전체 8345
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- TRACO: Immunology and Colon Cancer
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- - Henkart, Pierre.
National Institutes of Health (U.S.) (2010/11/18) - - Category : TRACO
- - Henkart, Pierre.
- For more information, visit
http://ccr.cancer.gov/careers/traco.asp
TRACO: Immunology and Colon Cancer
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- Exercise is Good for the Brain as well as the Body: Effects on Gene Expression, Neural Function and Neuroprotection
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- - Cameron, Judy L.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Wednesday Afternoon Lectures
- - Cameron, Judy L.
- Talk Summary: Sure, exercise is good for toning your muscles and keeping off
those extra pounds. But good for your brain, too? Judy Cameron will talk
about how exercise increases blood flow to the brain, increases alertness and
attentiveness, and may be able to protect the brain against the development of
age-related illnesses such as Parkinsons Disease. She also will discuss
natural variation in the level of physical activity that individuals undertake,
how these differences develop, and how they affect gene expression and neural
function.
Biographical Sketch: Judy Cameron, Ph.D., is Professor of Psychiatry at the University of Pittsburgh; Senior Scientist at the Oregon National Primate Research Center; and Professor of Behavioral Neuroscience and Obstetrics & Gynecology at Oregon Health and Science University (OHSU). She also directs training programs in Womens Health Research and Reproductive Biology at OHSU. Over the past 10 years she has been a member of the MacArthur Foundation Research Network on Early Experience and Brain Development and the National Scientific Council on the Developing Child. Dr. Camerons research focuses on the effects of everyday life stresses on long-term health. Three current areas of interest in her laboratory are how exercise affects the brain; the effects of stress on reproductive function and what makes some individuals stress-sensitive whereas other individuals are stress-resilient; and effects of genetic factors and early life experiences on anxious and depressive behaviors. She also directs a large-scale collaborative genetic linkage analysis in rhesus monkeys to begin to identify chromosomal regions and eventually genes underlying various anxious behaviors and addictive behaviors, as well as related physiological measures including CSF monoamine levels and the propensity to be active versus sedentary. She has a long-term interest in understanding the interactions between physical health and mental health.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Exercise is Good for the Brain as well as the Body: Effects on Gene Expression, Neural Function and Neuroprotection
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- Genetics and Stored Tissue - 2008 (Session 8)
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- - Wilfond, Benjamin.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Bioethics
- - Wilfond, Benjamin.
- Ethical and Regulatory Aspects of Clinical Research
Department of Clinical Bioethics
This course is designed to provide a historical context for research regulations and to help researchers and others working in human subject research gain insights and skills into the development of research protocols and their ethical implementation.
Objectives of the Course:
To learn the codes, declarations, and other documents that govern the ethical conduct of human subject research; review the critical elements of informed consent and their implementation in actual informed consent documents for clinical research; explore controversial issues relating to human subject research, including Phase I research, randomization, children in research, international research, etc; review the purpose if IRBs and provide IRB-like experience in reviewing research protocols; understand the experience of human subjects who have participated in research protocols.
For more information, visit
http://www.bioethics.nih.gov
Genetics and Stored Tissue - 2008 (Session 8)
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- Transcriptional Regulation of Inflammatory T Cell Differentiation
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- - Littman, D R.
National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18) - - Category : Immunology
- - Littman, D R.
- The IIG is extremely pleased to host Dr. Dan Littman who is the Kimmel Professor of Molecular Immunology and Coordinator of the Molecular Pathogenesis Program, Skirball Institute of Biomolecular Medicine, New York University Medical Center, and an Investigator in the Howard Hughes Medical Institute. He has made extraordinary contributions to multiple areas in immunology, including the cloning of and studies related to CD4 and CD8, HIV, as well as seminal studies related to Th17 differentiation, and the Runx and RORgt transcription factors. Please join us for a most exciting talk.
For more information, visit
The Immunology Interest Group
Transcriptional Regulation of Inflammatory T Cell Differentiation
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- Survey & Certification for Indian Health Providers - Part 2
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- - Dorothy Dupree (2010/11/18)
- - Category : CMS - Centers for Medicare & Medicaid Services
- CMS Medicine Dish Series
Our January 2008 show focused primarily on hospitals. This show provides information applicable to all providers. The panel of CMS experts will present:- Overview of the Survey and Certification program,
- Differences between certification and accreditation,
- Implications for Federally Qualified Health Centers, and
- Role of CMS Regional Offices in the provider enrollment and certification processes.
Materials related to this broadcast will be posted on the CMS AI/AN website at http://www.cms.hhs.gov/AIAN/MedicineDishBroadcasts.asp.
