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  • Dan Ihde Memorial Lecture: Lung Cancer in Smokers and Never Smokers: Two Different Diseases (NIH-Only)
    • - Gazdar, Adi F.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : NCI CCR Grand Rounds (NIH Only)
    Dr. Adi Gazdar was born in Bombay, India. After obtaining his medical training at Guys Hospital, University of London, he did a residency in pathology at Harvard Medical School, Boston. For several years he worked as a Medical Investigator at the NCI-Navy Medical Oncology Branch, National Cancer Institute, Maryland. In 1991 he joined the University of Texas Southwestern Medical Center, Dallas, where he has an endowed chair in the Department of Pathology and serves as Deputy Head of the Hamon Center for Therapeutic Oncology Research. He is the recipient of the Mary Matthews award from the International Association for the Study of Lung Cancer and the Jacqueline Seroussi Foundation for his contributions to lung cancer research.

    Dr. Gazdar？？？s research interests center on understanding the multistage pathogenesis of human malignancies, with a special interest in lung and breast cancers. He has published nearly 650 medical articles, including more than 300 in the field of lung cancer. The Institute for Scientific Information includes Dr. Gazdar in a list of the worlds most cited authors--comprising less than one half of one percent of all publishing researchers, based on the important scientific developments of the last two decades. He serves as an Associate Editor for several journals including Cancer Research, International Journal of Cancer and Clinical Cancer Research. His major interests include the role of methylation as a mechanism of silencing of tumor suppressor genes, markers for early diagnosis and risk assessment and deregulation of the Epidermal Growth Factor Gene signaling pathway in the pathogenesis of lung and other cancers. He serves as the Principal Investigator of a newly launched multiplatform, multi-institutional approach to study lung cancer in never smokers, funded jointly by the National Cancer Institute and the Canary Foundation.

    SELECTED REFERENCES:
    1. Subramanian J, Govindan R. Molecular genetics of lung cancer in people who have never smoked. The Lancet Oncology 2008; 9:676？？？82.
    2. Sun S, Schiller JH, Gazdar AF. Lung cancer in never smokers - a different disease. Nature Reviews 2007; 7: 778？？？90. Yano T, Miura N, Takenaka T, Haro A, Okazaki H, Ohba T, Kouso H, Kometani T, Shoji F, Maehara Y. Never-smoking nonsmall cell lung cancer as a separate entity: clinicopathologic features and survival. Cancer 2008; 113: 1012？？？8.

    NCI？？？s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link:
    http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx

    Dan Ihde Memorial Lecture: Lung Cancer in Smokers and Never Smokers: Two Different Diseases (NIH-Only)

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  • The Role of UV In Melanoma Induction In Xeroderma Pigmentosum Patients
    • - Wang, Yun.
      National Institutes of Health (U.S.). DNA Repair Interest Group. (2010/11/18)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group

    Acrobat Slides

    The Role of UV In Melanoma Induction In Xeroderma Pigmentosum Patients

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  • Artemis Function in DNA Repair and Immunogenesis
    • - Yannone, Steve.
      National Institutes of Health (U.S.). DNA Repair Interest Group. (2010/11/18)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group

    Acrobat Slides

    Artemis Function in DNA Repair and Immunogenesis

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  • A Novel Cofactor and Diverse Nucleic Acid Interactions of CSB, a Human Swi/Snf2 Protein
    • - Brian R. Berquist, NIA, NIH (2010/11/18)
    • - Category : DNA Repair
    The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.

    For more information, visit the
    DNA Repair Interest Group

    Acrobat Slides

    A Novel Cofactor and Diverse Nucleic Acid Interactions of CSB, a Human Swi/Snf2 Protein

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  • Breast Cancer Prevention and Treatment with Noni Juice
    • - Wang, Mian-Ying.
      National Cancer Institute (U.S.). Office of Cancer Complementary and Alternative Medicine. (2010/11/18)
    • - Category : OCCAM Monthly Lecture Series
    The NCIs Office of Cancer Complementary and Alternative Medicine (OCCAM) invites you to view its monthly lecture series.

