourth Sayer Vision Research Lecture (NIH Only)
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- The Paradox of Immunity
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- - Dr. Jeffrey Ravetch (2010/11/18)
- - Category : Wednesday Afternoon Lectures
- Following postdoctoral studies at the NIH with Dr. Phil Leder, where he identified and characterized the genes for the human IgM antibody and the DNA elements involved in switch recombination, in 1982 Dr. Ravetch joined the faculty of Memorial Sloan-Kettering Cancer Center and Cornell Medical College. His laboratory cloned the first genes for Fc receptors, identified the SHIP inhibitory receptor signaling pathway and contributed significantly to understanding the mechanisms of antibody mediated effector responses, establishing the FcR pathways as fundamental components of the immune response. In addition to his studies on antibody receptors, Dr. Ravetch has made fundamental contributions to the genetics of the malaria parasite and with the identification of the first chemokine, IP-10, established this class of molecules as novel mediators of inflammation. He returned to The Rockefeller University in 1996 to establish the Laboratory of Molecular Genetics and Immunology.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
The Paradox of Immunity
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- Recombinant DNA Advisory Committee (RAC) March 2010 - Day 2
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- - NIH (2010/11/18)
- - Category : Recombinant DNA Advisory Committee
- The RAC is a technical committee whose goal is to consider the current state of knowledge and technology regarding recombinant DNA. This includes review of human gene transfer trials, and an assessment of the ability of DNA recombinants to survive in nature and the potential for transfer of genetic material to other organisms. It also considers hypothetical hazards and methods for monitoring and minimizing risks. Approximately one-third of the 15 members do not have scientific expertise but represent public interests and attitudes. This balance is intended to provide a forum for open public debate of social and scientific issues attendant to recombinant DNA research. The RAC has been overwhelmingly successful in achieving this goal.
For more information, visit the
Recombinant DNA Advisory Committee (RAC) Conference Web Site
Recombinant DNA Advisory Committee (RAC) March 2010 - Day 2
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- NCI Communication Roundtable Seminar: Using Decision Support and Mobile Technologies to Address Patient Care
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- - Sponsored by the NCI Communications Strategy Roundtable, Office of Communications and Education, NCI (2010/11/18)
- - Category : NCI Communication Roundtable
- Communication Researchers and Practitioners: Join researchers from the NCI-funded Center for Health Systems Research and Analysis of the University of Wisconsin in Madison.
The researchers will present findings on the benefits of online support and tailored information systems for those with chronic health conditions. They will demonstrate how individuals with life threatening illnesses use new technologies to improve quality of life and discuss the impact of mobile technology for cancer patients and their families. The primary goal of the seminar is to identify potential practical applications of these research findings.
Speakers:- David Gustafson
- Fiona McTavish
- Bret Shaw
- Dhavan Shah
- Andrew Isham
- Deborah Mayer of The Center for Health Systems Research and Analysis (CHSRA), University of Wisconsin in Madison.
NCI Communication Roundtable Seminar: Using Decision Support and Mobile Technologies to Address Patient Care
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- LTASC Overview and Task Order Process
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- - Office of Logistics and Acquisition Operations (OLAO) (2010/11/18)
- - Category : Special
- The presentation provides an overview of the Long Term Administrative Support Contract (LTASC), an NIH-wide vehicle that serves as a practical solution to long-term (at least 12 months) administrative support needs. The presentation includes a demonstration of the electronic ordering system used by customers to facilitate the task order process as well as a review of the stakeholders involved, roles and responsibilities, and the task order process.
http://ltasc.od.nih.gov
LTASC Overview and Task Order Process
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- Mouse Models of Human Disease: From Cancer to Neuropsychiatric Disorders
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- - Dr. Mario Capecchi (2010/11/18)
- - Category : Wednesday Afternoon Lectures
- Dr. Capecchi began his research at the University of Utah in 1973. Thirty-four years later, on December 10, 2007, Dr. Capecchi received the highest honor in his field, the Nobel Prize, for his work in molecular biology. His pioneering work in gene targeting of mouse embryo-derived stem cells has set a new standard for research worldwide.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Mouse Models of Human Disease: From Cancer to Neuropsychiatric Disorders