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  • Chronic Fatigue Syndrome Advisory Committee Meeting (Day 1)
    • - United States. Dept. of Health and Human Services. Chronic Fatigue Syndrome Advisory Committee. (2010/11/18)
    • - Category : Chronic Fatigue Syndrome Advisory Committee
    The Chronic Fatigue Syndrome Advisory Commitee was established to provide science-based advice and recommendations to the Secretary of Health and Human Services and the Assistant Secretary for Health on a broad range of issues and topics pertaining to chronic fatigue syndrome (CFS). Topics include: (1) the current state of knowledge and research about the epidemiology and risk factors relating to CFS, and identifying potential opportunities in these areas; (2) current and proposed diagnosis and treatment methods for CFS; and (3) development and implementation of programs to inform the public, health care professionals, and the biomedical, academic and research communities about CFS advances. The Committee meets twice a year, spring and fall.

    For more information, visit: http://www.hhs.gov/advcomcfs/

    Chronic Fatigue Syndrome Advisory Committee Meeting (Day 1)

  • Chronic Fatigue Syndrome Advisory Committee Meeting (Day 2)
    • - Wanda K. Jones, DrPH, Deputy Assistant Secretary for Health (Womens Health), Office of Public Health and Science (2010/11/18)
    • - Category : Chronic Fatigue Syndrome Advisory Committee
    The Chronic Fatigue Syndrome Advisory Commitee was established to provide science-based advice and recommendations to the Secretary of Health and Human Services and the Assistant Secretary for Health on a broad range of issues and topics pertaining to chronic fatigue syndrome (CFS). Topics include: (1) the current state of knowledge and research about the epidemiology and risk factors relating to CFS, and identifying potential opportunities in these areas; (2) current and proposed diagnosis and treatment methods for CFS; and (3) development and implementation of programs to inform the public, health care professionals, and the biomedical, academic and research communities about CFS advances. The Committee meets twice a year, spring and fall.

    For more information, visit: http://www.hhs.gov/advcomcfs/

    Chronic Fatigue Syndrome Advisory Committee Meeting (Day 2)

  • National Advisory Research Resources Council - May 2009
    • - National Advisory Research Resources Council. (2010/11/18)
    • - Category : National Advisory Research Resources Council
    National Advisory Research Resources Council

    During the May 28, 2009, meeting of the National Advisory Research Resources Council, NCRR staff will provide an update on activities related to the American Recovery and Reinvestment Act of 2009. Other presentations will focus on training and career development from K-12 through the professional levels.

    The meeting also will feature an update on the IDeA program, including an overview of the National Association of IDeA principal investigators, Web site and communications activities, and a presentation on innovation in biomedical research. Additional highlights will include Vanderbilt University???s work to advance T1 translational research through public/private partnerships, as well as updates on NCRR meetings.

    For more information, visit
    http://www.ncrr.nih.gov/about_us/advisory_council/

    National Advisory Research Resources Council - May 2009

  • Asian Pacific American Heritage Month (HHS-Only)
    • - Moritsugu, Kenneth.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : PSC Programs (HHS Only)
    Program Support Center

    Asian Pacific American Heritage Month

    Asian Pacific American Heritage Month (HHS-Only)

  • New Grantee Workshop: Working Together to Advance Cancer Control Research (Day 2)
    • - National Cancer Institute, Division of Cancer Control and Population Sciences (2010/11/18)
    • - Category : Conferences
    The Division of Cancer Control and Population Sciences (DCCPS) New Grantee Workshop (NGW) will bring together investigators that were awarded their first R01 in 2007 and 2008. At the workshop, grantees will interact with each other and program staff to discuss their research; learn about the grants process; and develop strategies for future success. The major focus of the meeting is to provide junior investigators with the tools, techniques, and information they need to successfully manage their current grant and secure subsequent funding.