    With the goal of informing the National Cancer Institute (NCI) community about the variety of ongoing research in cancer and complementary and alternative medicine (CAM), NCIs Office of Cancer Complementary and Alternative Medicine (OCCAM) has created a monthly lecture series on cancer CAM. These hour long lectures, occurring from 10 a.m. - 11 a.m. on the second Wednesday of each month, will feature a fifty minute presentation on a cancer CAM topic and allow ten minutes for questions.

    For more information, visit
    http://www.cancer.gov/cam/news/monthly-lecture-series.html

    Breast Cancer Prevention and Treatment with Noni Juice

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  • Powered by NCBC - the Human Studyome Using Tools from the National Center for Biomedical Ontology
    • - Dr. Ida Sim, University of California, San Francisco (2010/11/18)
    • - Category : Special
    The NIH Roadmap National Centers for Biomedical Computing (NCBC) Lecture Series Presents: ？？？Computerizing the Human Studyome Using Tools from the National Center for Biomedical Ontology？？？

    The human studyome is the totality of all human studies worldwide, encompassing all interventional, observational and qualitative research on human subjects. The human studyome is one of the most valuable sources of knowledge for advancing the understanding of diseases and treatments. To support efficient and effective use of human studies data, the human studyome needs to be computerized for large-scale discovery, reanalysis, and reuse.

    Dr. Sim is a leader in the representation of human studies for scientific computation. In this talk, she will discuss her Driving Biological Project with the National Center for Biomedical Ontology, one of the seven NCBC Centers funded under the NIH Roadmap Initiatives, to use ontologies to visualize design heterogeneity in randomized trials. She will also discuss some observations on the benefits and challenges of applying ontologies and ontology tools to computerizing the human studyome and to clinical research in general.

    Dr. Sim is an Associate Professor of Medicine and Director, Center for Clinical and Translational Informatics at the University of California, San Francisco. She received her MD and her PhD in Medical Informatics from Stanford University, and her Primary Care Internal Medicine training from the Massachussetts General Hospital. She is also fellowship-trained in General Internal Medicine at Stanford University. Her research focus is on knowledge-based technologies for clinical research and evidence-based practice. She received the United States Presidential Early Career Award for Scientists and Engineers (PECASE) in 2000 for her work on The Trial Bank Project, which developed fundamental informatics technologies for a computable knowledge base of randomized trials. She has since led multiple projects related to semantic standards and visualization methods for clinical research, clinical trial reporting bias, new models of scientific e-publication of clinical research, and work on the adoption of electronic health records in primary care practices for quality improvement. In policy work, Dr. Sim was the founding Project Coordinator of the World Health Organization？？？s International Clinical Trials Registry Platform, which sets global standards on clinical trial registration and reporting. Dr. Sim serves on the editorial board of the Journal of Biomedical Informatics, is on the Advisory Board for PLoS One, and is a Fellow of the American College of Medical Informatics.

    For more information, visit http://www.ncbcs.org/

    Powered by NCBC - the Human Studyome Using Tools from the National Center for Biomedical Ontology

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  • Healthier OHR: When You Cant Exercise, Deskercise! (NIH Only)
    • - Julie Broussard Berko and Laura Lavrin (2010/11/18)
    • - Category : Human Resources (NIH Only)
    OHR Brown Bag Session

    Healthier OHR: When You Cant Exercise, Deskercise! (NIH Only)

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  • Medicare Part A Billing
    • - Kitty Marx (2010/11/18)
    • - Category : CMS - Centers for Medicare & Medicaid Services
    CMS Medicine Dish Series

    TrailBlazer Health Enterprises and CMS presenters will cover:
    • How to bill for Part A outpatient and inpatient services,
    • How to bill for services outside of the All Inclusive Rate,
    • Top 10 Part A billing errors,
    • Federally Qualified Health Center enrollment tips,
    • Medicare billing verification programs, and
    • Technical assistance for providers in Indian Country.
    Presenters:
    • Kitty Marx, Host, Tribal Affairs Director, OEA CMS
    • Pamela Davis, Provider Outreach & Education, TrailBlazer Health Enterprises
    • David Nolley, Office of External Affairs, CMS
    For more information, visit www.cms.hhs.gov/AIAN/10_MedicineDishBroadcasts.asp.