E-mail Comments to: medicinedish@cms.hhs.gov
Survey & Certification for Indian Health Providers - Part 2
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- American Health Information Community - November 2008
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- - American Health Information Community. Meeting (2010/11/18)
- - Category : American Health Information Community
- The American Health Information Community (the Community), is a committee established under the Federal Advisory Committee Act (Pub. L. No. 92-463, 5 U.S.C., App.), by the Secretary of the Department of Health and Human Services. The Community will advise the Secretary and recommend specific actions to achieve a common interoperability framework for health information technology (IT) and serve as a forum for participation from a broad range of stakeholders to provide input on achieving interoperability of health IT. The Community is made up of 17 voting members, including the Chair, and members have been appointed by the Secretary.
The Web address for the Communitys draft charter is:
http://www.hhs.gov/healthit/ahiccharter.pdf
A complete list of members can be found at:
http://www.hhs.gov/healthit/ahic.html
American Health Information Community - November 2008
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- Lunch and Learn: Best Practices for Managing & Enjoying the Toddler Years
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- - Stephanie Cromwell (2010/11/18)
- - Category : Parenting
- The toddler years are full of wonderful milestones that also come with challenges. This seminar will incorporate the latest research into practical strategies for meeting the toddler years with success.
Handout available for download at http://videocast.nih.gov/pdf/parenting111208.pdf
Lunch and Learn: Best Practices for Managing & Enjoying the Toddler Years
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- Great Teachers - Community-Based Care for Infectious Disease and the Future of Antibiotic Resistance
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- - Farmer, Paul.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Clinical Center Grand Rounds
- - Farmer, Paul.
- Contemporary Clinical Medicine
Great Teachers
Paul Farmer, MD, PhD.
Associate Chief, Division of Global Health Equity, Brigham and Women？？？s Hospital
Presley Professor, Department of Global Health and Social Medicine, Harvard Medical School
Co-Founder, Partners in Health
For more information, visit
http://www.cc.nih.gov/about/news/grcurrent.html
Great Teachers - Community-Based Care for Infectious Disease and the Future of Antibiotic Resistance
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- Convergence of Virology and Cell Biology
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- - Foundation for the National Institutes of Health. (2010/11/18)
- - Category : Special
- The Foundation for the National Institutes of Health and the NIH Virology Interest Group announce the Tenth Annual Norman P. Salzman Memorial Award in Virology. This award has been established to recognize outstanding research accomplishment by a post-doctoral fellow or research trainee working in the field of virology at the NIH. The award honors the 40-year career of Dr. Salzman in virology research and his accomplishments in mentoring of young scientists. The award will be presented during the Symposium which is being held on Thursday, November 13, 2008 in the Natcher Main Auditorium (Building 45) on the NIH campus in Bethesda, MD. The recipient will be expected to give a 20-minute presentation based on the award-winning abstract. The symposium will also feature other prominent speakers in the field of virology. A luncheon reception will follow at 12:30 pm.
For more information, visit http://fnih.org/index.php?option=com_content&task=view&id=655&Itemid=852
Convergence of Virology and Cell Biology
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- Biomedical Technology Research Centers: Multiscale Technologies for Biomedical Research
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- - National Center for Research Resources (U.S.). Biomedical Technology. (2010/11/18)
- - Category : Special
- Biomedical Technology Research Resources and Resource Centers create critical, often unique technology and methods at the forefront of their respective fields, and apply them to a broad range of basic, translational, and clinical research. This is accomplished through a synergistic interaction of technical and biomedical expertise, both within the resources and through intensive collaborations with other leading laboratories.
Find more information about these resources at:
NIBIB Biomedical Technology Resource Centers
NCRR Biomedical Technology Research Resources
Biomedical Technology Research Centers: Multiscale Technologies for Biomedical Research
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- Welfare Reform: Long-Term Implications for the Development of Children, Adolescents and Young Adults
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- - Chase-Lansdale, P Lindsay.
National Institutes of Health (U.S.). Behavioral and Social Sciences Research Coordinating Committee. (2010/11/18) - - Category : BSSR Lecture Series
- - Chase-Lansdale, P Lindsay.
- More than a decade after the passage of the landmark welfare reform law of 1996 --the Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA)--, the long-term outcomes for children and youth are still unclear.
PRWORA had the good fortune to be launched during a period of strong economic growth. Yet, few studies have examined how children？？？s well-being may have changed under welfare reform during the post-2000 period of a sluggish economy.