    New Grantee Workshop: Working Together to Advance Cancer Control Research (Day 2)

  • Forward Genetics Reveals Novel Mechanisms of Neurodegeneration
    • - Ackerman, Susan.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Neuroscience
    Dr. Ackerman received her Ph.D. from UCLA and did postdoctoral training at the University of Illinois at Chicago, the University of Pennsylvania, and the Wistar Institute. She was a visiting scientist at the Max Planck Institute in Freiburg. She joined the Jackson Laboratory in 1993 and has been a Hughes Investigator since 2005. She has served as a member of the NIH Developmental Brain Disorders Study Section and is currently a member of the NINDS Board of Scientific Counselors. Dr. Ackermans laboratory focuses on the investigation of mechanisms underlying the development and maintenance of neurons in the cerebellum. She uses a mouse model system to identify genes that are required for the proper migration of neurons from where they are formed to where they will function in the adult. In addition, she is analyzing mice with mutations that contribute to neurodegeneration to better understand how neurons are lost in the aging mammalian brain. Current research efforts focus on the roles of oxidative stress and protein misfolding in aging and neurodegenerative disease.

    Selected Publications:

    Ackerman SL, Kozak LP, Przyborski SA, Rund LA, Boyer BB, Knowles BB. 1997. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein. Nature 386: 838-842.

    Klein JA, Longo-Guess CM, Rossmann MP, Seburn KL, Hurd RE, Frankel WN, Bronson RT, Ackerman SL. 2002. The harlequin mouse mutation down-regulates apoptosis-inducing factor. Nature 419:367-374.

    Zhao L, Longo-Guess C, Harris BS, Lee JW, Ackerman SL. 2005. Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nat Genet 37:974-979.

    Lee JW, Beebe K, Nangle LA, Jang J, Longo-Guess CM, Cook SA, Davisson MT, Schimmel P, Ackerman SL. 2006. Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature 443:50-55.

    Ishimura R, Martin GR, Ackerman SL. 2008. Loss of apoptosis inducing factor results in cell type-specific neurogenesis defects. J Neurosci. 28:4938-4948.

    For more information see our website -http://neuroseries.info.nih.gov

    Forward Genetics Reveals Novel Mechanisms of Neurodegeneration

  • Trends in the Use of Complementary and Alternative Medicine: Data from the National Health Interview Survey
    • - Richard Nahin, Ph.D., M.P.H., National Center for Complementary and Alternative Medicine (2010/11/18)
    • - Category : NCCAM Lectures
    The National Center for Complementary and Alternative Medicine presents the Complementary and Integrative Medicine Consult Service lecture series. The series provides NIH Clinical Center staff with the opportunity to learn more about how the integration of various complementary and alternative medicine treatments can affect approaches into the research and practice of medicine.

    The National Health Interview Survey is the primary U.S. Government survey to monitor the Nation???s health on an annual basis. In both 2002 and 2007, a large set of supplemental questions were added to the NHIS in order to capture data on the U.S. public???s use of complementary and alternative medicine (CAM). Using data from the 2002 and 2007 NHIS, we will explore what types of CAM therapies are used, the reasons for this use, the cost of this use, and the relation of this use to the use of conventional treatments. The impact of these data on the research community, on policy makers, and on health care insurance coverage will be discussed.

    Trends in the Use of Complementary and Alternative Medicine: Data from the National Health Interview Survey

  • Families and Health: New Directions in Research and Theory (Day 1)
    • - Sponsored by Demographic and Behavioral Sciences Branch (DBSB), Center for Population Research (CPR), NICHD; National Center for Marriage Research (NCMR), Bowling Green State University; Office of the Assistant Secretary of Planning and Evaluation, DHHS (2010/11/18)
    • - Category : Conferences
    This conference provides a unique opportunity to examine the broad implications of family structure, processes, and policies for physical and mental health over the life course by bringing together leading sociologists, psychologists, economists, physicians, epidemiologists, and policy experts, as well as representatives from major foundations. The six sessions will facilitate disciplinary cross-talk about cutting-edge research and current controversies in the rapidly evolving study of families and health. Each session will feature four internationally renowned scholars who bring distinctive yet complementary perspectives.

    Session topics include:
    • Families, Households, and Living Arrangements
    • Family Change and Instability
    • Family Relationships
    • Caring for Families: Sharing the Burden
    • New Directions in Research Methods
    • The Future of Families and Health Research
    Conference agenda available here.