    E-mail Comments to: medicinedish@cms.hhs.gov

    Medicare Part A Billing

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  • T cell clonotypic correlates of virus control in SIV infection
    • - Douek, Daniel.
      National Institutes of Health (U.S.). Immunology Interest Group. (2010/11/18)
    • - Category : Immunology
    Dr. Douek is a recognized leader in the field of human immunology. His laboratory, the Human Immunology Section, studies the processes that determine the course of human diseases in which the immune system, particularly its T cell arm, plays a central role in their pathogenesis and outcome. He aims to use the knowledge gained to initiate clinical studies of new therapeutic and vaccine approaches. His overriding philosophy is to address questions directly in humans and non-human primates, with an emphasis on the derivation of the basic mechanisms that underlie disease processes. Currently, the main focus of the lab is the pathogenesis of HIV infection. By studying interactions of HIV-specific T cells in HIV disease and after vaccination against HIV, Dr. Doueks aim is to establish correlates of effective and protective immunity, which in turn will open lines of further inquiry for researchers in developing strategies using T-cell immunity to fight HIV infection. By studying the mechanisms underlying HIV pathogenesis and immune reconstitution after therapy, his goal is to understand how HIV causes disease and how recovery from HIV disease can be enhanced. Together, these approaches address both prevention and treatment of HIV disease in humans. In 2007 Dr. Douek was given the World AIDS Day Award.

    For more information, visit
    The Immunology Interest Group

    T cell clonotypic correlates of virus control in SIV infection

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  • HSF and the Balancing Act between Neurodegeneration and Cancer
    • - Dr. Susan Lindquist, Whitehead Institute for Biomedical Research (2010/11/18)
    • - Category : Wednesday Afternoon Lectures
    Susan Lindquist, professor of Biology at MIT, member of the Whitehead Institute and Howard Hughes Medical Institute investigator, is a pioneer in the study of protein folding. After receiving her B.A. in Microbiology from the University of Illinois in 1971, Lindquist completed her Ph.D. in Biology at Harvard University. In 1978 she finished her postdoctoral fellowship at the University of Chicago. Lindquist？？？s contributions to the field include showing that changes in protein folding can have profound and unexpected influences in fields as wide-ranging as human disease, evolution and nanotechnology. In fact, through Lindquist？？？s research, protein misfolding has been implicated as a major mechanism in many severe neurological disorders, including Parkinson？？？s and Huntington？？？s diseases.

    Lindquist and her colleagues have developed yeast strains that serve as living test tubes to study these disorders, unraveling how protein folding contributes to them. They have succeeded in reproducing many of the biological consequences of Parkinson？？？s disease in yeast cells and are screening for drugs to prevent and treat the disease.

    Lindquist？？？s bench work has lead to publishing more than 150 scholarly articles, editing two books, writing more than 50 reviews, and having more than 20 current and pending patents.

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    HSF and the Balancing Act between Neurodegeneration and Cancer

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  • Great Teachers - Sixth Annual John Laws Decker Memorial Lecture: Transplanted Allogeneic T-cells Identify a Viral Corpse Resurrected in Renal Cell Carcinoma
    • - Childs, Richard.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Clinical Center Grand Rounds
    Contemporary Clinical Medicine: Great Teachers

    Richard W. Childs, MD
    Chief, Section of Transplantation Immunotherapy, Hematology Branch,
    , and Captain Select, US Public Health Service

    For more information, visit
    http://www.cc.nih.gov/about/news/grcurrent.html

    Great Teachers - Sixth Annual John Laws Decker Memorial Lecture: Transplanted Allogeneic T-cells Identify a Viral Corpse Resurrected in Renal Cell Carcinoma

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  • National Cancer Advisory Board - June 2009
    • - The National Cancer Institute (NCI) Division of Extramural Activities (2010/11/18)
    • - Category : National Cancer Advisory Board
    This is a regularly scheduled meeting of the National Cancer Advisory Board (NCAB).

