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  • Understanding Angiogenesis through Retinopathy
    • - Smith, Lois.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Wednesday Afternoon Lectures
    Proliferative vascular disease of the retina is a major cause of blindness in children (retinopathy of prematurity), in middle aged adults (diabetic retinopathy) and in the elderly (age-related macular degeneration). Oxygen-induced retinopathy in the mouse is a model system for both retinopathy and angiogenesis. Understanding the oxygen-regulated factors acting on the immature retina and those factors normally supplied by the in utero environment and missing after premature birth from helps define critical pathways in normal vascular development, vascular loss and neovascularization. With this model we have explored the role of Hif regulated factors such as VEGF and erythropoietin in vascular survival and the role of omega long chain polyunsaturated fatty acids and IGF-1 missing after preterm birth.

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Understanding Angiogenesis through Retinopathy

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  • DDM - Sustaining Resonant Leadership in Challenging Times (NIH Only)
    • - Annie McKee (2010/11/18)
    • - Category : DDM Seminar Series (NIH Only)
    2008-2009 Deputy Director for Management (DDM) Seminar Series

    The DDM Seminar Series is open to all NIH employees and there is no need to pre-register for the event.

    Click here to download a Survey about this DDM Seminar. Information will be used to evaluate the program and improve future seminars.

    Dr. Annie McKee is the Founder and Managing Director of Teleos Leadership Institute, executive coach, author and faculty member at the University of Pennsylvania. She advises some of the largest corporations in the world. A scholar on the cutting edge of leadership, organizational culture and change, she is dedicated to making good leaders better and world-class corporations even more successful.

    Dr. McKees latest book, Becoming a Resonant Leader, a follow-up to Resonant Leadership, is a hands- on guide to developing emotional intelligence, renewing relationships and sustaining effectiveness. She also co-authored Primal Leadership: Learning to Lead with Emotional Intelligence with Daniel Goleman and Richard Boyatzis.

    With engaging speeches and interactive seminars, Dr. McKee demonstrates that the best leaders create resonance- a reservoir of positivity that inspires passion and motivates people to perform at their best. She believes that resonant leaders do more than simply chart a strategy or manage resources-they move people, creating a deep emotional connection that is characterized by hope, a shared belief in compelling vision, and a sense that together, we can achieve anything.

    During her presentation for NIH, Dr. McKee will be sharing her insights about the following:
    • The fact that change is here and is here to stay!
    • What it takes to be a great leader
    • Myths and the truth about effective leadership
    • Tools for sustaining personal success and resonant leadership in the face of todays challenges
    This seminar is one of many efforts at the NIH in striving for management excellence and is designed to bring outstanding speakers to the NIH to discuss leadership and administrative management topics. It will provide administrative and scientific communities with the opportunity to meet with each other to discuss and exchange ideas on the topics presented.

    The DDM Seminar Series is open to all NIH employees and there is no need to pre-register for the event.

    http://www.ddmseries.od.nih.gov

    DDM - Sustaining Resonant Leadership in Challenging Times (NIH Only)

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  • Visualizing the Structures and Conformational Changes of Biological Nanomachines with CryoEM
    • - Stewart, Phoebe L.
      National Institutes of Health (U.S.). Structural Biology Interest Group. (2010/11/18)
    • - Category : Structural Biology
    The SBIG is a clearinghouse for discussions and interactions between scientists interested in all aspects of molecular structure, from experimental determination by x-ray crystallography, electron microscopy, mass spectrometry, and NMR, to theoretical and computational biology and biophysics, and to the biological application of structural data.

    For more information, visit
    Structural Biology Interest Group

    Visualizing the Structures and Conformational Changes of Biological Nanomachines with CryoEM

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  • US Repatriation State Training
    • - ACF (2010/11/18)
    • - Category : Special
    내용 없음

    US Repatriation State Training

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  • The Pandemic Threat of Avian Influenza Viruses
    • - Kanta Subbarao, M.B., B.S., M.P.H. (2010/11/18)
    • - Category : Anita B. Roberts
    The Anita B. Roberts Lecture Series

    This series highlights outstanding research achievements of women scientists at the NIH. The seminar is dedicated to Dr. Anita Roberts and honors her role as an exceptional mentor and scientist.