    For more information, visit http://ncmr.bgsu.edu/events/families_and_health.html

    Families and Health: New Directions in Research and Theory (Day 1)

  • NEI 40th Anniversary Symposia Series: Advances in Optical Imaging and Biomedical Science (Day 1)
    • - Sponsored by the National Eye Institute and the National Institute of Biomedical Imaging and Bioengineering (2010/11/18)
    • - Category : Conferences
    This joint NEI/NIBIB symposium will focus on high resolution imaging of complex biological systems and describe advances at the theoretical, technical, and clinical levels that bridge technology and clinical diagnosis critical for ophthalmology and a growing number of medical fields. High resolution non-invasive functional imaging technology of significant diagnostic value includes laser scanning confocal/ magnetic resonance/2-photon microscopy, optical coherence tomography, speckle microscopy, and adaptive optics. These techniques and others have proven valuable in the diagnosis and treatment of diverse disease states. Symposium presentations will describe recent novel approaches to create high resolution temporal and spatial images to study a range of cells, organs, and tissues throughout the body.

    For more information, visit http://www.nei.nih.gov/anniversary/symposia/optical_imaging.asp

    NEI 40th Anniversary Symposia Series: Advances in Optical Imaging and Biomedical Science (Day 1)

  • Families and Health: New Directions in Research and Theory (Day 2)
    • - Sponsored by Demographic and Behavioral Sciences Branch (DBSB), Center for Population Research (CPR), NICHD; National Center for Marriage Research (NCMR), Bowling Green State University; Office of the Assistant Secretary of Planning and Evaluation, DHHS (2010/11/18)
    • - Category : Conferences
    This conference provides a unique opportunity to examine the broad implications of family structure, processes, and policies for physical and mental health over the life course by bringing together leading sociologists, psychologists, economists, physicians, epidemiologists, and policy experts, as well as representatives from major foundations. The six sessions will facilitate disciplinary cross-talk about cutting-edge research and current controversies in the rapidly evolving study of families and health. Each session will feature four internationally renowned scholars who bring distinctive yet complementary perspectives.

    Session topics include:
    • Families, Households, and Living Arrangements
    • Family Change and Instability
    • Family Relationships
    • Caring for Families: Sharing the Burden
    • New Directions in Research Methods
    • The Future of Families and Health Research
    Conference agenda available here.

    For more information, visit http://ncmr.bgsu.edu/events/families_and_health.html

    Families and Health: New Directions in Research and Theory (Day 2)

  • NEI 40th Anniversary Symposia Series: Advances in Optical Imaging and Biomedical Science (Day 2)
    • - Sponsored by the National Eye Institute and the National Institute of Biomedical Imaging and Bioengineering (2010/11/18)
    • - Category : Conferences
    This joint NEI/NIBIB symposium will focus on high resolution imaging of complex biological systems and describe advances at the theoretical, technical, and clinical levels that bridge technology and clinical diagnosis critical for ophthalmology and a growing number of medical fields. High resolution non-invasive functional imaging technology of significant diagnostic value includes laser scanning confocal/ magnetic resonance/2-photon microscopy, optical coherence tomography, speckle microscopy, and adaptive optics. These techniques and others have proven valuable in the diagnosis and treatment of diverse disease states. Symposium presentations will describe recent novel approaches to create high resolution temporal and spatial images to study a range of cells, organs, and tissues throughout the body.

    For more information, visit http://www.nei.nih.gov/anniversary/symposia/optical_imaging.asp

    NEI 40th Anniversary Symposia Series: Advances in Optical Imaging and Biomedical Science (Day 2)

  • Celebrating Plain Language at the NIH Award Ceremony 2009
    • - Capehart, Jonathan.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Plain Language
    This year???s keynote speaker is Jonathan Capehart, award winning editorial writer for The Washington Post. At this year???s ceremony we will again honor a group of NIH employees who have developed communication products that are exceptional for their clarity and reader focus. The event will conclude with a reception.

    For more information about the NIH Plain Language Initiative, visit http://www.nih.gov/icd/od/ocpl/resources/clearcommunication/plainlanguage.htm

    Celebrating Plain Language at the NIH Award Ceremony 2009

  • Epidemiology at the Interface of Science, Policy, and Politics: Are New Directions Needed for Epidemiology Training Today?
    • - Gordis, Leon.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Wednesday Afternoon Lectures
    Dr. Gordis served as chairman of the Department of Epidemiology in the JHU School of Hygiene and Public Health for 18 years and as Associate Dean for Admissions and Academic Affairs in the JHU School of Medicine for 6 years. He developed, and for 13 years co-directed, Physician and Society, a required 4-year course in the JHU School of Medicine. For 11 years, Dr. Gordis directed the Robert Wood Johnson Clinical Scholars Program at Johns Hopkins.