Welfare, Children, and Families: A Three-City Study was designed to examine the association of mothers？？？ welfare and employment transitions with changes in child development at three time points over a six-year period, 1999 to 2005, in a random sample 2,042 children and youth in low-income families living in low- and moderate-income neighborhoods in Boston, Chicago, and San Antonio. For young children, changes in mothers？？？ welfare receipt and employment were not linked to long-term deterioration or improvement in children？？？s reading and math skills or problem behavior. For youth, the overall picture is also one of null findings in these domains. Moreover, we found no significant association between mothers？？？ welfare and employment transitions and the important youth life outcomes of teenage pregnancy, parenthood, or high school drop-out. A notable exception was that adolescents and young adults whose mothers found jobs or increased their work hours were less likely to have clinically-high levels of behavior problems than were those whose mothers remained unemployed or worked part-time. Overall, the long-term well-being of children and youth neither worsened nor improved substantially in this new era of welfare reform, suggesting that the predictions of both the proponents and the opponents of PRWORA were off the mark.
This lecture is an installment of the Behavioral and Social Sciences Research Lecture Series sponsored by the NIH Office of Behavioral and Social Sciences Research and organized by the NIH Behavioral and Social Sciences Research Coordinating Committee.
The Behavioral and Social Sciences Research Coordinating Committee (BSSR CC), with support from the Office of Behavioral and Social Sciences Research (OBSSR), convenes a series of guest lectures and symposia on selected topics in the behavioral and social sciences. These presentations by prominent behavioral and social scientists provide the NIH community with overviews of current research on topics of scientific and social interest. The lectures and symposia are approximately 50 minutes in length, with additional time for questions and discussion. All seminars are open to NIH staff and to the general public.
Welfare Reform: Long-Term Implications for the Development of Children, Adolescents and Young Adults
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- TRACO: Lymphoma and siRNA
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- - Wilson, Wyndham Hopkins.
National Institutes of Health (U.S.) (2010/11/18) - - Category : TRACO
- - Wilson, Wyndham Hopkins.
- For more information, visit
http://ccr.cancer.gov/careers/traco.asp
TRACO: Lymphoma and siRNA
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- Beating the Odds: Preparing Minorities for Research Careers in the Biomedical Sciences
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- - Hrabowski, Freeman A.
NIH Black Scientists Association. (2010/11/18) - - Category : John W. Diggs
- - Hrabowski, Freeman A.
- 2008 John W. Diggs Lecture
To highlight the accomplishments of minority scientists. This years keynote speaker Dr. Freeman Hrabowski, has been a leader in the promotion of science education for underrepresented minorities. The event will be open to the public and should be informative for anyone involved in medical or scientific research,administration or education.
Dr. Freeman Hrabowski, President of the University of Maryland, Baltimore County. Dr. Hrabowski has been President of UMBC since 1992. His highly acclaimed research and publications focus on the participation of minorities in science and mathematics.
The event is cosponsored by the NIH Office of Intramural Research, the NIH Office of Research on Womens Health, and the NIH Black Scientists Association.
Beating the Odds: Preparing Minorities for Research Careers in the Biomedical Sciences
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- Roles of Mammalian Mre11 in Genomic Stability and Development
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- - Ferguson, David.
National Institutes of Health (U.S.). DNA Repair Interest Group. (2010/11/18) - - Category : DNA Repair
- - Ferguson, David.
- The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.
Acrobat Slides
For more information, visit the
DNA Repair Interest Group
Roles of Mammalian Mre11 in Genomic Stability and Development
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- Redox Biology - NADPH oxidases and Imaging
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- - Leto, Tom.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Redox Biology
- - Leto, Tom.
- Redox Biology (RB)
The course is designed for NIH fellows to enhance their knowledge of redox biology. Reactive species such as superoxide, hydrogen peroxide and nitric oxide are associated with cellular toxicity, however, nitric oxide is useful in the treatment cardiovascular disease. The course will examine the role of reactive nitrogen and oxygen species in carcinogenesis, cancer proliferation and angiogenesis.
For more information, visit
http://ccr.cancer.gov/careers/courses/rb
Redox Biology - NADPH oxidases and Imaging
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- Office of Public Health and Science (OPHS) Honor Awards Ceremony
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- - Dr. Anand Parekh, Deputy Assistant Secretary for Health (Science and Medicine), and RADM Robert Williams, Acting Deputy Surgeon General (2010/11/18)
- - Category : Special
- The OPHS Honor Awards Ceremony is scheduled to be held on Tuesday, November 18, 2008, in the Great Hall of the Hubert H. Humphrey Building, starting at 1:00pm. The purpose of this awards ceremony is to recognize and honor OPHS employees (civilian and members of the USPHS Commissioned Corps) for outstanding achievement or services in the performance of official duties. The ceremony will be hosted by ADM Joxel Garcia, Assistant Secretary for Health; he will present awards to staff who have been approved to receive Assistant Secretary for Health Honor Awards. RADM Steven Galson, Acting Surgeon General, USPHS, is scheduled to present awards to members of the USPHS Commissioned Corps who have been approved to be recognized at this ceremony. ADM Garcia will participate in the presentation of the awards to members of the USPHS Commissioned Corps.