    Anita joined the NIH in 1976 and spent 30 years at NCI, rising to Chief of the Laboratory of Cell Regulation and Carcinogenesis. She died of gastric cancer in May 2006, leaving a legacy that touched both the professional and personal lives of all who knew her. Her work focused primarily on TGF-beta and its role in the growth of epithelial and lymphoid cells. In 2003, Thomas Scientifics Science Watch listed her among the 50 most-cited scientists during 1982 to 2002, a feature called Twenty Years of Citation Superstars.
    Anita was a superstar to many for her mentoring talent and her ability to balance family and work life. Her successful lab was well known for meeting family needs and for providing an environment both intellectually and emotionally enriching. The lecture series in her name serves to highlight the fact that the NIH recognizes the value and necessity of a supportive workplace.

    For more information, visit
    http://www1.od.nih.gov/oir/sourcebook/comm-adv/wsa.htm

    The Pandemic Threat of Avian Influenza Viruses

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  • The National Eye Institutes 40th Anniversary Symposium: Genetics and Genomics in Vision
    • - National Eye Institute. (2010/11/18)
    • - Category : Conferences
    The first 40th anniversary symposium offered geneticists, biologists, clinicians, and clinician-scientists an opportunity to examine the impact of genetics research on vision research.

    Agenda:
    Morning Session
    Chairperson: Paul Sieving, M.D., Ph.D., Director, NEI, NIH

    WELCOME ADDRESS
    Paul Sieving, M.D., Ph.D., Director, NEI, NIH


    KEYNOTE ADDRESS
    Aravinda Chakravarti, Ph.D., Professor,？？？Departments of Medicine, Pediatrics, and Molecular Biology and Genetics
    Director, Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine
    Genetic Screens of Disease Genes and Modifiers

    CLINICAL PERSPECTIVE
    Stephen Ryan, M.D., Grace and Emery Beardsley Professor of Ophthalmology, University of Southern California and Doheny Eye Institute
    Genetic Discoveries and Translational Research

    RETINAL DEGENERATION IN SYNDROMIC DISEASES
    Val Sheffield, M.D., Ph.D., Professor, Department of Pediatrics, University of Iowa
    Investigator, Howard Hughes Medical Institute
    The Blind Leading the Obese: The Molecular Pathophysiology of Bardet-Biedl Syndrome

    Thomas Friedman, Ph.D., Chief, Laboratory of Molecular Genetics, National Institute of Deafness and Other Communication Disorders, NIH
    Usher syndrome: a molecular genetic junction of vision and hearing research

    PRESENTATIONS BY NEI FELLOWS
    Dr. Mary Mattapallil, M.D.V., Ph.D., Research Fellow, Immunoregulation Section, Laboratory of Immunology, NEI Genetic interactions influence development of autoimmune uveitis: lessons from animal models

    Rivka Rachel M.D., Ph.D., Staff Scientist, Neurobiology-Neurodegeneration & Repair Laboratory, NEI
    Pathogenesis of retinal degeneration in the rd16 mouse: a model for syndromic disorders caused by mutations in the centrosomal-ciliary protein CEP290/NPHP6

    Afternoon Session Chairperson: Sheldon Miller, Ph.D., Scientific Director, Division of Intramural Research, NEI, NIH

    INSIGHTS IN EYE GENETICS
    Mark Daly, Ph.D., Assistant Professor of Medicine,？？？Harvard Medical School and Massachusetts General Hospital
    Human Genetics Promise and Progress

    Joan Bailey-Wilson, Ph.D., Head, Statistical Genetics Section, National Human Genome Research Institute, NIH
    Genetic studies of myopia and refractive error: the present and the future.

    Elizabeth Engle, M.D., Professor of Neurology and Ophthalmology, Harvard Medical School, Investigator, Howard Hughes Medical Institute
    Family-based studies of strabismus

    PRESENTATIONS BY NEI FELLOWS
    Brian P. Brooks, M.D., Ph.D., Chief, Pediatric, Developmental and Genetic Ophthalmology Section, Laboratory of Ophthalmic Genetics and Visual Function, NEI
    Expression profiling during ocular development identifies Two Nlz genes with a critical role in optic fissure closure

    James Friedman, Ph.D., Research Fellow, Neurobiology-Neurodegeneration & Repair Laboratory, NEI
    Mutations in a novel BTB-Kelch protein, KLHL7, cause autosomal dominant retinitis pigmentosa

    PANEL DISCUSSION
    Moderators: Hemin Chin, Ph.D., Director, Ocular Genetics Program, Division of Extramural Research, NEI, NIH