    Dr. Gordis received a B.A. from Columbia University, a Bachelor of Hebrew Literature degree from the Jewish Theological Seminary in New York City, an M.D. from the State University of New York and a Master of Public Health (MPH) and Doctor of Public Health (DrPH) from the JHU School of Hygiene and Public Health. His current research interest is the impact of uncertainty on the translation of scientific data into public policy. He served as a member of the United States Preventive Services Task Force.

    Dr. Gordis has taught introductory epidemiology at Johns Hopkins to more than 17,000 medical students and public health students over 32 years. He has taught introductory epidemiology to Federal and to State judges in courses that were developed following the Supreme Court???s Daubert ruling. He is the author of several books including a textbook, Epidemiology, now in its fourth edition. He co-authored the chapter on Epidemiology for the Reference Manual on Scientific Evidence published by the Federal Judicial Center and its revision for the second edition. He is now co-authoring the revision of this chapter for the coming third edition of the Reference Manual. He served as President of the American Epidemiological Society and the Society for Epidemiologic Research. Dr. Gordis is a member of the Institute of Medicine and a Fellow of the American Association for the Advancement of Science.

    The NIH Directors Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

    Epidemiology at the Interface of Science, Policy, and Politics: Are New Directions Needed for Epidemiology Training Today?

  • Bs, Ts, Tolls and DCs in Systemic Autoimmunity
    • - Mark Shlomchik, Professor of Laboratory Medicine & Immunobiology, Yale University School of Medicine (2010/11/18)
    • - Category : Immunology
    Mark Shlomchik is an outstanding B cell expert with a primary focus on autoimmunity. Mark was first in reporting an antibody-independent role of B cells in autoimmune disease. Stemming from his in-depth analysis of an anti-rheumatoid factor transgenic mouse model, he described the prevalence of somatic hypermutated antibody responses in the absence of germinal centers. He has studied the various stages of B cell development, including the germinal center reaction, plasma cells and memory B cells using a variety of approaches: flow cytometry and expression analysis of specific populations, analysis of antibody sequences and cell imaging. Most recently, he has found divergent roles for TLR9 and TLR7 in the lupus autoimmune disease, and has reported on the use of B cell depletion therapy in treatment for diabetes. Come to hear his talk and give the B cells some love!

    For more information, visit
    The Immunology Interest Group

    Bs, Ts, Tolls and DCs in Systemic Autoimmunity

  • CC Grand Rounds: (1) Genomic and Transcriptional Evolution of Metastatic Melanoma: A Case Study, (2) Biomarkers of Parkinson Disease and Related Disorders
    • - Wang, Ena.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Clinical Center Grand Rounds
    Clinical Center Grand Rounds

    Ena Wang, MD
    Staff Scientist and Director of Molecular Science, Infectious Diseases and Immunogenetics Section,
    Department of Transfusion Medicine, CC

    David S. Goldstein, MD
    Senior Investigator and Chief,
    Clinical Neurocardiology Section, NINDS

    For more information, visit
    http://www.cc.nih.gov/about/news/grcurrent.html

    CC Grand Rounds: (1) Genomic and Transcriptional Evolution of Metastatic Melanoma: A Case Study, (2) Biomarkers of Parkinson Disease and Related Disorders

  • Advisory Committee to the Director of the NIH - June 2009
    • - Advisory Committee to the Director, National Institutes of Health. Meeting (2010/11/18)
    • - Category : Advisory Committee to the Director of the NIH
    A meeting of the Advisory Committee to the Director (ACD) of the National Institutes of Health (NIH)

    The agenda for the meeting will be posted at a later date on the ACD Web site at
    http://www.nih.gov/about/director/acd/index.htm

    Advisory Committee to the Director of the NIH - June 2009

  • Improving Spoken English
    • - Sponsored by the NIH Office of Intramural Training & Education (2010/11/18)
    • - Category : Career Development/OITE
    Objective: Designed for non-native, English speaking scientists, this session offers helpful hints on improving spoken English. The seminar includes tips on diction and pronunciation of scientific words. After the seminar, youll have the opportunity to sign up for additional practice.