    National Cancer Advisory Board - June 2009

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  • Mid-Career Financial Planning Seminar
    • - E. David Walter, Jr (2010/11/18)
    • - Category : NIH Only
    These seminars will provide important financial planning information so that employees can analyze their financial health as well as their retirement readiness.

    Mid-Career Financial Planning Seminar

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  • Enrichment, Veterinary Medicine and the Science of Animal Welfare (HHS-Only)
    • - Weed, Jim.
      National Institutes of Health (U.S.). Animal Well-Being Interest Group. (2010/11/18)
    • - Category : HHS Only
    Animal Well-being Scientific Interest Group Seminar

    The animal well-being scientific interest group seminar for 2009 focuses on how we assess environmental enrichment; the interface of enrichment with veterinary care in the research environment; and the application of science to the welfare of animals.

    For more information, visit
    http://fmp-8.cit.nih.gov/awig/index.html

    Enrichment, Veterinary Medicine and the Science of Animal Welfare (HHS-Only)

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  • National Advisory Child Health and Human Development Council Meeting - June 2009
    • - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2010/11/18)
    • - Category : National Advisory Child Health and Human Development Council
    The NICHD Advisory Council has two specific functions: (1) to advise the NICHD on policy and procedures affecting the extramural research programs and (2) to provide the second level of review for grant applications requesting Institute funding support. The Council meets for one day three times a year in January, June, and September.

    The morning session is Open to the Public and is devoted to bringing Council members up-to-date with a Report of the Director, NICHD, a report by the Council Subcommittee on Planning and Policy, a review of one of the extramural program areas, discussion and review of proposed concepts for NICHD initiatives, the annual review of the Board of Scientific Counselors reports on intramural research programs, and new business items identified by the Council membership and Institute staff. The afternoon session is closed to the Public for the confidential Review of Applications.

    For more information, visit http://www.nichd.nih.gov/about/overview/advisory/nachhd/virtual-meeting-200905.cfm.

    National Advisory Child Health and Human Development Council Meeting - June 2009

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  • Basic Investing & Retirement Planning Seminar
    • - Reena Oettinger, Financial Advisor, Old Dominion Investment Corporation (2010/11/18)
    • - Category : NIH Only
    These seminars will provide important financial planning information so that employees can analyze their financial health as well as their retirement readiness.

    Basic Investing & Retirement Planning Seminar

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  • Materials to Regulate Cell Trafficking In Vivo: From Regeneration to Immunotherapies
    • - Dr. David Mooney, Harvard University (2010/11/18)
    • - Category : Special
    NIDCR 2009 Seminar Series: From Basic Research to Therapy -- The Latest Frontier

    An expert in bioengineering, Dr. Mooney will discuss his work on designing versatile, active biomaterials that can program cells in vivo to survive, divide, differentiate, and migrate to specific sites in the body to heal and regenerate tissues. Dr. Mooney？？？s laboratory is investigating the use of these innovative biomaterials for applications ranging from regenerative medicine to immunotherapy. (For additional information, see Dr. Mooney？？？s abstract at: http://www.nidcr.nih.gov/NewsAndFeatures/Announcements/MooneyAbstract.htm)

    Dr. Mooney is the Gordon McKay Professor of Bioengineering in the School of Engineering and Applied Sciences at Harvard University. He is also a faculty member of Harvard？？？s Wyss Institute for Biologically Inspired Engineering.