    Elizabeth Phimister, Ph.D., Deputy Editor, New England Journal of Medicine

    OVERVIEW AND CONCLUDING REMARKS
    Paul Sieving, M.D., Ph.D., Director, NEI, NIH

    The National Eye Institutes 40th Anniversary Symposium: Genetics and Genomics in Vision

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  • NIH Directors Council of Public Representatives - April 2009
    • - National Institutes of Health (U.S.). Directors Council of Public Representatives. (2010/11/18)
    • - Category : NIH Directors Council of Public Representatives
    The Directors Council of Public Representatives (COPR) is a federal advisory committee made up of members of the public, who advise the National Institutes of Health (NIH) Director on issues related to public participation in NIH activities, outreach efforts, and other matters of public interest.

    For more information, visit
    http://copr.nih.gov

    NIH Directors Council of Public Representatives - April 2009

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  • Raising The Bar in Drug Discovery and Development for Mood Disorders: A Translational Perspective
    • - Zarate, Carlos A.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    Mood disorders (Bipolar Disorder and Major Depressive Disorder) are common, chronic, recurrent mental illnesses that affect the lives of millions of individuals worldwide. Even with adequate modern pharmacological therapies, a disproportionate number of afflicted individuals continue to have persistent mood episode relapses, residual symptoms, functional impairment, psychosocial disability, and suicidal behavior, with tragic concomitant increases in morbidity and mortality. Although novel therapeutics that are mechanistically distinct and work more quickly and effectively are desperately needed for individuals with mood disorders, the discovery and development of such therapeutics has unfortunately reached a plateau. This lecture will summarize some of the promising Intramural efforts currently being developed, as well as explore some exciting future directions in the discovery and development of novel therapeutics to address this urgent, unmet need. Notably, such proof-of-concept studies also incorporate new, cutting-edge research technologies to analyze and measure affective, cognitive, and behavioral components of mood disorders in relationship to potential biomarkers of response.

    Raising The Bar in Drug Discovery and Development for Mood Disorders: A Translational Perspective

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  • Public Meeting on Clinical Trials
    • - National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Conferences
    The National Institutes of Health (NIH) of the U.S. Department of Health and Human Services (HHS) announces a public meeting and requests input from interested parties on regulations to be developed to expand the clinical trial registry and results data bank commonly known as ClinicalTrials.gov in accordance with provisions contained in section 801 of the Food and Drug Administration Amendments Act of 2007 (FDAAA). FDAAA requires the Secretary of HHS to hold a public meeting to provide an opportunity for input from interested parties with regard to regulations to be issued within three years of enactment of the law. NIH is seeking input from all parties with an interest in clinical trials information on a range of issues to be considered in the rulemaking, including the possible inclusion of results information for clinical trials of drugs, biological products and devices that are not approved by the FDA, the submission of narrative summaries of the results of applicable clinical trials, adverse event reporting, and modifications to the registration information that is required to be submitted to the data bank.

    The agenda is posted at http://prsinfo.clinicaltrials.gov/public-meeting-april09.html

    Public Meeting on Clinical Trials

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  • Competition and Compensation Between the Neural Circuitry that Supports Pavlovian Fear Conditioning
    • - Fanselow, Michael S.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Neuroscience
    Dr. Fanselow？？？s laboratory is generally interested in learning, memory and motivation and particularly in the nature and function of fear and emotional memories. We are motivated by questions such as: How does the brain process fear-provoking information and what neurobiological changes lead to the formation and storage of fear memories? More than simply tracing the anatomical circuits and neurotransmitter systems mediating fear, we are trying to determine the specific contributions that different components of the circuit contribute to the complete experience of an emotional memory. For example, the hippocampus is not always involved in the expression of fear; it seems to come into play when fear is triggered by the memory of the context or episode of an aversive experience and not when a simple association generates fear. The amygdala seems to encode the emotional features of an aversive experience. The anterior cingulate cortex seems to be involved in attentional processes necessary for more complex forms of conditional fear. The midbrain periaqueductal gray organizes how fear is translated into specific behavior patterns. While glutamate is the critical neurotransmitter for the creation of fear memories, GABA, endogenous opioids, acetylcholine and corticotropin releasing hormone (CRH) all regulate fear learning. We have laboratory projects directed at all of these subsystems. The laboratory uses rat and mouse models featuring site-specific pharmacological manipulations, focal brain lesions and genetic modifications. Much of the current work examines behavior in genetically modified mice. But our mission is to use every technique available to derive a complete understanding of fear-motivated learning, memory and behavior.