    Presented by Scott Morgan

    Improving Spoken English

  • Receptors, Synapses and Memories
    • - Huganir, Richard.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Neuroscience
    Dr. Huganirs laboratory is interested in the mechanisms that regulate synaptic transmission and synaptic plasticity. The general approach they have taken is to study molecular and cellular mechanisms that regulate neurotransmitter receptors. These receptors mediate the response of neurons to neurotransmitters released at synapses and are a central convergence point for transmission of signals between neurons. Modulation of the function of these receptors is a powerful and efficient way to modulate synaptic communication and synaptic plasticity. Over the years they have shown that receptor protein phosphorylation and the regulation of the synaptic targeting of receptors are dynamically regulated and regulate the efficiency of synaptic transmission. They are currently focusing their efforts on the mechanisms that underlie the regulation of the glutamate receptors, the major excitatory neurotransmitter receptors in the brain. These receptors are neurotransmitter-dependent ion channels that allow ions to pass through the neuronal cell membrane, resulting in the excitation of neuronal activity.

    Selected Publications:

    Sia GM, Beique JC, Rumbaugh G, Cho R, Worley PF, Huganir RL. Interaction of the N-terminal domain of the AMPA receptor GluR4 subunit with the neuronal pentraxin NP1 mediates GluR4 synaptic recruitment. Neuron. 2007 Jul 5;55(1):87-102.

    Boehm J, Kang MG, Johnson RC, Esteban J, Huganir RL, Malinow R. Synaptic incorporation of AMPA receptors during LTP is controlled by a PKC phosphorylation site on GluR1. Neuron. 2006 Jul 20;51(2):213-25.

    Steinberg JP, Takamiya K, Shen Y, Xia J, Rubio ME, Yu S, Jin W, Thomas GM, Linden DJ, Huganir RL. Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression. Neuron. 2006 Mar 16;49(6):845-60.

    Rumbaugh, G., Adams, J.P., Kim J.H., Huganir, R.L. (2006) SynGAP Regulates Synaptic Strength and Mitogen-Activated Protein Kinases in Cultured Neurons. Proc. Natl. Acad. Sci. USA. 103(12): 4344-51.

    Hayashi T, Rumbaugh G, Huganir RL. Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites. Neuron. 2005 Sep 1;47(5):709-23.

    Kim CH, Takamiya K, Petralia RS, Sattler R, Yu S, Zhou W, Kalb R, Wenthold R, Huganir R. Persistent hippocampal CA1 LTP in mice lacking the C-terminal PDZ ligand of GluR1. Nat Neurosci. 2005 Aug;8(8):985-7.

    For more information see our website -http://neuroseries.info.nih.gov

    Receptors, Synapses and Memories

  • Evolution Matters
    • - Hillis, David M.
      National Institutes of Health (U.S.) (2010/11/18)
    • - Category : Evolution and Medicine
    How is evolution relevant to everyday life? Dr. Hillis argues that evolution is central to responding to the threat of emerging diseases, for solving certain crimes, and for identifying agents of bioterrorism, among other uses. Dr. Hillis shares applications of evolution to real life issues and explains why it is critical for tomorrow???s citizens to understand the relationships of living things.

    Dr. David Hillis is the Alfred W. Roark Centennial Professor and Director of the Center for Computational Biology and Bioinformatics at the University of Texas at Austin.

    Lecture series presented by National Institute of General Medical Sciences, the Office of Science Education, and the National Human Genome Research Institute. For more information, visit
    http://www.nigms.nih.gov/News/Meetings/EvolutionSeries2009

    Evolution Matters

  • Discussion on the Prevention and Treatment of Mental and Substance Use Disorders and Health Reform
    • - United States. Substance Abuse and Mental Health Services Administration. (2010/11/18)
    • - Category : Special
    Webcast of meeting to discuss issues outlined in Ensuring U.S. Health Reform Includes Prevention and Treatment of Mental and Substance Use Disorders ??? A Framework for Discussion: Core Consensus Principles, inform you about the various pieces of legislation being discussed by Congress and the Administration; and most importantly to continue the dialogue.

    For more information, visit http://www.samhsa.gov/Healthreform/index.aspx

    Discussion on the Prevention and Treatment of Mental and Substance Use Disorders and Health Reform