    For more information, visit http://www.nidcr.nih.gov/NewsAndFeatures/Announcements/NewSeminarSeries.htm

    Materials to Regulate Cell Trafficking In Vivo: From Regeneration to Immunotherapies

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  • Cell-Cell Signaling Underlying Synapse Formation and Function
    • - Balice-Gordon, Rita.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Neuroscience
    Dr. Balice-Gordon research interest is focused on the role of activity in the control of synaptic plasticity during neural development. Using neuromuscular and CNS synapses in mice and zebrafish as model systems she has analyzed cell-cell signaling mechanisms that control synapse formation and maintenance. Her work with Jeff Lichtman using in-vivo imaging to show that inactive synapses are eliminated is now in neuroscience text-books. Her current work continues to focus on the neuronal and glial interactions that control synapse formation. These studies are important to our understanding of circuit formation and neural re-innervation after injury.

    NIH Neuroscience Seminar Series

    Cell-Cell Signaling Underlying Synapse Formation and Function

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  • Self-Renewal Pathways in Blood Stem Cells
    • - Leonard Zon, M.D., Grousbeck Professor of Pediatric Medicine, Childrens Hospital Boston, Harvard Medical School (2010/11/18)
    • - Category : Stem Cell
    The Stem Cell Interest Group was established to enhance communication and to foster collaboration among scientists from varying disciplines interested in stem cells. Topics of interest include fundamental stem cell biology, ontogeny, gerontology, and the therapeutic potential of stem cells. The SCIG serves as an open forum for discussion and dissemination of knowledge about all aspects of stem cell biology

    For more information, visit
    http://tango01.cit.nih.gov/sig/home.taf?_function=main&SIGInfo_SIGID=115

    Self-Renewal Pathways in Blood Stem Cells

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  • Using Communication Research to Design Effective Messages for Public Health: The cases of HPV vaccine and anti-smoking PSAs
    • - Cappella, Joseph N.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : BSSR Lecture Series
    The success of public health campaigns depends in part on how the information central to the campaign is communicated and the psychological and social resistance to that information that exists in the targeted audience. The crafting of successful messages in public communication campaigns is certainly an art but one that must be constrained by scientific knowledge about audiences and their susceptibility and resistance to message formats and content. Research on two cases will be presented: public anti-smoking efforts and the introduction of the HPV vaccine.

    Joseph N. Cappella (Ph.D., 1974, Michigan State University) is Professor of Communication and holds the Gerald R. Miller Chair at the Annenberg School for Communication at The University of Pennsylvania. He has been a visiting professor at the University of Pennsylvania and Northwestern University and a visiting scholar at Stanford. His research has resulted in more than 100 articles and book chapters and three co-authored books in areas of health and political communication, social interaction, nonverbal behavior, media effects, and statistical methods. The articles have appeared in journals in psychology, communication, health, and politics. His research has been supported by grants from NIMH, NIDA, NSF, NCI, NHGRI, The Twentieth Century Fund, and from the Markle, Ford, Carnegie, Pew, and Robert Wood Johnson foundations. He has served on the editorial boards of 15 different journals. He is a Fellow of the International Communication Association and its past president, a distinguished scholar of the National Communication Association, and recipient of the B. Aubrey Fisher Mentorship Award.

    This lecture is an installment of the Behavioral and Social Sciences Research Lecture Series sponsored by the NIH Office of Behavioral and Social Sciences Research and organized by the NIH Behavioral and Social Sciences Research Coordinating Committee.

    The Behavioral and Social Sciences Research Coordinating Committee (BSSR CC), with support from the Office of Behavioral and Social Sciences Research (OBSSR), convenes a series of guest lectures and symposia on selected topics in the behavioral and social sciences. These presentations by prominent behavioral and social scientists provide the NIH community with overviews of current research on topics of scientific and social interest. The lectures and symposia are approximately 50 minutes in length, with additional time for questions and discussion. All seminars are open to NIH staff and to the general public.

    Using Communication Research to Design Effective Messages for Public Health: The cases of HPV vaccine and anti-smoking PSAs

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