    Selected Publications:
    Rau, V. & Fanselow, M. S. (2007) Neurobiological and neuroethological perspectives on fear and anxiety. In L. J. Kirmayer, R. Lemelson, & M. Barad, Understanding Trauma: Integrating biological, clinical, and cultural perspectives (pp. 27-40). Cambridge University Press: New York.

    Wiltgen BJ, Sanders MJ, Anagnostaras SG, Sage JR, Fanselow MS. Context fear learning in the absence of the hippocampus. J Neurosci. 2006 May 17;26(20):5484-91.

    Gale, G. D., Anagnostaras, S. G., Godsil, B. P., Mitchell, S., Nozawa, T., Sage, J. R., Wiltgen, B., Fanselow, M. S. (2004) Role of the Basolateral Amygdala in the Storage of Fear Memories across the Adult Lifetime of Rats. J. Neurosci. 2004 24: p. 3810-3815.

    Fanselow MS, LeDoux JE. Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala. Neuron. 1999; 23:229-232.

    Fendt M, Fanselow MS. The neuroanatomical and neurochemical basis of conditioned fear. Neuroscience and Biobehavioral Reviews. 1999; 23:743-760.

    Li HH, Yu W-H, Rozengurt N, Zhao H-Z, Lyons KM, Anagnostaras S, Fanselow MS, Suzuki K, Vanier MT, Neufeld EF. Mouse model of Sanfilippo syndrome type B produced by targeted disruption of the gene encoding alpha -N-acetylglucosaminidase. Proceedings of the National Academy of Sciences, USA. 1999; 96:14505-14510.

    For more information see our website - NIH Neuroscience Seminar Series

    Competition and Compensation Between the Neural Circuitry that Supports Pavlovian Fear Conditioning

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  • NED Super User Update (NIH-Only)
    • - Richie Taffet, HSPD-12 Program Manager (2010/11/18)
    • - Category : NIH Only
    This session will provide an update on HSPD-12 implementation at NIH and provide details on the upcoming rollout of the new HHS ID Badge. The AO Sponsor community will be the first group to receive the new badges. This session will highlight the essential role that NED Super Users play the next phase of the rollout.

    NED Super User Update (NIH-Only)

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  • Town Hall Meeting and Information Session: BTRIS, the NIH Biomedical Translational Research Information System
    • - Lowe, Henry.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Special
    The Biomedical Translational Research Information System (BTRIS) team invites you to a series of lectures focused on informatics in biomedical and translational research. This series brings leading 詮？gures in the study and use of translational information systems from academic centers across the U.S. and will promote discussion about the future of informatics at the Clinical Center.

    Learn more about how BTRIS will be developed, opportunities for investigators to participate in its design, and project goals.

    For more information, visit http://btris.nih.gov

    Town Hall Meeting and Information Session: BTRIS, the NIH Biomedical Translational Research Information System

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  • Demystifying Medicine - Excema and the skin microbiome
    • - Komarow, Hirsh.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Demystifying Medicine
    The course includes presentation of patients, pathology, diagnosis and therapy in the context of major disease problems and current research. Primarily directed toward Ph.D. students, fellows, and staff, it is also of interest to medical students and clinicians. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components which are presented by NIH staff and outside invitees.

    For more information, visit
    http://www1.od.nih.gov/oir/DemystifyingMed

    Demystifying Medicine - Excema and the skin microbiome

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  • Behavioral Intervention for Symptom Management: Examining the Mechanism of Action (NIH-Only)
    • - Given, Barbara A.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : NCI CCR Grand Rounds (NIH Only)
    Barbara Given is a University Distinguished Professor in the College of Nursing. Dr. Given has been actively involved in research in long-term care, home care, chronic illness and family care for over 29 years with funding from the National Cancer Institute, National Institute on Mental Health, National Institute for Nursing Research, National Institute on Aging, Walther Cancer Foundation, Michigan Department of Community Health, and the American Cancer Society to explore these issues. Topics of research center around functional outcomes, symptom control, patterns of care, utilization of care, and formal and informal cost of care for the chronically ill and their family caregivers, especially those with cancer. She is a reviewer for numerous professional journals and currently serves on the Editorial Board for Research in Nursing and Health, and Cancer Nursing. She has served as a grant reviewer for AHCPR, Psychosocial Research for the American Cancer Society, National Cancer Institute, NINR, Department of Defense, National Institute of Aging, California Cancer Research Program, and the Alzheimer？？？s Association of Canada. Barbara Given testified to the President？？？s Breast Cancer Commission and the President？？？s Cancer Panel for Older Populations in 1997 and served on the Institute of Medicine？？？s Department of Defense Panel to decide on priorities for breast cancer research funding. She served on the Breast Cancer Integrating Panel for the Department of Defense and the psychosocial outcomes committee for NSABP. She also served on the Blue Ribbon Panel for ACS to set direction for research for Behavioral and Psychosocial Research. She served on the Institute of Medicine to examine cancer care outcomes in Georgia. Recently she presented on Family Caregivers of the Elderly to the Cancer Policy Panel.