For more information, visit: http://www.hhs.gov/ophs/index.html
Office of Public Health and Science (OPHS) Honor Awards Ceremony
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- NIH Extramural Staff Training Seminar - Your Role and Responsibility for Handling Financial Conflict of Interest - Day 1 (HHS Only)
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- - Sally Rockey (chair), Diane Dean, Joe Ellis, Kathy Hancock, Gwynne Jenkins, Chuck Selden (2010/11/18)
- - Category : ESA (HHS Only)
- The integrity of the scientific record is critical to the conduct of science. Risks that compromise objectivity in research must be managed and the highest ethical standards must be upheld. Therefore, it is imperative that all NIH-supported Investigators and their recipient Institutions comply with the requirements of the financial conflict of interest (FCOI) regulations. Investigators must fully disclose their significant financial interests to their Institutions and Institutions must identify, manage, reduce or eliminate financial conflicts of interest and report them to NIH. Your review and oversight is a linchpin of this process. This critical training course will clarify staff roles and responsibilities in the reporting and risk management of FCOI that come to our attention through media, Congressional inquiry, publications, as well as through the receipt of a FCOI report from an NIH-supported Institution.
For more information, visit
http://odoerdb2-1.od.nih.gov/oer/training/esa/esa_training_20081021.htm
NIH Extramural Staff Training Seminar - Your Role and Responsibility for Handling Financial Conflict of Interest - Day 1 (HHS Only)
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- Resumes and Cover Letters for Industry
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- - Sponsored by the NIH Office of Intramural Training & Education (2010/11/18)
- - Category : Career Development/OITE
- Focused content regarding cover letter and resume construction targeted towards industry jobs.
Resumes and Cover Letters for Industry
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- The 4th Mitochondria Minisymposium - 2008
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- - NIH Mitochondria Minisymposium
National Institutes of Health (U.S.). Mitochondria Interest Group. (2010/11/18) - - Category : Conferences
- - NIH Mitochondria Minisymposium
- The Interaction and Independence of Sirtuins and Mitochondria: A few NIH Perspectives Convened to accentuate the Wednesday Afternoon Lecture of Leonard Guarente (MIT).
08:30-10:00 Session I: Karen Usdin (Chair)
08:30-09:00: Karen Usdin (NIDDK) The dark side of SIRT1
09:00-09:30: John Hanover (NIDDK) Sirtuins and O-GlcNAc: Interwoven threads in the fabric of the cellular stress response
09:30-10:00: Rui-Hong Wang (NIDDK): Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
10:00-10:20 Networking Break and Poster Session
10:20-11:50 Session II: Curtis Harris (Chair)
10:20-10:50: Curtis Harris (NCI): p53-dependent cellular senescence
10:50-11:20: Jaime Ross (NIDA-Karolinska Institutet): Premature aging in POLG knock-in mice
11:20-11:50: David Gius (NCI): SIRT3 is a mitochondrial tumor suppressor gene
11:50-12:40 Lunch and Poster Session (Guarente dines with Fellows)
12:40-14:40 Session III: Catherine Wolkow (Chair)
12:40-13:10: Catherine Wolkow (NIA): IIS and FOXO signaling in C. elegans: Unraveling the webs of direct and indirect targets that regulate longevity and diapauses
13:10-13:40: Mark Mattson (NIA): Adaptive stress response pathways in neurons
13:40-14:10: Vilhelm Bohr (NIA): Mitochondrial DNA Repair
14:10-14:40: Toren Finkel (NHLBI): Sirtuin regulation of mitochondrial function
14:40-14:55 Networking Break (Guarente prepares for WAL)
15:00-16:00 Wednesday Afternoon Lecture: Leonard Guarente (MIT): ？？？SIRTUINS, AGING AND DISEASE？？？
16:00-16:45 WAL Reception: Sponsored by NIH Scientific Directors
16:00-17:15: Poster Session
The 4th Mitochondria Minisymposium - 2008
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- Sirtuins, Aging and Disease
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- - Guarente, Leonard.
National Institutes of Health (U.S.) (2010/11/18) - - Category : Wednesday Afternoon Lectures
- - Guarente, Leonard.
- SIR2 and related genes are NAD-dependent deacetylases that slow aging in yeast, C. elegans, and Drosophila. In yeast and flies, SIR2 genes are also involved in the longevity conferred by dietary or calorie restriction (CR). The mammalian SIRT homologs are involved in changes in stress resistance and metabolism known to be associated with CR.
The CR diet not only extends life span in rodents, but also protects against many diseases of aging, including diabetes, cardiovascular disease, neurodegenerative disease, cancer and osteoporosis. In this talk, I will describe recent findings in the lab regarding SIRT1 function in specific mammalian tissues and in specific disease models. Our findings indicate a diverse array of effects exerted by SIRT1 in mammals.
The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Sirtuins, Aging and Disease