    She recently participated in the State of the Science on Family Caregivers sponsored by AARP, Hartford and ANA. She serves on the Executive Committee of the Behavioral Cooperative Oncology Group of the Walther Cancer Foundation. In 1994, she was the American Nursing Foundation Distinguished Researcher Award Recipient and in 1995, the ONS Distinguished Researcher and the Michigan Association of Governing Boards Distinguished Faculty Award recipient. In 2000, she received the College of Nursing Alumni Lifetime Achievement Award at Michigan State University. In 2001, she received the University Distinguished Professor award, the Sigma Theta Tau Elizabeth Williams Miller Award for Excellence in Research and the Friends of the National Institute for Nursing Research Pathfinder Distinguished Researcher Award. In 2005, she received the Oncology Nursing Outstanding Service Award. Dr. Given is currently involved with the Honorary Degree Committee at Michigan State University and received the Oncology Nursing Society Distinguished Service Award in 2006. Dr. Given was named the Vanderbilt University School of Nursing Martha Rivers Ingram Visiting Professor in the spring of 2008. She presented to the National Cancer Policy Forum of the Institute of Medicine on Caregiving in Elderly Cancer Patients in October 2006. She is currently a member of the Caregiving National Advisory Committee of the AARP and the Council on Social Work Education.

    SELECTED REFERENCES:
    1. Jeon, S., Given, C. Sikorskii, A. and Given, B. (2009). Do Interference Based Cut-points Differentiate Mild, Moderate, and Severe Levels of 16 Cancer-Related Symptoms Over Time? Journal of Pain and Symptom Management, 37(2), 220-232. NIHMSID: NIHMS97442
    2. Given, C.W., Sikorskii, A., Tamkus, D., Given, B., You, M., McCorkle, R., Champion, V. and Decker, D. (2008). Managing Symptoms Among Breast Cancer Patients During Chemotherapy: Results of a Two Arm Behavioral Trial. Journal of Clinical Oncology. 26(36), 5855-5862. PMC In Process
    3. Given, B., Given, C.W., Sikorskii, A., Jeon, S., McCorkle, R., Champion, V., Decker, D. (2008). Establishing mild, moderate, and severe scores for cancer related symptoms: How consistent and clinically meaningful are interference-based severity cut-points? Journal of Pain and Symptom Management, 35(2), 126-135. (Impact Factor is 2.324). NIHMS 40473 PMCID: PMC2635012
    4. Sikorskii, A., Given, C., Given, B., Jeon, S., Decker, V., Decker, D., Champion, V., McCorkle, R. (2007). Symptom management for cancer patients: A trial comparing two multimodal interventions. Journal of Pain and Symptom Management, 34(3), 253-264. (Impact Factor is 2.437).

    NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link:
    http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx

    Behavioral Intervention for Symptom Management: Examining the Mechanism of Action (NIH-Only)

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  • Regulation of Eukaryotic Base Excision Repair via Dynamic Compartmentalization
    • - Doetsch, Paul W.
      National Institutes of Health (U.S.). DNA Repair Interest Group. (2010/11/18)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group


    Acrobat Slides

    Regulation of Eukaryotic Base Excision Repair via Dynamic Compartmentalization

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  • Planet in Crisis: The Case for Investing in Global Health During a Financial Meltdown
    • - Professor Jeffrey Sachs (2010/11/18)
    • - Category : Special
    Notable economist, best-selling author and global health advocate Jeffrey Sachs will visit NIH on April 22 as a Fogarty International Center Scholar-in-Residence, part of its 40th anniversary activities. The event is sponsored by the Foundation for NIH.

    ？？？Planet in Crisis: The Case for Investing in Global Health During a Financial Meltdown？？？

    Professor Jeffrey Sachs
    Director of the Earth Institute
    Quetelet Professor of Sustainable Development Professor of Health Policy and Management at Columbia University

    Professor Sachs is director of the Earth Institute, Quetelet professor of sustainable development, and professor of health policy and management at Columbia University. For more than 20 years he has been in the forefront of the challenges of economic development, poverty alleviation, and enlightened globalization, promoting policies to help all parts of the world to benefit from expanding economic opportunities and wellbeing. He is also one of the leading voices for combining economic development with environmental sustainability, and as director of the Earth Institute leads large-scale efforts to promote the mitigation of human-induced climate change.

    He is the author of hundreds of scholarly articles and many books, including the New York Times bestsellers ？？？Common Wealth: Economics for a Crowded Planet？？？ and ？？？The End of Poverty.？？？ Sachs is a member of the Institute of Medicine and is a Research Associate of the National Bureau of Economic Research.

    The event is sponsored by the Foundation for NIH with generous support from Lilly, the Abbott Fund, Bristol-Myers Squibb Foundation, ExxonMobil, Pepsico, Aeras Global TB Vaccine Foundation, the Burroughs Wellcome Fund, Merck, Pfizer, Tibotec and the United Nations Foundation.

    Planet in Crisis: The Case for Investing in Global Health During a Financial Meltdown

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  • Innate Host Defense: Mechanisms and Pathways
    • - Medzhitov, Ruslan. (2010/11/18)
    • - Category : Wednesday Afternoon Lectures
    Innate immune system provides the first line of host defense against microbial infections. Several classes of microbial sensors of the innate immune system have now been identified.

    Upon activation, these sensors directly induce anti-microbial mechanisms. In addition, they trigger activation of inflammatory response, as well as activation of adaptive immunity. The complex interplay between microbial pathogens, innate immune sensors and activation of the adaptive immune responses will be the subject of this lecture.

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Innate Host Defense: Mechanisms and Pathways

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  • Personal genome profiles: Transdisciplinary science issues (HHS-Only)
    • - National Cancer Institute (U.S.). Public Health Genomics Interest Group. (2010/11/18)
    • - Category : HHS Only
    This is the 6th session of the 2008-2009 NIH Seminar Series: Advances in Public Health Genomics

    Muin J. Khoury, M.D., Ph.D.
    Office of Public Health Genomics, CDC
    Division of Cancer Control and Population Sciences, NCI

    and

    Colleen McBride, Ph.D
    Social and Behavioral Research Branch, NHGRI

    For more information, visit http://dccps.cancer.gov/od/phg/seminar.html

    Personal genome profiles: Transdisciplinary science issues (HHS-Only)

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  • CC Grand Rounds: (1) Dangers of Secret Science: Case Study of Hemoglobin-Based Blood Substitutes, (2) Leukocyte Antibodies and Transfusion Reactions
    • - Natanson, Charles.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Grand Rounds

    Charles Natanson, MD
    Senior Investigator and Chief, Anesthesia Section
    Critical Care Medicine Department, CC

    David Stroncek, MD
    Chief, Cell Processing Section, Department of Transfusion Medicine, CC

    For more information, visit
    http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: (1) Dangers of Secret Science: Case Study of Hemoglobin-Based Blood Substitutes, (2) Leukocyte Antibodies and Transfusion Reactions

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  • 2009 Simplified Acquisition Symposium (HHS-Only)
    • - Sponsored by OLAO, OD, NIH and NCI. (2010/11/18)
    • - Category : HHS Only
    8:30 am Welcome: Ed Wilgus, Acting Director, Division of Simplified Acquisition Policy & Services
    Opening Remarks: Colleen Barros, NIH Deputy Director for Management
    Administrative Professionals Day Recognition: Dr. Lawrence Tabak, Acting NIH Deputy Director & Director NIDCR
    9:00 am Green Purchasing: Dana Arnold, Federal Environmental Executive (Acting)
    9:35 am Awards Ceremony: Diane Frasier, Director Office of Acquisition & Logistics Management, and HCA
    10:00 am Awards Reception
    10:20 am American Recovery and Reinvestment Act: Nancy Gunderson, Acting Deputy Assistant Secretary for Acquisition Management & Policy, and Acting Senior Procurement Executive
    10:55 am Purchase Card Update: Ronda Boatright, Acting Chief NIH Purchase Card Program, and Agency Program Coordinator

    For more information, visit http://olao.od.nih.gov/Training/AcquisitionTraining

    2009 Simplified Acquisition Symposium (HHS-Only)

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